1 research outputs found
A Clinico-pathological Study of Papulonodular Lesions of Skin in a Rural Hospital Setup
Introduction: Skin disorders are a common cause of morbidity
in our country, High prevelance of dermatological lesions is seen
in tropical countries. The spectrum of lesions varies significantly
depending on the geographical region, so accurate diagnosis
is of utmost importance as treatment is varied for different skin
disorders presenting with similar clinical findings.
Aim: To study the spectrum of papulonodular lesions of
skin and to evaluate concordance between the clinical and
histopathological diagnosis of papulonodular skin lesions.
Materials and Methods: This prospective cross-sectional study
was conducted in Department of Pathology at MVJ Medical
College and Research Hospital, Hoskote, Karnataka, India,
from October 2017 to September 2019. The study included 100
skin biopsies that had clinically presented as papules, nodules
and as papulonodular lesions. Based on the histopathological
findings the lesions were grouped according to aetiology and the
final histopathological diagnosis was compared with the clinical
diagnosis offered. The slides were stained with Haematoxylin
and Eosin, examined under a microscope and findings were
noted. Special stains on the tissue sections like Zeihl-Neelson
and Fite Faraco were used when required. The qualitative
characteristics presented using frequency and percentages,
quantitative variables presented using Mean±SD.
Results: In the 100 biopsies studied 77 cases were papular, 20
cases were nodular and 3 cases were both papular and nodular.
The lesions were common in males (54%) with 67% being in
the 21-50 years age group. Lesions were categorised into
five aetiological groups based on histology i.e. non infectious
papulosquamous (25%), eczematous (23%), Inflammatory
(20%), Infectious (11%) and lastly neoplastic (21%). A clinicopathological association of 79% was observed with differences
mainly observed in the eczematous group and tumours.
Conclusion: This study highlights the various common skin
disorders that can present as papulonodular lesions and the
significance of histopathological examination and clinicopathological association for early diagnosis and management
of skin lesions