NEW DATA ON AGE AND NATURE OF CARBONIZATION WITHIN SOUTHERN FLANK OF THE BAIKAL LEDGE OF THE SIBERIAN CRATON BASEMENT

The Baikal ledge rock formations in the Siberian craton structure are included in the Akitkan mobile belt which is considered as the Late Paleoproterozoic independent island arc system moved up to the ancient basement during the terrains amalgamation 1.91–2.00 Ga ago (Fig. 1) [Rosen, 2003; Gladkochub et al., 2009; Didenko et al., 2013].The Baikal ledge rock formations in the Siberian craton structure are included in the Akitkan mobile belt which is considered as the Late Paleoproterozoic independent island arc system moved up to the ancient basement during the terrains amalgamation 1.91–2.00 Ga ago (Fig. 1) [Rosen, 2003; Gladkochub et al., 2009; Didenko et al., 2013]

Physical activity in preshoolers’ values system: questionnare survey

Objective of the study was to analyze the preschoolers’ values system and role of physical activity in the values syste

Quantitative electroencephalography indicators in children with acute purulent meningitis

The aim of the present work was to assess the state of brain bioelectrical activity in children during the acute period of bacterial purulent meningitis, with quantitative mathematical analysis of the changes found. The studies included 31 children on days 1 and 6 from onset of illness: 16 children (8.9 ± 2.4 years) admitted to the Pediatric Scientifi c Clinical Center for Infectious Diseases with laboratory confi rmation of diagnoses of purulent meningitis (due to Neisseria meningitidis) (n = 11) or Streptomyces pneumoniae (n = 2) or unidentifi ed pathogen (n = 3)), along with 15 healthy childre

ISOTOPE COMPOSITION OF CARBON AND OXYGEN IN CALCITES OF ALKALINE ULTRAMAPHIC DYKES WITHIN THE URIK-IYA GRABEN

The isotope composition of carbon and oxygen was studied in calcite of dykes and veins of ultramafic lamprophyres, kimberlite, alkaline mica picrites from the Yarma above-intrusion zone, and pyroxene-free picrites intruding the rocks of the Bolshetagninsky carbonatite massif within the Urik-Iya graben hosted by the East Sayan Mountains. The data on δ13C (from −6.6 to −3.9 ‰ relative to VPDB) disclose the ideas on the mantle origin of the carbonate substance of dykes. High values of δ18O (from +13.9 to +11.8 ‰ relative to VSMOW) suggest the impact of deuteric fluids, i.e. magmatic fluids separated from melts, at later stage of formation of the calcite-bearing alkaline ultramafic rocks

Importance of human herpes virus identification in frequently ill children

The question concerning the role of human herpes viruses in frequently ill children population remains open. We examined 179 children aged 1 to 5 years using polymerase chain reaction with DNA identification of cytomegalovirus (CMV), Epstein-Barr virus (EBV), and human herpes virus 6 (HHV6); we also performed quantitative DNA indication of CMV, EBV, and HHV6 in 102 children. We found significantly higher rates of human herpes virus associations (CMV, EBV, HHV6) in nasopharyngeal samples of frequently ill children '(53%) compared to those of episodically ill children (32,5%) (p<0,05). MHV6 DNA in nasopharyngeal samples was indicatedm 60% of episodically ill children versus 27% of frequently ill children (p<0,05). The median viral load of CMV DNA in nasopharyngeal samples of frequently ill children was Ig2,54 DNA copies/105 cells (IQR 2,04-3,23) and appeared to be lowerthan the viral load of both EBV DNA Ig3,33 DNA copies/105 cells (IQR 2,9-4,21) (p<0,05) and HHV6 DNA Ig3,4 DNA copies/105 cells (IQR 2,91-3,98) (p<0,05).Остается открытым вопрос роли вирусов герпеса в формировании группы часто болеющих детей. Проведено обследование методом полимеразной цепной реакции 179 детей в возрасте от 1 года до 5 лет с определением DNA цитомегаловируса (CMV), Эпштейн-Барр вируса (EBV), вируса герпеса 6 типа (HHV6) и количественной индикацией CMV, EBV, HHV6 у 102 детей. Установлена высокая частота выявления ассоциаций вирусов герпеса (CMV, EBV, HHV6) в соскобах со слизистой ротоглотки у часто болеющих детей (53%) в сравнении с эпизодически болеющими детьми (32,5%) (р<0,05). Определение DNA HHV6 в соскобах со слизистой ротоглотки превалировало у ЭБД- 60% против 29% (р<0,05). Медиана вирусной нагрузки DNA CMV в соскобах со слизистой ротоглотки у часто болеющих детей составила Ig2,54 копий DNA/105 клеток (IQR 2,04-3,23) и была ниже, чем вирусная нагрузка DNA EBV Ig3,33 копий DNA/105 клеток (IQR 2,9-4,21) (р<0,05) и DNA HHV61дЗ,4 копий DNA/105 клеток (IQR 2,91-3,98) (р<0,05)

Prevalence of herpes virus infections in children from preschool institutions

60 children aged 3 to 5 years attending a preschool institution were examined using PCR with quantitative DNA human herpes virus 6 (HHV6), cyto-megalovirus (CMV), and Epstein-Вагг virus (EBV) indication. The frequency of DNA HHV6, CMV, EBV identification in nasopharyngeal samples was high and equal to more than 100 DNA copy /105 cell in 93% of children. DNA HHV6 was prevailing in the structure of herpes viruses (53% of children), herpes virus associations were less frequent: DNA HHV6, CMV was identified in 17% of children, DNA HHV6, EBV in 13% of children, DNA HHV6, CMV, EBV in 3% of children; DNA CMV, EBV in 2% of children, DNA EBV in 3% of children, and DNA CMV in 2% of children. The median viral load of DNA HHV6 in nasopharyngeal samples of children was Ig3,3 DNA copy/105 cell, DNA CMV Ig2,77 DNA copy/105 cell, and DNA EBV Ig2,9 DNA copy/105 cell. The resistance index was higher in children whose nasopharyngeal samples were studied for various DNA HHV6, CMV, EBV associations (0,53±0,07) compared to that in children whose nasopharyngeal samples were studied only for DNA HHV6 identification (0,38+0,05).Проведено обследование методом полимеразной цепной реакции 60 детей в возрасте от 3 до 5 лет, посещающих детское дошкольное учреждение, с количественной индикацией DNA вируса герпеса 6 типа (HHV6), цитомегаловируса (CMV) и Эпштейн-Барр вируса (EBV). Установлена высокая частота выявления DNA HHV6, CMV, EBV в соскобах со слизистой ротоглотки - у 93% детей в количестве более 100 копий DNA/105 клеток. В структуре герпесвирусов превалирует определение DNA HHV6 - у 53% детей, ассоциации герпесвирусов встречаются реже: DNA HHV6, CMV -17%, DNA HHV6, EBV -13%, DNA HHV6, CMV, EBV - 3%; DNA CMV, EBV - 2%, DNA EBV - 3%, DNA CMV - 2%. Медиана вирусной нагрузки DNA HHV6 в соскобах со слизистой ротоглотки у детей составила Ig3,3 копий DNA/105 клеток, DNA CMV 1д2,77 копий DNA/105 клеток и DNA EBV 1д2,9 копий DNA/105 клеток.Индекс резистентности у детей с выявлением различных ассоциаций DNA HHV6, CMV, EBV в соскобах со слизистой ротоглотки выше (0,53±0,07), чем у детей с определением только DNA HHV6 (0,38+0,05)

Acquired hypopituitarism in a child with secondary hypocorticism after removal of intra-extraventricular (stem) craniophargeoma

This article presents a case of manifestation of acquired hypopituitarism (STH deficiency, secondary hypocorticism, secondary hypothyroidism, diabetes insipidus), accompanied by morbid obesity and its complications: insulin resistance, impaired glucose tolerance, dyslipidemia, secondary arterial hypertension, non-hypertension, non-hypertension, and bilateral epiphysiolysis of the hip joints occurred after removal of the intra-extraventricular craniopharyngeoma in a child after removal after removal of the intraekstraventrikulyarnoy (after beating) kraniofaringeomyВ данной статьей представлен случай манифестации приобретенного гипопитуитаризма (СТГ-дефицит, вторичный гипокортицизм, вторичный гипотиреоз, несахарный диабет), сопровождающегося морбидным ожирением и его осложнениями: инсулинорезистентностью, нарушением толерантности к глюкозе, дислипидемией, вторичной артериальной гипертензией, неалкогольной жировой болезнью печени, стеатогепатитом, двусторонним эпифизиолизом тазобедренных суставов возникла после удаления интра-экстравентрикулярной краниофарингеомы у ребенка после удаления после удаления интра-экстравентрикулярной (стебельной) краниофарингеомы

The effect of a complex of active metabolites of vitamin D3 with vikasol on the periodontal state of rats

Purpose of the study. The study of the periodontoprotective properties of the complex of a mixture of active metabolites of cholecalciferol - 1,25 (OH)2D3 and 24,25(OH)2D3 with a synthetic analogue of vitamin K - vikasol in experimental periodontitis in rats. Materials and methods The study was carried out on 18 white male rats for 1.5 months. age, divided into 3 groups. Group 1 (4 individuals) comprised intact rats. In the rats of the 2nd and 3rd groups (7 individuals each), the parodontitis model was reproduced by oral administration of a 10% solution of pelentane, and also by replacing drinking water with a 2% solution of EDTA ad libitum. In group 3, rats were injected daily with a mixture of hormonal forms of vitamin D3 (1,25 (OH)2D3 and 24,25(OH)2D3) against a background of combined effects of pelentane and EDTA. The duration of the experiment was 60 days. Results and conclusions. It is established that the complex of a mixture of two hormonal-active forms of cholecalciferol with vikasol has significant periodontoprotective properties. The obtained data substantiate the inclusion of vitamin D3 in the composition of perioodontoprotective agents in the treatment of periodontitis