36,501 research outputs found

    Ricci dark energy in Chern-Simons modified gravity

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    In this work, we have considered the Ricci dark energy model, where the energy density of the universe is proportional to the Ricci scalar curvature, in the dynamic Chern-Simons modified gravity. We show that in this context the evolution of the scale factor is similar to that displayed by the modified Chaplygin gas.Comment: 7 pages; to appear in EPJ

    On FRW Model in Conformal Teleparallel Gravity

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    In this paper we use the conformal teleparallel gravity to study an isotropic and homogeneous Universe which is settled by the FRW metric. We solve the field equations and we obtain the behavior of some cosmological parameters such as scale factor, deceleration parameter and the energy density of the perfect fluid which is the matter field of our model. The field equations, that we called modified Friedmann equations, allow us to define a dark fluid, with dark energy density and dark pressure, responsible for the acceleration in the Universe.Comment: Accepted in EPJ

    Induced pluripotent stem cells, a giant leap for mankind therapeutic applications

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    Induced pluripotent stem cells (iPSC) technology has propelled the field of stem cells biology, providing new cells to explore the molecular mechanisms of pluripotency, cancer biology and aging. A major advantage of human iPSC, compared to the pluripotent embryonic stem cells, is that they can be generated from virtually any embryonic or adult somatic cell type without destruction of human blastocysts. In addition, iPSC can be generated from somatic cells harvested from normal individuals or patients, and used as a cellular tool to unravel mechanisms of human development and to model diseases in a manner not possible before. Besides these fundamental aspects of human biology and physiology that are revealed using iPSC or iPSC-derived cells, these cells hold an immense potential for cell-based therapies, and for the discovery of new or personalized pharmacological treatments for many disorders. Here, we review some of the current challenges and concerns about iPSC technology. We introduce the potential held by iPSC for research and development of novel health-related applications. We briefly present the efforts made by the scientific and clinical communities to create the necessary guidelines and regulations to achieve the highest quality standards in the procedures for iPSC generation, characterization and long-term preservation. Finally, we present some of the audacious and pioneer clinical trials in progress with iPSC-derived cells.info:eu-repo/semantics/publishedVersio

    Analytical characterization of ancient mortars from the archaeological roman site of Pisões (Beja, Portugal)

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    The analytical characterization of mortar samples from the roman archaeological site of Pisões, located in Southern Portugal, were carried out by means of X-ray diffractometry (XRD), thermogravimetry (TGADTA), optical and electron scanning microscopy (SEM-EDS), potentiometry and combustion analysis. The Pisões archaeological complex includes a villa rustica, characterized by well-preserved mosaics and thermal baths, as well as a mill and a mausoleum. Countryside villae epitomized the Romanization of the Iberian Peninsula for over six centuries (2nd century BCE–4th century CE). Nevertheless, most of the Roman villae identified in Portugal have not yet been systematically explored and studied. This study provides valuable data on the construction materials and techniques used in Roman times in the Iberian Peninsula. The careful selection of raw materials and the use of natural and artificial pozzolanic materials can explain the favourable state of conservation, mechanical strength and long-term durability of these mortars

    Quantiles for Fractions and Other Mixed Data

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    This paper studies the estimation of quantile regression for fractional data, focusing on the case where there are mass-points at zero or/and one. More generally, we propose a simple strategy for the estimation of the conditional quantiles of data from mixed distributions, which combines standard results on the estimation of censored and Box-Cox quantile regressions. The implementation of the proposed method is illustrated using a well-known dataset.
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