Isolo : a new concept of privacy

Isolo es un conjunto de cuatro productos interactivos, diseñados por los estudiantes del Grado de Diseño de EINA, que exploran y aplican el concepto “privacidad”. Los proyectos ofrecen diferentes formas de aislamiento respetando los hábitos de los usuarios y recreando atmósferas de intimidad, desde el individuo hasta el colectivo. Los proyectos presentados son: Köllen Eget es un espacio de trabajo adaptado a los nuevos hábitos de trabajo y al uso de las de las nuevas tecnologías. La interactividad del producto permite reorganizar el espacio y generar un ambiente personalizado, adaptándose a cada usuario gracias a la iluminación, la acústica y la presencia de diferentes elementos móviles. Còdol es un separador de espacios que contempla el contraste entre el vacío y la plenitud. Consigue crear un ambiente privado dentro de un entorno interior y concurrido gracias a su estructura envolvente de paneles móviles con propiedades acústicas y tonalidades suaves. Petal es una silla versátil y adaptable al usuario, inspirada en las formas orgánicas de las flores. En cada lateral hay un panel flexible que permite ser regulado en diferentes posiciones y de esta manera convertirlo en un espacio del almacenamiento personalizado acorde con las necesidades del usuario. Kodama es un panel decorativo, que se presenta como una arboleda de influencia oriental coronada por los elementos más distintivos de todo el conjunto: los asientos, que están colocados aleatoriamente por toda la estructura a disposición del usuario.Isolo és un conjunt de quatre productes interactius, dissenyats pels estudiants del Grau de Disseny d’EINA, que exploren i apliquen el concepte “privacitat”. Els projectes ofereixen diferents formes d’aïllament respectant els hàbits dels usuaris i recreant atmosferes d’intimitat, des de l’individu fins al col·lectiu. Els projectes presentats són: Köllen Eget és un espai de treball adaptat als nous hàbits de treball i a l’ús de les noves tecnologies. La interactivitat del producte permet reorganitzar l’espai i generar un ambient personalitzat, adaptant-se a cada usuari a través de la il·luminació, l’acústica i la presència de diferents elements mòbils. Còdol és un separador d’espais que contempla el contrast entre el buit i el ple. Aconsegueix crear un ambient privat dins d’un entorn interior i concorregut gràcies a la seva estructura envoltant de panells mòbils amb propietats acústiques i tonalitats suaus. Petal és una cadira versàtil i adaptable a l’usuari, inspirada en les formes orgàniques de les flors. A cada lateral hi ha un panell flexible que permet ser regulat en diferents posicions i d’aquesta manera convertir-lo en un espai d’emmagatzematge personalitzat d’acord amb les necessitats de l’usuari. Kodama és un panell decoratiu, que es presenta com una arbreda d’influència oriental, coronada pels elements més distintius de tot el conjunt: els seients, que estan disposats aleatòriament per tota l’estructura a disposició de l’usuari.Isolo is a set of four interactive products, designed by students on the EINA Bachelor’s Degree in Design, that explore and apply the concept of “privacy”. The projects offer different forms of isolation, respecting users’ habits and recreating atmospheres of intimacy, from the individual to the group. The projects presented are: Köllen Eget is a workspace adapted to new working habits and the use of new technologies. The interactivity of the product allows users to reorganise their space and create a personalised ambience, adapting to each user through light, sound and the presence of different mobile elements. Còdol is a space divider that considers the contrast between empty and full. It manages to create a private ambience in an interior and busy environment thanks to its structure, surrounded by moveable panels with sound properties and soft tones. Petal is a versatile chair that is adaptable to the user, inspired by the organic shapes of flowers. On each side is a flexible panel that can be regulated in different positions, so turning it into a personalised storage space in line with your needs. Kodama is a decorative panel displayed as an Oriental-influenced woodland crowned by the most distinctive elements of the entire piece: the seats, which are placed at random throughout the whole structure for use by the user

Point-of-care manufacturing: a single university hospital's initial experience

The integration of 3D printing technology in hospitals is evolving toward production models such as point-of-care manufacturing. This study aims to present the results of the integration of 3D printing technology in a manufacturing university hospital.Analysis and interpretation of the data supported by Project PI18/01625 (Ministerio de Ciencia, Innovación y Universidades, Instituto de Salud Carlos III) and European Regional Development Fund (“Una manera de hacer Europa”)

TFG 2016/2017

Amb aquesta publicació, EINA, Centre universitari de Disseny i Art adscrit a la Universitat Autònoma de Barcelona, dóna a conèixer el recull dels Treballs de Fi de Grau presentats durant el curs 2016-2017. Voldríem que un recull com aquest donés una idea més precisa de la tasca que es realitza a EINA per tal de formar nous dissenyadors amb capacitat de respondre professionalment i intel·lectualment a les necessitats i exigències de la nostra societat. El treball formatiu s’orienta a oferir resultats que responguin tant a paràmetres de rigor acadèmic i capacitat d’anàlisi del context com a l’experimentació i la creació de nous llenguatges, tot fomentant el potencial innovador del disseny.Con esta publicación, EINA, Centro universitario de diseño y arte adscrito a la Universidad Autónoma de Barcelona, da a conocer la recopilación de los Trabajos de Fin de Grado presentados durante el curso 2016-2017. Querríamos que una recopilación como ésta diera una idea más precisa del trabajo que se realiza en EINA para formar nuevos diseñadores con capacidad de responder profesional e intelectualmente a las necesidades y exigencias de nuestra sociedad. El trabajo formativo se orienta a ofrecer resultados que respondan tanto a parámetros de rigor académico y capacidad de análisis, como a la experimentación y la creación de nuevos lenguajes, al tiempo que se fomenta el potencial innovador del diseño.With this publication, EINA, University School of Design and Art, affiliated to the Autonomous University of Barcelona, brings to the public eye the Final Degree Projects presented during the 2016-2017 academic year. Our hope is that this volume might offer a more precise idea of the task performed by EINA in training new designers, able to speak both professionally and intellectually to the needs and demands of our society. The educational task is oriented towards results that might respond to the parameters of academic rigour and the capacity for contextual analysis, as well as to considerations of experimentation and the creation of new languages, all the while reinforcing design’s innovative potential

COVID-19 outbreaks in a transmission control scenario: challenges posed by social and leisure activities, and for workers in vulnerable conditions, Spain, early summer 2020

Severe acute respiratory syndrome coronavirus 2 community-wide transmission declined in Spain by early May 2020, being replaced by outbreaks and sporadic cases. From mid-June to 2 August, excluding single household outbreaks, 673 outbreaks were notified nationally, 551 active (>6,200 cases) at the time. More than half of these outbreaks and cases coincided with: (i) social (family/friends’ gatherings or leisure venues) and (ii) occupational (mainly involving workers in vulnerable conditions) settings. Control measures were accordingly applied

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics

22 p.-6 fig.Treadmilling protein filaments perform essential cellular functions by growing from one end while shrinking from the other, driven by nucleotide hydrolysis. Bacterial cell division relies on the primitive tubulin homolog FtsZ, a target for antibiotic discovery that assembles into single treadmilling filaments that hydrolyse GTP at an active site formed upon subunit association. We determined high-resolution filament structures of FtsZ from the pathogen Staphylococcus aureus in complex with different nucleotide analogs and cations, including mimetics of the ground and transition states of catalysis. Together with mutational and biochemical analyses, our structures reveal interactions made by the GTP γ-phosphate and Mg2+ at the subunit interface, a K+ ion stabilizing loop T7 for co-catalysis, new roles of key residues at the active site and a nearby crosstalk area, and rearrangements of a dynamic water shell bridging adjacent subunits upon GTP hydrolysis. We propose a mechanistic model that integrates nucleotide hydrolysis signaling with assembly-associated conformational changes and filament treadmilling. Equivalent assembly mechanisms may apply to more complex tubulin and actin cytomotive filaments that share analogous features with FtsZ.Peer reviewe

Mechanism of FtsZ assembly revealed by filament structures in different nucleotide states

1p.-1 fig.Treadmilling protein filaments perform essential cellular functions by growing from one end while shrinking from the other, driven by nucleotide hydrolysis. Bacterial cell division relies onthe primitive tubulin homolog FtsZ, a target for antibiotic discovery that assembles into single treadmilling filaments that hydrolyse GTP at an active site formed upon subunit association. We determined high-resolution filament structures of FtsZ from the pathogen Staphylococcusaureus in complex with different nucleotide analogues and cations, including mimetics of the ground and transition states of catalysis. Together with mutational and biochemical analyses,our structures reveal interactions made by the GTP -phosphate and Mg2+ at the subunit interface, a K+ ion stabilizing loop T7 for co-catalysis, new roles of key residues at the active site and a nearby crosstalk area, and rearrangements of a dynamic water shell bridging adjacent subunits upon GTP hydrolysis. We propose a mechanistic model that integrates nucleotide hydrolysis signaling with assembly-associated conformational changes and filament treadmilling. Equivalent assembly mechanisms may apply to more complex tubulin and actin cytomotive filaments that share analogous features with FtsZ.Peer reviewe

La Ideología de la maternidad intensiva como eje de la violencia simbólica

El presente informe presenta los resultados, conclusiones y reflexiones de la investigación “La ideología de la maternidad intensiva como eje de la violencia simbólica” financiado por la Unitat d’Igualtat de la Universitat Pompeu Fabra con fondos del Pacto de Estado contra la Violencia de Género y que tiene como objetivos generales identificar situaciones de violencia simbólica de género en el ejercicio de la maternidad y contrastar si esas vivencias son entendidas o no como violencia por las personas afectadas y por sus hijas. Para ello, se han realizado historias de vidas a 6 madres y entrevistas en profundidad a sus hijas jóvenes o adolescentes. El proyecto nace de la convicción de las investigadoras que el trabajo con madres resulta esencial ya que constituye una oportunidad de liberación a partir del reconocimiento de la violencia y la consciencia de la situación como punto de partida del cambio. Por otra parte, decidimos trabajar también con sus hijas con la finalidad de conocer la percepción de ellas en relación a la posible violencia simbólica experimentada por sus madres y la influencia que estos hechos han tenido en sus vidas. De esta manera, entender estas situaciones nos permite aproximarnos a sus imaginarios de maternidad o no maternidad futura. Finalmente, destacamos nuestra firme convicción de potenciar esta línea de investigación y la transferencia de conocimiento trabajando con diferentes modelos de parentalidad, madres y no madres de todas las edades, con hombres, adolescentes, niños y niñas; además de con las personas implicadas en política, educación y salud; con quienes deciden la agenda mediática y el tono del discurso. Trabajar con todas las personas sin distinción de su preferencias de género ni distinción de raza ni clase social; porque un cambio en la visión de la maternidad, por más grande que sea nunca será trascendente si no logra penetrar en todas las capas de la sociedad

Way on : designing from habit to product : catalogue

Way on is a collective initiative developed by the 3rd and 4th year students of the Degree in Design at EINA School of Design and Art of Barcelona, and coordinated by professors Javier Nieto and Oriol Ventura. It is a bridge project between the academic and the professional context. It is held at Salone Satellite - Salone del Mobile Milano where students of product design, interior design, and graphic design have the opportunity to answer the question what design is? raised by the contest. The project is centred on two interrelated lines of work: find solutions to the new habits of society and the relationship between people and the object, and the objects and their surroundings. This initiative is evident in the presentation of six different projects: Nomad, Köllen, Tryk Y-Light, Trote chair, Imagiro and Cut the cube.Way on es una iniciativa colectiva desarrollada por los alumnos de 3º y 4º curso del Grado de Diseño de EINA Centro Universitario de Diseño y Arte de Barcelona, y coordinada por los profesores Javier Nieto y Oriol Ventura. Se trata de un proyecto puente entre el contexto académico y el profesional y es en el Salone Satellite - Salone del Mobile Milano donde los estudiantes de diseño de producto, diseño de interiores y diseño gráfico tienen la oportunidad de responder a la pregunta what design is? planteada por el certamen. El proyecto se articula a través de dos líneas de trabajo interrelacionadas: dar solución a los nuevos hábitos que se presentan en nuestra sociedad y la interacción y relación entre personas y objetos y su entorno. Esta iniciativa se constata en la presentación de seis proyectos diferentes: Nomad, Köllen, Tryk Y-Light, Trote chair, Imagiro y Cut the cube

Conversações desassossegadas: diálogos sobre coleções etnográficas com o povo indígena Ka’apor

Este artigo trata do processo de diálogo sobre coleções etnográficas de objetos Ka’apor e da curadoria compartilhada da exposição “A Festa do Cauim”, atividades promovidas pelo Museu Nacional de Etnologia de Leiden (NME), Holanda, junto ao Museu Paraense Emílio Goeldi (MPEG), Brasil, e o povo indígena Ka’apor da Terra Indígena Alto Turiaçu, localizada no estado de Maranhão, na Amazônia brasileira. É reflexo de uma mudança de filosofia no NME em direção a uma atividade mais inclusiva e colaborativa, como também dos processos de atuação com povos indígenas promovidos no Museu Goeldi e da necessidade política dos Ka’apor de chamar atenção, em nível nacional e internacional, para a defesa de seus direitos territoriais, continuamente ameaçados por atores envolvidos com a exploração ilegal de madeira no seu território. Considerando diferentes enfoques disciplinares, principalmente da antropologia e da museologia, em consonância com o pensamento indígena, assim como com as negociações de interesses e encontro de diversas perspectivas cognitivas e posicionamentos políticos, este artigo, além de documentar e refletir sobre a produção cocriativa de uma exposição etnográfica, procura repensar as dimensões cognitiva, política e ética deste tipo de trabalho com povos indígenas. This article discusses the collaborative research and exhibition project Sharing Collections and Connecting Histories, carried out by the National Museum of Ethnology in Leiden (NME), the Netherlands, the Museu Paraense Emílio Goeldi, Brazil and the Ka’apor indigenous people of the indigenous reserve Alto Turiaçu, Maranhão, Brazil. The collaborative approach that characterized this project reflects a transformation that has been taking place at the NME in Leiden towards a more inclusive and collaborative museological work, and at the Museu Goeldi, which has been promoting collaborative work with indigenous peoples for at least two decades. The project seeks to meet the political needs of the Ka’apor to draw national and international attention to the importance of defending their territorial rights, which are continuously threatened by the illegal exploitation of lumber on their land. This article focuses on the dialogical processes of studying the Ka’apor collections and developing an exhibition. It considers different disciplinary foci — anthropology and museology — in dialogue with indigenous thought, as well as the process of negotiating the interests and the encounters between different cognitive perspectives and political positions. In addition to documenting and reflecting on the co-creative production of an ethnographic exhibition, this article reconsiders the cognitive, political and ethical dimensions of this type of work involving indigenous peoples