Correlação da pressão arterial com o pulso de restrição para prescrição do treinamento com restrição de fluxo sanguíneo

Analisar a correlação entre a pressão arterial e o pulso de restrição para o treinamento com restrição de fluxo sanguíneo (RFS). Foram avaliados 28 homens sedentários e aparentemente saudáveis, com idade entre 22 e 45 anos, não diagnosticados com doenças cardiovasculares, osteomioarticulares, neurológicas ou pulmonares, os quais apresentaram Índice Tornozelo Braquial (ITB) entre 0,9 e 1,3, sem exposição para doenças obstrutivas de membros inferiores, responderam negativamente ao questionário PAR-Q, não fazem uso de medicação contínua ou de uso restrito, não são diabéticos e nem hipertensos e assinaram o Termo de Consentimento Livre Esclarecido (TCLE). Foi verificado os níveis de pressão arterial, ITB, o pulso de restrição, a estatura e o peso dos mesmos. Após a verificação dos testes para analisar a correlação entre a pressão arterial e o pulso de restrição para um treinamento com RFS, podemos identificar que houve uma correlação positiva e moderada para o lado direito, enquanto para o lado esquerdo houve uma correlação positiva e fraca. A pressão arterial e o pulso de restrição da população avaliada apresentaram uma correlação moderada e positiva, porém se faz necessário outros estudos relacionados a outras variáveis que possam influenciar no PRES para um protocolo de treinamento com restrição de fluxo sanguíneo

PREVENÇÃO DE INFECÇÃO PELO VÍRUS SINCICIAL RESPIRATÓRIO EM CRIANÇAS: IMUNIZAÇÃO ATIVA E PASSIVA

This article aims to carry out an analysis of the current medical literature on respiratory syncytial virus, discussing its prevention. Respiratory syncytial virus usually starts like a common cold, with symptoms such as runny nose, low-grade fever and cough. The disease can progress to shortness of breath, caused by bronchiolitis, an inflammatory condition of the bronchioles, which are smaller branches of the channels that transport air to the lungs — the bronchi. There are several vaccines under development for respiratory syncytial virus, using different technologies. In May 2023, the United States approved the world's first vaccine against the disease, suitable for the elderly.Este artigo tem por objetivo realizar uma análise da literatura médica vigente sobre o vírus sincicial respiratório, discutindo sobre a prevenção do mesmo. O vírus sincicial respiratório geralmente inicia-se como um resfriado comum, com sintomas como coriza, febre baixa e tosse. A doença pode evoluir para falta de ar, causada por bronquiolite, uma condição inflamatória dos bronquíolos, que são ramificações menores dos canais que transportam o ar para os pulmões — os brônquios. Há várias vacinas em desenvolvimento para o vírus sincicial respiratório, de diferentes tecnologias. Em maio de 2023 os Estados Unidos aprovaram a primeira vacina do mundo contra a doença, indicada para idosos

Neurostimulation Combined With Cognitive Intervention in Alzheimer’s Disease (NeuroAD): Study Protocol of Double-Blind, Randomized, Factorial Clinical Trial

Despite advances in the treatment of Alzheimer’s disease (AD), there is currently no prospect of a cure, and evidence shows that multifactorial interventions can benefit patients. A promising therapeutic alternative is the use of transcranial direct current stimulation (tDCS) simultaneously with cognitive intervention. The combination of these non-pharmacological techniques is apparently a safe and accessible approach. This study protocol aims to compare the efficacy of tDCS and cognitive intervention in a double-blind, randomized and factorial clinical trial. One hundred participants diagnosed with mild-stage AD will be randomized to receive both tDCS and cognitive intervention, tDCS, cognitive intervention, or placebo. The treatment will last 8 weeks, with a 12-month follow-up. The primary outcome will be the improvement of global cognitive functions, evaluated by the AD Assessment Scale, cognitive subscale (ADAS-Cog). The secondary outcomes will include measures of functional, affective, and behavioral components, as well as a neurophysiological marker (Brain-derived neurotrophic factor, BDNF). This study will enable us to assess, both in the short and long term, whether tDCS is more effective than the placebo and to examine the effects of combined therapy (tDCS and cognitive intervention) and isolated treatments (tDCS vs. cognitive intervention) on patients with AD.Clinical Trial Registration: www.ClinicalTrials.gov, identifier NCT02772185—May 5, 2016

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

Gestão pública II: relatos, pesquisas, experiências e visão de trabalho.

Coletânea de trabalhos publicados e premiados no II Seminário de Gestão Pública da UFRA e na 1ª edição do Prêmio Novos Ventos de Gestão Pública, sob a responsabilidade da Pró-Reitoria de Gestão de Pessoas (PROGEP).UNIVERSIDADE FEDERAL RURAL DA AMAZÔNIAEste livro, na forma de coletânea, se constituiu em um processo mais amplo de reflexão sobre a gestão pública dentro da Universidade. Aqui, partimos para uma importante reflexão, a partir do processo de sistematizar experiências, relatos de experiência, e pesquisas, sobre a Universidade Pública e sua relação com as pessoas e as ciências. Em especial, o capítulo 1, a partir da coletânea dos trabalhos apresentados no II Seminário de Gestão Pública, diferencia-se dos trabalhos submetidos para a primeira edição. As experiências destacadas para este livro reforçam a identidade e missão da UFRA, como os resultados dos trabalhos “OS CAMINHOS DA MERENDA ESCOLAR: análise da logística na cadeia de suprimentos do município de Tomé-Açu” e “ANÁLISE QVT NA GESTÃO DE UMA EMPRESA PRODUTORA DE DENDÊ EM TOMÉ-AÇU/PA”, e que também agregam valor a gestores e equipes de trabalho quando promovem a discussão de temas relacionados ao dia-a-dia do trabalho, tais como: QUALIDADE DE VIDA NO TRABALHO e GESTÃO ESTRATÉGICA DE PESSOAS NO SETOR PÚBLICO. Nesse sentido, servidores e pesquisadores cumprem a função de embasar inúmeras discussões que vêm sendo travadas pelas Instituições Públicas sobre qualidade de vida, inclusão, garantia de direitos, melhoria de procedimentos, dentre outros. O capítulo II, enquanto coletânea das experiências de trabalho indicada para premiação, é um momento riquíssimo de se perceber a quantidade e a qualidade de ações planejadas, organizadas e realizadas por servidores públicos. Em tempos que algumas práticas do serviço público não são bem vistas, reforça-se aqui que alguns dos relatos foram concebidos em meio a falta de recursos financeiros e estruturais, mas que não impediram os proponentes de seguir em frente. Mais do que isso, o reconhecimento dos beneficiários e usuários faz com que reforcemos a necessidade de fortalecer ações que agregam inúmeros valores a vida laboral dos servidores públicos e a própria Universidade Pública.This book, in the form of a collection, constituted a broader process of reflection on public management within the University. Here, we start an important reflection, based on the process of systematizing experiences, experience reports, and research, about the Public University and its relationship with people and the sciences. In particular, chapter 1, from the collection of works presented at the II Seminar on Public Management, differs from the works submitted for the first edition. The experiences highlighted for this book reinforce UFRA's identity and mission, such as the results of the work “THE PATHS OF SCHOOL BREAKFAST: analysis of logistics in the supply chain in the municipality of Tomé-Açu” and “QVT ANALYSIS IN THE MANAGEMENT OF A PRODUCING COMPANY OF DENDÊ IN TOMÉ-AÇU / PA ”, and which also add value to managers and work teams when promoting the discussion of topics related to day-to-day work, such as: QUALITY OF LIFE AT WORK and STRATEGIC PEOPLE MANAGEMENT IN THE PUBLIC SECTOR. In this sense, civil servants and researchers fulfill the function of supporting numerous discussions that have been held by Public Institutions on quality of life, inclusion, guarantee of rights, improvement of procedures, among others. Chapter II, as a collection of work experiences indicated for awards, is a very rich moment to realize the quantity and quality of actions planned, organized and carried out by public servants. In times when some public service practices are not well regarded, it is reinforced here that some of the reports were conceived amid a lack of financial and structural resources, but that did not prevent proponents from moving forward. More than that, the recognition of beneficiaries and users makes us reinforce the need to strengthen actions that add innumerable values ​​to the working life of public servants and the Public University itself

Homeostatic model assessment of adiponectin (HOMA-Adiponectin) as a surrogate measure of insulin resistance in adolescents: comparison with the hyperglycaemic clamp and homeostatic model assessment of insulin resistance

Background Studies on adults have reported inverse association between the homeostatic model assessment (HOMA) of adiponectin (HOMA-Adiponectin) and the insulin resistance assessed by the glucose clamp technique. To our knowledge, in the pediatric population this association has not been previously investigated. Objectives To evaluate the association between the HOMA-Adiponectin and the insulin resistance assessed by the glucose clamp technique in adolescents, and to compare the accuracy of HOMA-Adiponectin and HOMA-insulin resistance (HOMA-IR) for identifying insulin resistance. Methods This was a cross-sectional study of 56 adolescents (aged 1018 years). Insulin resistance was assessed using the HOMA-IR, HOMA-Adiponectin and the hyperglycaemic clamp technique. The clamp-derived insulin sensitivity index, HOMA-Adiponectin, and HOMA-IR were log-transformed to get closer to a normal distribution before analysis. Results In the multivariable linear regression analysis controlling for sex and Tanner stage, HOMA-Adiponectin was inversely associated with the clamp-derived insulin sensitivity index (unstandardized coefficient [B] = -0.441; P < 0.001). After additional adjustment for waist circumference-to-height ratio, this association remained significant (B = -0.349; P = < 0.001). Similar results were observed when HOMA-IR replaced HOMA-Adiponectin in the model (B = -1.049 and B = -0.968 after additional adjustment for waist circumference-to-height ratio); all P < 0.001. The area under the receiver operating characteristic curve for predicting insulin resistance was 0.712 (P = 0.02) for HOMA-Adiponectin and 0.859 (P < 0.0001) HOMA-IR. Conclusions The HOMA-Adiponectin was independently associated with insulin resistance and exhibited a good discriminatory power for predicting it. However, it did not show superiority over HOMA-IR in the diagnostic accuracy143CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP563664/2010-02013/21476-