Diffusion of scientific credits and the ranking of scientists

Recently, the abundance of digital data enabled the implementation of graph based ranking algorithms that provide system level analysis for ranking publications and authors. Here we take advantage of the entire Physical Review publication archive (1893-2006) to construct authors' networks where weighted edges, as measured from opportunely normalized citation counts, define a proxy for the mechanism of scientific credit transfer. On this network we define a ranking method based on a diffusion algorithm that mimics the spreading of scientific credits on the network. We compare the results obtained with our algorithm with those obtained by local measures such as the citation count and provide a statistical analysis of the assignment of major career awards in the area of Physics. A web site where the algorithm is made available to perform customized rank analysis can be found at the address http://www.physauthorsrank.orgComment: Revised version. 11 pages, 10 figures, 1 table. The portal to compute the rankings of scientists is at http://www.physauthorsrank.or

Community Group-Based Models of Medication Delivery: Applicability to Cardiovascular Diseases.

The rising global burden of chronic non-communicable diseases (NCDs) has put a strain on healthcare systems globally, especially in low- and middle-income countries, which have seen disproportionate mortality rates due to non-communicable diseases. These deaths are in part due to challenges with medication adherence, which are compounded by lack of access to medication and weak community support systems. This paper aims to propose a potential solution using models of service delivery in HIV/AIDS, given the many similarities between NCD and HIV/AIDS. Models that have been particularly effective in HIV/AIDS are the community-based peer-support medication delivery groups: medication adherence clubs and community antiretroviral therapy (ART) groups. The positive outcomes from these models, including improved medication adherence and patient satisfaction, provide evidence for their potential success when applied to non-communicable diseases, particularly hypertension and cardiovascular disease

Critical Droplets and Phase Transitions in Two Dimensions

In two space dimensions, the percolation point of the pure-site clusters of the Ising model coincides with the critical point T_c of the thermal transition and the percolation exponents belong to a special universality class. By introducing a bond probability p_B<1, the corresponding site-bond clusters keep on percolating at T_c and the exponents do not change, until p_B=p_CK=1-exp(-2J/kT): for this special expression of the bond weight the critical percolation exponents switch to the 2D Ising universality class. We show here that the result is valid for a wide class of bidimensional models with a continuous magnetization transition: there is a critical bond probability p_c such that, for any p_B>=p_c, the onset of percolation of the site-bond clusters coincides with the critical point of the thermal transition. The percolation exponents are the same for p_c<p_B<=1 but, for p_B=p_c, they suddenly change to the thermal exponents, so that the corresponding clusters are critical droplets of the phase transition. Our result is based on Monte Carlo simulations of various systems near criticality.Comment: Final version for publication, minor changes, figures adde

Hydrodynamics near the QCD Phase Transition: Looking for the Longest-Lived Fireball

We propose a new strategy for the experimental search of the QCD phase transition in heavy ion collisions: One may tune collision energy around the point where the lifetime of the fireball is expected to be longest. We demonstrate that the hydrodynamic evolution of excited nuclear matter does change dramatically as the initial energy density goes through the "softest point" (where the pressure to energy density ratio reaches its minimum). For our choice of equation of state, this corresponds to epsilon_i approx. = 1.5 GeV/fm^3 and collision energy E_lab/A approx. = 30 GeV (for Au+Au). Various observables seem to show distinct changes near the softest point.Comment: 7 pages, 3 Postscript figures (tar compressed and uuencoded) submitte

Hybrid 3D structure of poly(d,l-lactic acid) loaded with chitosan/chondroitin sulfate nanoparticles to be used as carriers for biomacromolecules in tissue engineering

In the tissue engineering (TE) field, the concept of producing multifunctional scaffolds, capable not only of acting as templates for cell transplantation but also of delivering bioactive agents in a controlled manner, is an emerging strategy aimed to enhance tissue regeneration. In this work, a complex hybrid release system consisting in a three-dimensional (3D) structure based on poly(d,l-lactic acid) (PDLLA) impregnated with chitosan/chondroitin sulfate nanoparticles (NPs) was developed. The scaffolds were prepared by supercritical fluid foaming at 200 bar and 35 "C, and were then characterized by scanning electron microscopy (SEM) and micro-CT. SEM also allowed to assess the distribution of the NPs within the structure, showing that the particles could be found in different areas of the scaffold, indicating a homogeneous distribution within the 3D structure. Water uptake and weight loss measurements were also carried out and the results obtained demonstrated that weight loss was not significantly enhanced although the entrapment of the NPs in the 3D structure clearly enhances the swelling of the structure. Moreover, the hybrid porous biomaterial displayed adequate mechanical properties for cell adhesion and support. The possibility of using this scaffold as a multifunctional material was further evaluated by the incorporation of a model protein, bovine serum albumin (BSA), either directly into the PDLLA foam or in the NPs that were eventually included in the scaffold. The obtained results show that it is possible to achieve different release kinetics, suggesting that this system is a promising candidate for dual protein delivery system for TE applications

Searching for supergiant fast X-ray transients with Swift

Supergiant fast X-ray transients (SFXTs) are high mass X-ray binaries (HMXBs) hosting a neutron star and an OB supergiant companion. We examine the available Swift data, as well as other new or archival/serendipitous data, on three sources: IGR J17407-2808, 2XMM J185114.3-000004, and IGR J18175-2419, whose X-ray characteristics qualify them as candidate SFXT, in order to explore their properties and test whether they are consistent with an SFXT nature. As IGR J17407-2808 and 2XMM J185114.3-000004 triggered the Burst Alert Telescope on board Swift, the Swift data allow us to provide their first arcsecond localisations, leading to an unequivocal identification of the source CXOU J174042.0-280724 as the soft X-ray counterpart of IGR J17407-2808, as well as their first broadband spectra, which can be fit with models generally describing accreting neutron stars in HMXBs. While still lacking optical spectroscopy to assess the spectral type of the companion, we propose 2XMM J185114.3-000004 as a very strong SFXT candidate. The nature of IGR J17407-2808 remains, instead, more uncertain. Its broad band properties cannot exclude that the emission originates from either a HMXB (and in that case, a SFXT) or, more likely, a low mass X-ray binary. Finally, based on the deep non-detection in our XRT monitoring campaign and a careful reanalysis of the original Integral data in which the discovery of the source was first reported, we show that IGR J18175-2419 is likely a spurious detection.Comment: Accepted for publication in Astronomy and Astrophysics. 12 pages, 11 figures, 6 table

The peculiar 2011 outburst of the black hole candidate IGR J17091−3624, a GRS 1915+105-like source?

We report on the long-term monitoring campaign of the black hole candidate IGR J17091−3624 performed with INTEGRAL and Swift during the peculiar outburst started on 2011 January. We have studied the two-month spectral evolution of the source in detail. Unlike the previous outbursts, the initial transition from the hard to the soft state in 2011 was not followed by the standard spectral evolution expected for a transient black hole binary. IGR J17091−3624 showed pseudo-periodic flare-like events in the light curve, closely resembling those observed from GRS 1915+105. We find evidence that these phenomena are due to the same physical instability process ascribed to GRS 1915+105. Finally, we speculate that the faintness of IGR J17091−3624 could be not only due to the high distance of the source but also due to the high inclination angle of the syste

The first outburst of the black hole candidate MAXI J1836-194 observed by INTEGRAL, Swift, and RXTE

MAXI J1836-194 is a transient black-hole candidate discovered in outburst by MAXI on 30 August 2011. We report on the available INTEGRAL, Swift, and RXTE observations performed in the direction of the source during this event before 55 864 MJD. Combining the broad band (0.6-200 keV) spectral and timing information obtained from these data with the results of radio observations, we show that the event displayed by MAXI J1836-194 is another example of "failed" outburst. During the first ~20 days after the onset of the event, the source underwent a transition from the canonical low/hard to the hard intermediate state, while reaching the highest X-ray flux. In the ~40 days following the peak of the outburst, the source displayed a progressive spectral hardening and a decrease of the X-ray flux, thus it entered again the low/hard state and began its return to quiescence.Comment: Accepted for A&A Letters on 22 Dec. 201

Protease and hemicellulase assisted extraction of dietary fiber from wastes of Cynara cardunculus

6057-6075The action of protease and hemicellulase for the extraction of fractions enriched in soluble fiber from bracts and stems of Cynara cardunculus was evaluated. Using a two-factor simplex design comprising protease amounts of 0-200 ?L and hemicellulase amounts of 0-200 mg for 5 g of material, we explored the effect of a 5 h enzymatic treatment at 40 °C on the chemical composition and yield of the fractions isolated. The fractions contained inulin and pectin. In general, the protein, inulin, and polyphenol contents and also the yields were higher for fractions obtained from stems. The most marked effects were observed when enzymes were used at higher concentrations, especially for hemicellulase. The inclusion of a pre-heating step increased the yield and the inulin content for fractions isolated from bracts and stems and decreased the protein and polyphenol contents, and the galacturonic acid for bracts. These fractions, in general, contained the polyphenolic compounds monocaffeoylquinic acid, apigenin, and pinoresinol