Microscopic cluster model for the description of (18O,16O) two-neutron transfer reactions

Excitation energy spectra and absolute cross-section angular distributions were measured for the 13C(18O,16O)15C two-neutron transfer reaction at 84 MeV incident energy. Exact finite-range coupled reaction channel calculations are used to analyse the data considering both the direct two-neutron transfer and the two-step sequential mechanism. For the direct calculations, two approaches are discussed: The extreme cluster and the newly introduced microscopic cluster. The latter makes use of spectroscopic amplitudes in the centre-of-mass reference frame, derived from shell-model calculations. The results describe well the experimental cross sections

Microscopic cluster model for the description of new experimental results on the C 13 (O 18, O 16) C 15 two-neutron transfer at 84 MeV incident energy

The C13(O18,O16)C15 reaction is studied at 84 MeV incident energy. Excitation energy spectra and absolute cross-section angular distributions for the strongest transitions are measured with good energy and angular resolutions. Strong selectivity for two-neutron configurations in the states of the residual nucleus is found. The measured cross-section angular distributions are analyzed by exact finite-range coupled reaction channel calculations. The two-particle wave functions are extracted using the extreme cluster and the independent coordinate scheme with shell-model derived coupling strengths. A new approach also is introduced, the microscopic cluster, in which the spectroscopic amplitudes in the center-of-mass reference frame are derived from shell-model calculations using the Moshinsky transformation brackets. This new model is able to describe well the experimental cross section and to highlight cluster configurations in the involved wave functions

LOW COST TECHNIQUES FOR THE DIGITAL SURVEY OF A MINOAN ARCHITECTURE IN THE ARCHEOLOGICAL SITE OF PHAISTOS (CRETE)

Abstract. The paper shows the results of an experimentation on the use of low cost tools such as action cameras for the photogrammetric surveying of relevant archaeological sites characterized by the presence of narrow and complex rooms. The archaeological site chosen for this experimentation is the South-Western Quarter, also known as Quartiere Levi, of the Minoan Palace of Phaistos (Crete), one of only two cases of buildings surviving up to the third floor in the Aegean world. The research foresaw the setting up of a pipeline aimed at obtaining a complete scaled, photorealistic and navigable 3D model, with a considerable economy in terms of work time and number of photographs. For this purpose, many efforts have been paid on solving all the issues related to the complexity of the site and on comparing the performances of traditional (Canon EOS 70D) and action (GoPro Black Hero 6) cameras as well as of two of the current most used software in the field

Hand Held 3D Scanning for Cultural Heritage: Experimenting Low Cost Structure Sensor Scan.

In the last years 3D scanning has become an important resource in many fields, in particular it has played a key role in study and preservation of Cultural Heritage. Moreover today, thanks to the miniaturization of electronic components, it has been possible produce a new category of 3D scanners, also known as handheld scanners. Handheld scanners combine a relatively low cost with the advantage of the portability. The aim of this chapter is two-fold: first, a survey about the most recent 3D handheld scanners is presented. As second, a study about the possibility to employ the handheld scanners in the field of Cultural Heritage is conducted. In this investigation, a doorway of the Benedictine Monastery of Catania, has been used as study case for a comparison between stationary Time of Flight scanner, photogrammetry-based 3D reconstruction and handheld scanning. The study is completed by an evaluation of the meshes quality obtained with the three different kinds of technology and a 3D modeling reproduction of the case-study doorway

THE VIRTUAL BATCAVE: A PROJECT FOR THE SAFEGUARD OF A UNESCO WHL FRAGILE ECOSYSTEM

Abstract. This abstract illustrates an interdisciplinary research project which focuses on the study, conservation and enhancement, through 3D digitization and virtual fruition, of an asset of great naturalistic, historical and ethnoanthropological value: Grotta dei Pipistrelli of Pantalica Nature Reserve (Sortino, SR). The cave (located in the Calcinara necropolis) is characterized by a great beauty as well as by a high cultural relevance and a remarkable scientific importance. In 2005, it awarded the UNESCO World Heritage title for its high historic, archaeological and speleological profile. Despite the site is being studied by specialists in chiropterofauna, nowadays there is not a comprehensive and reliable documentation of the plano-altimetric morphology of the cave, able to constitute a 3D database of essential information (e.g. morphological, geological, textural and wildlife information) for current and future studies, and to preserve the memory of this fragile ecosystem. The process of 3D digitization aims to create a model of the cave that allows us to enjoy this place, to explore it and to closely understand it in order to limit the anthropic pressure caused by visitors on the real site. Consequently, it is proposed the creation of a virtual environment, as a reproduction of the real one, which can be enjoyed by all categories of users.</p

STUDY OF THE O-18+Ni-64 TWO-NEUTRON TRANSFER REACTION AT 84 MeV BY MAGNEX

A study of the two-neutron transfer reaction of the O-18 + Ni-64 system at 84 MeV incident energy to the ground and first 2(+) excited state of the residual Ni-66 nucleus is presented. The experiment was performed at the INFN-LNS (Italy) by using the large acceptance MAGNEX spectrometer. Theoretical models are used in order to disentangle the competition between long-range and short-range correlations

Long-range versus short-range correlations in the two-neutron transfer reaction Ni 64 (O 18, O 16) Ni 66

Recently, various two-neutron transfer studies using the (18O,16O) reaction were performed with a large success. This was achieved because of a combined use of the microscopic quantum description of the reaction mechanism and of the nuclear structure. In the present work we use this methodology to study the two-neutron transfer reaction of the 18O+64Ni system at 84 MeV incident energy, to the ground and first 2+ excited state of the residual 66Ni nucleus. All the experimental data were measured by the large acceptance MAGNEX spectrometer at the Instituto Nazionale di Fisica Nucleare \u2013Laboratori Nazionali del Sud (Italy). We have performed exact finite range cross section calculations using the coupled channel Born approximation (CCBA) and coupled reaction channel (CRC) method for the sequential and direct two-neutron transfers, respectively. Moreover, this is the first time that the formalism of the microscopic interaction boson model (IBM-2) was applied to a two-neutron transfer reaction. From our results we conclude that for two-neutron transfer to the ground state of 66Ni, the direct transfer is the dominant reaction mechanism, whereas for the transfer to the first excited state of 66Ni, the sequential process dominates. A competition between long-range and short-range correlations is discussed, in particular, how the use of two different models (Shell model and IBM's) help to disentangle long- and short-range correlations

DNA methylase modifications and other linezolid resistance mutations in coagulase-negative staphylococci in Italy

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Weekly administration of vincristine, cyclophosphamide, mitoxantrone and bleomycin (VEMB) in the treatment of elderly aggressive non Hodgkin's lymphoma

Background and Objective. Aim of the study was to assess the efficacy of VEMB, a short-lasting therapeutic regimen (50 days) which alternates two myelotoxic drugs (cyclophosphamide and mitoxantrone) every week with two less hematologically toxic drugs (vincristine and bleomycin) in the treatment of aggressive NHL in the elderly (over 70). Design and Methods. Between November 1994 and March 1996, 37 patients aged more than 70 years, with highly or moderately malignant NHL (according to the Working Formulation) have been enrolled into the study. The stage of the disease ranged between II and IV according to Ann Arbor. Mean age was 77 years; 14 patients (38%) had stage IV; 19 patients (51%) had LDH higher than normal; 26 patients (70%) had extranodal and 9 patients (24%) had bulky disease at time of diagnosis. Results. Sixty-two percent of patients achieved a complete and 22% a partial remission. Non-responders amounted to 5%. Four patients (11%) died during the therapy; Nine patients (24%) experienced grade III-IV neutropenia. The most frequently observed event was mild neurotoxicity (43% of cases). The overall survival rate at 30 months was 55%. DFS at 24 months was 66%. Interpretation and Conclusions. VEMB is a therapeutic regimen whose efficacy is comparable to that of the other derived MACOP-B therapeutic regimens used in the elderly NHL. It has proved to have a good feasibility, though the number of toxic deaths should not be neglected

In vitro skin permeation of idebenone from lipid nanoparticles containing chemical penetration enhancers

Lipid nanoparticles (LNPs) have been proposed as carriers for drug skin delivery and targeting. As LNPs effectiveness could be increased by the addition of chemical penetration enhancers (PE), in this work, the feasibility of incorporating PE into LNPs to improve idebenone (IDE) targeting to the skin was investigated. LNPs loading IDE 0.7% w/w were prepared using hydrophilic (propylene glycol, PG, 10% w/w or N-methylpyrrolidone, NMP, 10% w/w) and/or lipophilic PE (oleic acid, OA, 1% w/w; isopropyl myristate, IPM, 3.5% w/w; a mixture of 0.5% w/w OA and 2.5% w/w IPM). All LNPs showed small sizes (&lt;60 nm), low polydispersity index and good stability. According to the obtained results, IDE release from LNPs was not the rate-limiting step in IDE skin penetration. No IDE permeation was observed through excised pigskin from all LNPs, while the greatest increase of IDE penetration into the different skin layers was obtained using the mixture OA/IPM. The antioxidant activity of IDE-loaded LNPs, determined by the oxygen radical absorbance capacity assay, was greater than that of free IDE. These results suggest that the use of suitable PE as LNPs components could be regarded as a promising strategy to improve drug targeting to the skin