Un simposio y tres agones: una lectura del Banquete de Platón

Entre los diálogos de Platón, el Banquete es probablemente el más seductor y el más logrado desde el punto de vista literario, por su estilo, estructura, personajes y técnicas dramáticas y retóricas. Obra de extraordinaria riqueza, tanto por la pintura de los personajes, los temas que aborda y el modo en que los entrelaza, por momentos puede resultar desconcertante para un lector no entrenado. Platón enlaza con su habitual maestría los componentes filosóficos y los dramáticos, con diferencias de tono y de ritmo. Los personajes –todos ellos, salvo Sócrates, oradores no filósofos– están insertos en el contexto más adecuado y cuidadosamente construidos para representar el papel que a cada uno de ellos le corresponde y pronunciar el encomio sobre el amor que a cada uno le cuadra.O Banquete tem sido lido e interpretado desde diferentes perspectivas. Neste trabalho se propõe uma leitura do diálogo desde a perspectiva do agón literário, segundo a qual a ação principal consiste, mais que numa série de cinco contribuições individuais, que assumem o caráter de “encômios epidíticos”, cujo único propósito seria apresentar tipos de indivíduos e de estilos para confrontá-los com Sócrates, em três agónes (Fedro vs. Pausâ- nias, Erixímaco vs. Aristófanes e Agatão vs. Sócrates), separados por dois interlúdios cômicos. Ainda que os personagens não pareçam ter a intenção de cooperar, porém de competir entre si, Platão constrói o diálogo para mostrar que, apesar de seus respectivos autores, os discursos acabam cooperando para apresentar o que em definitivo é o grande agón: o agón entre a filosofia e outras artes ou técnicas.Le banquet a été lu et interprété à partir de différents points de vue. Dans cette étude, je me propose d’offrir une lecture du dialogue du point de vue de l’agôn littéraire, lecture d’après laquelle l’action principale, plutôt que consister en une série de cinq contributions individuelles – cinq «éloges épidictiques» dont le seul but serait de présenter des types d’individus et de styles pour les confronter avec Socrate – est constituée par trois agôns (Phèdre vs. Pausanias, Éryximaque vs. Aristophane, et Agathon vs. Socrate), séparés par deux intermèdes comiques. Bien que les personnages ne semblent pas avoir l’intention de coopérer, mais de se mettre en concurrence, Platon construit le dialogue pour montrer que, en dépit de leurs auteurs, les discours coopèrent juste dans le but de présenter ce qui est finalement le grand agôn: l’agôn entre la philosophie et d’autres arts et techniques.Fil: Santa Cruz, Maria Isabel. Universidad de Buenos Aires; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

Naturaleza y arte en Plotino: forma y belleza

Tras unas observaciones generales sobre el proceder exegético de Plotino y su concepción de la realidad, se procura mostrar cómo la naturaleza, función inferior del alma, produce espontáneamente, por su sola contemplación, gracias a los principios formales que recibe del alma superior y que proyecta sobre la materia para dar forma y vida a lo sensible. Plotino rechaza el modelo técnico como explicación de la producción natural y critica el arte mimético: pero naturaleza y arte parten ambas de un principio racional. Si en la naturaleza ese principio es interno, en el arte se requiere la intermediación del artífice, que lo concibe en su mente. La belleza es siempre inteligible y los productos de la naturaleza y los del arte son bellos, no por su materialidad, sino por la forma que se impone sobre el sustrato.After some general remarks on Plotinus's exegesis and his conception of reality, this article aims to show how nature, the lower function of the soul, produces spontaneously by contemplation, in virtue of the formal principles that it receives from the higher soul and projects on matter to give form and life to the sensible. Plotinus rejects the technical model as an explanation of natural production and criticizes mimetic art; but both nature and real art start from a rational principle. While this principle is in nature internal, in art it is external and requires the intermediation of the artist, who conceives it in his mind. Beauty is always intelligible and the products of nature and those of art are beautiful, not because of their materiality, but because of the form that is imposed on the substrate.Fil: Santa Cruz, Maria Isabel. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Instituto de Filosofía "Dr. Alejandro Korn"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

Sobre la categoría de relativos en Platón y Aristóteles

Uno de los textos de lectura y comentario casi obligados en las escuelas medio y neoplatónicas fue el tratado Categorías de Aristóteles. No contamos con evidencia de que Platón haya desarrollado algo tan elaborado como las categorías aristotélicas, pero ya la Antigüedad encontró en los diálogos un anticipo de ellas. Los textos y testimonios de los que disponemos permiten sostener que Platón ya tenía en claro la distinción entre algunas de lo que Aristóteles llamó luego “categorías”, al menos las de sustancia, cualidad, cantidad y relativos. En el artículo se presta atención a algunos aspectos del tratamiento aristotélico de la categoría de relativos y se trata de mostrar cómo hay en él elementos ya presentes en los diálogos de Platón.Aristotle’s Categories was one of the texts read and commented in Medioplatonist and Neoplatonic schools. We have no evidence that Plato developed something as elaborate as the Aristotelian categories, but the Ancients found in the dialogues an advance of them. The available texts and testimonies allowed us to sustain that Plato already made a clear distinction between some of what Aristotle called “categories”, at least substance, quality, quantity and relatives. The article pays attention to some aspects of the Aristotelian treatment of the category of relatives and tries to show that in that treatment there are different elements already present in the dialogues of Plato.Fil: Santa Cruz, Maria Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires; Argentin

Naturaleza y arte en Plotino: forma y belleza

Tras unas observaciones generales sobre el proceder exegético de Plotino y su concepción de la realidad, se procura mostrar cómo la naturaleza, función inferior del alma, produce espontáneamente, por su sola contemplación, gracias a los principios formales que recibe del alma superior y que proyecta sobre la materia para dar forma y vida a lo sensible. Plotino rechaza el modelo técnico como explicación de la producción natural y critica el arte mimético: pero naturaleza y arte parten ambas de un principio racional. Si en la naturaleza ese principio es interno, en el arte se requiere la intermediación del artífice, que lo concibe en su mente. La belleza es siempre inteligible y los productos de la naturaleza y los del arte son bellos, no por su materialidad, sino por la forma que se impone sobre el sustrato.After some general remarks on Plotinus's exegesis and his conception of reality, this article aims to show how nature, the lower function of the soul, produces spontaneously by contemplation, in virtue of the formal principles that it receives from the higher soul and projects on matter to give form and life to the sensible. Plotinus rejects the technical model as an explanation of natural production and criticizes mimetic art; but both nature and real art start from a rational principle. While this principle is in nature internal, in art it is external and requires the intermediation of the artist, who conceives it in his mind. Beauty is always intelligible and the products of nature and those of art are beautiful, not because of their materiality, but because of the form that is imposed on the substrate.Fil: Santa Cruz, Maria Isabel. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Instituto de Filosofía "Dr. Alejandro Korn"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

Sobre el concepto de semejanza: Plotino, Enéadas I 2

El tratado I 6, número 19 en el orden cronológico, tiene por fin explicar la definición de la virtud como semejanza con Dios. Plotino considera que las virtudes cívicas, tales como Platón las presenta no pueden estar realizadas en Dios, porque se trata de virtudes inferiores. En el capítulo 2, para analizar las virtudes por las que se deviene semejante a Dios, se trata de hallar el elemento común que en el hombre es imagen y en Dios paradigma. Para ello Plotino establece una distinción entre dos tipos de semejanza: aquella que requiere la presencia de un elemento idéntico entre las cosas que se asemejan y aquella otra que exige un elemento diferente entre ellas. En este trabajo se intenta mostrar cómo esta distinción claramente trazada entre dos tipos de semejanza permite disolver una serie de problemas que se presentan en los diálogos platónicos (entre ellos el “segundo tercer hombre” de Parménides, esto es, las dificultades que encierra concebir la participación como una relación de semejanza entre copia y modelo).The object of the treatise I 6 -19 in Porphyry’s chronological order- is to determine in what precise sense virtue consists in the likeness to God (homoíosis theô). Plotinus asserts that God cannot possess the civic virtues, as presented by Plato in Republic, because they are lower virtues. In Chapter 2, in order to analyse the virtues through which we become godlike, it is neccesary to discover the common element which, being image in men, exists in God as an archetype. Plotinus remarks that there are two kinds of likeness: one requires that there should be something the same in the things which are alike, the other requires somethig different between them. The present article aims to show how that clear distinction between two kinds of likeness allows to solve some problems displayed in Platonic dialogues (among them the Parmenides’ « second third man », i. e., the difficulties which follow from presenting participation as a relation of likeness between copy and model).Fil: Santa Cruz, Maria Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires; Argentin

Distributive justice and due measure in Plato

En este artículo se examina la caracterización de la justicia que ofrece Platón en las Leyes, tanto de la justicia distributiva entendida como igualdad proporcional, como de la justicia correctiva, anticipando los desarrollos de Aristóteles en la Ética Nicomaquea. Se pretende poner de manifiesto en qué medida la concepción de la justicia en las Leyes puede acercarse a la presentada en la República, y se sostiene que el criterio último que, de algún modo, las unifica es la noción de medida y, más precisamente, de justa medida. Sobre el final del artículo, se discute hasta qué punto es posible atribuir a Platón, como lo han hecho algunos autores, una defensa del "derecho natural".This article examines the characterization of justice that Plato offers in the Laws, both of the distributive justice understood as proportional equality, and of the corrective justice, anticipating the developments of Aristotle in his Nichomachean Ethics. The aim is to show to what extent the conception of justice in the Laws is not so far from that presented in the Republic. The main point is to bring out that the ultimate criterion that, in some way, unifies the different presentations of justice is the notion of measure and, more precisely, of due measure. At the end of the article, it is discussed to what extent it is possible to attribute to Plato, as some authors have done, a defense of "natural right".Fil: Santa Cruz, Maria Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Centro de Filosofía Antigua; Argentin

Sobre la categoría de relativos en Platón y Aristóteles

Uno de los textos de lectura y comentario casi obligados en las escuelas medio y neoplatónicas fue el tratado Categorías de Aristóteles. No contamos con evidencia de que Platón haya desarrollado algo tan elaborado como las categorías aristotélicas, pero ya la Antigüedad encontró en los diálogos un anticipo de ellas. Los textos y testimonios de los que disponemos permiten sostener que Platón ya tenía en claro la distinción entre algunas de lo que Aristóteles llamó luego “categorías”, al menos las de sustancia, cualidad, cantidad y relativos. En el artículo se presta atención a algunos aspectos del tratamiento aristotélico de la categoría de relativos y se trata de mostrar cómo hay en él elementos ya presentes en los diálogos de Platón.Aristotle’s Categories was one of the texts read and commented in Medioplatonist and Neoplatonic schools. We have no evidence that Plato developed something as elaborate as the Aristotelian categories, but the Ancients found in the dialogues an advance of them. The available texts and testimonies allowed us to sustain that Plato already made a clear distinction between some of what Aristotle called “categories”, at least substance, quality, quantity and relatives. The article pays attention to some aspects of the Aristotelian treatment of the category of relatives and tries to show that in that treatment there are different elements already present in the dialogues of Plato.Fil: Santa Cruz, Maria Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires; Argentin

Conocimiento y actitudes sobre el uso de métodos anticonceptivos en mujeres en edad fértil en un centro de salud Cutervo -2023

La investigación tuvo como objetivo determinar el nivel de conocimiento y las actitudes sobre el uso de métodos anticonceptivos en mujeres de edad fértil que asisten al centro de salud Sumidero- Cutervo, 2023. El tipo de investigación fue descriptiva, de enfoque cuantitativo y de diseño no experimental. La muestra estuvo conformada por 110 mujeres en edad fértil. La técnica empleada fue la encuesta y el instrumento fue el cuestionario. En relación a los resultados, sobre la variable conocimiento se obtuvo que las mujeres de 40 años a más tienen un nivel de conocimiento bajo; además, se determinó que las mujeres del centro de salud Sumidero muestran una actitud favorable, y la relación entre ambas variables es positiva. Se concluyó que, existe un nivel medio sobre los conocimientos y las actitudes de los métodos anticonceptivos por parte de las mujeres en edad fértil.TesisCiencias de la vida y cuidado de la salud human

Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults

Background Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. Methods We used data from 3663 population-based studies with 222 million participants that measured height and weight in representative samples of the general population. We used a Bayesian hierarchical model to estimate trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children and adolescents (age 5–19 years), from 1990 to 2022 for 200 countries and territories. For adults, we report the individual and combined prevalence of underweight (BMI <18·5 kg/m2) and obesity (BMI ≥30 kg/m2). For schoolaged children and adolescents, we report thinness (BMI <2 SD below the median of the WHO growth reference) and obesity (BMI >2 SD above the median). Findings From 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in 11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed changes were true decreases. The combined prevalence increased in 162 countries (81%) for women and 140 countries (70%) for men with a posterior probability of at least 0·80. In 2022, the combined prevalence of underweight and obesity was highest in island nations in the Caribbean and Polynesia and Micronesia, and countries in the Middle East and north Africa. Obesity prevalence was higher than underweight with posterior probability of at least 0·80 in 177 countries (89%) for women and 145 (73%) for men in 2022, whereas the converse was true in 16 countries (8%) for women, and 39 (20%) for men. From 1990 to 2022, the combined prevalence of thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%) with a posterior probability of at least 0·80. The countries with highest combined prevalence of thinness and obesity in school-aged children and adolescents in 2022 were in Polynesia and Micronesia and the Caribbean for both sexes, and Chile and Qatar for boys. Combined prevalence was also high in some countries in south Asia, such as India and Pakistan, where thinness remained prevalent despite having declined. In 2022, obesity in school-aged children and adolescents was more prevalent than thinness with a posterior probability of at least 0·80 among girls in 133 countries (67%) and boys in 125 countries (63%), whereas the converse was true in 35 countries (18%) and 42 countries (21%), respectively. In almost all countries for both adults and school-aged children and adolescents, the increases in double burden were driven by increases in obesity, and decreases in double burden by declining underweight or thinness. Interpretation The combined burden of underweight and obesity has increased in most countries, driven by an increase in obesity, while underweight and thinness remain prevalent in south Asia and parts of Africa. A healthy nutrition transition that enhances access to nutritious foods is needed to address the remaining burden of underweight while curbing and reversing the increase in obesit

EPMA-World Congress 2015: Bonn, Germany. 3-5 September 2015

Table of contents A1 Predictive and prognostic biomarker panel for targeted application of radioembolisation improving individual outcomes in hepatocellular carcinoma Jella-Andrea Abraham, Olga Golubnitschaja A2 Integrated market access approach amplifying value of “Rx-CDx” Ildar Akhmetov A3 Disaster response: an opportunity to improve global healthcare Russell J. Andrews, Leonidas Quintana A4 USA PPPM: proscriptive, profligate, profiteering medicine-good for 1 % wealthy, not for 99 % unhealthy Russell J. Andrews A5 The role of IDO in a murine model of gingivitis: predictive and therapeutic potentials Babak Baban, Jun Yao Liu, Xu Qin, Tailing Wang, Mahmood S. Mozaffari A6 Specific diets for personalised treatment of diabetes type 2 Viktoriia V. Bati, Tamara V. Meleshko, Olga B. Levchuk, Nadiya V. Boyko A7 Towards personalized physiotherapeutic approach Joanna Bauer, Ewa Boerner, Halina Podbielska A8 Cells, animal, SHIME and in silico models for detection and verification of specific biomarkers of non-communicable chronic diseases Alojz Bomba, Viktor O. Petrov, Volodymyr G. Drobnych, Rostyslav V. Bubnov, Oksana M. Bykova, Nadiya V. Boyko A9 INTERACT-chronic care model: Self-treatment by patients with decision support e-Health solution Hans-Peter Brunner-La Rocca, Lutz Fleischhacker, Olga Golubnitschaja, Frank Heemskerk, Thomas Helms, Tiny Jaarsma, Judita Kinkorova, Jan Ramaekers, Peter Ruff, Ivana Schnur, Emilio Vanoli, Jose Verdu A10 PPPM in cardiovascular medicine in 2015 Hans-Peter Brunner-La Rocca A11 Magnetic resonance imaging of nanoparticles in mice, potential for theranostic and contrast media development – pilot results Rostyslav V. Bubnov, Sergiy A. Grabovetskyi, Olena M. Mykhalchenko, Natalia O. Tymoshok, Oleksandr B. Shcherbakov, Igor P. Semeniv, Mykola Y. Spivak A12 Ultrasound diagnosis for diabetic neuropathy - comparative study Rostyslav V. Bubnov, Tetyana V. Ostapenko A13 Ultrasound for stratification patients with diabetic foot ulcers for prevention and personalized treatment - pilot results Rostyslav V. Bubnov, Nazarii M. Kobyliak, Nadiya M. Zholobak, Mykola Ya. Spivak A14 Project ImaGenX – designing and executing a questionnaire on environment and lifestyle risk of breast cancer John Paul Cauchi A15 Genomics – a new structural brand of predictive, preventive and personalized medicine or the new driver as well? Dmitrii Cherepakhin, Marina Bakay, Artem Borovikov, Sergey Suchkov A16 Survey of questionnaires for evaluation of the quality of life in various medical fields Barbara Cieślik, Agnieszka Migasiewicz, Maria-Luiza Podbielska, Markus Pelleter, Agnieszka Giemza, Halina Podbielska A17 Personalized molecular treatment for muscular dystrophies Sebahattin Cirak A18 Secondary mutations in circulating tumour DNA for acquired drug resistance in patients with advanced ALK + NSCLC Marzia Del Re, Paola Bordi, Valentina Citi, Marta Palombi, Carmine Pinto, Marcello Tiseo, Romano Danesi A19 Recombinant species-specific FcεRI alpha proteins for diagnosis of IgE-mediated allergies in dogs, cats and horses Lukas Einhorn, Judit Fazekas, Martina Muhr, Alexandra Schoos, Lucia Panakova, Ina Herrmann, Krisztina Manzano-Szalai, Kumiko Oida, Edda Fiebiger, Josef Singer, Erika Jensen-Jarolim A20 Global methodology for developmental neurotoxicity testing in humans and animals early and chronically exposed to chemical contaminants Arpiné A. Elnar, Nadia Ouamara, Nadiya Boyko, Xavier Coumoul, Jean-Philippe Antignac, Bruno Le Bizec, Gauthier Eppe, Jenny Renaut, Torsten Bonn, Cédric Guignard, Margherita Ferrante, Maria Liusa Chiusano, Salvatore Cuzzocrea, Gerard O'Keeffe, John Cryan, Michelle Bisson, Amina Barakat, Ihsane Hmamouchi, Nasser Zawia, Anumantha Kanthasamy, Glen E. Kisby, Rui Alves, Oscar Villacañas Pérez, Kim Burgard, Peter Spencer, Norbert Bomba, Martin Haranta, Nina Zaitseva, Irina May, Stéphanie Grojean, Mathilde Body-Malapel, Florencia Harari, Raul Harari, Kristina Yeghiazaryan, Olga Golubnitschaja, Vittorio Calabrese, Christophe Nemos, Rachid Soulimani A21 Mental indicators at young people with attributes hypertension and pre-hypertension Maria E. Evsevyeva, Elena A. Mishenko, Zurida V. Kumukova, Evgeniy V. Chudnovsky, Tatyana A. Smirnova A22 On the approaches to the early diagnosis of stress-induced hypertension in young employees of State law enforcement agencies Maria E. Evsevyeva, Ludmila V. Ivanova, Michail V. Eremin, Maria V. Rostovtseva A23 Сentral aortic pressure and indexes of augmentation in young persons in view of risk factors Maria E. Evsevyeva, Michail V. Eremin, Vladimir I. Koshel, Oksana V. Sergeeva, Nadesgda M. Konovalova A24 Breast cancer prediction and prevention: Are reliable biomarkers in horizon? Shantanu Girotra, Olga Golubnitschaja A25 Flammer Syndrome and potential formation of pre-metastatic niches: A multi-centred study on phenotyping, patient stratification, prediction and potential prevention of aggressive breast cancer and metastatic disease Olga Golubnitschaja, Manuel Debald, Walther Kuhn, Kristina Yeghiazaryan, Rostyslav V. Bubnov, Vadym M. Goncharenko, Ulyana Lushchyk, Godfrey Grech, Katarzyna Konieczka A26 Innovative tools for prenatal diagnostics and monitoring: improving individual pregnancy outcomes and health-economy in EU Olga Golubnitschaja, Jan Jaap Erwich, Vincenzo Costigliola, Kristina Yeghiazaryan, Ulrich Gembruch A27 Immunohistochemical assessment of APUD cells in endometriosis Vadym M. Goncharenko, Vasyl O. Beniuk, Olga V. Kalenska, Rostyslav V. Bubnov A28 Updating personalized management algorithm of endometrial hyperplasia in pre-menopause women Vadym M. Goncharenko, Vasyl O. Beniuk, Rostyslav V. Bubnov, Olga Melnychuk A29 The personified treatment approach of polimorbid patients with periodontal inflammatory diseases Irina A. Gorbacheva, Lyudmila Y. Orekhova, Vadim V. Tachalov A30 Ukrainian experience in hybrid war – the challenge to update algorithms for personalized care and early prevention of different military injuries Olena I. Grechanyk, Rizvan Ya. Abdullaiev, Rostyslav V. Bubnov A31 Tear fluid biomarkers: a comparison of tear fluid sampling and storage protocols Suzanne Hagan, Eilidh Martin, Ian Pearce, Katherine Oliver A32 The correlation of dietary habits with gingival problems during menstruation Cenk Haytac, Fariz Salimov, Servin Yoksul, Anatoly A. Kunin, Natalia S. Moiseeva A33 Genomic medicine in a contemporary Spanish population of prostate cancer: our experience Bernardo Herrera-Imbroda, Sergio del Río-González, Maria Fernanda Lara, Antonia Angulo, Francisco Javier Machuca Santa-Cruz A34 Challenges, opportunities and collaborations for personalized medicine applicability in uro-oncological disease Bernardo Herrera-Imbroda, Sergio del Río-González, Maria Fernanda Lara A35 Metabolic hallmarks of cancer as targets for a personalized therapy John Ionescu A36 Influence of genetic polymorphism as a predictor of the development of periodontal disease in patients with gastric ulcer and 12 duodenal ulcer Alfiya Z. Isamulaeva, Anatoly A. Kunin, Shamil Sh. Magomedov, Aida I. Isamulaeva A37 Challenges in diabetic macular edema Tatjana Josifova A38 Overview of the EPMA strategies in laboratory medicine relevant for PPPM Marko Kapalla, Juraj Kubáň, Olga Golubnitschaja, Vincenzo Costigliola A39 EPMA initiative for effective organization of medical travel: European concepts and criteria Vincenzo Costigliola, Marko Kapalla, Juraj Kubáň, Olga Golubnitschaja A40 Design and innovation in e-textiles: implications for PPPM Anthony Kent, Tom Fisher, Tilak Dias A41 Biobank in Pilsen as a member of national node BBMRI_CZ Judita Kinkorová, Ondřej Topolčan A42 Big data in personalized medicine: hype and hope Matthias Kohl A43 The 3P approach as the platform of the European Dentistry Department (DPPPD) Anatoly A. Kunin, Natalia S. Moiseeva A44 The endometrium cytokine patterns for predictive diagnosis of proliferation severity and cancer prevention Andrii I. Kurchenko, Vasyl A. Beniuk, Vadym M. Goncharenko, Rostyslav V. Bubnov, Nadiya V. Boyko, Andriy M. Strokan A45 A monocyte-based in-vitro system for testing individual responses to the implanted material: future for personalized implant construction Julia Kzhyshkowska, Alexandru Gudima, Ksenia S. Stankevich, Victor D. Filimonov4, Harald Klüter, Evgeniya M. Mamontova, Sergei I. Tverdokhlebov A46 Prediction and prevention of adverse health effects by meteorological factors: Biomarker patterns and creation of a device for self-monitoring and integrated care Ulyana B. Lushchyk, Viktor V. Novytskyy, Igor P. Babii, Nadiya G. Lushchyk, Lyudmyla S. Riabets, Ivanna I. Legka A47 Targeting "disease signatures" towards personalized healthcare Mira Marcus-Kalish, Alexis Mitelpunkt, Tal Galili, Neta Shachar, Yoav Benjamini A48 Influence of the skin imperfection on the personal quality of life and possible tools for objective diagnosis Agnieszka Migasiewicz, Markus Pelleter, Joanna Bauer, Ewelina Dereń, Halina Podbielska A49 The new direction in caries prevention based on the ultrastructure of dental hard tissues and filling materials Natalia S. Moiseeva, Anatoly A. Kunin, Dmitry A. Kunin A50 The use of LED radiation in prevention of dental diseases Natalia S. Moiseeva, Yury A. Ippolitov, Dmitry A. Kunin, Alexei N. Morozov, Natalia V. Chirkova, Nakhid T. Aliev A51 Status of endothelial progenitor cells in diabetic nephropathy: predictive and preventive potentials Mahmood S. Mozaffari, Jun Yao Liu, Babak Baban A52 The status of glucocorticoid-induced leucine zipper protein in salivary gland in Sjögren’s syndrome: predictive and personalized treatment potentials Mahmood S. Mozaffari, Jun Yao Liu, Rafik Abdelsayed, Xing-Ming Shi, Babak Baban A53 Maximal aerobic capacity - important quality marker of health Jaroslav Novák, Milan Štork, Václav Zeman A54 The EMPOWER project: laboratory medicine and Horizon 2020 Wytze P. Oosterhuis, Elvar Theodorsson A55 Personality profile manifestations in patient’s attitude to oral care and adherence to doctor’s prescriptions Lyudmila Y. Orekhova, Tatyana V. Kudryavtseva, Elena R. Isaeva, Vadim V. Tachalov, Ekaterina S. Loboda A56 Results of an European survey on personalized medicine addressed to directions of laboratory medicine Mario Pazzagli, Francesca Malentacchi, Irene Mancini, Ivan Brandslund, Pieter Vermeersch, Matthias Schwab, Janja Marc, Ron H.N. van Schaik, Gerard Siest, Elvar Theodorsson, Chiara Di Resta A57 MCI or early dementia predictive speech based diagnosis techniques Matus Pleva, Jozef Juhar A58 Personalized speech based mobile application for eHealth Matus Pleva, Jozef Juhar A59 Circulating tumor cell-free DNA as the biomarker in the management of cancer patients Jiří Polívka jr., Filip Janků, Martin Pešta, Jan Doležal, Milena Králíčková, Jiří Polívka A60 Complex stroke care – educational programme in Stroke Centre University Hospital Plzen Jiří Polívka, Alena Lukešová, Nina Müllerová, Petr Ševčík, Vladimír Rohan A61 Sleep apnea and sleep fragmentation contribute to brain aging Kneginja Richter, Lence Miloseva, Günter Niklewski A62 Personalised approach for sleep disturbances in shift workers Kneginja Richter, Jens Acker, Guenter Niklewski A63 Medical travel and innovative PPPM clusters: new concept of integration Olga Safonicheva, Vincenzo Costigliola A64 Medical travel and women health Olga Safonicheva A65 Continuity of generations in the training of specialists in the field of reconstructive microsurgery Maxim Sautin, Janna Sinelnikova, Sergey Suchkov A66 Telemonitoring of stroke patients – empirical evidence of individual risk management results from an observational study in Germany Songül Secer, Stephan von Bandemer A67 Women’s increasing breast cancer risk with n-6 fatty acid intake explained by estrogen-fatty acid interactive effect on DNA damage: implications for gender-specific nutrition within personalized medicine Niva Shapira A68 Cytobacterioscopy of the gingival crevicular fluid as a method for preventive diagnosis of periodontal diseases Aleksandr Shcherbakov, Anatoly A. Kunin, Natalia S. Moiseeva A69 Use of specially treated composites in dentistry to avoid violations of aesthetics Bogdan R. Shumilovich, Zhanna Lipkind, Yulia Vorobieva, Dmitry A. Kunin, Anastasiia V. Sudareva A70 National eHealth system – platform for preventive, predictive and personalized diabetes care Ivica Smokovski, Tatjana Milenkovic A72 The common energy levels of Prof. Szent-Györgyi, the intrinsic chemistry of melanin, and the muscle physiopathology. Implications in the context of Preventive, Predictive, and Personalized Medicine Arturo Solís-Herrera, María del Carmen Arias-Esparza, Sergey Suchkov A73 Plurality and individuality of hepatocellular carcinoma: PPPM perspectives Krishna Chander Sridhar, Olga Golubnitschaja A74 Strategic aspects of higher medical education reforms to secure newer educational platforms for getting biopharma professionals matures Maria Studneva, Sihong Song, James Creeden, Мark Мandrik, Sergey Suchkov A75 Overview of the strategies and activities of the European Federation of Clinical Chemistry and Laboratory Medicine, (EFLM) Elvar Theodorsson, EFLM A76 New spectroscopic techniques for point of care label free diagnostics Syed A. M. Tofail A77 Tumor markers for personalized medicine and oncology - the role of Laboratory Medicine Ondřej Topolčan, Judita Kinkorová, Ondřej Fiala, Marie Karlíková, Šárka Svobodová, Radek Kučera, Radka Fuchsová, Vladislav Třeška, Václav Šimánek, Ladislav Pecen, Jan Šoupal, Štěpán Svačina2 A78 Modern medical terminology (MMT) as a driver of the global educational reforms Evgeniya Tretyak, Maria Studneva, Sergey Suchkov A79 Juvenile hypertension; the relevance of novel predictive, preventive and personalized assessment of its determinants Francesca M. Trovato, G. Fabio Martines, Daniela Brischetto, Daniela Catalano, Giuseppe Musumeci, Guglielmo M. Trovato A80 Proteomarkers Biotech George Th. Tsangaris, Athanasios K. Anagnostopoulos A81 Proteomics and mass spectrometry based non-invasive prenatal testing of fetal health and pregnancy complications George Th. Tsangaris, Athanasios K. Anagnostopoulos A82 Integrated Ecosystem for an Integrated Care model for Heart Failure (HF) patients including related comorbidities (ZENITH) José Verdú, German Gutiérrez, Jordi Rovira, Marta Martinez, Lutz Fleischhacker, Donna Green, Arthur Garson, Elena Tamburini, Stefano Cuomo, Juan Martinez-Leon, Teresa Abrisqueta, Hans-Peter Brunner-La Rocca, Tiny Jaarsma, Teresa Arredondo, Cecilia Vera, Giuseppe Fico, Olga Golubnitschaja, Fernando Arribas, Martina Onderco, Isabel Vara, on behalf of ZENITH consortium A83 Predictive, preventive and personalized medicine in diabetes onset and complication (MOSAIC project) José Verdú, Francesco Sambo, Barbara Di Camillo, Claudio Cobelli, Andrea Facchinetti, Giuseppe Fico, Riccardo Bellazzi, Lucia Sacchi, Arianna Dagliati, Daniele Segnani, Valentina Tibollo, Manuel Ottaviano, Rafael Gabriel, Leif Groop, Jacqueline Postma, Antonio Martinez, Liisa Hakaste, Tiinamaija Tuomi, Konstantia Zarkogianni, on behalf of MOSAIC consortium A84 Possibilities for personalized therapy of diabetes using in vitro screening of insulin and oral hypoglycemic agents Igor Volchek, Nina Pototskaya, Andrey Petrov A85 The innovative technology for personalized therapy of human diseases based on in vitro drug screening Igor Volchek, Nadezhda Pototskaya, Andrey Petrov A86 Bone destruction and temporomandibular joint: predictive markers, pathogenetic aspects and quality of life Ülle Voog-Oras, Oksana Jagur, Edvitar Leibur, Priit Niibo, Triin Jagomägi, Minh Son Nguyen, Chris Pruunsild, Dagmar Piikov, Mare Saag A87 Sub-optimal health management – global vision for concepts in medical travel Wei Wang A88 Sub-optimal health management: synergic PPPM-TCAM approach Wei Wang A89 Innovative technologies for minimal invasive diagnostics Andreas Weinhäusel, Walter Pulverer, Matthias Wielscher, Manuela Hofner, Christa Noehammer, Regina Soldo, Peter Hettegger, Istvan Gyurjan, Ronald Kulovics, Silvia Schönthaler, Gabriel Beikircher, Albert Kriegner, Stephan Pabinger, Klemens Vierlinger A90 Rare disease diobanks for personalized medicine Ayşe Yüzbaşıoğlu, Meral Özgüç, Member of EuroBioBank - European Network of DNA, Cell and Tissue Banks for Rare Disease