Impact of MOF-5 on pyrrolidinium-based poly(ionic liquid)/ionic liquid membranes for biogas upgrading

PostprintBearing in mind that Metal Organic Frameworks (MOFs) have remarkable CO2 adsorption selectivity and Mixed Matrix Membranes (MMMs) have been identified as potential solution for advancing the current state of the art of membrane separation technology, this work investigates the effect of combining a MOF, with high adsorption properties towards CO2 when compared to CH4 (MOF-5), with a blend of poly(ionic liquid)/ionic liquid (PIL/IL) for biogas upgrading. The blend system consisted of a pyrrolidinium-based PIL, poly([Pyr11][Tf2N]), and a free imidazolium-based IL, [C2mim][BETI]. The MOF-5 was incorporated at different loadings (10, 20, 30 wt%), and MMMs were prepared by solvent evaporation technique and characterized by diverse techniques (FTIR, SEM, TGA, puncture tests, water contact angle and single gas transport). The results showed that the free IL is miscible with the PIL, while MOF-5 particles were uniformly dispersed into the PIL/IL matrix. The formed PIL/IL/MOF-5 membranes revealed suitable thermal stability (Tonset up to 656 K) for biogas upgrading processes, but a loss of mechanical stability was found after the incorporation of MOF-5, and thus more rigid and fragile membranes were obtained. Besides, increasing MOF-5 content in the MMMs resulted in improved CO2 permeability. At 30 wt% of MOF-5 loading the CO2 permeability increased 133% when compared to that of the pristine PIL/IL membrane, while the ideal selectivity CO2/CH4 decreases. It was possible to demonstrate the relevance of studying different components within the polymeric matrix in order to assess not only thermal, mechanical and chemical properties, but also gas transport response.This work was supported by FCT (Fundação para Ciência e a Tecnologia) through the project PTDC/CTM-POL/2676/2014 and the Associate Laboratory for Green Chemistry - LAQV (UID/QUI/50006/2019). Ana R. Nabais and Luísa A. Neves are grateful to FCT/MCTES for their PhD grant (SFRH/BD/136963/2018) and FCT Investigador Contract (IF/00505/2014), respectively. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement no. 745734

A structural equation model of self-regulation and healthy habits as an individual protective tool in the context of epidemics evidence from COVID-19

The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation.Objective: The present study aims to explore the mediation role of self-regulation on health-related behaviors adoption or maintenance, mental health, and well-being during the COVID-19 confinement in a sample of adults in Portugal. Design: One-hundred fifty individuals (118 females, 32 males; Mage = 33.57 year; SD = 12.71) filled an online survey to assess self-regulation, healthy behaviors, mental health, and well-being perception, during the early months of the pandemic (June–August, 2020). Main Outcome Measures: Self-regulation capacity, adoption or maintenance of healthy habits, mental health, including stress management, and the perception of one’s well-being were evaluated using a structural equation model (SEM). Results: Self-regulation had direct effects on healthy habits and mental health and indirect effects on well-being and mental health mediated by healthy habits. In specific, a positive direct effect on healthy habits (β = 0.497, p < 0.001) and a negative direct effect on mental health (β = −0.428, p < 0.001); and a positive indirect effect on well-being perception, mediated by healthy behaviors and mental health (β = 0.253, p = 0.003), and a negative indirect effect on mental health, mediated by healthy habits (β = −0.208, p = 0.003). Additionally, healthy habits exerted direct effects on well-being perception and mental health. A positive direct effect on well-being perception (β = 0.254, p = 0.012), and a negative direct effect on mental health (β = −0.418, p < 0.001) were further observed. No direct effect of mental health was observed in well-being perception (β = −0.199, p = 0.068). Finally, a negative correlation was observed between self-regulation and weeks of confinement (r = −0.208, p = 0.021). Conclusion: Self-regulation seems to be a good indicator of adopting a healthy lifestyle and better mental health and well-being in the context of the COVID-19 pandemic. Future preventive actions and interventions to build long-term global preparedness for future health emergencies, such as COVID-19, should explore the importance of self-regulation as an important individual and collective protective factor.This study was conducted at the Psychology Research Center (PSI/01662), School of Psychology, University of Minho, and supported by the Portuguese Foundation for Science and Technology (FCT) through the Portuguese State Budget (UIDB/PSI/01662/2020). This study was also supported by the project 2018-1-PT01-KA201-047417, funded by the ERASMUS+ Education and Training National Agency. SS was supported by the project PTDC/PSI-ESP/28228/2017, funded by the Portuguese Foundation for Science and Technology (FCT) and the European Regional Development Fund (FEDER). AS-F was supported by FCT and the Portuguese Ministry of Science, Technology and Higher Education, through the national funds, within the scope of the Transitory Disposition of the Decree No. 57/2016, 29th of August, amended by Law No. 57/2017 of 19 July. MF was supported by the UMINHO/BIM-CNCG/2021/29 Research Fellowship funded by the Portuguese Foundation for Science and Technology (FCT). SC acknowledges the Psychology for Positive Development Research Center (PSI/04375), Lusíada University of Porto, Porto, Portugal, supported by national funds through the Portuguese Foundation for Science and Technology, I.P., and the Portuguese Ministry of Science, Technology and Higher Education (UID/PSI/04375/2019)

Psycholinguistic abilities of children with Williams syndrome

The objective of this study was to investigate the psycholinguistic abilities of children with Williams syndrome (WS) and typically developing children using the Illinois Test of Psycholinguistic Abilities (ITPA). Performance on the ITPA was analysed in a group with WS (N = 20, mean age = 8.5 years, SD = 1.62) and two typically developing groups, matched in mental (MA, N = 20, mean age = 4.92 years, SD = 1.14) and chronological age (CA, N = 19, mean age = 8.35 years, SD = 3.07). Overall, within-group analyses showed that individuals with WS displayed higher scalar scores on the visual reception and visual association subtests. When groups were compared, we observed inferior performance of the WS group on all ITPA subtests when compared with typically developing groups. Moreover, an interaction between reception and group was found, only the WS group demonstrated superior performance on the visual reception subtest when compared to the auditory reception subtest. Evidence from this study offers relevant contributions to the development of educational intervention programs for children with WS.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior/CAPES (Processo: 1551/08-6) e Prope-UNESP-Santander and grant PIC/IC/83290/2007 from the Fundação para a Ciência e Tecnologia (FCT)

Interplay between the salience and the default mode network in a social-cognitive task toward a close other

Social cognition relies on two main subsystems to construct the understanding of others, which are sustained by different social brain networks. One of these social networks is the default mode network (DMN) associated with the socio-cognitive subsystem (i.e., mentalizing), and the other is the salience network (SN) associated with the socio-affective route (i.e., empathy). The DMN and the SN are well-known resting state networks that seem to constitute a baseline for the performance of social tasks. We aimed to investigate both networks' functional connectivity (FC) pattern in the transition from resting state to social task performance. A sample of 38 participants involved in a monogamous romantic relationship completed a questionnaire of dyadic empathy and underwent an fMRI protocol that included a resting state acquisition followed by a task in which subjects watched emotional videos of their romantic partner and elaborated on their partner's (Other condition) or on their own experience (Self condition). Independent component and ROI-to-ROI correlation analysis were used to assess alterations in task-independent (Rest condition) and task-dependent (Self and Other conditions) FC. We found that the spatial FC maps of the DMN and SN evidenced the traditional regions associated with these networks in the three conditions. Anterior and posterior DMN regions exhibited increased FC during the social task performance compared to resting state. The Other condition revealed a more limited SN's connectivity in comparison to the Self and Rest conditions. The results revealed an interplay between the main nodes of the DMN and the core regions of the SN, particularly evident in the Self and Other conditions.info:eu-repo/semantics/publishedVersio

Impacto psicológico da pandemia em estudantes universitários e a Linha de Apoio Psicológico SOS COVID-19 (APsi-UMinho e EPsi)

Neste capítulo apresentamos a linha de apoio psicológico SOS COVID-19, da iniciativa da APsi-UMinho, criada com o propósito de responder às necessidades da co-munidade UMinho, emergentes no contexto da pandemia COVID-19. Com efeito, a literatura empírica tem demonstrado, a propósito do impacto psicológico de epidemias passadas e da pandemia COVID-19, que a comunidade estudantil universitária repre-senta um dos grupos de risco para o desenvolvimento de perturbação psicológica que merece particular atenção. Este conhecimento justifica o planeamento e implementa-ção de ações atempadas e dirigidas para intervenções em situações de crise e para a pre-venção do agravamento de problemas emergentes, que se descrevem neste capítul

Telephone-based psychological crisis intervention: the Portuguese experience with COVID-19

Published online: 07 Jun 2020Portugal is one of the European countries that implemented early protective measures in the context of the COVID-19 pandemic. Portugal declared a state of emergency on 18 March, and a set of regional and national preventive public health measures was progressively implemented. Studies on the psychological impact of pandemics show evidence of the negative impact on mental health. Of particular concern are individuals with previous fragility (e.g. personal, family or occupational) and those undergoing life transitions. In this paper, we present a telephone-based psychological crisis intervention that was implemented to provide brief, appropriate, and timely psychological help. This intervention follows standard models of crisis intervention and is structured in five phases and five different intervention modules to take into account the impact of the pandemic on the mental health of specific risk groups. With these support services, we hope to help our community better cope with the immediate impact of the pandemic and to contribute to preventing serious mental health problems in the medium and long term.This study was partially conducted at the Psychology Research Centre (PSI/01662), University of Minho, and supported by the Portuguese Foundation for Science and Technology and the Portuguese Ministry of Science, Technology and Higher Education (UID/PSI/01662/2019), through the national funds (PIDDAC). We acknowledge Associação de Psicologia da Universidade do Minho (APsi-UMinho) and APsiUMinho collaborators for supporting the telephone-based psychological crisis intervention: Ana Daniela Silva, Ana Isabel Gonçalves, Ana Rita Pereira, Andreia Milhazes, Ângela Ferreira, Alexandra Vieira, Célia Sampaio, Carina Magalhães, Cátia Braga, Delfina Fernandes, Dulce Lopes, Dulce Pinto, Inês Castro, Inês Marques, Gabriela Santana, Joana Andrade, Joana Coutinho, Joana Guimarães, Joana Soares, Joana Teixeira, Joana Torres, João Batista, João Tiago Oliveira, Mariana Leite, Marta Sousa, Patrícia Mendes, Sara Lima, Soraia Mesquita, Teresa Castanho. We would like to thanks P5 and affiliated Psychologists: Liliana Amorim, and Inês Fernandes. We gratefully acknowledge OutSystems for the financial support through OutSystems COVID-19 Community Response Program

Major discrepancy between clinical diagnosis of death and anatomopathological findings in adolescents with chronic diseases during 18-years

Objectives: To evaluate the inconsistency between clinical diagnosis of death and autopsy findings in adolescents with chronic diseases. Methods: A cross-sectional study including a sample of adolescents’ autopsies who died in a pediatric and adolescent tertiary hospital over&nbsp;18&nbsp;consecutive years. During this period, there were n&nbsp;=&nbsp;2912 deaths, and n&nbsp;=&nbsp;581/2912(20%) occurred in adolescents. Of these, n&nbsp;=&nbsp;85/581(15%) underwent autopsies and were analyzed. Further results were divided into two groups: Goldman classes&nbsp;I&nbsp;or&nbsp;II (high disagreement between main clinical diagnosis of death and anatomopathological findings, n&nbsp;=&nbsp;26) and Goldman classes&nbsp;III, IV or&nbsp;V (low or no disagreement between these two parameters, n&nbsp;=&nbsp;59). Results: Median age at death (13.5&nbsp;[10‒19] vs. 13&nbsp;[10‒19] years, p&nbsp;=&nbsp;0.495) and disease duration (22&nbsp;[0‒164]&nbsp;vs.&nbsp;20&nbsp;[0‒200] months, p&nbsp;=&nbsp;0.931), and frequencies for males (58%&nbsp;vs.&nbsp;44%, p&nbsp;=&nbsp;0.247) were similar between class I/II&nbsp;vs.&nbsp;class&nbsp;III/IV/V. The frequency of pneumonia (73%&nbsp;vs.&nbsp;48%, p&nbsp;=&nbsp;0.029), pulmonary abscess (12%&nbsp;vs.&nbsp;0%, p&nbsp;=&nbsp;0.026), as well as isolation of yeast (27%&nbsp;vs.&nbsp;5%, p&nbsp;=&nbsp;0.008), and virus (15%&nbsp;vs.&nbsp;2%, p&nbsp;=&nbsp;0.029) identified in the autopsy, were significantly higher in adolescents with Goldman class&nbsp;I/II compared to those with Goldman class&nbsp;III/IV/V. In contrast, cerebral edema was significantly lower in adolescents of the first group (4%&nbsp;vs.&nbsp;25%, p&nbsp;=&nbsp;0.018). Conclusion: This study showed that&nbsp;30% of the adolescents with chronic diseases had major discrepancies between clinical diagnosis of death and autopsy findings. Pneumonia, pulmonary abscess, as well as isolation of yeast and virus were more frequently identified at autopsy findings in the groups with major discrepancies

Soil biochemistry and microbial activity in vineyards under conventional and organic management at Northeast Brazil.

The São Francisco Submedium Valley is located at the Brazilian semiarid region and is an important center for irrigated fruit growing. This region is responsible for 97% of the national exportation of table grapes, including seedless grapes. Based on the fact that orgThe São Francisco Submedium Valley is located at the Brazilian semiarid region and is an important center for irrigated fruit growing. This region is responsible for 97% of the national exportation of table grapes, including seedless grapes. Based on the fact that organic fertilization can improve soil quality, we compared the effects of conventional and organic soil management on microbial activity and mycorrhization of seedless grape crops. We measured glomerospores number, most probable number (MPN) of propagules, richness of arbuscular mycorrhizal fungi (AMF) species, AMF root colonization, EE-BRSP production, carbon microbial biomass (C-MB), microbial respiration, fluorescein diacetate hydrolytic activity (FDA) and metabolic coefficient (qCO2). The organic management led to an increase in all variables with the exception of EE-BRSP and qCO2. Mycorrhizal colonization increased from 4.7% in conventional crops to 15.9% in organic crops. Spore number ranged from 4.1 to 12.4 per 50 g-1 soil in both management systems. The most probable number of AMF propagules increased from 79 cm-3 soil in the conventional system to 110 cm-3 soil in the organic system. Microbial carbon, CO2 emission, and FDA activity were increased by 100 to 200% in the organic crop. Thirteen species of AMF were identified, the majority in the organic cultivation system. Acaulospora excavata, Entrophospora infrequens, Glomus sp.3 and Scutellospora sp. were found only in the organically managed crop. S. gregaria was found only in the conventional crop. Organically managed vineyards increased mycorrhization and general soil microbial activity

Hydrogen peroxide production regulates the mitochondrial function in insulin resistant muscle cells: Effect of catalase overexpression

AbstractThe mitochondrial redox state plays a central role in the link between mitochondrial overloading and insulin resistance. However, the mechanism by which the ROS induce insulin resistance in skeletal muscle cells is not completely understood. We examined the association between mitochondrial function and H2O2 production in insulin resistant cells. Our hypothesis is that the low mitochondrial oxygen consumption leads to elevated ROS production by a mechanism associated with reduced PGC1α transcription and low content of phosphorylated CREB. The cells were transfected with either the encoded sequence for catalase overexpression or the specific siRNA for catalase inhibition. After transfection, myotubes were incubated with palmitic acid (500μM) and the insulin response, as well as mitochondrial function and fatty acid metabolism, was determined. The low mitochondrial oxygen consumption led to elevated ROS production by a mechanism associated with β-oxidation of fatty acids. Rotenone was observed to reduce the ratio of ROS production. The elevated H2O2 production markedly decreased the PGC1α transcription, an effect that was accompanied by a reduced phosphorylation of Akt and CREB. The catalase transfection prevented the reduction in the phosphorylated level of Akt and upregulated the levels of phosphorylated CREB. The mitochondrial function was elevated and H2O2 production reduced, thus increasing the insulin sensitivity. The catalase overexpression improved mitochondrial respiration protecting the cells from fatty acid-induced, insulin resistance. This effect indicates that control of hydrogen peroxide production regulates the mitochondrial respiration preventing the insulin resistance in skeletal muscle cells by a mechanism associated with CREB phosphorylation and β-oxidation of fatty acids

Posterior cortical atrophy and Alzheimer’s disease : a meta-analytic review of neuropsychological and brain morphometry studies

This paper presents the first systematic review and meta-analysis of neuropsychological and brain morphometry studies comparing posterior cortical atrophy (PCA) to typical Alzheimer's disease (tAD). Literature searches were conducted for brain morphometry and neuropsychological studies including a PCA and a tAD group. Compared to healthy controls (HC), PCA patients exhibited significant decreases in temporal, occipital and parietal gray matter (GM) volumes, whereas tAD patients showed extensive left temporal atrophy. Compared to tAD patients, participants with PCA showed greater GM volume reduction in the right occipital gyrus extending to the posterior lobule. In addition, PCA patients showed less GM volume loss in the left parahippocampal gyrus and left hippocampus than tAD patients. PCA patients exhibit significantly greater impairment in Immediate Visuospatial Memory as well as Visuoperceptual and Visuospatial Abilities than patients with tAD. However, tAD patients showed greater impairment in Delayed Auditory/Verbal Memory than patients with PCA. PCA is characterized by significant atrophy of the occipital and parietal regions and severe impairments in visuospatial functioning.JA is funded by a doctoral grant from the Foundation for Science and Technology, FCT (SFRH/BD/64457/2009, co-funded by FSE/POPH). JA and AS are funded by project PIC/IC/83290/2007, which is supported by FEDER (POFC-COMPETE) and FCT. JMS is supported by a fellowship of the project SwitchBox-FP7-HEALTH-2010-grant 259772-2. These organizations had no role in the study design, data collection, analysis, interpretation, or in the decision to submit the paper for publication