30 research outputs found
The trend in the development of a system that combines the placement and use of tangible assets such as warehouses, terminals, and storage facilities of enterprises
The article discusses the idea of creating an Internet resource in order to combine the needs and offers of services for storage, transportation, rental of warehouses, premises, open storage areas, etc. in the Tomsk region
The dynamics of near-surface prismatic loops in lead
The paper proposes the study of the dynamics of near-surface dislocation loops in lead. It has been shown that the activation of a prismatic near-surface dislocation loop and its motion inward the crystal practically throughout the entire path occurs at a high velocity close to the speed of sound in metal. The kinetic energy per unit length of the dislocation loop during its motion decreases linearly and weakly depends on the density of dislocations in metal. Moreover, a weak dependence of the path length and the path time of a prismatic loop on the dislocation density in lead is observed
ΠΠΎΡΠ»ΡΠ΄ΠΆΠ΅Π½Π½Ρ ΠΌΠΎΡΡΠΎΡΡΠ½ΠΊΡΡΠΎΠ½Π°Π»ΡΠ½ΠΈΡ ΠΎΡΠΎΠ±Π»ΠΈΠ²ΠΎΡΡΠ΅ΠΉ ΡΠΎΠ·Π²ΠΈΡΠΊΡ Π΅ΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΠΈΡ ΠΌΠ΅ΡΠ°Π»ΠΎΠ½Π΅ΡΡΠΎΠΏΠ°ΡΡΠΉ = The study of morphofunctional features of the development of experimental metallonephropathy
Gozhenko A. I., Lugovskoy S. P., Samokhina N. A. ΠΠΎΡΠ»ΡΠ΄ΠΆΠ΅Π½Π½Ρ ΠΌΠΎΡΡΠΎΡΡΠ½ΠΊΡΡΠΎΠ½Π°Π»ΡΠ½ΠΈΡ
ΠΎΡΠΎΠ±Π»ΠΈΠ²ΠΎΡΡΠ΅ΠΉ ΡΠΎΠ·Π²ΠΈΡΠΊΡ Π΅ΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΠΈΡ
ΠΌΠ΅ΡΠ°Π»ΠΎΠ½Π΅ΡΡΠΎΠΏΠ°ΡΡΠΉ = The study of morphofunctional features of the development of experimental metallonephropathy. Journal of Education, Health and Sport. 2016;6(4):287-296. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.50201http://ojs.ukw.edu.pl/index.php/johs/article/view/3473Β The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2015).755 Journal of Education, Health and Sport eISSN 2391-8306 7Β© The Author (s) 2016;This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, PolandOpen Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercialuse, distribution and reproduction in any medium, provided the work is properly cited.The authors declare that there is no conflict of interests regarding the publication of this paper.Received: 20.03.2016. Revised 17.04.2016. Accepted: 17.04.2016.Β ΠΠΠ‘ΠΠΠΠΠΠΠΠ― ΠΠΠ Π€ΠΠ€Π£ΠΠΠ¦ΠΠΠΠΠΠ¬ΠΠΠ₯ ΠΠ‘ΠΠΠΠΠΠΠ‘Π’ΠΠ Π ΠΠΠΠΠ’ΠΠ£ ΠΠΠ‘ΠΠΠ ΠΠΠΠΠ’ΠΠΠ¬ΠΠΠ₯ ΠΠΠ’ΠΠΠΠΠΠ€Π ΠΠΠΠ’ΠΠ Β Π. Π. ΠΠΎΠΆΠ΅Π½ΠΊΠΎ, Π‘. Π. ΠΡΠ³ΠΎΠ²ΡΡΠΊΠΈΠΉ, Π. Π. Π‘Π°ΠΌΠΎΡ
ΡΠ½Π° Β ΠΠ΅ΡΠΆΠ°Π²Π½Π΅ ΠΏΡΠ΄ΠΏΡΠΈΡΠΌΡΡΠ²ΠΎ Β«Π£ΠΊΡΠ°ΡΠ½ΡΡΠΊΠΈΠΉ Π½Π°ΡΠΊΠΎΠ²ΠΎ-Π΄ΠΎΡΠ»ΡΠ΄Π½ΠΈΠΉ ΡΠ½ΡΡΠΈΡΡΡΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΠΈ ΡΡΠ°Π½ΡΠΏΠΎΡΡΡ ΠΠΠ Π£ΠΊΡΠ°ΡΠ½ΠΈΒ», ΠΌ. ΠΠ΄Π΅ΡΠ°, Π£ΠΊΡΠ°ΠΈΠ½Π°Β Π Π΅Π·ΡΠΌΠ΅ΠΡΠΎΠ²Π΅Π΄Π΅Π½Ρ Π΅ΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½Ρ Π΄ΠΎΡΠ»ΡΠ΄ΠΆΠ΅Π½Π½Ρ ΡΠΎΠ΄ΠΎ ΡΡΠΈΠ²Π°Π»ΠΎΠ³ΠΎ Π²ΠΏΠ»ΠΈΠ²Ρ ΡΠΎΠ»Π΅ΠΉ ΠΊΠ°Π΄ΠΌΡΡ, ΡΡΡΡΡ, ΡΠ²ΠΈΠ½ΡΡ Π² Π΄ΠΎΠ·Ρ 1/50 Π²ΡΠ΄ DL50 Π½Π° Π½ΠΈΡΠΊΠΈ ΠΏΠΎΠΊΠ°Π·Π°Π»ΠΈ, ΡΠΎ Π²Π°ΠΆΠ»ΠΈΠ²ΠΈΠΌ Π°ΡΠΏΠ΅ΠΊΡΠΎΠΌ ΡΡ
Π΄ΡΡ Ρ Π·ΠΌΡΠ½Π° ΠΏΠΎΠΊΠ°Π·Π½ΠΈΠΊΡΠ² Π°Π·ΠΎΡΠΈΡΡΠΎΠ³ΠΎ ΠΎΠ±ΠΌΡΠ½Ρ, ΡΠΊΠ° ΠΏΡΠΎΡΠ²Π»ΡΠ»Π°ΡΡ ΠΏΡΠ΄Π²ΠΈΡΠ΅Π½ΠΈΠΌ Π²ΠΌΡΡΡΠΎΠΌ ΠΊΡΠ΅Π°ΡΠΈΠ½ΡΠ½Ρ, ΡΠ΅ΡΠΎΠ²ΠΈΠ½ΠΈ ΡΠ° ΡΠ΅ΡΠΎΠ²ΠΎΡ ΠΊΠΈΡΠ»ΠΎΡΠΈ Π² ΡΠΈΡΠΎΠ²Π°ΡΡΡ ΠΊΡΠΎΠ²Ρ, Π° ΡΠ°ΠΊΠΎΠΆ Π²ΠΈΡΠΎΠΊΠΈΠΌ Π²ΠΌΡΡΡΠΎΠΌ Π±ΡΠ»ΠΊΡ Π² ΡΠ΅ΡΡ. Π₯Π°ΡΠ°ΠΊΡΠ΅ΡΠ½ΠΎΡ ΠΎΠ·Π½Π°ΠΊΠΎΡ ΡΡΠ°ΠΆΠ΅Π½Π½Ρ Π½ΠΈΡΠΎΠΊ Ρ Π·Π½ΠΈΠΆΠ΅Π½Π½Ρ ΡΠ²ΠΈΠ΄ΠΊΠΎΡΡΡ ΠΊΠ»ΡΠ±ΠΎΡΠΊΠΎΠ²ΠΎΡ ΡΡΠ»ΡΡΡΠ°ΡΡΡ, ΡΠΊΠ° Π²ΠΈΠ·Π½Π°ΡΠ°Π»Π°ΡΡ ΠΏΡΠΈ Π΄ΡΡ Π²ΡΡΡ
ΡΡΡΠΎΡ
Π΄ΠΎΡΠ»ΡΠ΄ΠΆΡΠ²Π°Π½ΠΈΡ
Π½Π΅ΡΡΠΎΡΠΎΠΊΡΠΈΠΊΠ°Π½ΡΡΠ²: ΠΏΡΠΈ Π΄ΡΡ Cd β Π·Π½ΠΈΠΆΠ΅Π½Π½Ρ Π½Π° 23,6 %, ΠΏΡΠΈ Π΄ΡΡ Pb β Π½Π° 22,1 %, ΠΏΡΠΈ Π΄ΡΡ Hg β 28,9 %. ΠΠΎΡΡΠΎΠ»ΠΎΠ³ΡΡΠ½Ρ Π΄ΠΎΡΠ»ΡΠ΄ΠΆΠ΅Π½Π½Ρ Π΄ΠΎΠ·Π²ΠΎΠ»ΠΈΠ»ΠΈ Π²ΡΡΠ°Π½ΠΎΠ²ΠΈΡΠΈ Π½ΠΎΠ²Ρ ΡΠ°ΠΊΡΠΈ, ΡΠΎΠ΄ΠΎ ΠΌΠΎΡΡΠΎΠ»ΠΎΠ³ΡΡΠ½ΠΎΡ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊΠΈ ΡΠΎΠΊΡΠΈΡΠ½ΠΎΡ Π΄ΡΡ Π½Π΅ΠΎΡΠ³Π°Π½ΡΡΠ½ΠΈΡ
ΡΠΏΠΎΠ»ΡΠΊ Cd, Hg, Pb, ΡΠΊΡ ΠΏΠΎΠ»ΡΠ³Π°ΡΡΡ Ρ Π·Π΄Π°ΡΠ½ΠΎΡΡΡ ΠΌΠ΅ΡΠ°Π»ΡΠ² Π²ΠΈΠΊΠ»ΠΈΠΊΠ°ΡΠΈ ΡΠΈΡΠΎΠΏΠ°ΡΠΈΡΠ½Ρ Π΄ΡΡ Π½Π° ΠΎΠΊΡΠ΅ΠΌΡ ΠΊΠ»ΡΡΠΈΠ½ΠΈ ΡΡΡΡΠΊΡΡΡΠ½ΠΈΡ
Π΅Π»Π΅ΠΌΠ΅Π½ΡΡΠ² Π½Π΅ΡΡΠΎΠ½Ρ. ΠΡΠΎΠ²ΡΠ΄Π½ΠΈΠΌ ΠΌΠ΅Ρ
Π°Π½ΡΠ·ΠΌΠΎΠΌ ΡΠΎΠ·Π²ΠΈΡΠΊΡ Π΅ΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΠΈΡ
ΠΌΠ΅ΡΠ°Π»ΠΎΠ½Π΅ΡΡΠΎΠΏΠ°ΡΡΠΉ Ρ ΡΡΠ°ΠΆΠ΅Π½Π½Ρ Π΅ΠΏΡΡΠ΅Π»ΡΡ ΠΏΡΠΎΠΊΡΠΈΠΌΠ°Π»ΡΠ½ΠΈΡ
ΠΊΠ°Π½Π°Π»ΡΡΡΠ² Π½ΠΈΡΠΎΠΊ, ΡΠΊΠ΅ Π·ΡΠΌΠΎΠ²Π»Π΅Π½ΠΎ Π²ΠΈΠ±ΡΡΠΊΠΎΠ²ΠΈΠΌ ΠΏΠΎΡΡΡΠ΅Π½Π½ΡΠΌ ΠΊΠ»ΡΡΠΈΠ½Π½ΠΈΡ
ΠΌΠ΅ΠΌΠ±ΡΠ°Π½, ΠΌΡΡΠΎΡ
ΠΎΠ½Π΄ΡΡΠΉ Ρ Π»ΡΠ·ΠΎΡΠΎΠΌ Π΅ΠΏΡΡΠ΅Π»ΡΡ ΠΏΡΠΎΠΊΡΠΈΠΌΠ°Π»ΡΠ½ΠΈΡ
ΠΊΠ°Π½Π°Π»ΡΡΡΠ² Π½Π΅ΡΡΠΎΠ½Ρ.ΠΠ»ΡΡΠΎΠ²Ρ ΡΠ»ΠΎΠ²Π°: Π²Π°ΠΆΠΊΡ ΠΌΠ΅ΡΠ°Π»ΠΈ, Π½ΠΈΡΠΊΠΈ, ΠΌΠ΅ΡΠ°Π»ΠΎΠ½Π΅ΡΡΠΎΠΏΠ°ΡΡΡ, ΠΊΡΠ΅Π°ΡΠΈΠ½ΡΠ½, ΡΠ΅ΡΠΎΠ²ΠΈΠ½Π°, Π±ΡΠ»ΠΎΠΊ, ΡΠ²ΠΈΠ΄ΠΊΡΡΡΡ ΠΊΠ»ΡΠ±ΠΎΡΠΊΠΎΠ²ΠΎΡ ΡΡΠ»ΡΡΡΠ°ΡΡΡ, Π³ΡΡΡΠΎΠ»ΠΎΠ³ΡΡΠ½Π΅ Π΄ΠΎΡΠ»ΡΠ΄ΠΆΠ΅Π½Π½Ρ Π½ΠΈΡΠΎΠΊ, ΠΊΠ°Π½Π°Π»ΡΡΠ΅Π²ΠΈΠΉ Π°ΠΏΠ°ΡΠ°Ρ, Π΅ΠΏΡΡΠ΅Π»ΡΠΎΡΠΈΡΠΈ.Β THE STUDY OF MORPHOFUNCTIONAL FEATURES OF THE DEVELOPMENT OF EXPERIMENTAL METALLONEPHROPATHYΒ A. I. Gozhenko, S. P. Lugovskoy, N. A. Samokhina Β Ukrainian Scientific and Research Institute of Transport Medicine, OdessaΒ SummaryEexperimental studies of prolonged exposure of cadmium salts, mercury, lead in the dose of from 1/50 DL50 on the kidney have shown that an important aspect of their actions is the change of indicators of nitrogen metabolism, which was manifested by increased creatinine, urea and uric acid in serum and high urine protein excretion. A characteristic feature of renal disease is the decline in glomerular filtration rate, which was defined when all three of the studied nephrotoxicants: under the Cd decrease by 23,6 %, under the action of Pb - 22,1 %, under the action of Hg β 28,9 %. Morphological studies revealed new facts concerning the morphological characteristics of toxic action of inorganic compounds of Cd, Hg, Pb, which lies in the ability of metals to cause cytopathic effect on individual cells of the structural elements of the nephron. The main mechanism for the development of experimental metallonephropathy is the damage to the epithelium of the proximal tubules of the kidneys, due to a selective disturbance of cellular membranes, mitochondria and lysosomes in the epithelium of the proximal tubules of the nephron.Key words: heavy metals, kidneys, metallonephropathy, creatinine, urea, protein, glomerular filtration rate, and histological examination of the kidneys, tubular apparatus, the epithelial cells.Β ΠΠ‘Π‘ΠΠΠΠΠΠΠΠΠ ΠΠΠ Π€ΠΠ€Π£ΠΠΠ¦ΠΠΠΠΠΠ¬ΠΠ«Π₯ ΠΠ‘ΠΠΠΠΠΠΠ‘Π’ΠΠ Π ΠΠΠΠΠ’ΠΠ― ΠΠΠ‘ΠΠΠ ΠΠΠΠΠ’ΠΠΠ¬ΠΠ«Π₯ ΠΠΠ’ΠΠΠΠΠΠΠ€Π ΠΠΠΠ’ΠΠ Β Π. Π. ΠΠΎΠΆΠ΅Π½ΠΊΠΎ, Π‘. Π. ΠΡΠ³ΠΎΠ²ΡΠΊΠΎΠΉ, Π. Π. Π‘Π°ΠΌΠΎΡ
ΠΈΠ½Π°Β Π£ΠΊΡΠ°ΠΈΠ½ΡΠΊΠΈΠΉ ΠΠΠ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½Ρ ΡΡΠ°Π½ΡΠΏΠΎΡΡΠ°, Π³.ΠΠ΄Π΅ΡΡΠ°Β Π Π΅Π·ΡΠΌΠ΅ΠΡΠΎΠ²Π΅Π΄Π΅Π½Π½ΡΠ΅ ΡΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΡΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π΄Π»ΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ Π²ΠΎΠ·Π΄Π΅ΠΉΡΡΠ²ΠΈΡ ΡΠΎΠ»Π΅ΠΉ ΠΊΠ°Π΄ΠΌΠΈΡ, ΡΡΡΡΠΈ, ΡΠ²ΠΈΠ½ΡΠ° Π² Π΄ΠΎΠ·Π΅ 1/50 DL50 Π½Π° ΠΏΠΎΡΠΊΠΈ ΠΏΠΎΠΊΠ°Π·Π°Π»ΠΈ, ΡΡΠΎ Π²Π°ΠΆΠ½ΡΠΌ Π°ΡΠΏΠ΅ΠΊΡΠΎΠΌ ΠΈΡ
Π΄Π΅ΠΉΡΡΠ²ΠΈΡ ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ Π°Π·ΠΎΡΠΈΡΡΠΎΠ³ΠΎ ΠΎΠ±ΠΌΠ΅Π½Π°, ΠΊΠΎΡΠΎΡΠΎΠ΅ ΠΏΡΠΎΡΠ²Π»ΡΠ»ΠΎΡΡ ΠΏΠΎΠ²ΡΡΠ΅Π½Π½ΡΠΌ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅ΠΌ ΠΊΡΠ΅Π°ΡΠΈΠ½ΠΈΠ½Π°, ΠΌΠΎΡΠ΅Π²ΠΈΠ½Ρ ΠΈ ΠΌΠΎΡΠ΅Π²ΠΎΠΉ ΠΊΠΈΡΠ»ΠΎΡΡ Π² ΡΡΠ²ΠΎΡΠΎΡΠΊΠ΅ ΠΊΡΠΎΠ²ΠΈ, Π° ΡΠ°ΠΊΠΆΠ΅ Π²ΡΡΠΎΠΊΠΈΠΌ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅ΠΌ Π±Π΅Π»ΠΊΠ° Π² ΠΌΠΎΡΠ΅. Π₯Π°ΡΠ°ΠΊΡΠ΅ΡΠ½ΡΠΌ ΠΏΡΠΈΠ·Π½Π°ΠΊΠΎΠΌ ΠΏΠΎΡΠ°ΠΆΠ΅Π½ΠΈΡ ΠΏΠΎΡΠ΅ΠΊ ΡΠ²Π»ΡΠ΅ΡΡΡ ΡΠ½ΠΈΠΆΠ΅Π½ΠΈΠ΅ ΡΠΊΠΎΡΠΎΡΡΠΈ ΠΊΠ»ΡΠ±ΠΎΡΠΊΠΎΠ²ΠΎΠΉ ΡΠΈΠ»ΡΡΡΠ°ΡΠΈΠΈ, ΠΊΠΎΡΠΎΡΠ°Ρ ΠΎΠΏΡΠ΅Π΄Π΅Π»ΡΠ»Π°ΡΡ ΠΏΡΠΈ Π΄Π΅ΠΉΡΡΠ²ΠΈΠΈ Π²ΡΠ΅Ρ
ΡΡΠ΅Ρ
ΠΈΡΡΠ»Π΅Π΄ΡΠ΅ΠΌΡΡ
Π½Π΅ΡΡΠΎΡΠΎΠΊΡΠΈΠΊΠ°Π½ΡΠΎΠ²: ΠΏΡΠΈ Π΄Π΅ΠΉΡΡΠ²ΠΈΠΈ Cd β ΡΠ½ΠΈΠΆΠ΅Π½ΠΈΠ΅ Π½Π° 23,6 %, ΠΏΡΠΈ Π΄Π΅ΠΉΡΡΠ²ΠΈΠΈ Pb β Π½Π° 22,1 %, ΠΏΡΠΈ Π΄Π΅ΠΉΡΡΠ²ΠΈΠΈ Hg β 28,9 %. ΠΠΎΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΠΏΠΎΠ·Π²ΠΎΠ»ΠΈΠ»ΠΈ ΡΡΡΠ°Π½ΠΎΠ²ΠΈΡΡ Π½ΠΎΠ²ΡΠ΅ ΡΠ°ΠΊΡΡ, ΠΎΡΠ½ΠΎΡΠΈΡΠ΅Π»ΡΠ½ΠΎ ΠΌΠΎΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΉ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊΠΈ ΡΠΎΠΊΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π΄Π΅ΠΉΡΡΠ²ΠΈΡ Π½Π΅ΠΎΡΠ³Π°Π½ΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠΎΠ΅Π΄ΠΈΠ½Π΅Π½ΠΈΠΉ Cd, Hg, Pb, ΠΊΠΎΡΠΎΡΡΠ΅ Π·Π°ΠΊΠ»ΡΡΠ°ΡΡΡΡ Π² ΡΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡΠΈ ΠΌΠ΅ΡΠ°Π»Π»ΠΎΠ² Π²ΡΠ·ΡΠ²Π°ΡΡ ΡΠΈΡΠΎΠΏΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠ΅ Π΄Π΅ΠΉΡΡΠ²ΠΈΠ΅ Π½Π° ΠΎΡΠ΄Π΅Π»ΡΠ½ΡΠ΅ ΠΊΠ»Π΅ΡΠΊΠΈ ΡΡΡΡΠΊΡΡΡΠ½ΡΡ
ΡΠ»Π΅ΠΌΠ΅Π½ΡΠΎΠ² Π½Π΅ΡΡΠΎΠ½Π°. ΠΠ΅Π΄ΡΡΠΈΠΌ ΠΌΠ΅Ρ
Π°Π½ΠΈΠ·ΠΌΠΎΠΌ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΡΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΡΡ
ΠΌΠ΅ΡΠ°Π»ΠΎΠ½Π΅ΡΡΠΎΠΏΠ°ΡΠΈΠΉ ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΏΠΎΡΠ°ΠΆΠ΅Π½ΠΈΠ΅ ΡΠΏΠΈΡΠ΅Π»ΠΈΡ ΠΏΡΠΎΠΊΡΠΈΠΌΠ°Π»ΡΠ½ΡΡ
ΠΊΠ°Π½Π°Π»ΡΡΠ΅Π² ΠΏΠΎΡΠ΅ΠΊ, ΠΊΠΎΡΠΎΡΠΎΠ΅ ΠΎΠ±ΡΡΠ»ΠΎΠ²Π»Π΅Π½ΠΎ Π²ΡΠ±ΠΎΡΠΎΡΠ½ΡΠΌ Π½Π°ΡΡΡΠ΅Π½ΠΈΠ΅ΠΌ ΠΊΠ»Π΅ΡΠΎΡΠ½ΡΡ
ΠΌΠ΅ΠΌΠ±ΡΠ°Π½, ΠΌΠΈΡΠΎΡ
ΠΎΠ½Π΄ΡΠΈΠΉ ΠΈ Π»ΠΈΠ·ΠΎΡΠΎΠΌ ΡΠΏΠΈΡΠ΅Π»ΠΈΡ ΠΏΡΠΎΠΊΡΠΈΠΌΠ°Π»ΡΠ½ΡΡ
ΠΊΠ°Π½Π°Π»ΡΡΠ΅Π² Π½Π΅ΡΡΠΎΠ½Π°.ΠΠ»ΡΡΠ΅Π²ΡΠ΅ ΡΠ»ΠΎΠ²Π°: ΡΡΠΆΠ΅Π»ΡΠ΅ ΠΌΠ΅ΡΠ°Π»Π»Ρ, ΠΏΠΎΡΠΊΠΈ, ΠΌΠ΅ΡΠ°Π»Π»ΠΎΠ½Π΅ΡΡΠΎΠΏΠ°ΡΠΈΠΈ, ΠΊΡΠ΅Π°ΡΠΈΠ½ΠΈΠ½, ΠΌΠΎΡΠ΅Π²ΠΈΠ½Π°, Π±Π΅Π»ΠΎΠΊ, ΡΠΊΠΎΡΠΎΡΡΡ ΠΊΠ»ΡΠ±ΠΎΡΠΊΠΎΠ²ΠΎΠΉ ΡΠΈΠ»ΡΡΡΠ°ΡΠΈΠΈ, Π³ΠΈΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ ΠΏΠΎΡΠ΅ΠΊ, ΠΊΠ°Π½Π°Π»ΡΡΠ΅Π²ΡΠΉ Π°ΠΏΠΏΠ°ΡΠ°Ρ, ΡΠΏΠΈΡΠ΅Π»ΠΈΠΎΡΠΈΡΡ
Fluorine concentration in snow cover within the impact area of aluminium production plant (Krasnoyarsk city) and coal and gas-fired power plant (Tomsk city)
The fluorine contents in snow melt water find in the impact areas of aluminum production plant and coal and gas-fired power plant are compared. In melt water, soluble fluoride is found in the form of fluoride ion, the content of which was determined by the potentiometric method using ion-selective electrode. According to the measurements of 2013-2014, fluoride content in melt water ranges 10.6-15.4 mg/dm{3} at the distance 1-3 km from the borders of Krasnoyarsk aluminum plant with the mean value 13.1 mg/dm{3}. Four-year monitoring from 2012 to 2015 in the impact area of Tomsk coal and gas-fired power plant showed that fluoride content in melt water in vicinity of the thermal power plant is significantly lower than in the samples from the impact area of the aluminum plant. But higher content of fluoride ion (0.2-0.3 mg/dm{3}) in snow samples in vicinity of coal and gas-fired power plant was revealed in winter of 2015. Intake of soluble fluoride is mostly explained by dust-aerosol emissions of study plants and deposition of fluorine compounds from air
Analysis of Microcrafters in Materials Specimens after Long-Term Exposure on ISS Surface
The "Komplast" experiment has been carried out on the ISS by the Khrunichev Space Center jointly with other Russian scientific centers since 1998. The experiment incorporates the "Komplast" cartridges on the FGB exterior, which are fitted with materials specimens and sensors. The cartridges were sent into orbit together with FGB on 20 November 1998. In March 2011, two of the cartridges were taken back from the ISS by the "Discovery" American space shuttle after being exposed in the open space for 12 years. In the framework of this experiment the subject of analysis is the effect of the space environment on the exposed specimens of various materials. This report covers the analysis results of the surface morphology of various materials taken from the "Komplast" cartridges exposed to hits of micrometeors and micronic particles of space debris. Analysis is made of microcraters of 5 to 250 mcm in specimens of polished metals and silicone comprised in the sensor for micrometeoric particles. The report represents optic and scanning electron microscope images of craters formed in the specimens by high-velocity and low-velocity particles impacting the surface. By virtue of the electronic microscope, data on composition of the substance in the craters and of the substance of the low-velocity particles are obtained. The data make it possible to differentiate the particles as the natural-origin particles or anthropogenic-origin space debris particles. Distribution of craters and low-velocity particles in the size range of 5 to 50 mcm is obtained. The data are compared with the existing models of fluxes of natural-origin and artificial-origin microparticles on the ISS orbit. Inhomogeneous particles of complicated configuration are discovered on the surface of the analyzed specimens, whose origin are not uniquely determined and are to be the subject of further study
A Study of Micro Craters in Material Samples after Long Duration Exposure on ISS Komplast Panels
The Komplast materials experiment was designed by the Khrunichev State Research and Production Space Center, together with other Russian scientific institutes, and has been carried out by Mission Control Moscow since 1998. Komplast panels fitted with material samples and sensors were located on the International Space Station (ISS) Functional Cargo Block (FGB) module exterior surface. Within the framework of this experiment, the purpose was to study the effect of the low earth orbit (LEO) environment on exposed samples of various materials. The panels were sent into orbit with the FGB when it launched on November 20, 1998.
ΠΠΎΡΠ»ΡΠ΄ΠΆΠ΅Π½Π½Ρ Π½Π΅ΡΡΠΎΠΏΡΠΎΡΠ΅ΠΊΡΠΎΡΠ½ΠΎΡ Π΄ΡΡ ΡΠΎΡΠ½ΠΈΡΡ ΠΏΡΠΈ Π΅ΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΠΈΡ ΠΌΠ΅ΡΠ°Π»ΠΎΠ½Π΅ΡΡΠΎΠΏΠ°ΡΡΡΡ
Experimental studies of the effect of heavy metals, in particular, the salts of cadmium and lead, on the activity of the antioxidant system of the kidneys have been carried out and also the nephroprotective properties of the polyphenol complex of blueberries has been investigated. A positive effect of the drug in question characterized by a stimulation of the antioxidant defense system, an activation of the enzymes of the glutathione antioxidant system (GAOS) as well as increased levels of the elimination of heavy metals from the body.ΠΡΠΎΠ²Π΅Π΄Π΅Π½Ρ ΡΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΡΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π²Π»ΠΈΡΠ½ΠΈΡ ΡΡΠΆΠ΅Π»ΡΡ
ΠΌΠ΅ΡΠ°Π»Π»ΠΎΠ², Π² ΡΠ°ΡΡΠ½ΠΎΡΡΠΈ, ΡΠΎΠ»Π΅ΠΉ ΠΊΠ°Π΄ΠΌΠΈΡ ΠΈ ΡΠ²ΠΈΠ½ΡΠ°, Π½Π° Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ Π°Π½ΡΠΈΠΎΠΊΡΠΈΠ΄Π°Π½ΡΠ½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ ΠΏΠΎΡΠ΅ΠΊ, Π° ΡΠ°ΠΊΠΆΠ΅ ΠΈΠ·ΡΡΠ΅Π½Ρ Π½Π΅ΡΡΠΎΠΏΡΠΎΡΠ΅ΠΊΡΠΎΡΠ½ΡΠ΅ ΡΠ²ΠΎΠΉΡΡΠ²Π° ΠΏΠΎΠ»ΠΈΡΠ΅Π½ΠΎΠ»ΡΠ½ΠΎΠ³ΠΎ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ° ΡΠ΅ΡΠ½ΠΈΠΊΠΈ. ΠΡΡΠ²Π»Π΅Π½ ΠΏΠΎΠ·ΠΈΡΠΈΠ²Π½ΡΠΉ ΡΡΡΠ΅ΠΊΡ ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΠ°, ΠΊΠΎΡΠΎΡΡΠΉ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΠ·ΡΠ΅ΡΡΡ ΡΡΠΈΠΌΡΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ΠΌΒ ΡΠΈΡΡΠ΅ΠΌΡ Π°Π½ΡΠΈΠΎΠΊΡΠΈΠ΄Π°Π½ΡΠ½ΠΎΠΉ Π·Π°ΡΠΈΡΡ, Π°ΠΊΡΠΈΠ²Π°ΡΠΈΠ΅ΠΉ ΡΠ΅ΡΠΌΠ΅Π½ΡΠΎΠ² ΠΠΠΠ‘, Π° ΡΠ°ΠΊΠΆΠ΅ ΡΠΎΡΡΠΎΠΌ ΡΡΠΎΠ²Π½Π΅ΠΉ ΡΠ»ΠΈΠΌΠΈΠ½Π°ΡΠΈΠΈ ΡΡΠΆΠ΅Π»ΡΡ
ΠΌΠ΅ΡΠ°Π»Π»ΠΎΠ² ΠΈΠ· ΠΎΡΠ³Π°Π½ΠΈΠ·ΠΌΠ°.ΠΡΠΎΠ²Π΅Π΄Π΅Π½Ρ Π΅ΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½Ρ Π΄ΠΎΡΠ»ΡΠ΄ΠΆΠ΅Π½Π½Ρ ΡΠΎΠ΄ΠΎ Π²ΠΏΠ»ΠΈΠ²Ρ Π²Π°ΠΆΠΊΠΈΡ
ΠΌΠ΅ΡΠ°Π»ΡΠ², Π·ΠΎΠΊΡΠ΅ΠΌΠ° ΡΠΎΠ»Π΅ΠΉ ΡΠ²ΠΈΠ½ΡΡ ΡΠ° ΠΊΠ°Π΄ΠΌΡΡ, Π½Π° Π°ΠΊΡΠΈΠ²Π½ΡΡΡΡ Π°Π½ΡΠΈΠΎΠΊΡΠΈΠ΄Π°Π½ΡΠ½ΠΎΡ ΡΠΈΡΡΠ΅ΠΌΠΈ Π½ΠΈΡΠΎΠΊ, Π° ΡΠ°ΠΊΠΎΠΆ Π΄ΠΎΡΠ»ΡΠ΄ΠΆΠ΅Π½ΠΎ Π½Π΅ΡΡΠΎΠΏΡΠΎΡΠ΅ΠΊΡΠΎΡΠ½Ρ Π²Π»Π°ΡΡΠΈΠ²ΠΎΡΡΡ ΠΏΠΎΠ»ΡΡΠ΅Π½ΠΎΠ»ΡΠ½ΠΎΠ³ΠΎ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΡ ΡΠΎΡΠ½ΠΈΡΡ. ΠΠΈΡΠ²Π»Π΅Π½ΠΎ ΠΏΠΎΠ·ΠΈΡΠΈΠ²Π½ΠΈΠΉ Π΅ΡΠ΅ΠΊΡ Π΄Π°Π½ΠΎΠ³ΠΎ ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΡ, ΡΠΊΠΈΠΉ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΠ·ΡΡΡΡΡΡ ΡΡΠΈΠΌΡΠ»ΡΠ²Π°Π½Π½ΡΠΌ ΡΠΈΡΡΠ΅ΠΌΠΈ Π°Π½ΡΠΈΠΎΠΊΡΠΈΠ΄Π°Π½ΡΠ½ΠΎΠ³ΠΎ Π·Π°Ρ
ΠΈΡΡΡ, Π°ΠΊΡΠΈΠ²Π°ΡΡΡΡ ΡΠ΅ΡΠΌΠ΅Π½ΡΡΠ² Π³Π»ΡΡΠ°ΡΡΠΎΠ½Π°Π½ΡΠΈΠΎΠΊΡΠΈΠ΄Π°Π½ΡΠ½ΠΎΡ ΡΠΈΡΡΠ΅ΠΌΠΈ (ΠΠΠΠ‘), Π° ΡΠ°ΠΊΠΎΠΆ ΠΏΡΠ΄Π²ΠΈΡΠ΅Π½Π½ΡΠΌ ΡΡΠ²Π½ΡΠ² Π΅Π»ΡΠΌΡΠ½Π°ΡΡΡ Π²Π°ΠΆΠΊΠΈΡ
ΠΌΠ΅ΡΠ°Π»ΡΠ² Π· ΠΎΡΠ³Π°Π½ΡΠ·ΠΌΡ
Myofascial pain syndrome: risk factors, diagnosis and local therapy
One of the main reasons for seeking medical help is myofascial syndrome (MFS), which is manifested by local inflammation with elements of degenerative changes in the affected tissue, pain and muscle spasm due to dysfunctional disorders in the nociceptive system and a decrease in the quality of life. This review discusses etiopathogenesis in detail, taking into account the factors predisposing to the development of MFS, which are divided into anatomical, ergonomic, medical and psychosocial, and also provides diagnostic criteria for pain MFS, including 5 large and 3 small criteria necessary for diagnosis. The second part of the review examines the indications, efficacy, safety, and benefits of topical forms of nonsteroidal anti-inflammatory drugs (NSAIDs), which have a moderate effect on pain, but have a much better safety profile due to reduced systemic absorption. The use of topical drugs allows you to create an effective concentration of the drug directly in the lesion and avoid undesirable systemic effects. Experts strongly recommend prescribing primarily topical, rather than oral, NSAIDs to patients aged 65 years and older who have concomitant cardiovascular and renal pathology, as well as diseases of the gastrointestinal tract. In more detail, the review examines topical forms of diclofenac, which differ in the maximum degree of transdermal penetration compared to other NSAIDs and the effect of slow release of the active substance into the surrounding tissues