8 research outputs found

    Bone as a Possible Target of Chemical Toxicity of Natural Uranium in Drinking Water

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    Uranium accumulates in bone, affects bone metabolism in laboratory animals, and when ingested in drinking water increases urinary excretion of calcium and phosphate, important components in the bone structure. However, little is known about bone effects of ingested natural uranium in humans. We studied 146 men and 142 women 26–83 years of age who for an average of 13 years had used drinking water originating from wells drilled in bedrock, in areas with naturally high uranium content. Biochemical indicators of bone formation were serum osteocalcin and amino-terminal propeptide of type I procollagen, and a marker for bone resorption was serum type I collagen carboxy-terminal telopeptide (CTx). The primary measure of uranium exposure was uranium concentration in drinking water, with additional information on uranium intake and uranium concentration in urine. The data were analyzed separately for men and women with robust regression (which suppresses contributions of potential influential observations) models with adjustment for age, smoking, and estrogen use. The median uranium concentration in drinking water was 27 ÎŒg/L (interquartile range, 6–116 ÎŒg/L). The median of daily uranium intake was 36 ÎŒg (7–207 ÎŒg) and of cumulative intake 0.12 g (0.02–0.66 g). There was some suggestion that elevation of CTx (p = 0.05) as well as osteocalcin (p = 0.19) could be associated with increased uranium exposure (uranium in water and intakes) in men, but no similar relationship was found in women. Accordingly, bone may be a target of chemical toxicity of uranium in humans, and more detailed evaluation of bone effects of natural uranium is warranted

    Kaivo-opas

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    Kaivo-opas on laadittu erityisesti uuden kaivon rakentamista tai vanhan kunnostamista suunnitteleville. Oppaaseen on koottu tiivistettyÀ tietoa pohjaveden esiintymisestÀ maa- ja kallioperÀssÀ, pohjaveden laadusta ja sitÀ heikentÀvistÀ tekijöistÀ sekÀ kaivon paikan valinnasta. Tavallisen rengaskaivon rakentaminen on kuvattu yksityiskohtaisesti piirroksilla havainnollistettuna. Piirroksia on myös porakaivosta ja erÀistÀ muista kaivotyypeistÀ. Oppaassa selostetaan lisÀksi vanhan kaivon kunnostus- ja huoltotoimenpiteet. LiitteissÀ on esitetty yksityisten kaivojen talousveden laatuvaatimukset ja -suositukset, yleisimmÀt veden laatuhaitat ja niiden poistamismahdollisuudet

    Brunnsguide

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    Brunnsguiden har gjorts sÀrskilt med tanke pÄ dem som planerar att bygga en ny brunn eller restaurera en gammal. I guiden har man samlat information om grundvattenförekomst i mark och i berggrund, grundvattnets kvalitet och faktorer som försÀmrar kvaliteten samt valet av brunnsplatsens geografiska lÀge. Byggande av vanliga brunnar med cementringar finns detaljerat beskrivet och detta har illustrerats med bilder. Det finns ocksÄ bilder av borrbrunnar och nÄgra övriga brunnstyper. I guiden finns dessutom beskrivet restaurerings- och underhÄllsÄtgerder för gamla brunnar. I bilagorna finns förevisat kvalitetskrav och rekommedationer för hushÄllsvatten frÄn privata brunnar, de vanligaste kvalitativa bristerna i vattnet samt Ätgerder för att avhjÀlpa dem
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