A method to assess the economic impacts of forest biomass use on ecosystem services in a National Park

The aim of the paper is to develop a method to assess the effect of forest biomass use for energy on ecosystem services (ES). Such method has been in the GRASS GIS environment, by creating an Decision Support System (DSS) called r.green.biomassfor. The method has been tested in the Triglav National Park in Slovenia. The potential forest biomass was estimated with r.green.biomassfor DSS taking into account the effects of forest biomass harvesting on ES in terms of economic value. The economic value of each ecosystem service to society has been estimated using different economic evaluation methods and were spatially located with a Geographical Information System (GIS) application. Then, a semi-structured questionnaire was administered face-to-face to the experts in order to understand the effects of forest biomass harvesting on the ES at local level. Finally, the results of the questionnaire survey were elaborated to obtain indicators useful to assess the economic gain or loss on the benefits provided by ES based on the results of r.green.biomassfor DSS. © 2017 Elsevier Ltd. All rights reserve

Neoplastic Leg Ulcers

Skin biopsy is an important procedure for a correct diagnosis of varying skin conditions, from inflammatory to neoplastic diseases. Nevertheless, some authors still consider this procedure a high risk in patients affected by leg ulcers (LUs) and prefer reserving it for selected cases

Prospettive e potenzialità della digitalizzazione del settore forestale in Italia

Information and Communication Technologies (ICT) play a key role for improving the implementation of sustainable forest management at local, regional, and global level. The ICT potential to easily exploit a wider and more up-to-date set of information on the economic, environmental, and so- cial value of forests is of relevant help for the daily work of technicians, land owners, and companies in boosting the efficiency and effectiveness of forest management. The concept of “Precision Forestry” (PF) was developed from the early 2000s, as a branch of precision farming or precision agriculture. PF includes the use of ICT, remote and proximal sensing technologies, and other devices to coordinate and control several processes on a spatial scale (“Precision”) for monitoring, planning, and managing forest resources (“Forestry”). The aim of this monography is to collect and describe some of the most important PF experiences applied or potential- ly useful for the Italian forestry sector. It may represent a reference guide for the stakeholders, such as forest owners, professional technicians, public administrators, and policy makers. The book includes eleven chapters reviewing the main tech- nological tools available in the Italian context and the most recent advances of ICT in forestry, also focusing on the strengths and weaknesses of their practical implementation. The opportunities and challenges of implementing PF meth- ods, practices and technologies are also discussed. In the first two chapters the precision forestry concept and its historical development are introduced. In the third chap- ter some basic elements of ICT, GIS, Global Navigation Satellite Systems (GNSS), remote/proximal sensing, and related technologies which are essential for a better compre- hension of PF applications are recalled. In chapter 4 recent advances in large scale forest inventories with a focus on mapping and on the spatial estimation of forest variables integrating field surveys and multisource re- motely sensed data are described. Current advancements in the acquisition of field information including Terrestrial La- ser Scanning (TLS), new digital dendrometers, tree-talkers, terrestrial cameras, and APP for portable devices such as smartphones or tablets for dendrometric tree measures and new citizen science applications to support quantitative and qualitative spatial estimation of forest variables over large areas (i.e., forest health, fuel types) are also presented. The chapter ends up with the description of some experiences in the implementation of Forest Information Systems in Italy to provide a simple open-access to such new generation of spatial forest information. In chapter 5 PF tools, instruments, and technologies to sup- port sustainable forest management are illustrated. APPs developed to acquire field plots data to simulate manage- ment operations, the application of photogrammetric tech- nologies from Unmanned Aerial Vehicles and TLS data for monitoring with high-spatial scale forest monitoring and for acquiring indicators at single tree level are presented. A de- tailed description of new user-friendly tools for forest roadplanning, design and construction, as well as forest opera- tion planning is also included. Precision forest tree farming (with particular reference to poplar cultivation), useful to promote and increase the prof- itability and sustainability of forest plantations within the Italian context is described in chapter 6. The innovation and enhancement within the supply chain of wood plantations (from planting to harvesting, including monitoring and identification of stress) by soil proximal sensing techniques, Early Warning Systems, and specific software are highlight- ed. Considering the even higher market demands, promoted by the large-scale planting programs for climate changes mit- igation and the demands for propagation material for en- vironmental recovery, innovative techniques and methods supported by ICT in the forest nursery sector are described in chapter 7. In chapter 8 available technologies related to precision har- vesting are analyzed and described taking into consideration the wood chain efficiency, by means of improved commu- nications between the owner/buyer and operators as well as among machineries used in forest operations, health and safety of forest operators, environmental impacts mitigation and recovery, and operators training. Advanced communi- cation systems and sensors for the exchange of data and information between machines, machine-equipments and/or machine-operators, teleoperations and automation are also described. Chapters 9 and 10 are related to wood products traceabil- ity, timber quality assessment as well as the technologies for the optimization of wood transformation processes. The concepts of wood product traceability and tracing, togeth- er with latest digital technologies for the identification and tracking of the logs (i.e., fingerprinting and RFID), are de- tailly reported. Chapter 11 is finally dedicated to the relationship between the EU policy framework and the digitalization process in both agricultural and forestry sectors. The book summarizes, under a proactive and homogeneous framework, PF methods, tools and technologies in relation with the digital transition of the Italian forestry sectors. The authors hope this book will be useful for improving the implementation of sustainable forest management practic- es at all levels in Italy, providing a comprehensive review useful for policy makers, technicians, forestry owners and students

Can a single drug administration elicit two different immunological pathways at the same time? A case report of Fixed Drug Eruption after anaphylaxis

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Use of Participatory Processes in Wood Residue Management from a Circular Bioeconomy Perspective: An Approach Adopted in Italy

The circular bioeconomy is aimed at achieving sustainable development through high efficiency utilization and resource recycling, and through combining environmental, economic and social objectives. Although the implementation of circular bioeconomy principles is based on a bottom-up approach, the participatory process has often been neglected. To overcome this problem, the present study investigated a case-study with a three-step participatory process. The process aimed to evaluate a forest-wood supply chain with consideration of the circular bioeconomy principles. A set of indicators was identified and assessed by a pool of experts. Then the members of a forest-wood supply chain were consulted to implement the identified actions. Finally, a focus group was organized with key stakeholders to discuss critical issues and strategies for enhancing the forest-wood supply chain locally. The results show that the proposed set of indicators is a useful tool to evaluate the performance of the forest-wood supply chain considering the circular bioeconomy principles. The results of the participatory process and related indicators’ assessment identified the main weaknesses of the forest-wood supply chain. The main strategies to develop the local forest-wood supply chain toward the circular bioeconomy principles were also defined with a participatory approach

Dysfunction and functional restoration of HCV-specific CD8 responses in chronic hepatitis C virus infection

The functional impairment of HCV-specific T cell responses is believed to be an important determinant of HCV persistence, but the functional T cell defects of patients with chronic hepatitis C (CH-C) are only partially defined. CD8 responses to HLA-A2-restricted epitopes of HCV and other unrelated viruses were studied in 23 HLA-A2-positive patients both ex vivo and after in vitro culture. Degranulation capacity, intracellular perforin, and granzyme-A content and cytokine production (IFN-γ, TNF-α) by HCV- and non-HCV-specific CD8 cells were tested both ex vivo and in vitro, whereas cytolytic activity was studied after 10 days' expansion in vitro. Memory maturation and role of exhaustion were assessed ex vivo by HCV-specific CD8 staining for CD 127 and PD-1, and in vitro after peripheral blood mononuclear cells (PBMC) culture in the presence of anti-PD-L1 monoclonal antibodies. IFN-γ production and cytolytic activity were expressed less efficiently by HCV-specific than by non-HCV specific CD8 cells derived from the same CH-C patients. The amount of stored granzyme-A within single cells was always lower in HCV-specific CD8 cells, which were less efficient also in the release of lytic granules and in the production of TNF-α. The CD8 dysfunction was associated with high PD-1 expression by most HCV-specific CD8 cells, and PD-1/PD-L1 blockade by anti-PD-L1 antibodies in vitro was able to improve the HCV-specific CD8 function. Conclusion: Our study characterizes CD8 defects that may be important in maintaining HCV persistence; identification of strategies to correct these defects may help to define novel approaches to treat HCV infection. Copyright © 2007 by the American Association for the Study of Liver Diseases

A comprehensive process of forest residues energy planning through public participation and DSS use in a real case in Piedmont

The work describes the application to the real case of Parco Naturale delle Alpi Marittime (Piedmont, Italy) of r.green, a DSS that is able to estimate the energy potential of renewable energies. The Open source DSS is based on GRASS GIS and was developed by EURAC, UNITN and CREA in the frame of the European project “Alpine Space recharge.green”. It contains the submodule r.green.biomassfor that was applied to calculate the forest biomass energy potential in Gesso and Vermenagna Valleys. The model was applied in a participative planning process that involved different local stakeholders like the Natural Park, forest enterprises, environmental agencies. They were asked to give their opinion regarding the possible use of forest biomass to produce energy. The results were the base to carry out further meetings in which the parameters of possible forest bioenergy development scenarios were defined. The model allowed to evaluate the maximum energetic potential on the base of mean annual increment and total prescribed yield and to calculate how much can be really extracted depending on terrain morphology and mechanization level. Through an analysis of the extraction and transportation costs and of the prices of wood and of energy, an evaluation of costs gain was carried out and only the areas were the extraction of forest biomass for energy was economically feasible were considered. The model run using the parameters suggested by stakeholders creating plausible scenarios (like the use of different extraction techniques) and incorporating the observation expressed in the different public meetings (like the number and positioning of possible power plants). The percentage of consumption that can be covered with woodchips renewable energy in different scenarios was calculated through an estimate of local consumption for residential heating. Finally, the different scenarios and the results were presented and discussed in a final public meeting with stakeholders, citizens and all interested subjects. The model was evaluated in a very positive way by the stakeholders and was the fulcrum of the participative planning process since it generated discussion and inspired alternatives, and at the same time the model was the collector of the options that were processed, summarized and displayed in the final results