Phytochemistry, traditional uses and pharmacological properties of the genus opopanax W.D.J. Koch: A Mini-Review

The genus Opopanax W.D.J. Koch is a member of the Apiaceae family, distributed throughout the Mediterranean region and comprises only three recognized and well-defined species, O. chironium (L.) W.D.J. Koch, O. hispidus (Friv.) Griseb. and O. persicus Boiss. The species of this genus with yellow flowers are well-known in traditional medicine and consumed as food. This review critically appraises published literature on the phytochemistry, traditional usages, and pharmacological activities of the genus Opopanax. In addition, it provides evidence to suggest that the plants from this genus have potential phytotherapeutic applications. Previous phytochemical and bioactivity studies revealed that the genus Opopanax predominantly produces coumarins, diterpenes, phenolics, and phthalides, and possesses various biological and pharmacological properties, including anticancer, antioxidant and antimicrobial activities. The phytochemical profile and pharmacological activities of the genus Opopanax could be useful for further study and might find additional medicinal applications in evidence-based phytotherapy

Stress analysis of ceramic insulation coating on Cu/MgB2 wires for W&R MgB2 coils

Saçlı, Ömer Asım (Arel Author)Ceramic insulation coatings were produced on Cu/MgB2 wires, which were fabricated by Hyper Tech Research Inc., using Continuous Tube Forming and Filling (CTFF) process, from the solution of Zr, and Y based organometalic compounds, solvent and chelating agent using reel-to-reel sol–gel technique for MgB2 coils. Y2O3–ZrO2/Cu/MgB2 wires were annealed at 700 ?C for 30 min with 5.8 ?C/min heating rate under 4% H2–Ar gas flow. Residual stresses were examined for Cu/MgB2 wire and YSZ coatings with varying thicknesses. It was observed that displacement values are independent from YSZ thicknesses and the maximum effective stress value is in the Cu region. The surface morphologies and microstructure of samples were characterized using SEM. SEM micrographs of the insulation coatings revealed cracks, pinholes and mosaic structure

Pregnancy associated plasma protein-A evaluation of a new biomarker in hypothyroidsm

European Congress of Clinical Biochemistry and Laboratory Medicine (EUROMEDLAB 2005) -- MAY 08-12, 2005 -- Glasgow, SCOTLANDWOS: 000229250401365…IFCC, FESC

Pregnancy associated plasma protein-A evaluation of a new biomarker in hypothyroidsm

European Congress of Clinical Biochemistry and Laboratory Medicine (EUROMEDLAB 2005) -- MAY 08-12, 2005 -- Glasgow, SCOTLANDWOS: 000229250401365…IFCC, FESC

JAK2

WOS: 000305797100012PubMed ID: 22203033The Janus kinase 2(V617F) (JAK2(V617F)) mutation is an acquired genetic defect that is considered to enhance thrombosis in Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs). Thrombosis is also a well-defined component of Behcet syndrome (BS). The aim of this study was to determine the frequency of JAK2(V617F) mutation in BS-associated thrombosis. A total of 152 patients with BS (62 with thrombosis and 90 without thrombosis) were enrolled. An additional 186 patients with MPNs and 107 healthy blood donors were included to serve as diseased and healthy controls, respectively. None of the patients with BS and healthy controls carried the JAK2(V617F) mutation, whereas 67% of patients with MPNs were positive for JAK2(V617F). The frequency of thrombosis in patients with MPNs was not statistically different between carriers and non-carriers of JAK2(V617F) mutation. Our data suggest that JAK2(V617F) is not directly related to thrombosis in MPNs and in other thrombotic entities, such as BS.Eczacibasi-Baxter Hospital Supply Inc.; Berk Ilac A.S.The author(s) disclosed receipt of the following financial support for the research, authorship and/or publication of this article: This study was partially funded by the unrestricted grants of Eczacibasi-Baxter Hospital Supply Inc. and Berk Ilac A.S