Full Bayesian analysis for a class of jump-diffusion models

A new Bayesian significance test is adjusted for jump detection in a diffusion process. This is an advantageous procedure for temporal data having extreme valued outliers, like financial data, pluvial or tectonic forces records and others.Comment: 15 pages, 7 figures; real data analysis adde

Conservation of catchments: some theoretical considerations and case histories from Rio de Janeiro

Conservation has developed along two lines: protection of species and communities, and preservation of natural resources. Catchments provide the natural unit for conservation since they are the fundamental unit of terrestrial ecosystems and account for most of the flow of materials. Urban streams of the city of Rio de Janeiro are generally well protected in their headwaters by the large urban parks in steep terrain. However, the lower reaches are often very heavily impacted by sewage, channelling, etc. Fauna that require estuarine habitats for part of their life history are excluded from such streams. Ecosystem functioning in urban streams is probably changed through the loss of strongly-interacting shrimp. Leaf decomposition was found to be reduced in urban streams compared to pristine streams in one study. Conservation entities in the state of Rio de Janeiro tend to protect the mountainous areas; piedmont and coastal plain habitats are generally impacted by agriculture and habitation. Many attempts are being made to conserve catchments in the state of Rio de Janeiro; we discuss 4 case histories, which have different constraints and employ different strategies for management and conservation. Key words: connectivity, catadromous shrimp, conservation planning and management.Conservation has developed along two lines: protection of species and communities, and preservation of natural resources. Catchments provide the natural unit for conservation since they are the fundamental unit of terrestrial ecosystems and account for most of the flow of materials. Urban streams of the city of Rio de Janeiro are generally well protected in their headwaters by the large urban parks in steep terrain. However, the lower reaches are often very heavily impacted by sewage, channelling, etc. Fauna that require estuarine habitats for part of their life history are excluded from such streams. Ecosystem functioning in urban streams is probably changed through the loss of strongly-interacting shrimp. Leaf decomposition was found to be reduced in urban streams compared to pristine streams in one study. Conservation entities in the state of Rio de Janeiro tend to protect the mountainous areas; piedmont and coastal plain habitats are generally impacted by agriculture and habitation. Many attempts are being made to conserve catchments in the state of Rio de Janeiro; we discuss 4 case histories, which have different constraints and employ different strategies for management and conservation. Key words: connectivity, catadromous shrimp, conservation planning and management

Prostaglandin E2-EP1 and EP2 receptor signaling promotes apical junctional complex disassembly of Caco-2 human colorectal cancer cells

<p>Abstract</p> <p>Background</p> <p>The apical junctional complex (AJC) is a dynamic structure responsible to maintain epithelial cell-cell adhesions and it plays important functions such as, polarity, mechanical integrity, and cell signaling. Alteration of this complex during pathological events leads to an impaired epithelial barrier by perturbation of the cell-cell adhesion system. Although clinical and experimental data indicate that prostaglandin E₂(PGE₂) plays a critical function in promoting cell motility and cancer progression, little is known concerning its role in AJC disassembly, an event that takes place at the beginning of colorectal tumorigenesis. Using Caco-2 cells, a cell line derived from human colorectal cancer, we investigated the effects of prostaglandin E₂(PGE₂) treatment on AJC assembly and function.</p> <p>Results</p> <p>Exposition of Caco-2 cells to PGE₂promoted differential alteration of AJC protein distribution, as evidenced by immunofluorescence and immunoblotting analysis and impairs the barrier function, as seen by a decrease in the transepithelial electric resistance and an increase in the permeability to ruthenium red marker. We demonstrated the involvement of EP1 and EP2 prostaglandin E₂receptor subtypes in the modulation of the AJC disassembly caused by prostanoid. Furthermore, pharmacological inhibition of protein kinase-C, but not PKA and p38MAPK significantly prevented the PGE₂effects on the AJC disassembly.</p> <p>Conclusion</p> <p>Our findings strongly suggest a central role of Prostaglandin E2-EP1 and EP2 receptor signaling to mediate AJC disassembly through a mechanism that involves PKC and claudin-1 as important target for the TJ-related effects in human colorectal cancer cells (Caco-2).</p

Conservation of catchments: some theoretical considerations and case histories from Rio de Janeiro

Conservation has developed along two lines: protection of species and communities, and preservation of natural resources. Catchments provide the natural unit for conservation since they are the fundamental unit of terrestrial ecosystems and account for most of the flow of materials. Urban streams of the city of Rio de Janeiro are generally well protected in their headwaters by the large urban parks in steep terrain. However, the lower reaches are often very heavily impacted by sewage, channelling, etc. Fauna that require estuarine habitats for part of their life history are excluded from such streams. Ecosystem functioning in urban streams is probably changed through the loss of strongly-interacting shrimp. Leaf decomposition was found to be reduced in urban streams compared to pristine streams in one study. Conservation entities in the state of Rio de Janeiro tend to protect the mountainous areas; piedmont and coastal plain habitats are generally impacted by agriculture and habitation. Many attempts are being made to conserve catchments in the state of Rio de Janeiro; we discuss 4 case histories, which have different constraints and employ different strategies for management and conservation. Key words: connectivity, catadromous shrimp, conservation planning and management.Conservation has developed along two lines: protection of species and communities, and preservation of natural resources. Catchments provide the natural unit for conservation since they are the fundamental unit of terrestrial ecosystems and account for most of the flow of materials. Urban streams of the city of Rio de Janeiro are generally well protected in their headwaters by the large urban parks in steep terrain. However, the lower reaches are often very heavily impacted by sewage, channelling, etc. Fauna that require estuarine habitats for part of their life history are excluded from such streams. Ecosystem functioning in urban streams is probably changed through the loss of strongly-interacting shrimp. Leaf decomposition was found to be reduced in urban streams compared to pristine streams in one study. Conservation entities in the state of Rio de Janeiro tend to protect the mountainous areas; piedmont and coastal plain habitats are generally impacted by agriculture and habitation. Many attempts are being made to conserve catchments in the state of Rio de Janeiro; we discuss 4 case histories, which have different constraints and employ different strategies for management and conservation. Key words: connectivity, catadromous shrimp, conservation planning and management

Borderline personality disorder and bias in the recognition of facial expressions of emotion: a pathway to understand the psychopathology

Background The identification of facial emotions is a key skill as it promotes rapid and accurate recognition of emotions and enables better communication and greater social adaptation. More recent studies have suggested that impaired social interactions may be related to deficits in social cognition and therefore in the recognition of facial expressions, contributing to social disturbance among individuals with borderline personality disorder (BPD). Objective To present the results of an empirical study assessing the recognition of facial emotion expressions in women with BPD, having as reference a group of healthy women from the general population. Methods The subjects (40 female with BPD and 40 controls) were assessed with a dynamic task on a computer screen for recognition of facial expressions of emotion. Results The BPD group had a lower accuracy in perceiving emotions of fear and surprise and slowness in recognising happiness. Logistic regression analyses also identified an association between BPD and higher sensitivity in the recognition of anger. Discussion Women with BPD made more mistakes in the recognition of negative emotions, which can bias the behaviour and regulation of affective states, favouring in turn the emergence of some typical symptoms associated with BPD

Bulbos úmidos a partir da irrigação por gotejamento subsuperficial com água de abastecimento e efluente de esgoto tratado

The use of treated sewage effluent (TSE) combined with the subsurface drip irrigation (SDI) method in agriculture can decrease the costs of agricultural production, in attempts to fertigate crops more efficiently. In this study it was compared the dimensions of the wet bulb formed by the application of TSE and municipal water supply (MWS) in an Oxisoil. We have evaluated the effect of water quality and discharge between drippers used in sugarcane crop. Three trenches were opened and 21 three-rod TDR probes were setup in a mesh and a dripper was buried at 0.30 m, for each constant discharge of 1.0 L h-1and 1.6 L h-1. Comparing results from different wetted soil profiles it was observed that the vertical and horizontal dimensions of the wet bulb are similar for both MWS and TSE, being peculiars according to the discharges used and volume applied. Regardless the water quality, an increase of 60% in discharge decreased the deepest infiltration.352242253O uso de efluente de esgoto tratado (EET), combinado com o método de irrigação por gotejamento subsuperfical (IGS) na agricultura, pode reduzir os custos de produção agrícola, fertirrigando de maneira eficiente as culturas. Neste artigo, compararam-se as dimensões do bulbo úmido formado pela aplicação de EET e água de abastecimento municipal (AAM), em um Latossolo Vermelho distroférrico. Avaliou-se o efeito da qualidade da água e da vazão entre gotejadores utilizados na cultura da cana-de-açúcar. Três trincheiras foram abertas e 21 sondas de TDR com três hastes foram instaladas em malha, e um gotejador foi enterrado a 0,30 m, para cada vazão constante de 1,0 Lh-1 e 1,6 Lh-1. Comparando os resultados de diferentes perfis de umidade do solo, sugere-se que as dimensões vertical e horizontal do bulbo úmido sejam similares para a AAM e para o EET, sendo peculiares de acordo com as vazões utilizadas e o volume aplicado. Independentemente da qualidade da água, o aumento de 60% na vazão reduziu a infiltração em profundidade

Use of manganese oxides recovered from spent batteries in electrocatalysis of oxygen reduction reaction in alkaline medium

The oxygen reduction reaction was studied in alkaline media using manganese oxides obtained from spent batteries as electrocatalysts. Three processes were used to recover manganese oxides from spent batteries. The particles obtained were in the range from 8 to 11 nm. The electrochemical experiments indicated a good electrocatalytic activity toward oxygen reduction using the different samples and showing approximately a direct transference of 4 electrons during the process. Even though all the processes were efficient, the best result was observed for the prepared sample using reactants of low cost.FAPESPCNPqCoordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)UFAB