8 research outputs found
Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility
- Author
- Abreu M.T.
- Ahmad T.
- Allez M.
- Ananthakrishnan A.N.
- Anderson C.A.
- Atzmon G.
- Avila B.
- Baras A.
- Barrett J.C.
- Barzilai N.
- Beaugerie L.
- Beecham A.
- Belgium IBD Consortium
- Bernstein C.N.
- Bitton A.
- Bokemeyer B.
- Brant S.R.
- Cedars-Sinai IBD
- Chan A.
- Cho J.
- Chung D.
- Cleynen I.
- Cosnes J.
- Cutler D.J.
- Daly A.
- Daly M.J.
- Damas O.M.
- Datta L.W.
- Dawany N.
- Devoto M.
- Dodge S.
- Duerr R.H.
- Ellinghaus E.
- Fachal L.
- Farkkila M.
- Faubion W.
- Ferreira M.
- Franchimont D.
- Franke A.
- Gabriel S.B.
- Ge T.
- Georges M.
- Gettler K.
- Giri M.
- Glaser B.
- Goerg S.
- Goyette P.
- Graham D.
- Hamalainen E.
- Haritunians T.
- Heap G.A.
- Hiltunen M.
- Hoeppner M.
- Horowitz J.E.
- Huang H.L.
- Int IBD Genetics Consortium
- Irving P.
- Iyer V.
- Jalas C.
- Kelsen J.
- Khalili H.
- Kirschner B.S.
- Kontula K.
- Koskela J.T.
- Kugathasan S.
- Kupcinskas J.
- Lamb C.A.
- Laudes M.
- Levesque C.
- Levine A.P.
- Lewis J.D.
- Liefferinckx C.
- Loescher B.S.
- Louis E.
- Mansfield J.
- May S.
- McCauley J.L.
- McGovern D.P.B.
- Mengesha E.
- Meulen A.E. van der
- Mni M.
- Moayyedi P.
- Moran C.J.
- Newberry R.D.
- NIDDK IBD Genetics Consortium
- NIHR IBD BioResource
- O'Charoen S.
- Okou D.T.
- Oldenburg B.
- Ostrer H.
- Palotie A.
- Paquette J.
- Parkes M.
- Pekow J.
- Peter I.
- Pierik M.J.
- Ponsioen C.Y.
- Pontikos N.
- Prescott N.
- Pulver A.E.
- Rahmouni S.
- Regeneron Genetics Ctr
- Rice D.L.
- Rioux J.D.
- Rivas M.A.
- Saavalainen P.
- Sands B.
- Sartor R.B.
- Sazonovs A.
- Schiff E.R.
- Schreiber S.
- Schumm L.P.
- Segal A.W.
- Seksik P.
- SHARE Consortium
- Shawky R.
- Sheikh S.Z.
- Silverberg M.S.
- Simmons A.
- Skeiceviciene J.
- Sokol H.
- Solomonson M.
- Somineni H.
- SPARC IBD Network
- Stevens C.R.
- Sun D.
- Targan S.
- Turner D.
- Uhlig H.H.
- UK IBD Genetics Consortium
- Venkataraman G.R.
- Vermeire S.
- Verstockt S.
- Voskuil M.D.
- Weersma R.K.
- Winter H.S.
- Xavier R.J.
- Young J.
- Yuan K.
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 29/08/2022
- Field of study
Genome-wide association studies (GWASs) have identified hundreds of loci associated with Crohn's disease (CD). However, as with all complex diseases, robust identification of the genes dysregulated by noncoding variants typically driving GWAS discoveries has been challenging. Here, to complement GWASs and better define actionable biological targets, we analyzed sequence data from more than 30,000 patients with CD and 80,000 population controls. We directly implicate ten genes in general onset CD for the first time to our knowledge via association to coding variation, four of which lie within established CD GWAS loci. In nine instances, a single coding variant is significantly associated, and in the tenth, ATG4C, we see additionally a significantly increased burden of very rare coding variants in CD cases. In addition to reiterating the central role of innate and adaptive immune cells as well as autophagy in CD pathogenesis, these newly associated genes highlight the emerging role of mesenchymal cells in the development and maintenance of intestinal inflammation.Large-scale sequence-based analyses identify novel risk variants and susceptibility genes for Crohn's disease, and implicate mesenchymal cell-mediated intestinal homeostasis in disease etiology.Cellular mechanisms in basic and clinical gastroenterology and hepatolog
Review of Water Distribution Systems Modelling and Performance Analysis Softwares
- Author
- Publication venue
- 'IOP Publishing'
- Publication date
- Field of study
Brown coal conversion under the action of supercritical water
- Author
- A. A. Vostrikov
- A. Marzec
- A. Wilhelm
- A.A. Aleksandrov
- A.A. Vostrikov
- A.A. Vostrikov
- A.A. Vostrikov
- C. Dariva
- C. Higman
- C. Tsonopoulos
- D. Yu. Dubov
- D.W. Krevelen Van
- E.S. Vayisolu
- G. Deak
- G. Deshpande
- I.B. Rao
- J. Hollender
- J. Wang
- L. Li
- M. Stolarski
- M. Stolarski
- M. Ya. Sokol
- N. Bhajendra
- O. N. Fedyaeva
- O.M. Ogunsola
- Q. Yuan
- R. Garcia
- S. A. Psarov
- S. Sangon
- S.S. Kutateladze
- T. Adschiri
- T. Wang
- T.M. Aida
- Yu.F. Patrakov
- Publication venue
- 'Allerton Press'
- Publication date
- Field of study
Morfologia oral interna de larvas dos gêneros Eupemphix, Physalaemus e Leptodactylus (Amphibia: Anura)
- Author
- Adelina Ferreira
- ALCADE L.
- BILATE M.
- BOKERMANN W.C.A.
- CARAMASCHI U.
- CEI J.M.
- D'Heursel A.
- D'Heursel A.
- de Sá R.O.
- De SÁ R.O.
- ETEROVICK P.C.
- FROST D.R.
- FROST D.R.
- GOSNER K.L.
- GRANT T.
- HAAS A.
- HEYER W.R.
- HEYER W.R.
- HEYER W.R.
- HEYER W.R.
- KEHR A. I.
- LYNCH J.D.
- NASCIMENTO L.B.
- NASCIMENTO L.B.
- NOMURA F.
- Núbia Esther de Oliveira Miranda
- PEROTTI M.G.
- PEROTTI M.G.
- PRADO C.P.A.
- PUGENER L.A.
- ROSSA-FERES D.C.
- ROSSA-FERES D.C.
- SANDOVAL M.T.
- SANDOVAL M.T.
- SANDOVAL M.T.
- SOKOL O.M.
- WASSERSUG R.J.
- WASSERSUG R.J.
- WASSERSUG R.J.
- WEBER L.N.
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Morphological characterization and taxonomic key of tadpoles (Amphibia: Anura) from the northern region of the Atlantic Forest
- Author
- ABRAVAYA J.P.
- ABREU R.O.
- ABREU R.O.
- ABREU R.O.
- Adrian Antonio Garda
- ALMEIDA J.P.F.A.
- ALTIG R.
- ALTIG R.
- ALVES A.C.R.
- ANDRADE G.V.
- ASSIS J.S.
- BARBOSA V.N.
- BOKERMANN C.A.
- BOKERMANN W.C.A.
- BOKERMANN W.C.A.
- BOULENGER G.A.
- BREDER J.C.M.
- CAMPOS T.F.
- CARAMASCHI U.
- CARNAVAL C.A.O.Q.
- CARNEIRO M.C.L.
- CARVALHO-E-SILVA S.P.
- CARVALHO-E-SILVA S.P.
- CASAL F.C.
- CASCON P.
- CEI J. M.
- COSTA E.F.
- CRUZ C.A.G.
- CRUZ C.A.G.
- CRUZ C.A.G.
- Daniel Oliveira Mesquita
- DE SÁ R.O.
- Denise de Cerqueira Rossa-Feres
- DIXON JR.
- DUBEUX M.J.M.
- DUBEUX M.J.M.
- DUBEUX M.J.M.
- DUELLMAN W.E.
- DUELLMAN W.E.
- DUELLMAN W.E.
- FABREZI M.
- FAIVOVICH J.
- FAIVOVICH J.
- FATORELLI P.
- Felipe de Medeiros Magalhães
- Filipe Augusto Cavalcanti do Nascimento
- FROST D.R.
- GOMES M. R.
- GOMES M.R.
- GOMES M.R.
- GOSNER K.L.
- GROSJEAN S.
- HAAS A.
- HEDGES S.B.
- HERO J.M.
- HEYER W.R.
- HEYER W.R.
- Izabel Regina Soares da Silva
- João Paulo Felix Almeida
- JUNCÁ F.A.
- KENNY J.S.
- KOKUBUM M.N.C.
- KOKUBUM M.N.C.
- KOLENC F.
- LANTYER-SILVA A. S.
- Larissa Lima Correia
- LAUFER G.
- LAVILLA E.O.
- LAVILLA E.O.
- LEITE-FILHO E.
- LEON J.R.
- LESCURE J.
- LIPS K.R.
- LISBOA B.
- LISBOA B.S.
- LOEBMANN D.
- Luana Rodrigues Lima
- LUTZ B.
- LYNCH J.D.
- MACHADO I.F.
- MACIEL D.B.
- MAGALHÃES F.M.
- MAGALHÃES F.M.
- MAGALHÃES F.M.
- MAGALHÃES F.M.
- Marcos Jorge Matias Dubeux
- MCDIARMID R. W.
- MENIN M.
- MERCÊS E.A.
- MERCÊS E.A.
- MESQUITA D.O.
- MIJARES-URRUTIA A.
- MOURA G.J.B.
- NASCIMENTO F.A.C.
- NASCIMENTO F.A.C.
- NASCIMENTO F.A.C.
- NASCIMENTO F.A.C.
- NIEWKOOP P.D.
- OLIVEIRA F.F.
- OLIVEIRA M.I.R.R.
- PALMEIRA C.N.S.
- PEIXOTO O.L.
- PEIXOTO O.L.
- PEIXOTO O.L.
- PEIXOTO O.L.
- PEREIRA E.N.
- PEZZUTI T.L.
- PIMENTA B.
- POMBAL J.P.
- POMBAL JR. J.P.
- PRADO G.M.
- PROVETE D.B.
- PUGLIESE A.
- RADA-DE-MARTÍNEZ D.
- RIBEIRO M.C.
- ROBERTO I.J.
- ROBERTO I.J.
- ROBERTO I.J.
- RODRIGUES G.V.D.
- ROELANTS K.
- ROSSA-FERES D. C.
- ROSSA-FERES D.C.
- ROSSA-FERES D.C.
- ROSSA-FERES D.C.
- RUAS D.S.
- SANTANA D.O.
- SANTANA G.G.
- SANTANA G.G.
- SANTANA G.G.
- SANTOS D.L.
- SANTOS E.M.
- SANTOS E.M.
- SAVAGE J.M.
- SCHULZE A.
- SHERRATT E.
- SHERRATT E.
- SOBRINHO P.M.M.
- SOKOL O.M.
- STUDER A.
- Tamí Mott
- TOLLEDO J.
- Ubiratan Gonçalves
- VERDADE V.K.
- VIEIRA W. L. D. S.
- VIEIRA W.L.
- VIEIRA W.L.D.
- VILELA B.
- VIZOTTO L.D.
- WOGEL H.
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- 01/01/2020
- Field of study
New developments in vertebrate cytotaxonomy I. cytotaxonomy of the amphibians
- Author
- A. Barrio
- A. Barrio
- A. Barrio
- A. Barrio
- A. Barrio
- A. Morescalchi
- A. Morescalchi
- A. Morescalchi
- A. Morescalchi
- A. Morescalchi
- A. Morescalchi
- A. Morescalchi
- A. Morescalchi
- A. Morescalchi
- A. Morescalchi
- A. Morescalchi
- A. Morescalchi
- A.H. Sparrow
- A.N. Bhatnagar
- B.R. Seshachar
- B.R. Seshachar
- C.A. Bisbee
- C.H. Thiébaud
- C.J. Cole
- C.T. Baldari
- D.J. Haertel
- E. Olmo
- E. Olmo
- E. Olmo
- E. Olmo
- E.H. Taylor
- E.J. Lucca De
- E.M. Stephenson
- E.M. Stephenson
- G. Barsacchi
- G. Barsacchi-Pilone
- G. Barsacchi-Pilone
- G. Mancino
- G.L. Stebbins
- H. Szarski
- H. Wallace
- H.C. Macgregor
- H.C. Macgregor
- H.G. Callan
- I. Azumi
- I. Gilboa
- I. Nardi
- I.R.G. Ruiz
- J. Kezer
- J. Kezer
- J. Schmidtke
- J. Tymowska
- J. Tymowska
- J. Tymowska
- J. Tymowska
- J. Tymowska
- J. Weese de
- J.D. Lynch
- J.D. Lynch
- J.I. Menzies
- J.J. Scheel
- J.L. Edwards
- J.M. Savage
- J.P. Bogart
- J.P. Bogart
- J.P. Bogart
- J.P. Bogart
- J.P. Bogart
- J.P. Bogart
- J.P. Bogart
- J.P. Bogart
- J.R. Formas
- J.R. Formas
- J.S. Yadav
- K. Bachmann
- K. Bachmann
- K. Bachmann
- K.S. Thomson
- L. Singh
- L.A. Moffat
- M. Kuramoto
- M. Kuramoto
- M. Kuramoto
- M. Nishioka
- M. Vlad
- M.H. Wake
- M.J. Tyler
- M.K. Hecht
- M.K. Hecht
- M.L. Beçak
- N.A. Straus
- N.B. Elayidom
- O.G. Ward
- O.M. Sokol
- P.E. Leon
- P.E. Leon
- P.J. Pukkila
- R. Estes
- R.F. Batistic
- R.F. Laurent
- R.F. Laurent
- R.M.A. Blommers-Schlösser
- R.M.A. Blommers-Schlösser
- S. Mizuno
- S. Mizuno
- S. Ohno
- T. Seto
- V. Stingo
- W.P. Müller
- W.R. Heyer
- W.R. Heyer
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
The forward muon spectrometer of ALICE
- Author
- Abramova L.Y.
- Aggarwal M.M.
- Agnihotri A.
- Ahmad N.
- Ahmad T.
- Akhobadze K.G.
- Akimov V.A.
- Akindinov A.N.
- Akishin P.G.
- Alard J.P.
- Aleksandrov V.S.
- Alessandro B.
- Andersen E.
- Angelis A.
- Antinori F.
- Antonenko V.
- Antoniou N.
- Appelshauser H.
- Arefev V.A.
- Arkhipov E.
- Arnold L.
- Aslanoglou X.
- Astakhov V.I.
- Avakian R.
- Ayachi M.
- Aziz I.
- Baba P.V.K.S.
- Bachler J.
- Badyal S.K.
- Baldin A.
- Baldin A.
- Baldit A.
- Baratov V.M.
- Barlag C.
- Barres A.
- Bartenev V.
- Bartke J.
- Basmanov V.
- Bastid N.
- Batyunya B.V.
- Baur R.
- Bearden I.
- Beker H.
- Belikov Yu.A.
- Belyaev S.
- Beole S.
- Berset J.C.
- Berst J.D.
- Bhalla K.B.
- Bharti A.
- Bhasin A.
- Bhati A.K.
- Bhatia V.S.
- Bhattacharya P.
- Bimbot L.
- Blanchard G.
- Blinov N.A.
- Blonde J.P.
- Bloodworth I.J.
- Blume C.
- Bochek G.L.
- Bock R.
- Boggild H.
- Bohne E.
- Boldyshev V.F.
- Bolonin A.A.
- Bonazzola G.
- Bonvicini V.
- Boreiko V.
- Borisevich A.
- Borisovskaya Z.V.
- Bormann C.
- Borshchov V.N.
- Borzunov Yu.T.
- Bose S.
- Bosteels M.
- Botje M.
- Boyarinov S.V.
- Bracinik J.
- Brandolini F.
- Braun M.A.
- Braun-Munzinger P.
- Britton C.L.
- Brockmann R.
- Brossard M.
- Brun N.
- Brun R.
- Bryan W.L.
- Bucher D.
- Buijs A.
- Cai X.
- Caligiore C.
- Campbell M.
- Cantatore E.
- Carena Wisla
- Carlen L.
- Carney J.N.
- Carrer N.
- Castor J.
- Ceretto F.
- Cerny V.
- Ceru M.
- Chambon T.
- Chattopadhyay Subhasis
- Chattopadhyay Sukalyan
- Chervonny I.F.
- Chesi E.
- Chiavassa E.
- Christiansen J.
- Chumakov M.M.
- Cicalo C.
- Cina G.
- Claussen A.
- Coffin J.P.
- Colonna N.
- Comets M.P.
- Corsi F.
- Cosquer A.
- Csernai L.P.
- Cussonneau J.P.
- Datskov V.I.
- Daudo F.
- Daudon F.
- Davenport M.
- De Falco A.
- De Groot J.
- de Haas A.
- de los Heros C.
- De Marco N.
- De Venuto D.
- Dellacasa G.
- Demkin V.
- Denes Ervin
- Devaux A.
- Di Bari D.
- Di Ciano M.
- Di Liberto S.
- Di Mauro A.
- Divia R.
- Dobulevich V.M.
- Dodokhov V.Kh.
- Dorokhov V.V.
- Drancourt C.
- Drees A.
- Drobyshev G.
- Dubovik I.
- Dulinski W.
- Dupieux P.
- Dutta Majumdar M.R.
- Dzhavrishvili A.K.
- Dzhordzhadze V.
- Eckhardt F.
- Efimov L.G.
- Eganov V.
- El Chenawi K.
- Elia D.
- Engster C.
- Erazmus B.
- Ericson M.N.
- Eschke J.
- Espagnon B.
- Evans D.
- Fargeix J.
- Faschingbauer U.
- Fedorov V.M.
- Fedunov A.G.
- Feofilov G.A.
- Ferenc D.
- Filippov S.N.
- Fini R.A.
- Fintz P.
- Fischer H.
- Fodor Z.
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- Foka P.
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- Force P.
- Formenti F.
- Fraenkel Z.
- Friese V.
- Frolov A.R.
- Ftacnik J.
- Fuchs C.
- Fuchs M.
- Gaardhoje J.
- Gallio M.
- Ganti M.S.
- Garpman S.I.A.
- Gaudiot G.
- Gavrilov Yu.K.
- Gazdzicki M.
- Genolini B.
- Gerasimov S.
- Gevorkov L.D.
- Ghidini B.
- Giubellino P.
- Gladysz-Dziadus E.
- Glassel P.
- Godisov O.N.
- Golovanov L.
- Golubeva M.B.
- Golubeva T.A.
- Goncharov I.
- Goossens M.
- Goret B.
- Gornicki E.
- Gotra M.N.
- Gramegna G.
- Gregory C.
- Grella G.
- Grigalashvili N.
- Grigalashvili T.
- Grigorev V.
- Grigorian A.
- Grimaldi A.
- Grishuk Yu.G.
- Guber F.F.
- Guida M.
- Guillaume G.
- Guilloux G.
- Gulkanian H.
- Gunther J.
- Gupta A.
- Gupta S.
- Gupta V.
- Guskov B.N.
- Gustafsson H.A.
- Gutbrod H.H.
- Haider S.
- Hakobian R.
- Hansen O.
- Harangozo G.
- Hebrard L.
- Heijne E.
- Heitz C.
- Helstrup H.
- Herrera-Corral G.
- Hetland Kristin Fanebust
- Hlinka V.
- Holba A.
- Holme A.K.
- Hrivnacova I.
- Hu Y.
- Hu Y.
- Idzik M.
- Igolkin S.N.
- Ilkaev R.
- Innocenti P.G.
- Insolia A.
- Ioramashvili E.Sh.
- Ippolitov M.
- Irfan M.
- Irmscher D.
- Ivanov M.
- Jacholkowski A.
- Janik R.
- Jones G.T.
- Jouan D.
- Jovanovic P.
- Jundt F.
- Jung C.
- Jusko A.
- Kadyshevsky V.G.
- Kalechofsky H.
- Kalfas C.
- Kamermans R.
- Kaplin V.
- Kapogiannis A.
- Karadzhev K.
- Karavicheva T.L.
- Karpio K.
- Kats M.M.
- Keropian I.
- Kharadze A.V.
- Kharlov Yu.V.
- Kharzeev D.E.
- Khaustov G.V.
- Khizanishvili L.
- Khuskivadze T.V.
- Kinson J.B.
- Kiprich S.K.
- Kirk A.
- Kiselev S.M.
- Kiselev Yu.T.
- Kiselevich I.
- Kiss T.
- Klempt W.
- Klimenko E.
- Klovning A.
- Knudson K.
- Kolb B.
- Kolosov V.N.
- Kolozhvarii A.A.
- Komkov B.
- Komlev V.G.
- Kondratev O.
- Korolev V.
- Kosov M.
- Kovalenko A.D.
- Kowalski M.
- Kralik I.
- Krasulin A.
- Kugler A.
- Kuhn C.
- Kuijer P.G.
- Kuleshov S.V.
- Kulibaba V.I.
- Kumar V.
- Kurepin A.B.
- Kuznetsov V.
- Laptev V.D.
- Lassalle J.
- Lautridou P.
- Le Bornec Y.
- Lebedev A.L.
- Lebedev V.
- Lefevre F.
- Legrand J.
- LeGuay M.
- Leistam L.
- Lenkeit B.
- Lenti V.
- Lietava R.
- Linares E.
- Linin I.
- Lishin V.
- Listratenko O.M.
- Liu F.
- Liu L.
- Ljubicic A.
- Lo Presti D.
- Lobanov V.I.
- Lobko A.A.
- Loginov V.
- Lopatik A.
- Lourenco C.
- Lourens W.
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- Luhning J.
- Luptak M.
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- Lutz J.
- Lykasov G.
- Lynen U.
- Lyuboshits V.
- Maazouzi C.
- Macciotta-Serpi M.
- MacCormick M.
- Macowicz M.
- Maksimov A.N.
- Maland O.
- Malinowski H.
- Mamulashvili A.
- Mangotra L.
- Manko V.I.
- Manso F.
- Manzari V.
- Mares J.
- Martemyanov A.N.
- Martin L.
- Martin M.
- Martinska G.
- Marzari-Chiesa A.
- Marzocca C.
- Masera M.
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- Masoni A.
- Matyushevsky E.A.
- Mavromanolakis G.
- Mazza G.
- Mazzoni M.A.
- Meddi F.
- Meggyesi Z.
- Megrabian S.
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- 27/10/2010
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Final Amended Report on the Safety Assessment of Methylparaben, Ethylparaben, Propylparaben, Isopropylparaben, Butylparaben, Isobutylparaben, and Benzylparaben as used in Cosmetic Products
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