An exploratory study of consumer psychology using the process descriptive approach: a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University

Information chunking under Brand Name and the ability to predict attribute preference were investigated, using a simple paired comparisons test with an expected value decision criteria, and a behavioural search process. Subjects in condition one were presented with eight different product attributes (including Brand and Manufacturer's Name), while subjects in condition two were given only six different attributes (Brand and Manufacturer's Name were unavailable). Both groups completed a simple paired comparison test and two weeks later each subject was allowed to select product information, item by item, from an information displayboard corresponding to the experimental group to which they belonged. Evidence for the chunking of information under the guise of the Brand Name attribute was found - more information was sought when Brand Name was available than when it was not. It was also found that Brand Name information was accessed more than any other type of product information, and when this information was not available, attribute preferences changed and Cents/gram information was accessed most. This caused a change in product selection. Subjects were found to adopt a satisficing approach to the information search task, accessing only a small subset of the total available information, and only a subset of the attributes presented to them. The simple paired comparison test with its expected-value decision criteria accurately predicted the order of attribute selection in the behavioural search. The results suggest the existence of choice heuristics for consumer decision making as outlined by the information processing approach to consumer psychology

Royal succession and kingship among the Picts

When we consider the history of the Picts we are faced with the perennial challenge for the early medievalist of deciding whether the fragments of evidence which survive are representative of the reality of Pictish society, or whether they provide us with distortions, based on patterns of survival. This issue is as relevant to the subject of royal succession as it is to other aspects of Pictish history. The debate over whether the Picts practised a matrilineal system, with the son of the previous king's sister becoming the next king, or whether it was a patrilineal system, with the kingship generally passing through the male line, has dominated the discussion of Pictish succession. Until the 1980s, the matriliny thesis was virtually unquestioned, and accepted by scholars including F. T. Wainwright, Marjorie Anderson, and Isabel Henderson1. The bases for this view were the accounts of the Pictish settlement of northern Britain in Bede's ‘Ecclesiastical History of the English People’ and Irish texts written throughout the medieval period, but mainly surviving in versions from the twelfth century or later.2 In these sources it was claimed that the Picts went to Ireland before arriving in northern Britain, and that they obtained wives from the Irish, with some versions stating that this was done on condition that the succession went through the female line. Other sources which did not openly discuss the nature of Pictish succession, particularly the Irish chronicles and the Pictish king-lists, were then interpreted by scholars in relation to these accounts and were thought to support them

Genes Influencing Circadian Differences in Blood Pressure in Hypertensive Mice

Essential hypertension is a common multifactorial heritable condition in which increased sympathetic outflow from the central nervous system is involved in the elevation in blood pressure (BP), as well as the exaggerated morning surge in BP that is a risk factor for myocardial infarction and stroke in hypertensive patients. The Schlager BPH/2J mouse is a genetic model of hypertension in which increased sympathetic outflow from the hypothalamus has an important etiological role in the elevation of BP. Schlager hypertensive mice exhibit a large variation in BP between the active and inactive periods of the day, and also show a morning surge in BP. To investigate the genes responsible for the circadian variation in BP in hypertension, hypothalamic tissue was collected from BPH/2J and normotensive BPN/3J mice at the ‘peak’ (n = 12) and ‘trough’ (n = 6) of diurnal BP. Using Affymetrix GeneChip® Mouse Gene 1.0 ST Arrays, validation by quantitative real-time PCR and a statistical method that adjusted for clock genes, we identified 212 hypothalamic genes whose expression differed between ‘peak’ and ‘trough’ BP in the hypertensive strain. These included genes with known roles in BP regulation, such as vasopressin, oxytocin and thyrotropin releasing hormone, as well as genes not recognized previously as regulators of BP, including chemokine (C-C motif) ligand 19, hypocretin and zinc finger and BTB domain containing 16. Gene ontology analysis showed an enrichment of terms for inflammatory response, mitochondrial proton-transporting ATP synthase complex, structural constituent of ribosome, amongst others. In conclusion, we have identified genes whose expression differs between the peak and trough of 24-hour circadian BP in BPH/2J mice, pointing to mechanisms responsible for diurnal variation in BP. The findings may assist in the elucidation of the mechanism for the morning surge in BP in essential hypertension

Intratumoral IL-12 and TNF-α–Loaded Microspheres Lead To Regression of Breast Cancer and Systemic Antitumor Immunity

Background: Local, sustained delivery of cytokines at a tumor can enhance induction of antitumor immunity and may be a feasible neoadjuvant immunotherapy for breast cancer. We evaluated the ability of intratumoral poly-lactic-acid-encapsulated microspheres (PLAM) containing interleukin 12 (IL-12), tumor necrosis factor α (TNF-α), and granulocyte-macrophage colony stimulating factor (GM-CSF) in a murine model of breast cancer to generate a specific antitumor response.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/41401/1/10434_2004_Article_147.pd

Cohort profile : demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe

Purpose: The presence of distinct child and adolescent mental health services (CAMHS) and adult mental health services (AMHS) impacts continuity of mental health treatment for young people. However, we do not know the extent of discontinuity of care in Europe nor the effects of discontinuity on the mental health of young people. Current research is limited, as the majority of existing studies are retrospective, based on small samples or used non-standardised information from medical records. The MILESTONE prospective cohort study aims to examine associations between service use, mental health and other outcomes over 24 months, using information from self, parent and clinician reports. Participants: Seven hundred sixty-three young people from 39 CAMHS in 8 European countries, their parents and CAMHS clinicians who completed interviews and online questionnaires and were followed up for 2 years after reaching the upper age limit of the CAMHS they receive treatment at. Findings to date: This cohort profile describes the baseline characteristics of the MILESTONE cohort. The mental health of young people reaching the upper age limit of their CAMHS varied greatly in type and severity: 32.8% of young people reported clinical levels of self-reported problems and 18.6% were rated to be ‘markedly ill’, ‘severely ill’ or ‘among the most extremely ill’ by their clinician. Fifty-seven per cent of young people reported psychotropic medication use in the previous half year. Future plans: Analysis of longitudinal data from the MILESTONE cohort will be used to assess relationships between the demographic and clinical characteristics of young people reaching the upper age limit of their CAMHS and the type of care the young person uses over the next 2 years, such as whether the young person transitions to AMHS. At 2 years follow-up, the mental health outcomes of young people following different care pathways will be compared. Trial registration number: NCT03013595

The Húi Néill and the Leinstermen in the Annals of Ulster, 431-516 A.D.

Smyth Alfred P. The Húi Néill and the Leinstermen in the Annals of Ulster, 431-516 A.D.. In: Etudes Celtiques, vol. 14, fascicule 1, 1974. pp. 121-143