Thermodynamic properties of interstitial elements in the refractory metals Semiannual report, 1 Jun. - 1 Dec. 1966

Thermodynamic properties of interstitial elements in refractory metal

Ground state and vortex states of bosons in an anisotropic trap: A variational approach

We propose a simple variational form of the wave function to describe the ground state and vortex states of a system of weakly interacting Bose gas in an anisotropic trap. The proposed wave function is valid for a wide range of the particle numbers in the trap. It also works well in the case of attractive interaction between the atoms. Further, it provides an easy and fast method to calculate the physical quantities of interest. The results compare very well with those obtained by purely numerical techniques. Using our wave function we have been able to verify, for the first time, the predicted behaviour of aspect ratio.Comment: Revised version, To appear in the special issue of European Physical Journal

Crystallization of Simple Fluids: Relative Stability of f.c.c. and b.c.c Structures

A free-energy functional for a crystal that contains both the symmetry conserved and symmetry broken parts of the direct pair correlation function is developed. The free-energy functional is used to investigate the crystallization of fluids interacting via the inverse power potential ; $u(r)=\epsilon {(\sigma/r)}^n$. In agreement with simulation results we find that for $n=12$ the freezing is into close packed f.c.c structure while for soft repulsions $(n\leq 6)$ b.c.c phase is more stable.Comment: 9 pages, 2 figure

Tuberculosis vaccine: pipeline approaches and future prospective

Tuberculosis (TB), despite anti-mycobacterial therapies and vaccine, is a deadly infectious disease with about 12 million incident cases worldwide. Existing Bacillus Calmette-Guérin (BCG) vaccine is unquestionably inexpensive, safe and effective against severe forms of childhood TB but appears to be limited in effectiveness against adult pulmonary disease in endemic areas. Genetic variation in the population is the major obstruction inhibiting validation of biomarkers for protective human immunity against TB. Since current TB cases are presenting new challenges with threats of HIV co-infection therefore various attempts at a global platform are being made to develop a new modified vaccine against it. Consequently, Modified Vaccinia Ankara virus (MVA) vectored MPT64 & Ag85A delivery and polyvalent DNA vaccine, expressing an ESAT6–Ag85B fusion protein etc. are preclinically tested for boosted immune effects. However, better vaccine approaches still need to be developed against M. tuberculosis which can be unbeaten in most infected areas