237 research outputs found
Factors Affecting the Adoption of Cloud for Software Development: A Case from Turkey
Cloud-based solutions for software development activities have been emerging in the last decade. This study aims to develop a hybrid technology adoption model for cloud use in software development activities. It is based on Technology Acceptance Model (TAM), Technology–Organization–Environment (TOE) framework, and the proposed extension Personal–Organization–Project (POP) structure. The methodology selected is a questionnaire-based survey and data are collected through personally administered questionnaire sessions with developers and managers, resulting in 268 responses regarding 84 software development projects from 30 organizations in Turkey, selected by considering company and project sizes and geographical proximity to allow face-to-face response collection. Structural Equation Modeling (SEM) is used for statistical evaluation and hypothesis testing. The final model was reached upon modifications and it was found to explain the intention to adopt and use the cloud for software development meaningfully. To the best of our knowledge, this is the first study to identify and understand factors that affect the intention of developing software on the cloud. The developed hybrid model was validated to be used in further technology adoption studies. Upon modifying the conceptual model and discovering new relations, a novel model is proposed to draw the relationships between the identified factors and the actual use, intention to use and perceived suitability. Practical and social implications are drawn from the results to help organizations and individuals make decisions on cloud adoption for software development
Social Bayes: using Bayesian modeling to study autistic trait–related differences in social cognition - Retracted article
Background: Autism is characterized by impairments of social interaction, but the underlying subpersonal processes are still a matter of controversy. It has been suggested that the autistic spectrum might be characterized by alterations of the brain’s inference on the causes of socially relevant signals. However, it is unclear at what level of processing such trait-related alterations may occur.
Methods: We used a reward-based learning task that requires the integration of nonsocial and social cues in conjunction with computational modeling. Healthy subjects (N = 36) were selected based on their Autism Quotient Spectrum (AQ) score, and AQ scores were assessed for correlations with model parameters and task scores.
Results: Individual differences in AQ were inversely correlated with participants’ task scores (r = −.39, 95% confidence interval [CI] [−.68, −.13]). Moreover, AQ scores were significantly correlated with a social weighting parameter that indicated how strongly the decision was influenced by the social cue (r = −.42, 95% CI [−.66, −.19]), but not with other model parameters. Also, more pronounced social weighting was related to higher scores (r = .50, 95% CI [.20, .86]).
Conclusions: Our results demonstrate that higher autistic traits in healthy subjects are related to lower scores in a learning task that requires social cue integration. Computational modeling further demonstrates that these trait-related performance differences are not explained by an inability to process the social stimuli and its causes, but rather by the extent to which participants take into account social information during decision making
Crystal structure and Hirshfeld surface analysis of two 5,11-methanobenzo[g][1,2,4]triazolo[1,5 c][1,3,5]oxadiazocine derivatives
In the title compounds, 9-bromo-2,5-dimethyl-11,12-dihydro-5H-5,11-methanobenzo[g][1,2,4]triazolo[1,5-c][1,3,5]oxadiazocine, C13H13BrN4O (I), and 7-methoxy-5-methyl-2-(pyridin-4-yl)-11,12-dihydro-5H-5,11-methanobenzo[g][1,2,4]triazolo[1,5-c][1,3,5]oxadiazocine, C18H17N5O2 (II), the triazole ring is inclined to
the benzene ring by 85.15 (9) and 76.98 (5) in compounds I and II, respectively.
In II, the pyridine ring is almost coplanar with the triazole ring, having a dihedral
angle of 4.19 (8). In the crystal of I, pairs of N—HN hydrogen bonds link the
molecules to form inversion dimers with an R2
2
(8) ring motif. The dimers are
linked by C—H and C—Br interactions forming layers parallel to the bc
plane. In the crystal of II, molecules are linked by N—HN and C—HO
hydrogen bonds forming chains propagating along the b-axis direction. The
intermolecular interactions were investigated using Hirshfeld surface analysis
and two-dimensional fingerprint plots, and the molecular electrostatic potential
surface was also analysed. The Hirshfeld surface analysis of I suggests that the
most significant contributions to the crystal packing are HH (42.4%) and
OH/HO (17.9%) contacts. For compound II, the HH (48.5%), CH/
HC (19.6%) and NH/HN (16.9%) interactions are the most important
contributions.The authors acknowledge the Faculty of Arts and Sciences, Ondokuz Mayis University, Turkey, for the use of the Stoe IPDS 2 diffractometer (purchased under grant F. 279 of the University Research Fund) and the Council of Higher Education of Turkey, Mevlana Exchange Program (MEV-2016-027)
Enhanced self-collimation effect by low rotational symmetry in hexagonal lattice photonic crystals
In this study, we present the design of a photonic crystal (PC) structure
with a hexagonal lattice, where adjustments to the PC unit cell symmetry reveal
an all-angle self-collimation (SC) effect. By optimizing opto-geometric
parameters, such as the rotational angle of auxiliary rods and adjacent
distances, we analyze the SC property in detail, leveraging group velocity
dispersion (GVD) and third-order dispersion (TOD) characteristics. We also
investigate the relationship between symmetry properties and their influence on
dispersion characteristics. Through symmetry manipulation, we gain a
comprehensive understanding of the underlying mechanisms governing light
collimation and confinement in the proposed configurations. The PC structure
with a symmetry group exhibits all-angle SC effect within the range of
and normalized frequencies, with a
bandwidth of . Further breaking the symmetry,
transforming from to group symmetry, enhances the SC bandwidth to
and reveals the perfect linear equi-frequency
contours (EFC) at two different frequency bands: all angle SC between
and normalized frequencies in the 4th
transverse magnetic (TM) band and between and
in the 5th TM band. Additionally, we propose a
composite/hybrid PC structure resembling group symmetry, where two
auxiliary rods are replaced by rectangular photonic wires with the same
refractive index and width equal to the diameter of auxiliary rods. This hybrid
structure exhibits an all-angle SC effect with an operating bandwidth of
, displays near-zero GVD and TOD performance
and offers enhanced robustness against potential fabrication precision issues
The first clinical case due to AP92 like strain of Crimean-Congo Hemorrhagic Fever virus and a field survey
<p>Abstract</p> <p>Background</p> <p>Crimean-Congo Hemorrhagic Fever (CCHF) is a fatal infection, but no clinical case due to AP92 strain was reported. We described the first clinical case due to AP92 like CCHFV.</p> <p>Methods</p> <p>A case infected by a AP92 like CCHFV was detected in Balkanian part of Turkey. Diagnosis was confirmed by RT-PCR and sequencing. A human serologic and tick survey studies were performed in the region, where the case detected.</p> <p>Results</p> <p>Thirty eight individuals out of 741 were found to be anti CCHFV IgM positive. The attack rate for overall CCHFV was calculated as 5.2%. In univariate analyses, CCHFV IgM positivity was found to be associated with the age (p < 0.001), male gender (p = 0.001), agricultural activity (p = 0.036), and history of tick bite (p = 0.014). In multivariate analysis, older age (OR: 1.03, CI:1.01–1.05, p < 0.001), male gender were found to be the risk factors (OR: 2.5, CI:1.15–5.63, p = 0.020) for CCHFV infection.</p> <p>Conclusion</p> <p>This is the first human case with AP92 like CCHFV infection. Furthermore, this is the first report of AP92 like strain in Turkey. In the region, elderly males carry the highest risk for CCHFV infection.</p
Transdermal flux predictions for selected selective oestrogen receptor modulators (SERMs):Comparison with experimental results
The aim of this work was to evaluate the feasibility of delivering transdermally a series of highly lipophilic compounds (log P similar to 4-7), comprising several selective oestrogen receptor modulators and a modified testosterone (danazol). The maximum fluxes of the drugs were predicted theoretically using the modified Potts & Guy algorithm (to determine the permeability coefficient (k(p)) from water) and the calculated aqueous solubilities. The correction provided by Cleek & Bunge took into account the contribution of the viable epidermal barrier to the skin permeation of highly lipophilic compounds. Experimental measurements of drug fluxes from saturated hydroalcoholic solutions were determined in vitro through excised pig skin. Overall, the predicted fluxes were in good general agreement (within a factor of 10) with the experimental results. Most of the experimental fluxes were greater than those predicted theoretically suggesting that the 70:30 v/v ethanol-water vehicle employed may have had a modest skin penetration enhancement effect. This investigation shows that the transdermal fluxes of highly lipophilic compounds can be reasonably predicted from first principles provided that the viable epidermis, underlying the stratum corneum, is included as a potentially important contributor to the skin's overall barrier function. Furthermore, the absolute values of the measured fluxes, when considered in parallel with previous clinical studies, indicate that it might be feasible to topically deliver a therapeutically useful amount of some of the compounds considered to treat cancerous breast tissue. (C) 2013 Elsevier B.V. All rights reserved
- …