38 research outputs found
Appunti sul concordato preventivo dopo la legge di conversione del D.L. N. 83/2015
Il saggio esamina le novitĂ piĂą rilevanti in materia di concordato preventivo introdotte dalla legge di conversione del d.l. n. 83/2015, soffermandosi in particolare sul "favor" manifestato dal legislatore in materia di concordato con continuitĂ aziendale
The Assessment of the Public and Private Conveniences in the Urban Transformation Interventions: An Optimization Model for the Value Recapture Adoption
In the field of urban transformation interventions, the “privatization” of the potential indirect benefits is
a crucial issue. In fact, if not adequately recaptured and managed they can favor the private developers or owners
by reducing the share of acquirable public resources intended for the realization of new infrastructures and services.
For this reason, the Extraordinary Urbanization Contribution (EUC) was introduced in Italy in 2014 with Art. 16,
co.4 of DPR n. 380/2001 to allow an equitable redistribution - between the public and private subjects involved - of
the surplus value generated by urban variant interventions. The lack of univocal guidance for determining this
contribution has made its application difficult, therefore the work aims to provide a rational and methodological
rigorous decision support model intended for the public administration for assessing the surplus value generated by
complex urban variant intervention. Its methodological structure is based on goal programming optimization
principles. In particular, the innovative contribution of the model is to provide the assessment of the surplus value
of “complex” urban variant interventions, or those for which the inclusion of the “time” factor could affect the
results and the conveniences of the parties involved. For these reasons, different discount rate values are assumed.
The main findings regard the possibility of being used for supporting the public administrations in the correct
application of the national regulations, also consistent with the value recapture and value sharing research streams,
and for identifying the extra-profit margins and conveniences of the private subject involved
Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis
Importance: Juvenile amyotrophic lateral sclerosis (ALS) is a rare form of ALS characterized by age of symptom onset less than 25 years and a variable presentation.Objective: To identify the genetic variants associated with juvenile ALS.Design, Setting, and Participants: In this multicenter family-based genetic study, trio whole-exome sequencing was performed to identify the disease-associated gene in a case series of unrelated patients diagnosed with juvenile ALS and severe growth retardation. The patients and their family members were enrolled at academic hospitals and a government research facility between March 1, 2016, and March 13, 2020, and were observed until October 1, 2020. Whole-exome sequencing was also performed in a series of patients with juvenile ALS. A total of 66 patients with juvenile ALS and 6258 adult patients with ALS participated in the study. Patients were selected for the study based on their diagnosis, and all eligible participants were enrolled in the study. None of the participants had a family history of neurological disorders, suggesting de novo variants as the underlying genetic mechanism.Main Outcomes and Measures: De novo variants present only in the index case and not in unaffected family members.Results: Trio whole-exome sequencing was performed in 3 patients diagnosed with juvenile ALS and their parents. An additional 63 patients with juvenile ALS and 6258 adult patients with ALS were subsequently screened for variants in the SPTLC1 gene. De novo variants in SPTLC1 (p.Ala20Ser in 2 patients and p.Ser331Tyr in 1 patient) were identified in 3 unrelated patients diagnosed with juvenile ALS and failure to thrive. A fourth variant (p.Leu39del) was identified in a patient with juvenile ALS where parental DNA was unavailable. Variants in this gene have been previously shown to be associated with autosomal-dominant hereditary sensory autonomic neuropathy, type 1A, by disrupting an essential enzyme complex in the sphingolipid synthesis pathway.Conclusions and Relevance: These data broaden the phenotype associated with SPTLC1 and suggest that patients presenting with juvenile ALS should be screened for variants in this gene.</p
Profili genetici del concordato fallimentare
Il saggio delinea gli aspetti strutturali del concordato fallimentare nella prima versione disciplinata dalla legge di riforma, soffermandosi sulla individuazione dei soggetti legittimati a formulare la proposta,sui termini e sul contenuto di questa. Particolare attenzione viene dedicata alla formazione delle classi ed alla situazione dei creditori muniti di prelazione, nonché all’ipotesi del concorso di proposte nella fase dell’approvazione del concordato
Ammissibilità della trasformazione di un’impresa individuale in s.r.l. e decorso del termine di fallibilità dell’impresa cessata
Il saggio affronta la controversa questione della trasformazione dell'impresa individuale in società , ancorché unipersonale, e del decorso del termine di fallibilità dell'impresa cessata
La Cassazione precisa la nozione di «consumatore» ai fini dell’accesso al procedimento riservato di composizione delle crisi da sovraindebitamento
Il saggio commenta criticamente una pronunzia della Suprema Corte, che, prendendo posizione per la prima volta, sulle caratteristiche del "consumatore", ai sensi della l.n. 3/2012, afferma che tale deve essere considerato anche la persona fisica, che sia anche imprenditore o professionista, qualora la situazione
di sovraindebitamento può proporre un piano del consumatore ai sensi della l.n. 3/2012, a condizione che la situazione di sovraindebitamento sia causata in via esclusiva da debiti di natura consumeristica