15 research outputs found
Rapid detection and identification of pathogens in critically ill and immunocompromised hosts using molecular techniques
No full textWide Distribution and Genetic Diversity of “Candidatus Neoehrlichia mikurensis” in Rodents from China
No full textCHARACTERIZATION OF THE RARE TRANSLOCATION T(3;10)(Q26;Q21) IN AN ACUTE MYELOID LEUKEMIA PATIENT
No full textMolecular variability of FLT3/ITD mutants and their impact on the differentiation program of 32D cells: Implications for the biological properties of AML blasts
No full textFLT3 is the most frequently mutated gene in acute myeloid leukemia (AML), with internal tandem duplications (ITDs) accounting for up to 30% of its mutations. To analyze the impact of individual ITDs on the expression profile of immature myeloid cells, we have established 32D cell lines expressing nine different FLT3/ITDs isolated from AML patients and subjected them to whole genome expression profiling and 2DE/LC/MS proteomics. Our data indicate that in comparison to the controls, FLT3/ITD-positive 32D cells exhibit less mature expression profiles resembling early hematopoietic progenitors. Moreover, our results suggest that there exist biological differences among individual ITD variants. (c) 2009 Elsevier Ltd. All rights reserved
Infections With the Tick-Borne Bacterium "Candidatus Neoehrlichia mikurensis" Mimic Noninfectious Conditions in Patients With B Cell Malignancies or Autoimmune Diseases
No full textA Novel High-Resolution Melt PCR Assay Discriminates Anaplasma phagocytophilum and “Candidatus Neoehrlichia mikurensis”
No full textMultilocus Sequence Analysis of Clinical “Candidatus Neoehrlichia mikurensis” Strains from Europe
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