460,277 research outputs found

    High voltage transistor circuit Patent

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    High voltage transistor circui

    Bioaffinity detection of pathogens on surfaces

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    The demand for improved technologies capable of rapidly detecting pathogens with high sensitivity and selectivity in complex environments continues to be a significant challenge that helps drive the development of new analytical techniques. Surface-based detection platforms are particularly attractive as multiple bioaffinity interactions between different targets and corresponding probe molecules can be monitored simultaneously in a single measurement. Furthermore, the possibilities for developing new signal transduction mechanisms alongside novel signal amplification strategies aremuchmore varied. In this article, we describe some of the latest advances in the use of surface bioaffinity detection of pathogens. Three major sections will be discussed: (i) a brief overview on the choice of probe molecules such as antibodies, proteins and aptamers specific to pathogens and surface attachment chemistries to immobilize those probes onto various substrates, (ii) highlighting examples among the current generation of surface biosensors, and (iii) exploring emerging technologies that are highly promising and likely to form the basis of the next generation of pathogenic sensors

    Communication, coordination and networks

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    We study experimentally how the network structure and length of pre-play communication affect behavior and outcome in a multi-player coordination game with conflicting preferences. Network structure matters but the interaction between network and time effects is more subtle. Under each time treatment, substantial variations are observed in both the rate of coordination and distribution of coordinated outcomes across networks. But, increasing the communication length improves both efficiency and equity of coordination. In all treatments, coordination is mostly explained by convergence in communication. We also identify behaviors that explain variations in the distribution of coordinated outcomes both within and across networks

    Effect of Diethylenetriamine and Triethylamine sensitization on the critical diameter of Nitromethane

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    In this work, the critical diameter for detonation was measured for Nitromethane (NM) sensitized with two different amines: Diethylenetriamine (DETA) and Triethylamine (TEA). The critical diameter in glass and polyvinylchloride tubes is found to decrease rapidly as the amount of sensitizer is increased, then increase past a critical amount of sensitizer. Thus the critical diameter reaches a minimum at a critical concentration of sensitizer. It was also found that the critical diameter is lower with DETA than with TEA

    Thermal Model and Optimization of a Large Crystal Detector using a Metallic Magnetic Calorimeter

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    We established a simple thermal model of the heat flow in a large crystal detector designed for a neutrinoless double beta decay experiment. The detector is composed of a CaMoO4_{4} crystal and a metallic magnetic calorimeter (MMC). The thermal connection between the absorber and the sensor consists of a gold film evaporated on the crystal surface and gold bonding wires attached to this film and the MMC sensor. The model describes athermal and thermal processes of heat flow to the gold film. A successive experiment based on optimization calculations of the area and thickness of the gold film showed a significant improvement in the size and rise-time of the measured signals

    Zero-temperature resistive transition in Josephson-junction arrays at irrational frustration

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    We use a driven Monte Carlo dynamics in the phase representation to determine the linear resistivity and current-voltage scaling of a two-dimensional Josephson-junction array at an irrational flux quantum per plaquette. The results are consistent with a phase-coherence transition scenario where the critical temperature vanishes. The linear resistivity is nonzero at any finite temperatures but nonlinear behavior sets in at a temperature-dependent crossover current determined by the thermal critical exponent. From a dynamic scaling analysis we determine this critical exponent and the thermally activated behavior of the linear resistivity. The results are in agreement with earlier calculations using the resistively shunted-junction model for the dynamics of the array. The linear resistivity behavior is consistent with some experimental results on arrays of superconducting grains but not on wire networks, which we argue have been obtained in a current regime above the crossover current.Comment: 7 pages, 5 figures, to appear in Phys. Rev.

    c-axis Raman Scattering in MgB2: Observation of a Dirty-Limit Gap in the pi-bands

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    Raman scattering spectra from the ac-face of thick MgB2 single crystals were measured in zz, xz and xx polarisations. In zz and xz polarisations a threshold at around 29 cm^{-1} forms in the below Tc continuum but no pair-breaking peak is seen, in contrast to the sharp pair-breaking peak at around 100 cm^{-1} seen in xx polarisation. The zz and xz spectra are consistent with Raman scattering from a dirty superconductor while the sharp peak in the xx spectra argues for a clean system. Analysis of the spectra resolves this contradiction, placing the larger and smaller gap magnitudes in the sigma and pi bands, and indicating that relatively strong impurity scattering is restricted to the pi bands.Comment: Revised manuscript accepted for publication in Physical Review Letter

    Shock and vibration response of multistage structure

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    Study of the shock and vibration response of a multistage structure employed analytically, lumped-mass, continuous-beam, multimode, and matrix-iteration methods. The study was made on the load paths, transmissibility, and attenuation properties along a longitudinal axis of a long, slender structure with increasing degree of complexity
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