Stochastic differential equation involving Wiener process and fractional Brownian motion with Hurst index H>1/2H> 1/2

We consider a mixed stochastic differential equation driven by possibly dependent fractional Brownian motion and Brownian motion. Under mild regularity assumptions on the coefficients, it is proved that the equation has a unique solution

Loss of correlation between HIV viral load and CD4+ T-cell counts in HIV/HTLV-1 co-infection in treatment naive Mozambican patients

Seven hundred and four HIV-1/2-positive, antiretroviral therapy (ART) naïve patients were screened for HTLV-1 infection. Antibodies to HTLV-1 were found in 32/704 (4.5%) of the patients. Each co-infected individual was matched with two HIV mono-infected patients according to World Health Organization clinical stage, age +/-5 years and gender. Key clinical and laboratory characteristics were compared between the two groups. Mono-infected and co-infected patients displayed similar clinical characteristics. However, co-infected patients had higher absolute CD4+ T-cell counts (P = 0.001), higher percentage CD4+ T-cell counts (P < 0.001) and higher CD4/CD8 ratios (P < 0.001). Although HIV plasma RNA viral loads were inversely correlated with CD4+ T-cell-counts in mono-infected patients (P < 0.0001), a correlation was not found in co-infected individuals (P = 0.11). Patients with untreated HIV and HTLV-1 co-infection show a dissociation between immunological and HIV virological markers. Current recommendations for initiating ART and chemoprophylaxis against opportunistic infections in resource-poor settings rely on more readily available CD4+ T-cell counts without viral load parameters. These guidelines are not appropriate for co-infected individuals in whom high CD4+ T-cell counts persist despite high HIV viral load states. Thus, for co-infected patients, even in resource-poor settings, HIV viral loads are likely to contribute information crucial for the appropriate timing of ART introduction

Random Walk with Shrinking Steps: First Passage Characteristics

We study the mean first passage time of a one-dimensional random walker with step sizes decaying exponentially in discrete time. That is step sizes go like $\lambda^{n}$ with $\lambda\leq1$ . We also present, for pedagogical purposes, a continuum system with a diffusion constant decaying exponentially in continuous time. Qualitatively both systems are alike in their global properties. However, the discrete case shows very rich mathematical structure, depending on the value of the shrinking parameter, such as self-repetitive and fractal-like structure for the first passage characteristics. The results we present show that the most important quantitative behavior of the discrete case is that the support of the distribution function evolves in time in a rather complicated way in contrast to the time independent lattice structure of the ordinary random walker. We also show that there are critical values of $\lambda$ defined by the equation $\lambda^{K}+2\lambda^{P}-2=0$ with $\{K,N\}\in{\mathcal N}$ where the mean first passage time undergo transitions.Comment: Major Re-Editing of the article. Conclusions unaltere

Constrained Willmore Surfaces

Constrained Willmore surfaces are conformal immersions of Riemann surfaces that are critical points of the Willmore energy $W=\int H^2$ under compactly supported infinitesimal conformal variations. Examples include all constant mean curvature surfaces in space forms. In this paper we investigate more generally the critical points of arbitrary geometric functionals on the space of immersions under the constraint that the admissible variations infinitesimally preserve the conformal structure. Besides constrained Willmore surfaces we discuss in some detail examples of constrained minimal and volume critical surfaces, the critical points of the area and enclosed volume functional under the conformal constraint.Comment: 17 pages, 8 figures; v2: Hopf tori added as an example, minor changes in presentation, numbering changed; v3: new abstract and appendix, several changes in presentatio

Counting matrices over finite fields with support on skew Young diagrams and complements of Rothe diagrams

We consider the problem of finding the number of matrices over a finite field with a certain rank and with support that avoids a subset of the entries. These matrices are a q-analogue of permutations with restricted positions (i.e., rook placements). For general sets of entries these numbers of matrices are not polynomials in q (Stembridge 98); however, when the set of entries is a Young diagram, the numbers, up to a power of q-1, are polynomials with nonnegative coefficients (Haglund 98). In this paper, we give a number of conditions under which these numbers are polynomials in q, or even polynomials with nonnegative integer coefficients. We extend Haglund's result to complements of skew Young diagrams, and we apply this result to the case when the set of entries is the Rothe diagram of a permutation. In particular, we give a necessary and sufficient condition on the permutation for its Rothe diagram to be the complement of a skew Young diagram up to rearrangement of rows and columns. We end by giving conjectures connecting invertible matrices whose support avoids a Rothe diagram and Poincar\'e polynomials of the strong Bruhat order.Comment: 24 pages, 9 figures, 1 tabl

Normal Ordering for Deformed Boson Operators and Operator-valued Deformed Stirling Numbers

The normal ordering formulae for powers of the boson number operator $\hat{n}$ are extended to deformed bosons. It is found that for the `M-type' deformed bosons, which satisfy $a a^{\dagger} - q a^{\dagger} a = 1$, the extension involves a set of deformed Stirling numbers which replace the Stirling numbers occurring in the conventional case. On the other hand, the deformed Stirling numbers which have to be introduced in the case of the `P-type' deformed bosons, which satisfy $a a^{\dagger} - q a^{\dagger} a = q^{-\hat{n}}$, are found to depend on the operator $\hat{n}$. This distinction between the two types of deformed bosons is in harmony with earlier observations made in the context of a study of the extended Campbell-Baker-Hausdorff formula.Comment: 14 pages, Latex fil

Golden gaskets: variations on the Sierpi\'nski sieve

We consider the iterated function systems (IFSs) that consist of three general similitudes in the plane with centres at three non-collinear points, and with a common contraction factor \la\in(0,1). As is well known, for \la=1/2 the invariant set, \S_\la, is a fractal called the Sierpi\'nski sieve, and for \la<1/2 it is also a fractal. Our goal is to study \S_\la for this IFS for 1/2<\la<2/3, i.e., when there are "overlaps" in \S_\la as well as "holes". In this introductory paper we show that despite the overlaps (i.e., the Open Set Condition breaking down completely), the attractor can still be a totally self-similar fractal, although this happens only for a very special family of algebraic \la's (so-called "multinacci numbers"). We evaluate \dim_H(\S_\la) for these special values by showing that \S_\la is essentially the attractor for an infinite IFS which does satisfy the Open Set Condition. We also show that the set of points in the attractor with a unique ``address'' is self-similar, and compute its dimension. For ``non-multinacci'' values of \la we show that if \la is close to 2/3, then \S_\la has a nonempty interior and that if \la<1/\sqrt{3} then \S_\la$ has zero Lebesgue measure. Finally we discuss higher-dimensional analogues of the model in question.Comment: 27 pages, 10 figure

Towards a unified theory of Sobolev inequalities

We discuss our work on pointwise inequalities for the gradient which are connected with the isoperimetric profile associated to a given geometry. We show how they can be used to unify certain aspects of the theory of Sobolev inequalities. In particular, we discuss our recent papers on fractional order inequalities, Coulhon type inequalities, transference and dimensionless inequalities and our forthcoming work on sharp higher order Sobolev inequalities that can be obtained by iteration.Comment: 39 pages, made some changes to section 1

Operator renewal theory and mixing rates for dynamical systems with infinite measure

We develop a theory of operator renewal sequences in the context of infinite ergodic theory. For large classes of dynamical systems preserving an infinite measure, we determine the asymptotic behaviour of iterates $L^n$ of the transfer operator. This was previously an intractable problem. Examples of systems covered by our results include (i) parabolic rational maps of the complex plane and (ii) (not necessarily Markovian) nonuniformly expanding interval maps with indifferent fixed points. In addition, we give a particularly simple proof of pointwise dual ergodicity (asymptotic behaviour of $\sum_{j=1}^nL^j$) for the class of systems under consideration. In certain situations, including Pomeau-Manneville intermittency maps, we obtain higher order expansions for $L^n$ and rates of mixing. Also, we obtain error estimates in the associated Dynkin-Lamperti arcsine laws.Comment: Preprint, August 2010. Revised August 2011. After publication, a minor error was pointed out by Kautzsch et al, arXiv:1404.5857. The updated version includes minor corrections in Sections 10 and 11, and corresponding modifications of certain statements in Section 1. All main results are unaffected. In particular, Sections 2-9 are unchanged from the published versio