15,175 research outputs found
Cavitation-induced force transition in confined viscous liquids under traction
We perform traction experiments on simple liquids highly confined between
parallel plates. At small separation rates, we observe a simple response
corresponding to a convergent Poiseuille flow. Dramatic changes in the force
response occur at high separation rates, with the appearance of a force plateau
followed by an abrupt drop. By direct observation in the course of the
experiment, we show that cavitation accounts for these features which are
reminiscent of the utmost complex behavior of adhesive films under traction.
Surprisingly enough, this is observed here in purely viscous fluids.Comment: Submitted to Physical Review Letters on May 31, 2002. Related
informations on http://www.crpp.u-bordeaux.fr/tack.htm
A migrating epithelial monolayer flows like a Maxwell viscoelastic liquid
We perform a bidimensional Stokes experiment in an active cellular material:
an autonomously migrating monolayer of Madin-Darby Canine Kidney (MDCK)
epithelial cells flows around a circular obstacle within a long and narrow
channel, involving an interplay between cell shape changes and neighbour
rearrangements. Based on image analysis of tissue flow and coarse-grained cell
anisotropy, we determine the tissue strain rate, cell deformation and
rearrangement rate fields, which are spatially heterogeneous. We find that the
cell deformation and rearrangement rate fields correlate strongly, which is
compatible with a Maxwell viscoelastic liquid behaviour (and not with a
Kelvin-Voigt viscoelastic solid behaviour). The value of the associated
relaxation time is measured as ~min, is observed to be
independent of obstacle size and division rate, and is increased by inhibiting
myosin activity. In this experiment, the monolayer behaves as a flowing
material with a Weissenberg number close to one which shows that both elastic
and viscous effects can have comparable contributions in the process of
collective cell migration.Comment: 17 pages, 15 figure
Lagrange-Poincare field equations
The Lagrange-Poincare equations of classical mechanics are cast into a field
theoretic context together with their associated constrained variational
principle. An integrability/reconstruction condition is established that
relates solutions of the original problem with those of the reduced problem.
The Kelvin-Noether theorem is formulated in this context. Applications to the
isoperimetric problem, the Skyrme model for meson interaction, metamorphosis
image dynamics, and molecular strands illustrate various aspects of the theory.Comment: Submitted to Journal of Geometry and Physics, 45 pages, 1 figur
Criterion for purely elastic Taylor-Couette instability in the flows of shear-banding fluids
In the past twenty years, shear-banding flows have been probed by various
techniques, such as rheometry, velocimetry and flow birefringence. In micellar
solutions, many of the data collected exhibit unexplained spatio-temporal
fluctuations. Recently, it has been suggested that those fluctuations originate
from a purely elastic instability of the flow. In cylindrical Couette geometry,
the instability is reminiscent of the Taylor-like instability observed in
viscoelastic polymer solutions. In this letter, we describe how the criterion
for purely elastic Taylor-Couette instability should be adapted to
shear-banding flows. We derive three categories of shear-banding flows with
curved streamlines, depending on their stability.Comment: 6 pages, 3 figure
Potential "ways of thinking" about the shear-banding phenomenon
Shear-banding is a curious but ubiquitous phenomenon occurring in soft
matter. The phenomenological similarities between the shear-banding transition
and phase transitions has pushed some researchers to adopt a 'thermodynamical'
approach, in opposition to the more classical 'mechanical' approach to fluid
flows. In this heuristic review, we describe why the apparent dichotomy between
those approaches has slowly faded away over the years. To support our
discussion, we give an overview of different interpretations of a single
equation, the diffusive Johnson-Segalman (dJS) equation, in the context of
shear-banding. We restrict ourselves to dJS, but we show that the equation can
be written in various equivalent forms usually associated with opposite
approaches. We first review briefly the origin of the dJS model and its initial
rheological interpretation in the context of shear-banding. Then we describe
the analogy between dJS and reaction-diffusion equations. In the case of
anisotropic diffusion, we show how the dJS governing equations for steady shear
flow are analogous to the equations of the dynamics of a particle in a quartic
potential. Going beyond the existing literature, we then draw on the Lagrangian
formalism to describe how the boundary conditions can have a key impact on the
banding state. Finally, we reinterpret the dJS equation again and we show that
a rigorous effective free energy can be constructed, in the spirit of early
thermodynamic interpretations or in terms of more recent approaches exploiting
the language of irreversible thermodynamics.Comment: 14 pages, 6 figures, tutorial revie
Molekulare Signalwege der aseptischen Endoprothesenlockerung (Molecular pathways in aseptic loosening of orthopaedic endoprosthesis)
Abstract Operative joint replacement to treat disabling joint conditions secondary to degenerative and inflammatory arthritides has become one of the most efficacious and cost-effective procedures to relieve pain and restore joint function. However, prosthetic implants are not built to last forever and osteolysis and aseptic loosening has been associated with prosthetic arthroplasties since their introduction. The functional life of a synthetic joint is influenced by many factors including the material of the implant, operation procedures and the surgeon involved, as well as patient-related factors. Although promising developments have been achieved in this field, more than 10% of all implants still have to undergo operative revision within 15 years after the initial operation. Failure due to sepsis, fractures and dislocations has become rare; premature loosening of implants on the other hand is becoming much more important. Prosthetic loosening without concurrent infection or trauma is called aseptic loosening. It is generally accepted that small particles ("wear debris") and activated macrophages play a key role in aseptic loosening. The pathophysiology of this condition, however, is still not very well characterized. In this article, we review the molecular mechanisms and signal pathways that were unravelled as responsible factors for loosening orthopaedic implants. Finally, we discuss possible novel strategies for future therapeutic approaches
Infection levels and species diversity of ascaridoid nematodes in Atlantic cod, Gadus morhua, are correlated with geographic area and fish size
Atlantic cod (Gadus morhua) is among the most important commercial fish species on the world market. Its
infection by ascaridoid nematodes has long been known, Pseudoterranova even being named cod worm. In the
present study, 755 individuals were sampled in the Barents, Baltic and North Seas during 2012–2014.
Prevalences for Anisakis in whole fish and in fillets in the different fishing areas varied from 16 to 100% and
from 12 to 90% respectively. Abundance was also greatly influenced by the sampling area. Generalized additive
model results indicate higher numbers of Anisakis in the North Sea, even after the larger body size was accounted
for. Numbers and prevalence of Anisakis were positively related to fish length or weight. The prevalence of
parasites in whole fish and in fillets was also influenced by the season, with the spring displaying a peak for the
prevalence in whole fish and, at the same time, a drop for the prevalence in fillets. Whereas 46% of cod had
Anisakis larvae in their fillets, the majority (39%) had parasites mainly in the ventral part of the fillet and only
12% had parasites in their dorsal part. This observation is of importance for the processing of the fish. Indeed,
the trimming of the ventral part of the cod fillet would allow the almost total elimination of ascaridoids except
for cod from the Baltic Sea where there was no difference between the dorsal and the ventral part.
The presence of other ascaridoid genera was also noticeable in some areas. For Pseudoterranova, the highest
prevalence (45%) in whole fish was observed in the Northern North Sea, whereas the other areas had prevalences between 3 and 16%. Contracaecum was present in every commercial size cod sampled in the Baltic Sea
with an intensity of up to 96 worms but no Contracaecum was isolated from the Central North Sea. Non-zoonotic
Hysterothylacium was absent from the Baltic Sea but with a prevalence of 83% in the Barents and the Northern
North Sea.
A subsample of worms was identified with genetic-molecular tools and assigned to the species A. simplex (s.s.),
A. pegreffii, P. decipiens (s.s.), P. krabbei, C. osculatum and H. aduncum. In addition to high prevalence and
abundance values, the cod sampled in this study presented a diversity of ascaridoid nematodes with a majority of
fish displaying a co-infection. Out of 295 whole infected fish, 269 were co-infected by at least 2 genera
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