7,295 research outputs found

    On the categories of L-Valued and Q-Valued 6 deterministic fuzzy automata

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    Automata and languages have been studied in the context of different lattice structures by several authors. This paper is toward the categorical study of deterministic lattice-valued (L-valued) fuzzy automata and deterministic quantale-valued (Q-valued) fuzzy automata. The existence of initial and final objects in the subcategory of category of deterministic lattice-valued fuzzy automata is shown. We also show that there is an adjunction between the category of deterministic lattice-valued and quantale-valued fuzzy automata

    EMULSOMES FOR LIPOPHILIC ANTICANCER DRUG DELIVERY: DEVELOPMENT, OPTIMIZATION AND IN VITRO DRUG RELEASE KINETIC STUDY

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    Objective: The objective of the present study was to formulate and characterize paclitaxel (Ptx) loaded sterically stabilized emulsomes to provide non-toxic and biocompatible carriers with high Ptx loading efficiency. Methods: Plain (P-Es) and sterically stabilized emulsomes (SS-Es) were prepared by a modified solvent evaporation method using tristearin as solid lipid and optimized for lipid to (DSPC+CHOL+DSPE-PEG)/ tristearin ratio, lipid/lipid-PEG (DSPC+CHOL/DSPE-PEG) molar ratio, solid lipid concentration, phospholipid concentration, organic to aqueous phase volume and homogenization time based on their effect particle size and entrapment efficiency. Optimized emulsomes were characterized for morphological features, in vitro drug release kinetics and protection from plasma protein. Results: The emulsomes so formed were uniform in size with a mean particle diameter of 275±5.52 and 195±6.4 nm for P-Es and SS-Es respectively. All the formulations showed pH dependent drug release with a slow and sustained release profile. Slower drug release was observed from sterically stabilized emulsomes than the plain emulsomes. The drug release profile followed the Higuchi model with the Fickian diffusion pattern. The Pegylation of emulsomes significantly reduced the in vitro protein absorption. Conclusion: The sterically stabilized emulsome can serve as a novel non-toxic platform with longer circulatory time for the delivery of Paclitaxel and other poorly water-soluble drugs as well

    Potential use of cyanobacterial species in bioremediation of industrial effluents

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    This study investigated the potential degradation of industrial effluents by environmental species of cyanobacteria. Cyanobacterial species isolated from the Pharmaceutical and Textile industries Mandideep, Bhopal were exposed. Isolation and utilization of the locally generated cyanobacterial biomass for remediation of private industrial activities will generate a source of revenue in Bhopal localities. Biodegradation and biosorption capacity of some potential cyanobacterial species: Oscillatoria sp., Synechococcus sp., Nodularia sp., Nostoc sp. and Cyanothece sp. dominated the effluents and mixed cultures showed varying sensitivity. Contaminant was removed by all the species, either as individuals or mixtures, at both concentrations. The abundance of cyanobacteria in thiseffluent was due to favorable contents of organic matter, rich calcium and nutrients such as nitrates and phosphates with less dissolved oxygen. Removal efficiencies of the different contaminants were evaluated and compared. Results confirmed the high efficiencies of the investigated species for the removal of the target contaminants which were species and contaminant-dependent. The contaminants removal efficiency (RE) percentage of cyanobacterial species ranged between 69.5 and 99.6% with a maximum of 97.0 to 99.6% at 5 ppm, 83.9% and 99.7% at 10 ppm and maximum between 95.5 and 99.7%. Mixed culture RE percentages ranged between 91.6 and 100% at 5 ppm with a maximum range of 99.3 to 100%, while at 10 ppm, the RE percentage ranged between 90.4 and 100%, with a maximum range of 96.0 to 100%. Results indicate the potential of natural resources as efficient agents for pollution control.Key word: Cyanobacteria, industrial effluents, bioremediation

    Sexual reproduction of yellow ecotype of Neurospora intermedia in nature

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    The vegetative stage of yellow ecotype of Neurospora intermedia occurs on various substrates but there has been no evidence of its telomorphic stage in nature. This paper presents evidence for the sexual reproduction of this ecotype in nature on maize cobs

    Study of CMEs Associated Intense Geomagnetic Storms Observed During Solar Maximum 1989-1991

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    Investigation on the Performance of UPQC-Q for Voltage Sag Mitigation and PQ Improvement at a Critical Load Point

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    The unified power quality conditioner (UPQC) is one of the major custom power solutions, which is capable of mitigating the effect of supply voltage sag at the load end or at the point of common coupling (PCC) in a distributed network. It also prevents the propagation of the load current harmonics to the utility and improves the input power factor of the load. The control of series compensator (SERC) of the UPQC is such that it injects voltage in quadrature advance to the supply current. Thus, the SERC consumes no active power at steady state. The other advantage of the proposed control scheme is that the SERC can share the lagging VAR demand of the load with the shunt compensator (SHUC) and can ease its loading. The UPQC employing this type of quadrature voltage injection in series is termed as UPQC-Q. The VA requirement issues of SERC and SHUCs of a UPQC-Q are discussed. A PC-based new hybrid control has been proposed and the performance of the UPQC-Q is verified in a laboratory prototype. The phasor diagram, control block diagram, simulations and experimental results are presented to confirm the validity of the theory

    Clinico-Pathological Review on Pravahika vis-a-vis Amoebiasis

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    The disease Pravahika (Amoebiasis) is described after the description of Atisara (Diarrhea). Critical study of the etiopathogenesis and clinical features of Pravahika in relation to the disease amoebic dysentery as described in modern medicine reveal that the disease Pravahika includes the varied clinical syndromes of amoebic dysentery. Pravahika is a disorder of variable clinical picture. Amoebic dysentery is also of wider range with gradual onset. Pravahika may include some other dysentery also. It may not be possible to identify E. histolytica in all cases of pravahika. Similarly all cases of amoebic dysentery may not have tenesmus or Pravahana. It can be said that Pravahika is the only condition described in Ayurveda which can include amoebiasis i.e. amoebic dysentery

    Simulation of Parallel Pipeline Radix 2^2 Architecture

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    In popular orthogonal frequency division multiplexing (OFDM) communication system processing is one of the key procedures Fast Fourier transform (FFT) and inversely for that Fast Fourier Transform (IFFT) is one of them. In this VLSI implementation Structured pipeline architectures, low power consumption, high speed and reduced chip area are the important concerns. In this paper, presentation of the worthy implementation of FFT/IFFT processor for OFDM applications is described. We obtain the single-path delay feedback architecture, to get a ROM of smaller size and this proposed architecture applies a reconfigurable complex multiplier. To minimize the error of truncation we apply a fixed width modified booth multiplier. As a result, the proposed radix-2k feed forward architectures even offer an attractive solution for current applications, and also open up a new research line on feed forward structures

    Tempering of Die-steels based on indigenous materials

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    This paper present studies on the effects of quenching temperature, tempering temperature and time on the hardness of three die steels of similar carbon contents but having increasing chromium percentages. While tempering in the range of 150°C to 400°C it was observed that hardness decreased as quenching temperature was raised. All the steels showed secondary hardening phenomenon in relation to the variables mentioned above. It was also observed that on tempering the steels above 450°C, after prior quenching from increasing temperatures, hardness gradually increased upto the quenching temperature of 1100°C, beyond which followed a decrease in hardness. This phenomenon was the decrease in hardness. This phenomenon was the same at all tempering temperatures upto 601°C, but the increase in hardness from low quenching temperatures to the maximum quenching temperature was less at 450°C than at the higher temperatures and attained a maximum at 600°C secondary hardening decreased with the increase of quenching temperatur
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