Labour supply and skills demands in fashion retailing

If, as Adam Smith once famously suggested, Britain was a nation of shopkeepers then it is now a nation of shopworkers. Retail is now a significant part of the UK economy, accounting for £256 billion in sales and one-third of all consumer spending (Skillsmart, 2007). It is the largest private sector employer in the UK, employing 3m workers, or 1 in 10 of the working population. For future job creation in the UK economy retail is also similarly prominent and the sector is expected to create a further 250,000 jobs to 2014 (Skillsmart, 2007). The centrality of retail to economic success and job creation is apparent in other advanced economies. For example, within the US, retail sales is the occupation with the largest projected job growth in the period 2004-2014 (Gatta et al., 2009) and in Australia retail accounts for 1 in 6 workers (Buchanan et al., 2003). Within the UK these workers are employed in approximately 290,000 businesses, encompassing large and small organizations and also a number of sub-sectors. This variance suggests that retail should not be regarded as homogenous in its labour demands. Hart et al. (2007) note how skill requirements and the types of workers employed may differ across the sector. This chapter further opens up this point, providing an analysis of the labour supply and skills demands for the sub-sectors of clothing, footwear and leather goods, which are described by Skillsmart (2007: 48) as being 'significant categories in UK retailing'

Giving Miss Marple a makeover : graduate recruitment, systems failure and the Scottish voluntary sector

The voluntary sector in Scotland, as across the globe, is becoming increasingly business like. Resultantly, there is an increasing demand for graduates to work in business and support functions. In Scotland, however, despite an oversupply of graduates in the labor market, the voluntary sector reports skills shortages for graduate-level positions; a leadership deficit was also reported in countries such as the United States. Through exploratory, mainly qualitative, case study and stakeholder research, this article proposes that one reason for this mismatch between the supply of and demand for graduates is a systems failure within the sector. Many graduates and university students remain unaware of potentially suitable paid job opportunities, in part because of the sector's voluntary label. To rectify this systems failure, thought needs to be given to the sector's nomenclature and the manner in which voluntary sector organizations attract graduate recruits, for example, through levering value congruence in potential recruits

The Politics of Service Delivery Reform

This article identifies the leaders, the supporters and the resisters of public service reform. It adopts a principal–agent framework, comparing reality with an ‘ideal’ situation in which citizens are the principals over political policy-makers as their agents, and policy-makers are the principals over public service officials as their agents. Reform in most developing countries is complicated by an additional set of external actors — international financial institutions and donors. In practice, international agencies and core government officials usually act as the ‘principals’ in the determination of reforms. The analysis identifies the interests involved in reform, indicating how the balance between them is affected by institutional and sectoral factors. Organizational reforms, particularly in the social sectors, present greater difficulties than first generation economic policy reforms

Screening of the Proteolytic Bacteria Symbiont with Algae Gracillaria SP.

Alga laut merupakan sumberdaya alam yang melimpah di Indonesia tetapi belum optimal dimanfaatkan oleh masyarakat. Pemanfaatan rumput laut masih terbatas sebagai bahan makanan seperti Gracillaria sp. dibudidayakan sebagai bahan ekspor industri karajinan. Alga Gracillaria sp. hidupnya bersimbion dengan beraneka ragam jenis bakteri. Tujuan penelitian adalah untuk mengisolasi dan menguji aktivitas protease bakteri simbion alga Gracillaria sp. Penelitian ini berhasil mengisolasi 4 bakteri yang berbeda berdasarkan karakteristik morfologi. Keempat bekteri tersebut adalah S.G., 1 S.G., 2 S.G., 3 dan S.G., 4 Isolat bakteri S.G., 1 memiliki kemampuan menghasilkan ptotease dengan Indeks proteolitik sebesar 1,5.Kata Kunci : Bakteri simbion, Gracillaria sp. proteas

Smoothing a rugged protein folding landscape by sequence-based redesign

The rugged folding landscapes of functional proteins puts them at risk of misfolding and aggregation. Serine protease inhibitors, or serpins, are paradigms for this delicate balance between function and misfolding. Serpins exist in a metastable state that undergoes a major conformational change in order to inhibit proteases. However, conformational labiality of the native serpin fold renders them susceptible to misfolding, which underlies misfolding diseases such as $\alpha_1$-antitrypsin deficiency. To investigate how serpins balance function and folding, we used consensus design to create $\textit{conserpin}$, a synthetic serpin that folds reversibly, is functional, thermostable, and polymerization resistant. Characterization of its structure, folding and dynamics suggest that consensus design has remodeled the folding landscape to reconcile competing requirements for stability and function. This approach may offer general benefits for engineering functional proteins that have risky folding landscapes, including the removal of aggregation-prone intermediates, and modifying scaffolds for use as protein therapeutics.BTP is a Medical Research Council Career Development Fellow. AAN and JJH are supported by the Wellcome Trust (grant number WT 095195). SM acknowledges fellowship support from the Australian Research Council (FT100100960). NAB is an Australian Research Council Future Fellow (110100223). GIW is an Australian Research Council Discovery Outstanding Researcher Award Fellow (DP140100087). AMB is a National Health and Medical Research Senior Research Fellow (1022688). JCW is an NHMRC Senior Principal Research fellow and also acknowledges the support of an ARC Federation Fellowship. We thank the Australian Synchrotron for beam-time and technical assistance. This work was supported by the Multi-modal Australian ScienceS Imaging and Visualisation Environment (MASSIVE) (www.massive.org.au). We acknowledge the Monash Protein Production Unit and Monash Macromolecular Crystallization Facilit

Significance of Semantic Reconciliation in Digital Forensics

Digital forensics (DF) is a growing field that is gaining popularity among many computer professionals, law enforcement agencies and other stakeholders who must always cooperate in this profession. Unfortunately, this has created an environment replete with semantic disparities within the domain that needs to be resolved and/or eliminated. For the purpose of this study, semantic disparity refers to disagreements about the meaning, interpretation, descriptions and the intended use of the same or related data and terminologies. If semantic disparity is not detected and resolved, it may lead to misunderstandings. Even worse, since the people involved may not be from the same neighbourhood, they may not be aware of the existence of the semantic disparities, and probably might not easily realize it. The aim of this paper, therefore, is to discuss semantic disparity in DF and further elaborates on how to manage it. In addition, this paper also presents the significance of semantic reconciliation in DF. Semantic reconciliation refers to reconciling the meaning (including the interpretations and descriptions) of terminologies and data used in digital forensics. Managing semantic disparities and the significance of semantic reconciliation in digital forensics constitutes the main contributions of this paper. Keywords: Digital forensics, semantic disparity, managing semantic disparity, semantic reconciliation, significance of semantic reconciliatio

Cohort differences in disease and disability in the young-old: findings from the MRC Cognitive Function and Ageing Study (MRC-CFAS).

BACKGROUND: Projections of health and social care need are highly sensitive to assumptions about cohort trends in health and disability. We use a repeated population-based cross-sectional study from the Cambridgeshire centre of the UK Medical Research Council Cognitive Function and Ageing Study to investigate trends in the health of the young-old UK population METHODS: Non-overlapping cohorts of men and women aged 65-69 years in 1991/2 (n = 689) and 1996/7 (n = 687) were compared on: self-reported diseases and conditions; self-rated health; mobility limitation; disability by logistic regression and four-year survival by Cox Proportional Hazards Regression models, with adjustments for differences in socio-economic and lifestyle factors. RESULTS: Survival was similar between cohorts (HR: 0.91, 95% CI: 0.62 to 1.32). There was a significant increase in the number of conditions reported between cohorts, with more participants reporting 3 or more conditions in the new cohort (14.2% vs. 10.1%). When individual conditions were considered, there was a 10% increase in the reporting of arthritis and a significant increase in the reporting of chronic airways obstruction (OR: 1.36, 95% CI: 1.04 to 1.78). CONCLUSION: This study provides evidence of rising levels of ill-health, as measured by the prevalence of self-reported chronic conditions, in the newer cohorts of the young-old. Though changes in diagnosis or reporting of disease cannot, as yet, be excluded, to better understand whether our findings reflect real increases in ill-health, investment should be made into improved population-based databases, linking self-report and objective measures of health and function, and including those in long-term care

Smoothing a rugged protein folding landscape by sequence-based redesign

The rugged folding landscapes of functional proteins puts them at risk of misfolding and aggregation. Serine protease inhibitors, or serpins, are paradigms for this delicate balance between function and misfolding. Serpins exist in a metastable state that undergoes a major conformational change in order to inhibit proteases. However, conformational labiality of the native serpin fold renders them susceptible to misfolding, which underlies misfolding diseases such as α1-antitrypsin deficiency. To investigate how serpins balance function and folding, we used consensus design to create conserpin, a synthetic serpin that folds reversibly, is functional, thermostable, and polymerization resistant. Characterization of its structure, folding and dynamics suggest that consensus design has remodeled the folding landscape to reconcile competing requirements for stability and function. This approach may offer general benefits for engineering functional proteins that have risky folding landscapes, including the removal of aggregation-prone intermediates, and modifying scaffolds for use as protein therapeutics

Functional Requirements for Adding Digital Forensic Readiness as a Security Component in IoT Environments

For every contact made on a digital device, a trace is left behind; this means that every digital device contains some form of electronic evidence that may be associated to the behaviour of the users in a given environment. This evidence can be used to prove or disprove facts if a cyber-incident is detected. However, the world has seen a shift on how devices communicate and connect as a result of increased devices and connectivity, which has led to the creation of “smart environments” where the Internet of Things (IoT) plays a key role. Still, we can harness this proliferation of digital devices and smart environments to Digital Forensic (DF) technology which might help to solve the puzzle of how proactive strategies can help to minimise the time and cost needed to conduct a digital investigation. This article introduces the Functional Requirements (FRs) and processes needed when Digital Forensic Readiness (DFR) process is employed as a security component in the IoT-based environment. The paper serves as a continuation of the initially proposed architecture for adding DFR as a security component to IoT environment. The aspects and claims presented in this paper can be used as basic building blocks for implementing DFR technologies that guarantee security in the IoT-based environment. It is worth noting again that the processes that have been defined in this paper comply with the ISO/IEC 27043: 2015 International Standard

Adding Digital Forensic Readiness as a Security Component to the IoT Domain

The unique identities of remote sensing, monitoring, self-actuating, self–adapting and self-configuring “things” in Internet of Things (IoT) has come out as fundamental building blocks for the development of “smart environments”. This experience has begun to be felt across different IoT-based domains like healthcare, surveillance, energy systems, home appliances, industrial machines, smart grids and smart cities. These developments have, however, brought about a more complex and heterogeneous environment which is slowly becoming a home to cyber attackers. Digital Forensic Readiness (DFR) though can be employed as a mechanism for maximizing the potential use of digital evidence while minimizing the cost of conducting a digital forensic investigation process in IoT environments in case of an incidence. The problem addressed in this paper, therefore, is that at the time of writing this paper, there still exist no IoT architectures that have a DFR capability that is able to attain incident preparedness across IoT environments as a mechanism of preparing for post-event response process. It is on this premise, that the authors are proposing an architecture for incorporating DFR to IoT domain for proper planning and preparing in the case of security incidents. It is paramount to note that the DFR mechanism in IoT discussed in this paper complies with ISO/IEC 27043: 2015, 27030:2012 and 27017: 2015 international standards. It is the authors’ opinion that the architecture is holistic and very significant in IoT forensics