12,741 research outputs found
British economic growth and the business cycle, 1700-1870 : annual estimates
This paper provides the first annual GDP series for Great Britain over the
period 1700-1870. The series is constructed in real terms from the output side, using
volume indicators and value added weights. Sectoral estimates are provided for
agriculture, industry and services, and for a number of sub-sectors. Estimates of
nominal GDP are also provided, based on a benchmark for 1841 and projected back to
1700 and forward to 1870 using the real output series and sectoral price indices. The
new data are used to provide a consistent account of economic growth and the
business cycle. The results are broadly consistent with the long run path of real output
suggested by Crafts and Harley, although growth rates for sub-periods differ, largely
as a result of changes in the growth of agriculture. Nominal GDP increased more
rapidly than suggested by Lindert and Williamson during the eighteenth century, and
more slowly than suggested by Deane and Cole during the first half of the nineteenth
century, as a result of differences in the price indices. We also refine the business
cycle chronologies of Ashton and Gayer, Rostow and Schwartz
From Hipparcos to Gaia
The measurement of the positions, distances, motions and luminosities of
stars represents the foundations of modern astronomical knowledge. Launched at
the end of the eighties, the ESA Hipparcos satellite was the first space
mission dedicated to such measurements. Hipparcos improved position accuracies
by a factor of 100 compared to typical ground-based results and provided
astrometric and photometric multi-epoch observations of 118,000 stars over the
entire sky. The impact of Hipparcos on astrophysics has been extremely valuable
and diverse. Building on this important European success, the ESA Gaia
cornerstone mission promises an even more impressive advance. Compared to
Hipparcos, it will bring a gain of a factor 50 to 100 in position accuracy and
of a factor of 10,000 in star number, collecting photometric,
spectrophotometric and spectroscopic data for one billion celestial objects.
During its 5-year flight, Gaia will measure objects repeatedly, up to a few
hundred times, providing an unprecedented database to study the variability of
all types of celestial objects. Gaia will bring outstanding contributions,
directly or indirectly, to most fields of research in astrophysics, such as the
study of our Galaxy and of its stellar constituents, the search for planets
outside the solar system.Comment: 6 pages. New Horizons in Time Domain Astronomy Proceedings IAU
Symposium No. 285, 2012, E. Griffin, B. Hanisch & R. Seaman, ed
Learning what matters - Sampling interesting patterns
In the field of exploratory data mining, local structure in data can be
described by patterns and discovered by mining algorithms. Although many
solutions have been proposed to address the redundancy problems in pattern
mining, most of them either provide succinct pattern sets or take the interests
of the user into account-but not both. Consequently, the analyst has to invest
substantial effort in identifying those patterns that are relevant to her
specific interests and goals. To address this problem, we propose a novel
approach that combines pattern sampling with interactive data mining. In
particular, we introduce the LetSIP algorithm, which builds upon recent
advances in 1) weighted sampling in SAT and 2) learning to rank in interactive
pattern mining. Specifically, it exploits user feedback to directly learn the
parameters of the sampling distribution that represents the user's interests.
We compare the performance of the proposed algorithm to the state-of-the-art in
interactive pattern mining by emulating the interests of a user. The resulting
system allows efficient and interleaved learning and sampling, thus
user-specific anytime data exploration. Finally, LetSIP demonstrates favourable
trade-offs concerning both quality-diversity and exploitation-exploration when
compared to existing methods.Comment: PAKDD 2017, extended versio
Contribution of postnatal collagen reorientation to depth-dependent mechanical properties of articular cartilage
The collagen fibril network is an important factor for the depth-dependent mechanical behaviour of adult articular cartilage (AC). Recent studies show that collagen orientation is parallel to the articular surface throughout the tissue depth in perinatal animals, and that the collagen orientations transform to a depth-dependent arcade-like structure in adult animals. Current understanding on the mechanobiology of postnatal AC development is incomplete. In the current paper, we investigate the contribution of collagen fibril orientation changes to the depth-dependent mechanical properties of AC. We use a composition-based finite element model to simulate in a 1-D confined compression geometry the effects of ten different collagen orientation patterns that were measured in developing sheep. In initial postnatal life, AC is mostly subject to growth and we observe only small changes in depth-dependent mechanical behaviour. Functional adaptation of depth-dependent mechanical behaviour of AC takes place in the second half of life before puberty. Changes in fibril orientation alone increase cartilage stiffness during development through the modulation of swelling strains and osmotic pressures. Changes in stiffness are most pronounced for small stresses and for cartilage adjacent to the bone. We hypothesize that postnatal changes in collagen fibril orientation induce mechanical effects that in turn promote these changes. We further hypothesize that a part of the depth-dependent postnatal increase in collagen content in literature is initiated by the depth-dependent postnatal increase in fibril strain due to collagen fibril reorientatio
Does individual variation in metabolic phenotype predict fish behaviour and performance?
There is increasing interest in documenting and explaining the existence of marked intraspecific variation in metabolic rate in animals, with fishes providing some of the best-studied examples. After accounting for variation due to other factors, there can typically be a two to three-fold variation among individual fishes for both standard and maximum metabolic rate (SMR and MMR). This variation is reasonably consistent over time (provided that conditions remain stable), and its underlying causes may be influenced by both genes and developmental conditions. In this paper, current knowledge of the extent and causes of individual variation in SMR, MMR and aerobic scope (AS), collectively its metabolic phenotype, is reviewed and potential links among metabolism, behaviour and performance are described. Intraspecific variation in metabolism has been found to be related to other traits: fishes with a relatively high SMR tend to be more dominant and grow faster in high food environments, but may lose their advantage and are more prone to risk-taking when conditions deteriorate. In contrast to the wide body of research examining links between SMR and behavioural traits, very little work has been directed towards understanding the ecological consequences of individual variation in MMR and AS. Although AS can differ among populations of the same species in response to performance demands, virtually nothing is known about the effects of AS on individual behaviours such as those associated with foraging or predator avoidance. Further, while factors such as food availability, temperature, hypoxia and the fish's social environment are known to alter resting and MMRs in fishes, there is a paucity of studies examining how these effects vary among individuals, and how this variation relates to behaviour. Given the observed links between metabolism and measures of performance, understanding the metabolic responses of individuals to changing environments will be a key area for future research because the environment will have a strong influence on which animals survive predation, become dominant and ultimately have the highest reproductive success. Although current evidence suggests that variation in SMR may be maintained within populations via context-dependent fitness benefits, it is suggested that a more integrative approach is now required to fully understand how the environment can modulate individual performance via effects on metabolic phenotypes encompassing SMR, MMR and AS
Strongly coupled modes in a weakly driven micromechanical resonator
We demonstrate strong coupling between the flexural vibration modes of a
clamped-clamped micromechanical resonator vibrating at low amplitudes. This
coupling enables the direct measurement of the frequency response via
amplitude- and phase modulation schemes using the fundamental mode as a
mechanical detector. In the linear regime, a frequency shift of
is observed for a mode with a line width of
in vacuum. The measured response is well-described by the
analytical model based on the Euler-Bernoulli beam including tension.
Calculations predict an upper limit for the room-temperature Q-factor of
for our top-down fabricated micromechanical beam
resonators.Comment: 9 pages, 2 figure
Some modifications to the SNIP journal impact indicator
The SNIP (source normalized impact per paper) indicator is an indicator of
the citation impact of scientific journals. The indicator, introduced by Henk
Moed in 2010, is included in Elsevier's Scopus database. The SNIP indicator
uses a source normalized approach to correct for differences in citation
practices between scientific fields. The strength of this approach is that it
does not require a field classification system in which the boundaries of
fields are explicitly defined. In this paper, a number of modifications that
will be made to the SNIP indicator are explained, and the advantages of the
resulting revised SNIP indicator are pointed out. It is argued that the
original SNIP indicator has some counterintuitive properties, and it is shown
mathematically that the revised SNIP indicator does not have these properties.
Empirically, the differences between the original SNIP indicator and the
revised one turn out to be relatively small, although some systematic
differences can be observed. Relations with other source normalized indicators
proposed in the literature are discussed as well
Challenges and Pitfalls in Human Milk Oligosaccharide Analysis
Human milk oligosaccharides have been recognized as an important, functional biomolecule in mothers' milk. Moreover, these oligosaccharides have been recognized as the third most abundant component of human milk, ranging from 10-15 g/L in mature milk and up to and over 20 g/L reported in colostrum. Initially, health benefits of human milk oligosaccharides were assigned via observational studies on the differences between breastfed and bottle fed infants. Later, pools of milk oligosaccharides were isolated and used in functional studies and in recent years more specific studies into structure-function relationships have identified some advanced roles for milk oligosaccharides in the healthy development of infants. In other research, the levels, diversity, and complexity of human milk oligosaccharides have been studied, showing a wide variation in results. This review gives a critical overview of challenges in the analysis of human milk oligosaccharides. In view of the myriad functions that can be assigned, often to specific structures or classes of structures, it is very relevant to assess the levels of these structures in the human milk correctly, as well as in other biological sample materials. Ultimately, the review makes a case for a comparative, inter-laboratory study on quantitative human milk oligosaccharide analysis in all relevant biological samples
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