44 research outputs found
Correcting the quantum clock: conditional sojourn times
Can the quantum-mechanical sojourn time be clocked without the clock
affecting the sojourn time? Here we re-examine the previously proposed
non-unitary clock, involving absorption/amplification by an added infinitesimal
imaginary potential(), and find it {\it not} to preserve, in general,
the positivity of the sojourn time, conditional on eventual reflection or
transmission. The sojourn time is found to be affected by the scattering
concomitant with the mismatch, however small, due to the very clock
potential() introduced for the purpose, as also by any prompt
scattering involving partial waves that have not traversed the region of
interest. We propose a formal procedure whereby the sojourn time so clocked can
be corrected for these spurious scattering effects. The resulting conditional
sojourn times are then positive definite for an arbitrary potential, and have
the proper high- and low-energy limits.Comment: Corrected and rewritten, RevTeX, 4 pages, 2 figures (ps files)
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Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes
Online Correction for: https://doi.org/10.1038/s41586-020-2493-4 | Erratum for https://bura.brunel.ac.uk/handle/2438/21299In the version of this article initially published, two members of the ENCODE Project Consortium were missing from the author list. Rizi Ai (Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, USA) and Shantao Li (Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA) are now included in the author list. These errors have been corrected in the online version of the article : 'Expanded encyclopaedias of DNA elements in the human and mouse genomes'.https://www.nature.com/articles/s41586-021-04226-3https://www.nature.com/articles/s41586-021-04226-
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Perspectives on ENCODE
Supplementary information is available for this paper at https://doi.org/10.1038/s41586-020- 2449-8.© 2020, The Author(s). The Encylopedia of DNA Elements (ENCODE) Project launched in 2003 with the long-term goal of developing a comprehensive map of functional elements in the human genome. These included genes, biochemical regions associated with gene regulation (for example, transcription factor binding sites, open chromatin, and histone marks) and transcript isoforms. The marks serve as sites for candidate cis-regulatory elements (cCREs) that may serve functional roles in regulating gene expression1. The project has been extended to model organisms, particularly the mouse. In the third phase of ENCODE, nearly a million and more than 300,000 cCRE annotations have been generated for human and mouse, respectively, and these have provided a valuable resource for the scientific community.NIH grants: U01HG007019, U01HG007033, U01HG007036, U01HG007037, U41HG006992, U41HG006993, U41HG006994, U41HG006995, U41HG006996, U41HG006997, U41HG006998, U41HG006999, U41HG007000, U41HG007001, U41HG007002, U41HG007003, U41HG007234, U54HG006991, U54HG006997, U54HG006998, U54HG007004, U54HG007005, U54HG007010 and UM1HG009442
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This report presents data gathered by the Naval Postgraduate School (NPS) during the South Central Coast Aerometric Monitoring Project (SCCCAMP) in September and October of 1985. The data are from a triaxial monostatic doppler acoustic sounder and a 20-meter meteorological tower which were located at the Ellwood pier near Goleta, California and from rawinsondes launched from the R/V Acania in the Santa Barbara Channel. Keywords include: Boundary layer, Doppler Acoustic Sounder, and Rawinsondehttp://archive.org/details/sodarrawinsondes00shawN
A review of the methodological aspects of aminoacid racemisation for use in forensic sciences
Accurate age determination of adult cadavers and human remains is a key requirement in
forensic practice. The current morphological methods lack accuracy and precision, require
specialist training and are costly. The use of aspartic acid racemization (AAR) in human dentine
provides a simple, cost-effective solution and the method can achieve accuracies of 63 years at
best. Currently, there are differences in AAR methodology between laboratories which produce
different results on the rate of racemization in teeth. These inconsistencies must be resolved if the
technique is to be successfully applied to age determinations in forensic cases. This paper reviews
the differences in protocol which have been used, discusses how each method will affect the
results obtained from AAR analysis and gives recommendations for optimization of the
methological protocol as a \ufb01rst step towards international standardization
Age estimation : the state of the art in relation to the specific demands of forensic practise
Age estimation in cadavers, human remains and living individuals may clarify issues with significant legal and social ramifications for individuals as well as for the community. In such cases methods for estimating age should fulfil the following specific demands: (1) they must have been presented to the scientific community, as a rule by publication in peer-reviewed journals, (2) clear information concerning accuracy of age estimation by the method should be available, (3) the methods need to be sufficiently accurate and (4) in cases of age estimation in living individuals principles of medical ethics and legal regulations have to be considered. We have identified and summarized the methods that essentially fulfil these specific demands. In childhood and adolescence morphological methods based on the radiological examination of dental and skeletal development are to be recommended. In adulthood, the accuracy of most morphological methods is much reduced. Here a biochemical method based on aspartic acid racemization in dentine provides the most accurate estimates of age, followed by special morphological dental and skeletal methods. The choice of method has to take account of the individual circumstances of each case. Most methods require either the consultation of specialised and trained scientists or an adequate calibration by the \u201cuser\u201d. Very few attempts have been made to find common standardisation, calibration and evaluation procedures or to develop means of quality assurance for methods of age estimation. Efforts in these directions are necessary to guarantee quality standards and adequate answers to the important legal and social issue of age estimation in forensic medicine