EducaFarma 11.0

Memoria ID2022-036. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2022-2023

EducaFarma 9.0

Memoria ID-020 Ayudas de la Universidad de Salamanca para la innovación docente, curso 2020-2021

Educafarma 10.0

Memoria ID-030. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2021-2022

Estudio comparativo de contrastes hidrosolubles iónicos y no iónicos para el examen de la urografía excretora en la especie canina / Eugenio Hita Rosino ; [bajo la dirección de Miguel Angel Sánchez-Valverde García y Amalia Agut Giménez].

Tesis-Universidad de Murcia.Consulte la tesis en: BCA. GENERAL. ARCHIVO UNIVERSITARIO. T.M.-1624.Consulte la tesis en: BCA. GENERAL. Fac. Veterinaria. Sala de estudio. Tesis-V 99

Wettability and osteoblastic cell adhesion on ultrapolished commercially pure titanium surfaces: the role of the oxidation and pollution states

The oxidation state of the surfaces of titanium-based biomaterials strongly depends on their previous history. This factor affects the titanium wettability and it probably conditions the success of the implanted biomaterials. However, the separate role of the pollution and oxidation states of metallic titanium surfaces remains still controversial. To elucidate this, it is required to standardize the initial surface state of titanium in terms of roughness and surface chemistry and then, to monitor its wettability after the corresponding treatment. In this work, we studied finely polished surfaces of commercially pure titanium (cpTi) which were subjected to cleaning surface treatments. XPS was used to characterize the surface chemistry and the oxide film thickness. The contact angle hysteresis in underwater conditions was measured with the growing/shrinking captive bubble method, which allowed for mimicking the real conditions of implantable devices. The water wettability of smooth cpTi surfaces was stabilized with weak thermal oxidation (230ºC, 30 min). The osteoblastic cell response of the stabilized and non-stabilized cpTi surfaces was analyzed. Although the oxidation and pollution states were also stabilized and normalized, no correlation was observed between the stable response in wettability of titanium and its cell adhesion.This study was supported by the “Ministry of Science and Innovation”' (project MAT2011-23339) and by the “Junta de Andalucia” (projects P09-FQM-4698 and P10-FQM-5977)