Data collection system: Earth Resources Technology Satellite-1

Subjects covered at the meeting concerned results on the overall data collection system including sensors, interface hardware, power supplies, environmental enclosures, data transmission, processing and distribution, maintenance and integration in resources management systems

The use of lasers for hydrographic studies

The utilization of remote laser sensors in water pollution detection and identification, coastal environmental monitoring, and bathymetric depth sounding, is discussed. q

Realization of an all-optical zero to π cross-phase modulation jump

We report on the experimental demonstration of an all-optical π cross-phase modulation jump. By performing a preselection, an optically induced unitary transformation, and then a postselection on the polarization degree of freedom, the phase of the output beam acquires either a zero or π phase shift (with no other possible values). The postselection results in optical loss in the output beam. An input state may be chosen near the resulting phase singularity, yielding a pi phase shift even for weak interaction strengths. The scheme is experimentally demonstrated using a coherently prepared dark state in a warm atomic cesium vapor

Intravital Multiphoton Microscopy with Fluorescent Bile Salts in Rats as an In Vivo Biomarker for Hepatobiliary Transport Inhibition

The bile salt export pump (BSEP) is expressed at the canalicular domain of hepatocytes, where it mediates the elimination of monovalent bile salts into the bile. Inhibition of BSEP is considered a susceptibility factor for drug-induced liver injury that often goes undetected during nonclinical testing. Although in vitro assays exist for screening BSEP inhibition, a reliable and specific method for confirming Bsep inhibition in vivo would be a valuable follow up to a BSEP screening strategy, helping to put a translatable context around in vitro inhibition data, incorporating processes such as metabolism, protein binding, and other exposure properties that are lacking in most in vitro BSEP models. Here, we describe studies in which methods of quantitative intravital microscopy were used to identify dose-dependent effects of two known BSEP/Bsep inhibitors, 2-[4-[4-(butylcarbamoyl)-2-[(2,4-dichlorophenyl)sulfonylamino]phenoxy]-3-methoxyphenyl]acetic acid (AMG-009) and bosentan, on hepatocellular transport of the fluorescent bile salts cholylglycyl amidofluorescein and cholyl-lysyl-fluorescein in rats. Results of these studies demonstrate that the intravital microscopy approach is capable of detecting Bsep inhibition at drug doses well below those found to increase serum bile acid levels, and also indicate that basolateral efflux transporters play a significant role in preventing cytosolic accumulation of bile acids under conditions of Bsep inhibition in rats. Studies of this kind can both improve our understanding of exposures needed to inhibit Bsep in vivo and provide unique insights into drug effects in ways that can improve our ability interpret animal studies for the prediction of human drug hepatotoxicity

Bullous hemorrhagic lichen sclerosus of the breast: a report of two cases and review of the literature

Lichen sclerosus (LS) is a chronic dermatologic condition characterized by atrophic porcelain-appearing plaques that can cause intense discomfort and eventually lead to destruction of local architecture. Lichen sclerosus most commonly arises in the anogenital area, but up to 20% of cases can present on extragenital skin. Rarely, LS can also present with hemorrhage and bullae; the mechanism by which this occurs is unknown. We report two cases of bullous hemorrhagic LS of the breast arising in 66-year-old and 77-year-old women. Bullous hemorrhagic LS of the breast is exceedingly rare, with few reported cases, and presents a diagnostic challenge to clinicians

Extending Sibgatullin's ansatz for the Ernst potential to generate a richer family of axially symmetric solutions of Einstein's equations

The scope of this talk is to present some preliminary results on an effort, currently in progress, to generate an exact solution of Einstein's equation, suitable for describing spacetime around a rotating compact object. Specifically, the form of the Ernst potential on the symmetry axis and its connection with the multipole moments is discussed thoroughly. The way to calculate the multipole moments of spacetime directly from the value of the Ernst potential on the symmetry axis is presented. Finally, a mixed ansatz is formed for the Ernst potential including parameters additional to the ones dictated by Sibgatullin. Thus, we believe that this talk can also serve as a comment on choosing the appropriate ansatz for the Ernst potential.Comment: Talk given in the 11th Conference on Recent Developments in Gravity, 2-5 June 2004, Lesbos, Greec

Rights through alliances; findings from a European project tackling homophobic and transphobic bullying in schools through the engagement of families and young people

This paper draws on key findings from a European project ‘Rights through alliances: Innovating and networking both within homes and schools’ (RAINBOW-HAS) conducted between 2013 and 2015. RAINBOW-HAS was co-funded by the Fundamental Rights and Citizenship programme of the EU and aimed to build collaboration between six European Union countries; Bulgaria, Belgium, Italy, Poland, Spain and the UK to analyse and improve the rights of children and youth vis-à-vis affective sexual diversity regarding sexual orientation and gender identity in educational settings. It looked at how participating countries builds bridges and alliances between and across Europe by sharing aspects of good practice through an evidence base and drawing on the strengths generated through learning and dialogue in the context of different contexts, legislation and policies, institution, cultures as well as socio-economic and political differences. RAINBOW-HAS brought important concepts from Europe into the individual domestic contexts through its direct engagement with young people and their families within selected local contexts. LGB parents in particular discuss their children’s experiences of bullying. They were found to be discursively and rhetorically designed to deal with a heteronormative and gender neutral social/political context. We explore whether reports of bullying are equally if not more risky for LGB parents, given the ongoing challenges and undermining of LGB parenting and ask critical questions about bullying by placing it in a broader political and cultural context. Thematic analysis of the qualitative interviews undertaken with a range of different families, schools and community associations (n=174) provided a snapshot of contemporary practice across the European context. Through this approach, we identified discourses used to address discrimination and the implications for developing a more in-depth dialogue with stakeholders. This has implications for promoting family and young people’s own engagement and in challenging homophobic and transphobic bullying and the need to question the relative silence of social work in addressing this. European Union Agency for Fundamental Rights (2013) EU LGBT Survey: European Union lesbian, gay, bisexual and transgender survey: Results at a Glance. Luxembourg: Publications Office of the European Union

Biblio-sitography of the UK context rights through alliances: innovating and networking both within homes and schools

This background context paper provides an overview and highlights from the UK in relation to homophobic bullying in schools. The paper was prepared for Workstream 1 of the Rainbow Has European Funded Project involving 6 European countries and which looked at the Rights Through Alliances: Innovating and Networking Both Within Homes And Schools between 2012-15. This paper describes the UK context and other participating countries prepared a similar background paper to inform a comparative approach and to benchmark activity across Europe. The full project report and other outputs from the programme can be viewed on the project website http://rainbowhas.eu