Perceptions of Library Gamers at the Public Library of Charlotte and Mecklenburg County's Teen Loft

Some libraries are using video games to get young adults interested and active at their local public libraries. When exploring gamers and the use of video games in libraries, it is important to put the topic in context of what young adults want from the library and what types of programs, especially those focusing on video games, are successful in getting teens to patronize the library. This study examines the views of young adult library gamers on the idea of playing video games in the library and on public libraries in general. Participants of the Gaming Club at the Public Library of Charlotte and Mecklenburg County's Teen Loft were interviewed to look at their thoughts and perceptions of libraries and playing video games at the library

Motion transduction with thermo-mechanically squeezed graphene resonator modes

There is a recent surge of interest in amplification and detection of tiny motion in the growing field of opto- and electromechanics. Here, we demonstrate widely tunable, broad bandwidth, and high gain all-mechanical motion amplifiers based on graphene/silicon nitride (SiNx) hybrids. In these devices, a tiny motion of a large-area SiNx membrane is transduced to a much larger motion in a graphene drum resonator coupled to SiNx. Furthermore, the thermal noise of graphene is reduced (squeezed) through parametric tension modulation. The parameters of the amplifier are measured by photothermally actuating SiNx and interferometrically detecting graphene displacement. We obtain a displacement power gain of 38 dB and demonstrate 4.7 dB of squeezing, resulting in a detection sensitivity of 3.8 [...], close to the thermal noise limit of SiNx

A blowup criterion for ideal viscoelastic flow

We establish an analog of the Beale-Kato-Majda criterion for singularities of smooth solutions of the system of PDE arising in the Oldroyd model for ideal viscoelastic flow

Trypanosoma teixeirae: A new species belonging to the T. cruzi clade causing trypanosomosis in an Australian little red flying fox (Pteropus scapulatus)

Little is known about the genetic diversity and pathogenicity of trypanosomes in Australian bats. Recently a novel trypanosome species was identified in an adult female little red flying fox (Pteropus scapulatus) with clinical and pathological evidence of trypanosomosis. The present study used morphology and molecular methods to demonstrate that this trypanosome is a distinct species and we propose the name Trypanosoma teixeirae sp. n. Morphological comparison showed that its circulating trypomastigotes were significantly different from those of Trypanosoma pteropi and Trypanosoma hipposideri, two species previously described from Australian bats. Genetic information was not available for T. pteropi and T. hipposideri but phylogenetic analyses at the 18S ribosomal RNA (rRNA) and glycosomal glyceraldehyde phosphate dehydrogenase (gGAPDH) loci indicated that T. teixeirae sp. n. was genetically distinct and clustered with other bat-derived trypanosome species within the Trypanosoma cruzi clade

Trypanosomiasis in an Australian little red flying fox (Pteropus scapulatus)

Case report An adult female Australian little red flying fox (Pteropus scapulatus) presented with icterus and anaemia. Examination of a blood smear revealed numerous trypanosomes 20.4-30.8 mu m long with tapered ends. Necropsy and histological findings were consistent with trypanosome infection of lymphoid tissue and intravascular haemolysis. Sequence and phylogenetic analysis demonstrated this trypanosome species to be genetically distinct and most similar to Trypanosoma minasense and Trypanosoma rangeli (with a genetic distance of 1% at the 18S rRNA locus for both). Conclusion To the authors' knowledge this is the first report of a trypanosome infection associated with clinical disease in bats

The Applications and Challenges of the Development of In Vitro Tumor Microenvironment Chips

The tumor microenvironment (TME) plays a critical, yet mechanistically elusive role in tumor development and progression, as well as drug resistance. To better understand the pathophysiology of the complex TME, a reductionist approach has been employed to create in vitro microfluidic models called “tumor chips”. Herein, we review the fabrication processes, applications, and limitations of the tumor chips currently under development for use in cancer research. Tumor chips afford capabilities for real-time observation, precise control of microenvironment factors (e.g. stromal and cellular components), and application of physiologically relevant fluid shear stresses and perturbations. Applications for tumor chips include drug screening and toxicity testing, assessment of drug delivery modalities, and studies of transport and interactions of immune cells and circulating tumor cells with primary tumor sites. The utility of tumor chips is currently limited by the ability to recapitulate the nuances of tumor physiology, including extracellular matrix composition and stiffness, heterogeneity of cellular components, hypoxic gradients, and inclusion of blood cells and the coagulome in the blood microenvironment. Overcoming these challenges and improving the physiological relevance of in vitro tumor models could provide powerful testing platforms in cancer research and decrease the need for animal and clinical studies

Comparing Formulations of Generalized Quantum Mechanics for Reparametrization-Invariant Systems

A class of decoherence schemes is described for implementing the principles of generalized quantum theory in reparametrization-invariant `hyperbolic' models such as minisuperspace quantum cosmology. The connection with sum-over-histories constructions is exhibited and the physical equivalence or inequivalence of different such schemes is analyzed. The discussion focuses on comparing constructions based on the Klein-Gordon product with those based on the induced (a.k.a. Rieffel, Refined Algebraic, Group Averaging, or Spectral Analysis) inner product. It is shown that the Klein-Gordon and induced products can be simply related for the models of interest. This fact is then used to establish isomorphisms between certain decoherence schemes based on these products.Comment: 21 pages ReVTe

Using stable-hydrogen isotopes to reveal immigration in an Arctic-breeding songbird population

Background: Knowledge of immigration and emigration rates is crucial for understanding of population dynamics, yet little is known about these vital rates, especially for arctic songbirds. We estimated immigration in an Arctic population of northern wheatears on Baffin Island, Canada, by the use of stable hydrogen isotopes in tail feathers (d2HK). We assumed that d2HK values of juvenile (hatch-year) feathers grown at the breeding grounds were representative of the local population, while those of breeding adults were indicative of where they grew their feathers during their postbreeding molt the previous year. The extent to which adul

On Higher Order Gravities, Their Analogy to GR, and Dimensional Dependent Version of Duff's Trace Anomaly Relation

An almost brief, though lengthy, review introduction about the long history of higher order gravities and their applications, as employed in the literature, is provided. We review the analogous procedure between higher order gravities and GR, as described in our previous works, in order to highlight its important achievements. Amongst which are presentation of an easy classification of higher order Lagrangians and its employment as a \emph{criteria} in order to distinguish correct metric theories of gravity. For example, it does not permit the inclusion of only one of the second order Lagrangians in \emph{isolation}. But, it does allow the inclusion of the cosmological term. We also discuss on the compatibility of our procedure and the Mach idea. We derive a dimensional dependent version of Duff's trace anomaly relation, which in \emph{four}-dimension is the same as the usual Duff relation. The Lanczos Lagrangian satisfies this new constraint in \emph{any} dimension. The square of the Weyl tensor identically satisfies it independent of dimension, however, this Lagrangian satisfies the previous relation only in three and four dimensions.Comment: 30 pages, added reference

Field Measurements of Terrestrial and Martian Dust Devils

Surface-based measurements of terrestrial and martian dust devils/convective vortices provided from mobile and stationary platforms are discussed. Imaging of terrestrial dust devils has quantified their rotational and vertical wind speeds, translation speeds, dimensions, dust load, and frequency of occurrence. Imaging of martian dust devils has provided translation speeds and constraints on dimensions, but only limited constraints on vertical motion within a vortex. The longer mission durations on Mars afforded by long operating robotic landers and rovers have provided statistical quantification of vortex occurrence (time-of-sol, and recently seasonal) that has until recently not been a primary outcome of more temporally limited terrestrial dust devil measurement campaigns. Terrestrial measurement campaigns have included a more extensive range of measured vortex parameters (pressure, wind, morphology, etc.) than have martian opportunities, with electric field and direct measure of dust abundance not yet obtained on Mars. No martian robotic mission has yet provided contemporaneous high frequency wind and pressure measurements. Comparison of measured terrestrial and martian dust devil characteristics suggests that martian dust devils are larger and possess faster maximum rotational wind speeds, that the absolute magnitude of the pressure deficit within a terrestrial dust devil is an order of magnitude greater than a martian dust devil, and that the time-of-day variation in vortex frequency is similar. Recent terrestrial investigations have demonstrated the presence of diagnostic dust devil signals within seismic and infrasound measurements; an upcoming Mars robotic mission will obtain similar measurement types