The International Space Station: A Low-Earth Orbit (LEO) Test Bed for Advancements in Space and Environmental Medicine

Ground-based space analog projects such as the NASA Extreme Environment Mission Operations (NEEMO) can be valuable test beds for evaluation of experimental design and hardware feasibility before actually being implemented on orbit. The International Space Station (ISS) is an closed-system laboratory that orbits 240 miles above the Earth, and is the ultimate extreme environment. Its inhabitants spend hours performing research that spans from fluid physics to human physiology, yielding results that have implications for Earth-based improvements in medicine and health, as well as those that will help facilitate the mitigation of risks to the human body associated with exploration-class space missions. ISS health and medical experiments focus on pre-flight and in-flight prevention, in-flight treatment, and postflight recovery of health problems associated with space flight. Such experiments include those on enhanced medical monitoring, bone and muscle loss prevention, cardiovascular health, immunology, radiation and behavior. Lessons learned from ISS experiments may not only be applicable to other extreme environments that face similar capability limitations, but also serve to enhance standards of care for everyday use on Earth

Gravity-independent constant force resistive exercise unit

This invention describes a novel gravity-independent exercise unit designed for use in microgravity, or on the ground, as a means by which to counter muscle atrophy and bone degradation due to disuse or underuse. Modular resistive packs comprising constant torque springs provide constant force opposing the withdrawal of an exercise cable from the device. In addition to uses within the space program, the compact resistive packs of the CFREU allow the unit to be small enough for easy use as a home gym for personal use, or as a supplement for rehabilitation programs. Resistive packs may be changed conveniently out of the CFREU according to the desired exercise regimen. Thus, the resistive packs replace the need for expensive, heavy, and bulky traditional weight plates. The CFREU may be employed by hospitals, rehabilitation and physical therapy clinics, and other related professional businesses

Impact of the International Space Station Research Results

The International Space Station (ISS) facilitates research that benefits human lives on Earth and serves as the primary testing ground for technology development to sustain life in the extreme environment of space. To date, investigators have published a wide range of ISS science results, from improved theories about the creation of stars to the outcome of data mining omics repositories of previously completed ISS investigations. Because of the unique microgravity environment of the ISS laboratory and the multidisciplinary and international nature of the research, analyzing ISS scientific impacts is an exceptional challenge. As a result, the ISS Program Science Forum (PSF), made up of senior science representatives across the ISS international partnership, uses various methods to describe the impacts of ISS research activities. For the most part, past papers written by PSF members to assess the overall ISS research impact have focused on exhibiting ISS research impact by quantifying ISS research output or its perceived benefits for humanity. This paper proposes a new assessment of ISS impact from the perspective of the end users needs. To that end, the authors use visualizations and metrics of scientific publication data to show the ISS research influence on traditional scientific fields, its global reach and the benefits to people across the globe

Updated Benefits for Humanity, Third Edition (B4H3), from the International Space Station (ISS)

In 2018, the International Space Station (ISS) [Figure 1] partnership completed a revision for the third edition of the International Space Station Benefits for Humanity, a compilation of case studies of benefits being realized from ISS activities in the areas of human health, Earth observations and disaster response, innovative technology, global education, and economic development of space. The revision included new assessments of economic value and scientific value with more detail than the second edition. The third edition contains updated statistics on the impacts of the benefits as well as new benefits that have developed since the previous publication. This presentation will summarize the updates on behalf of the ISS Program Science Forum, which consists of senior science representatives across the ISS international partnership. An independent consultant determined the economic valuation (EV) of ISS research benefits case studies and the third edition contains the results. The process involved a preliminary assessment of economic, social, and innovation factors. A more detailed assessment followed, which included factors such as addressable market, market penetration, revenue generation, ability to leverage across other applications or customer groups, quality of life improvements, health benefits, environmental benefits, cultural and community cohesion, inspiration, new knowledge, novel approaches, creation of a unique market niche, and research leadership. Because of the unique microgravity environment of the ISS laboratory, the multidisciplinary and international nature of the research, and the significance of the investment in its development, analyzing ISS scientific impacts is an exceptional challenge. As a result, the ISS partnership determined the scientific valuation (SV) of ISS research using a combination of citation analyses, bibliometrics, and narratives of important ISS utilization results. Approximately 2,100 ISS results publications comprised of scientific journal articles, conference proceedings, and gray literature, representing over 5,000 authors and co-authors on Earth were used in this evaluation to enable the communication of impacts of ISS research on various science and technology fields across many countries. The publication also updates and expands the previously described benefits of research results in the areas of space commerce, technology development, human health, environmental change and disaster response, and education activities. Distinct benefits return to Earth from the only orbiting multidisciplinary laboratory of its kind. The ISS is a stepping-stone for future space exploration while also providing findings that develop low Earth orbit as a place for sustained human activity and improve life on our planet

Impact of the International Space Station Research Results

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International Space Station Research and Facilities for Life Sciences

Assembly of the International Space Station is nearing completion in fall of 2010. Although assembly has been the primary objective of its first 11 years of operation, early science returns from the ISS have been growing at a steady pace. Laboratory facilities outfitting has increased dramatically 2008-2009 with the European Space Agency s Columbus and Japanese Aerospace Exploration Agency s Kibo scientific laboratories joining NASA s Destiny laboratory in orbit. In May 2009, the ISS Program met a major milestone with an increase in crew size from 3 to 6 crewmembers, thus greatly increasing the time available to perform on-orbit research. NASA will launch its remaining research facilities to occupy all 3 laboratories in fall 2009 and winter 2010. To date, early utilization of the US Operating Segment of the ISS has fielded nearly 200 experiments for hundreds of ground-based investigators supporting international and US partner research. With a specific focus on life sciences research, this paper will summarize the science accomplishments from early research aboard the ISS- both applied human research for exploration, and research on the effects of microgravity on life. We will also look ahead to the full capabilities for life sciences research when assembly of ISS is complete in 2010