12 research outputs found
The structure of model membranes studied by vibrational sum frequency spectroscopy
The structure and order of insoluble Langmuir monolayers consisting of 1,2-distearoyl-sn-glycero-3-phosphatidylcholine (DSPC or 18:0 PC) and the surrounding water molecules have been investigated by vibrational sum frequency spectroscopy (VSFS). At surface pressures of 1, 15, and 57 mN/m corresponding to molecular areas of 53, 50, and 43 Ă
2, respectively, the DSPC molecules formed a well ordered film. Both the VSF signal from the methyl stretching vibrations of the lipid and the surrounding water increased with enhanced surface pressure, as a result of the higher surface density and increased order of the system. Water molecules hydrating the polar parts of the headgroup and in close contact to the hydrocarbon groups of the lipid were observed in all three polarization combinations of the laser beams, and distinguished by their different vibrational frequencies.Jonathan F. D. Liljeblad, Mark W. Rutland, Vincent Bulone, C. Magnus Johnso
Can Cobalt(II) and Chromium(III) Ions Released from Joint Prostheses Influence the Friction Coefficient?
Cobalt
chromium molybdenum alloys (CoCrMo) are commonly used as
articulating components in joint prostheses. In this tribocorrosive
environment, wear debris and metal ionic species are released and
interact with proteins, possibly resulting in protein aggregation.
This study aimed to investigate whether this could have an effect
on the friction coefficient in a typical material couple, namely CoCrMo-on-polyethylene.
It was confirmed that both CoÂ(II) and CrÂ(III) ions, and their combination,
at concentrations relevant for the metal release situation, resulted
in protein aggregation and its concomitant precipitation, which increased
the friction coefficient. Future studies should identify the clinical
importance of these findings