53 research outputs found
Novel compound mutations in the mitochondrial translation elongation factor (TSFM) gene cause severe cardiomyopathy with myocardial fibro-adipose replacement
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2019
- Field of study
Primary mitochondrial dysfunction is an under-appreciated cause of cardiomyopathy, especially when cardiac symptoms are the unique or prevalent manifestation of disease. Here, we report an unusual presentation of mitochondrial cardiomyopathy, with dilated phenotype and pathologic evidence of biventricular fibro-adipose replacement, in a 33-year old woman who underwent cardiac transplant. Whole exome sequencing revealed two novel compound heterozygous variants in the TSFM gene, coding for the mitochondrial translation elongation factor EF-Ts. This protein participates in the elongation step of mitochondrial translation by binding and stabilizing the translation elongation factor Tu (EF-Tu). Bioinformatics analysis predicted a destabilization of the EF-Ts variants complex with EF-Tu, in agreement with the dramatic steady-state level reduction of both proteins in the clinically affected myocardium, which demonstrated a combined respiratory chain enzyme deficiency. In patient fibroblasts, the decrease of EF-Ts was paralleled by up-regulation of EF-Tu and induction of genes involved in mitochondrial biogenesis, along with increased expression of respiratory chain subunits and normal oxygen consumption rate. Our report extends the current picture of morphologic phenotypes associated with mitochondrial cardiomyopathies and confirms the heart as a main target of TSFM dysfunction. The compensatory response detected in patient fibroblasts might explain the tissue-specific expression of TSFM-associated disease
The 'Walking for Wellbeing in the West' randomised controlled trial of a pedometer-based walking programme in combination with physical activity consultation with 12 month follow-up: rationale and study design
- Author
- A Kirk
- A Telford
- AD Pradhan
- AN Jordan
- Annemarie Wright
- AR Hughes
- B Giles-Corti
- B Giles-Corti
- BE Saelens
- BH Marcus
- C Tudor-Locke
- C Tudor-Locke
- Catharine Ward Thompson
- Catherine Millington
- Charlie E Foster
- CL Craig
- Claire F Fitzsimons
- CW Loughlan
- D Ogilvie
- D Watson
- David Ogilvie
- Department of Health
- DM Bravata
- E Erdfelder
- Elisabeth Fenwick
- EuroQol Group
- GA Kelley
- GK Hansson
- Graham Baker
- H Bruunsgaard
- I De Bourdeaudhuij
- J Cohen
- J Kobayashi
- JF Sallis
- JF Sallis
- JM Hallenbeck
- Joanna Inchley
- KJ Calfas
- LD Frank
- M Lowther
- MacDonald G
- MD Vaz de Almeida
- MF Hovell
- ML Kohut
- Myra A Nimmo
- N Humpel
- N Humpel
- N Humpel
- N Mutrie
- N Owen
- Nanette Mutrie
- National Institute for Clinical Excellence
- Park I
- Physical Activity and Health Alliance
- RE Glasgow
- Rebecca Shaw
- RJ Sampson
- Ruth Lowry
- S Landi
- S Thomas
- Scottish Executive
- Scottish Executive
- Scottish Executive
- Scottish Government
- T You
- Tannahill A
- The Scottish Office
- TJ Pikora
- V Braun
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2008
- Field of study
This research was undertaken as part of work carried out by the Scottish Physical Activity Research Collaboration (SPARColl). SPARColl is managed by NHS Health Scotland, hosted by the University of Strathclyde, Glasgow and funded by the Scottish Government.Background: Scotland has a policy aimed at increasing physical activity levels in the population, but evidence on how to achieve this is still developing. Studies that focus on encouraging real world participants to start physical activity in their settings are needed. The Walking for Well-being in theWest study was designed to assess the effectiveness of a pedometer-based walking programme in combination with physical activity consultation. The study was multidisciplinary and based in the community. Walking for Well-being in the West investigated whether Scottish men and women, who were not achieving the current physical activity recommendation, increased and maintained walking behaviour over a 12 month period. This paper outlines the rationale and design of this innovative and pragmatic study. Methods: Participants were randomised into two groups: Group 1: Intervention (pedometer-based walking programme combined with a series of physical activity consultations); Group 2: Waiting list control for 12 weeks (followed by minimal pedometer-based intervention). Physical activity (primary outcome) was measured using pedometer step counts (7 day) and the International Physical Activity Questionnaire (long version). Psychological processes were measured using questionnaires relating to the Transtheoretical Model of Behaviour Change, mood (Positive and Negative Affect Schedule) and quality of life (Euroqol EQ-5D instrument). Physiological measures included anthropometric and metabolic outcomes. Environmental influences were assessed subje ctively (Neighbourhood Quality of Life Survey) and objectively (neighbourhood audit tool and GIS mapping). The qualitative evaluation employed observation, semi-structured interviews and focus groups. A supplementary study undertook an economic evaluation. Discussion: Data analysis is on-going. Walking for Well-being in the West will demonstrate if a pedometer based walking programme, in combination with physicalactivity consultation results in a sustainable increase in walking behaviour in this sample of Scottish adults over a 12 month period. The study will examine the complex relationships between behavioural change, health consequences and the role of the environment, in conjunction with the cost effectiveness of this approach and a detailed insight into the participants' experiences of the intervention. Trial registration: Current Controlled Trials ISRCTN88907382.Publisher PDFPeer reviewe
Type 2 Diabetes Education and Support in a Virtual Environment: A Secondary Analysis of Synchronously Exchanged Social Interaction and Support
- Author
- Publication venue
- 'JMIR Publications Inc.'
- Publication date
- Field of study
CEO Political Ideology and Mergers and Acquisitions Decisions
- Author
- A Agrawal
- A Agrawal
- A Barr
- A C Chui
- Ahmed M. Elnahas
- B B Francis
- B Cadman
- C G Holderness
- D Green
- D Jiang
- D R Carney
- D T Brown
- Dongnyoung Kim
- G Andrade
- G Andrade
- G B Kish
- G D Wilson
- G D Wilson
- G M Phillips
- H Cronqvist
- H Hong
- H Servaes
- I Hutton
- J Gillies
- J H Mulherin
- J Harford
- J J Reuer
- J M Brett
- J T Jost
- J T Jost
- K Fuller
- L Lang
- M Bertrand
- M C Jensen
- M D Cain
- M Giannetti
- M Glasgow
- M J Cooper
- M J Fishman
- N Boubakri
- N G Travlos
- N Kohers
- O Unsal
- P F Wernimont
- P G Berger
- R Comment
- R G Hansen
- R G Hansen
- R J Gilson
- R Rajan
- R Roll
- Ruth Glasgow
- S C Myers
- S Chang
- S Datar
- S Yim
- T C Campbell
- W Adair
- Y Bonaparte
- Y Gorodnichenko
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2016
- Field of study
Novel GFM2 variants associated with early-onset neurological presentations of mitochondrial disease and impaired expression of OXPHOS subunits
- Author
- A Chomyn
- Andrew A. M. Morris
- Axel Neu
- C Miller
- Charlotte L. Alston
- Charu Deshpande
- CL Alston
- D Diodato
- D Soiferman
- D Zhang
- DC Wallace
- DM Kirby
- Holger Prokisch
- Inês A. Barbosa
- Julie Hall
- K Thompson
- Kyle Thompson
- L Galmiche
- L Musante
- Langping He
- LS Kremer
- M Hammarsund
- M Kılıç
- M Scarpelli
- M Sissler
- M Tsuboi
- Maja Hempel
- Michael A. Simpson
- MT Simon
- Robert McFarland
- Robert W. Taylor
- Ruth I. C. Glasgow
- RW Taylor
- S Anderson
- S Brito
- S Fukumura
- S Pearce
- SG Andersson
- TJ Dixon-Salazar
- Tobias B. Haack
- TW O'Brien
- Ulrike Löbel
- ZMA Chrzanowska-Lightowlers
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
A second update on mapping the human genetic architecture of COVID-19
- Author
- Abd Elghafar MS
- Abdel-Aziz M
- Abdelrazik M
- Abdullah MS
- Abe R
- Abe S
- Abel L
- Abel L
- Abernathy C
- Abraham R
- Abraheem A
- Abu Alragheb BO
- Abulail JA
- Acklery A
- Acosta-Herrera M
- Adachi T
- Adachi Y
- Adam R
- Adams C
- Adams K
- Adams N
- Adanini O
- Afifi N
- Afilalo J
- Afilalo M
- Afolabi D
- Afrasiabi Z
- Afset JE
- Agasou A
- Aghemo A
- Agravante K
- Agrawal A
- Agrawal S
- Aguado JM
- Aguilar C
- Aguilar SEV
- Aguilar-Salinas CA
- Aguilera-Albesa S
- Agüero D
- Ahmad HF
- Ahmad N
- Ahmadhaider N
- Ahmed A
- Ahmed C
- Ahram M
- Ai M
- Ain Q
- Aitkin E
- Akeroyd L
- Akhtar MN
- Akinkugbe O
- Al-Ani A
- Al-Ja’afreh MM
- Al-Kadash A
- Al-Kasasbeh MM
- Al-Moasseb H
- Al-Muftah W
- Al-Sarraj Y
- Alamer LM
- Alasdair F
- Alawneh FM
- Alawneh LM
- Albaiceta GM
- Albano G
- Albillos A
- Albrecht W
- Aldridge J
- Alexander P
- Alfonso J
- Alhousani TN
- Ali A
- Ali HH
- Ali IAM
- Ali S
- Aliberti S
- ALjalamdeh M
- Allan A
- Allan E
- Allan J
- Alldis Z
- Allen L
- Allen M
- Allen S
- Allen U
- Allibone S
- Allison KS
- Allouzy SK
- Ally SM
- Almadana V
- Almaden-Boyle C
- Almoguera B
- Alpuche-Aranda C
- AlRawashdeh TJ
- Alsafadi DB
- Alshaer W
- Alsoub FS
- Altabaibeh A
- Alvarez N
- Alvaro A
- Alzuraiqi MR
- Amamio M
- Aman NF
- Amin V
- Amiya S
- Ampuero J
- Anan R
- Anastasescu E
- Andersen S
- Anderson J
- Anderson M
- Anderson P
- Anderson S
- Anderson S
- Anderson T
- Ando A
- Andrade V
- Andreou P
- Andreu-Bernabeu Á
- Andrew A
- Andrew B
- Andrew G
- Andrews J
- Andrews S
- Andrews SJ
- Angelini C
- Ansari AI
- Antcliffe D
- Antoine P
- Antony S
- Anumakonda V
- Anwer M
- Anzai T
- Apetri E
- Aquino M
- Aquino-Gálvez A
- Arai D
- Arakelyan A
- Arana-Arri E
- Arana-Arri E
- Arango C
- Aravindan L
- Arbane G
- Archer K
- Arden T
- Arias SS
- Arif S
- Arimura K
- Armistead J
- Armstrong D
- Armstrong J
- Armstrong L
- Armstrong R
- Arning N
- Arnoldo S
- Arnott A
- Arora J
- Arora M
- Arranz MJ
- Arranz MJ
- Arribas-Rodriguez E
- Artiga M-J
- Arumugam P
- Asakura T
- Asano K
- Aschard H
- Ashby K
- Ashok SR
- Ashraf S
- Ashton L
- Asimakopoulos A
- Aslibekyan S
- Asselta R
- Astin-Chamberlain R
- Atayeva N
- Athanasiou L
- Atkinson EG
- Attwood B
- Atwal I
- Augustin M
- Auld D
- Auld F
- Austin K
- Austin P
- Auton A
- Avetyan D
- Awano N
- Awasthi S
- Ayers A
- Ayo NI
- Ayuso C
- Aziz F
- Aziz N
- Azuma M
- Azuure C
- Azzolini E
- Baba R
- Baba T
- Bacher P
- Badal B
- Badalamenti S
- Baddeley A
- Badia JR
- Badji RM
- Bafitis V
- Bahmer T
- Baikady RR
- Bailey L
- Baillie JK
- Baines D
- Baines K
- Baird T
- Baird Y
- Baker M
- Bakthavatsalam D
- Balaconis MK
- Baldini M
- Balla D
- Bals R
- Bamford A
- Bamford A
- Bamford P
- Banach D
- Banales JM
- Banasik K
- Banasik K
- Bancroft H
- Band G
- Bandera A
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- Bani younis FM
- Bano S
- Baptista D
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- Barberena-Jonas C
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- Barclay C
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- Publication venue
- Nature Research
- Publication date
- 21/06/2023
- Field of study
Whole-genome sequencing reveals host factors underlying critical COVID-19
- Author
- Abd Elghafar Mohamed S.
- Abdel-Aziz Mahmoud
- Abdelrazik Marwa
- Abdollahi Hamed
- Abdullah T.
- Abecasis Goncalo
- Abedalthagafi M.
- Abel Lynn
- Abernathy C.
- Abraheem Azmeralde
- Abul-Husn Noura S.
- Acquilini D.
- Adams C.
- Adams Emma L.
- Adams K.
- Adamsara Alireza
- Adanini Olurenke
- Adeleye O.
- Adra D.
- Afilalo J.
- Afilalo M.
- Afolabi D.
- Afrasiabi Z.
- Agasou A.
- Agrawal Shruti
- Agüero D.
- Ahmad N.
- Ahmadi Saeideh
- Ahmed A.
- Ahmed Cecilia
- Akeroyd L.
- Akhtar M.N.
- Akinkugbe O.
- Aksentijevich Alexandra
- Al-Afghani H.
- Al-Awdah L.
- Alaamery M.
- Alahmadey Z.Z.
- Alaverdian D.
- Alavere H.
- Albader A.
- Albaiceta G.M.
- Albakri J.K.
- AlBardis H.
- Albeladi M.
- Albesher N.
- Albrich W.
- AlDhawi N.
- Aldridge J.
- Aleagha Afshar Etemadi
- Alexander Peter.
- Alfonso J.
- Alghamdi B.
- Alghamdi J.
- Ali A.
- Ali Altaf
- Ali I.A.M.
- Ali Syamlan
- Aliannejad Rasoul
- Aljawini N.
- AlJohani S.
- Alkwai S.
- Allan A.
- Allan E.
- Allan J.
- Alldis Zoe
- Allen L.
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- Publication venue
- Publication date
- 01/01/2022
- Field of study
Altres ajuts: Department of Health and Social Care (DHSC); Illumina; LifeArc; Medical Research Council (MRC); UKRI; Sepsis Research (the Fiona Elizabeth Agnew Trust); the Intensive Care Society, Wellcome Trust Senior Research Fellowship (223164/Z/21/Z); BBSRC Institute Program Support Grant to the Roslin Institute (BBS/E/D/20002172, BBS/E/D/10002070, BBS/E/D/30002275); UKRI grants (MC_PC_20004, MC_PC_19025, MC_PC_1905, MRNO2995X/1); UK Research and Innovation (MC_PC_20029); the Wellcome PhD training fellowship for clinicians (204979/Z/16/Z); the Edinburgh Clinical Academic Track (ECAT) programme; the National Institute for Health Research, the Wellcome Trust; the MRC; Cancer Research UK; the DHSC; NHS England; the Smilow family; the National Center for Advancing Translational Sciences of the National Institutes of Health (CTSA award number UL1TR001878); the Perelman School of Medicine at the University of Pennsylvania; National Institute on Aging (NIA U01AG009740); the National Institute on Aging (RC2 AG036495, RC4 AG039029); the Common Fund of the Office of the Director of the National Institutes of Health; NCI; NHGRI; NHLBI; NIDA; NIMH; NINDS.Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the development of illness requiring critical care or hospitalization after infection with SARS-CoV-2. The GenOMICC (Genetics of Mortality in Critical Care) study enables the comparison of genomes from individuals who are critically ill with those of population controls to find underlying disease mechanisms. Here we use whole-genome sequencing in 7,491 critically ill individuals compared with 48,400 controls to discover and replicate 23 independent variants that significantly predispose to critical COVID-19. We identify 16 new independent associations, including variants within genes that are involved in interferon signalling (IL10RB and PLSCR1), leucocyte differentiation (BCL11A) and blood-type antigen secretor status (FUT2). Using transcriptome-wide association and colocalization to infer the effect of gene expression on disease severity, we find evidence that implicates multiple genes-including reduced expression of a membrane flippase (ATP11A), and increased expression of a mucin (MUC1)-in critical disease. Mendelian randomization provides evidence in support of causal roles for myeloid cell adhesion molecules (SELE, ICAM5 and CD209) and the coagulation factor F8, all of which are potentially druggable targets. Our results are broadly consistent with a multi-component model of COVID-19 pathophysiology, in which at least two distinct mechanisms can predispose to life-threatening disease: failure to control viral replication; or an enhanced tendency towards pulmonary inflammation and intravascular coagulation. We show that comparison between cases of critical illness and population controls is highly efficient for the detection of therapeutically relevant mechanisms of disease
Additional file 17 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
- Author
- Aadahl Mette
- Abbas Shahid
- Abecasis Goncalo
- Academy of Scientific and Innovative Research (AcSIR)
- Adair Linda S.
- Adams Hieab H. H.
- Adeyemo Adebowale A.
- Agency for Science Technology and Research (A*STAR)
- Aguilar-Salinas Carlos A.
- Akiyama Masato
- Al-Mulla Fahd
- Alexandria University
- Algebra University College
- Arbeeva Liubov
- Arctic Centre Univ. of Groningen
- Arnett Donna K.
- Asselbergs Folkert W.
- Assimes Themistocles L.
- Atlanta VA Health Care System
- Attia John
- Banas Bernhard
- Bandinelli Stefania
- Baras Aris
- Barts and The London School of Medicine and Dentistry
- Bayyana Swati
- Bechayda Sonny Augustin
- Beijing Institute for Brain Disorders
- Beijing Tongren Hospital Capital Medical University
- Benjamins Jan W.
- Bennett David A.
- Bentley Amy R.
- Berlin Institute of Health
- Beulens Joline W. J.
- Bharadwaj Dwaipayan
- Bhatti Konain Fatima
- BHF Glasgow Cardiovascular Research Centre Faculty of Medicine
- Bielak Lawrence F.
- Biino Ginevra
- Bis Joshua C.
- Bispebjerg and Frederiksberg Hospital
- Bjerregaard Anne A.
- Black Corri
- Blood Institute's and Boston University's Framingham Heart Study
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- Bornholms Hospital
- Boston University School of Public Health
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- Schunkert Heribert
- Scott Rodney J.
- Sengupta Dhriti
- Sever Peter
- Shimane University School of Medicine
- Shin Jae Hun
- Shu Xiao-Ou
- Sim Xueling
- Simonsick Eleanor
- Singapore Eye Research Institute
- Singapore Immunology Network (SIgN) Agency for Science Technology and Research Singapore, Biopolis
- Slieker Roderick C.
- Smith Blair H.
- Smith Jennifer A.
- Smyth Laura J.
- Snieder Harold
- Southam Lorraine
- Southern University of Science and Technology
- Spector Tim D.
- Spracklen Cassandra N.
- St George's University of London
- St. Olavs University Hospital
- Stanford University
- Stanford University School of Medicine
- Stark Klaus J.
- Stefansson Kari
- Strachan David P.
- Strangeways Research Laboratory
- Stringham Heather M.
- Sun Yan V.
- Sung Yun Ju
- Sungkyunkwan University
- Sungkyunkwan University School of Medicine
- Surakka Ida
- Swiss Institute of Bioinformatics
- Sygehus Lillebælt
- SYNLAB Medizinisches Versorgungszentrum Weiden GmbH
- Tabara Yasuharu
- Tai EShyong
- Taichung Veterans General Hospital
- Taipei Veterans General Hospital
- Takayama Jun
- Takeuchi Fumihiko
- Tamiya Gen
- Tampere University Hospital
- Tampereen Yliopisto
- Tang Hua
- Tardif Jean-Claude
- Technical University Munich
- Technical University of Munich
- Terao Chikashi
- Terzikhan Natalie
- Thanaraj Thangavel Alphonse
- The Institute for Translational Genomics and Population Sciences
- The University of Newcastle
- the University of Texas Health Science
- The University of Texas Health Science Center at Houston
- The University of Tokyo
- The University of Western Australia
- Theusch Elizabeth
- Thiery Joachim
- Thorleifsson Gudmar
- Thorsteinsdottir Unnur
- Timmers Paul R. H. J.
- Timpson Nicholas J.
- Tohoku University
- Tongji Medical College
- Traunstein Hospital
- Trembath Richard C.
- Trivedi Bhavi
- Trompet Stella
- Tsao Noah L.
- Tsao Philip S.
- Turku University Hospital and University of Turku
- Turman Constance
- Tusié-Luna Teresa
- Tönjes Anke
- Universidad Adolfo Ibáñez
- Universidad de Granada
- Universidad Nacional Autónoma de México
- University Greifswald
- University Hospital of Southern Denmark
- University Medical Center Groningen
- University Medical Center Utrecht
- University Medicine Greifswald
- University of Aberdeen
- University of Alabama Birmingham
- University of Bergen
- University of Bristol
- University of Bristol Faculty of Medicine and Dentistry
- University of California Los Angeles
- University of California San Francisco
- University of College London
- University of Colorado Denver
- University of Copenhagen
- University of Copenhagen Faculty of Health Sciences
- University of Dundee
- University of Eastern Finland
- University of Edinburgh
- University of Essen
- University of Essex
- University of Exeter
- University of Exeter Medical School
- University of Glasgow
- University of Gothenburg
- University of Gothenburg Sahlgrenska Academy
- University of Groningen
- University of Heidelberg
- University of Helsinki
- University of Houston
- University of Iceland
- University of Illinois College of Medicine
- University of Kelaniya
- University of Lausanne
- University of Leicester
- University of Manchester
- University of Massachusetts
- University of Massachusetts Boston
- University of Melbourne
- University of Michigan
- University of Michigan Medical School
- University of Michigan School of Public Health
- University of Mississippi Medical Center
- University of Montreal
- University of Newcastle Faculty of Medicine and Health Sciences
- University of Newcastle Australia
- University of North Carolina
- University of Oslo
- University of Oulu
- University of Oxford Medical Sciences Division
- University of Pennsylvania
- University of Pennsylvania Perelman School of Medicine
- University of Pittsburgh
- University of Pittsburgh Graduate School of Public Health
- University of Queensland
- University of Regensburg
- University of San Carlos
- University of Science and Technology of China
- University of South Carolina
- University of Southern Denmark
- University of Split School of Medicine
- University of Surrey
- University of Sydney
- University of Texas Health Science Center at Houston
- University of the Witwatersrand
- University of the Witwatersrand Faculty of Health Sciences
- University of Toronto
- University of Turku
- University of Utah School of Medicine
- University of Virginia
- University of Washington School of Medicine
- University of Washington Seattle
- University of Zaragoza
- Universität Potsdam
- Universitätsklinikum Regensburg
- Université de Montréal
- UPMC Hillman Cancer Center
- Uppsala University
- VA Boston Healthcare System
- VA Palo Alto Health Care System
- Vaccargiu Simona
- van Dam Rob M.
- van der Harst Pim
- van der Laan Sander W.
- van der Most Peter J.
- van Dijk Ko Willems
- van Duijn Cornelia M.
- van Heel David A.
- van Meurs Joyce B. J.
- van Setten Jessica
- Vanderbilt University Medical Center
- Vazquez-Moreno Miguel
- Vedantam Sailaja
- Verma Anurag
- Verve Therapeutics
- Verweij Niek
- Vestergaard Henrik
- Veturi Yogasudha
- Villalpando Clicerio Gonzalez
- Virgen de las Nieves University Hospital
- Vitart Veronique
- Vrije Universiteit Amsterdam de Boelelaan
- VU University Medical Center
- Völzke Henry
- Walker Mark
- Walters Robin G.
- Wang Carol A.
- Wang Chaolong
- Wang Jun-Sing
- Wang Ya Xing
- Wang Yuxuan
- Wang Zeyuan
- Wang Zhe
- Wareham Nicholas J.
- Warner Sophie C.
- Warren Helen R.
- Washington University in St. Louis
- Washington University School of Medicine in St. Louis
- Watkins Hugh
- Wei Wei-Qi
- Wei Wen B.
- Weill Cornell Medicine-Qatar
- Weir David R.
- Weiss Stefan
- Wellcome Sanger Institute
- Wellcome Trust Centre for Human Genetics
- Wenzhou Medical University
- Westlake Laboratory of Life Sciences and Biomedicine
- Westlake University
- Whitfield John B.
- Wickremasinghe Ananda R.
- Widén Elisabeth
- Wielscher Matthias
- Wild Sarah H.
- Willemsen Allegonda H. M.
- Willer Cristen J.
- Wilson James F.
- Wilson James G.
- Wilson Peter W. F.
- Winkler Thomas W.
- Wojczynski Mary K.
- Wong Andrew
- Wong Tien-Yin
- Woo Jeong-Taek
- Wood Andrew R.
- Wu Jer-Yuarn
- Wu Kuan-Han H.
- Xia Rui
- Xue Chao
- Yamamoto Masayuki
- Yang Bin
- Yang Jian
- Yang Jingyun
- Yao Jie
- Yin Xianyong
- Yokota Mitsuhiro
- Yong Loo Lin School of Medicine
- Yonsei University
- Yoon Kyungheon
- Yousri Noha A.
- Yu Ketian
- Yuan Jian-Min
- Zajac Greg J. M.
- Zeggini Eleftheria
- Zeng Lingyao
- Zhang Jifeng
- Zhang Weihua
- Zhao Jing-Hua
- Zhao Wei
- Zheng Wei
- Zhou Wei
- Zhu Xiang
- Zhu Xiaofeng
- Zilhao Nuno R.
- Zimmermann Martina E.
- Zmuda Joseph M.
- Zonderman Alan B.
- Åsvold Bjørn Olav
- Publication venue
- figshare
- Publication date
- 01/01/2023
- Field of study
Additional file 17: Table S9. PheWAS UKB-MVP meta-analysis results for each index lipid variant at Bonferroni threshold for multiple testing
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