Fracture behavior in Cu46.5Zr46.5Al7 and Cu46.5Zr41.5Al7Y5 bulk metallic glasses

The interplay between chemical composition, plastic behavior, and fracture modes of Cu46.5Zr46.5Al7 and Cu46.5Zr41.5Al7Y5 bulk metallic glasses (BMGs) was investigated by compression tests and fracture surfaces analyses. The aim was to explore the possibility of coupling physical, chemical, and hardness properties, with adequate macroscopic compressive plasticity. Cylindrical test samples, having a height-to-diameter ratio equal to 2, were machined and ground from as-cast bars and were tested in compression between lubricated plates, the displacement being measured by a clip-gage inserted between the plates. Y free BMG engineering stress-strain curves show a plastic behavior consisting of successive sudden stress drops and linear reloading segments. A detailed analysis of these features was performed to yield a correlation between the plastic deformation steps and the released elastic energy associated with each serratio

A Hybrid Monte Carlo Method for Surface Growth Simulations

We introduce an algorithm for treating growth on surfaces which combines important features of continuum methods (such as the level-set method) and Kinetic Monte Carlo (KMC) simulations. We treat the motion of adatoms in continuum theory, but attach them to islands one atom at a time. The technique is borrowed from the Dielectric Breakdown Model. Our method allows us to give a realistic account of fluctuations in island shape, which is lacking in deterministic continuum treatments and which is an important physical effect. Our method should be most important for problems close to equilibrium where KMC becomes impractically slow.Comment: 4 pages, 5 figure

Lines on projective varieties and applications

The first part of this note contains a review of basic properties of the variety of lines contained in an embedded projective variety and passing through a general point. In particular we provide a detailed proof that for varieties defined by quadratic equations the base locus of the projective second fundamental form at a general point coincides, as a scheme, with the variety of lines. The second part concerns the problem of extending embedded projective manifolds, using the geometry of the variety of lines. Some applications to the case of homogeneous manifolds are included.Comment: 15 pages. One example removed; one remark and some references added; typos correcte

The fate of nitrogen during agricultural intensification in East Africa: nitrogen budgets in contrasting agroecosystems

Open Access ArticleThe intensification of agricultural systems in sub-Saharan Africa (SSA) is necessary to reduce poverty and improve food security, but increased nutrient applications in smallholder systems could have negative consequences for water quality, greenhouse gas emissions, and air quality. We tracked nitrogen (N) inputs and measured maize (Zea mays) biomass, grain yields, N leaching, and nitric oxide (NO) and nitrous oxide fluxes from a clayey soil in Yala, Kenya and a sandy soil in Tumbi, Tanzania, with application rates of 0, 50, 75, 100, 150, and 200 kg N ha−1 yr−1 over two cropping seasons. Maize yields were 4.5 times higher in Yala than Tumbi, but yields plateaued at both sites with fertilizer applications at or above 100 kg N ha−1 yr−1. Partial N budgets in Yala were typically negative, meaning more N was exported in maize biomass plus grain or lost from the system than was added in fertilizer. In Tumbi, N budgets were negative at lower fertilizer levels but positive at higher fertilizer levels. At both sites most (96%) of the N was lost through maize biomass/grain removal and N leaching. Fertilizer additions at or less than 50 kg N ha−1 yr−1 on these two contrasting sites resulted in minor gaseous N losses, and fertilizer additions less than 200 kg N ha−1 yr−1 caused relatively little change to N leaching losses. This indicates that the modest increases in fertilizer use required to improve maize yields will not greatly increase cropland N losses. Plain Language Summary Crop yields in smallholder agriculture across sub-Saharan Africa are low but could be increased by greater applications of nitrogen fertilizer. However, greater use of nitrogen fertilizer creates potential for higher emissions of nitrogen trace gases and nitrogen leaching losses. This study added nitrogen fertilizer doses (0, 50, 75, 100, 150, and 200 kg of nitrogen per hectare) to maize cropland in two smallholder farming sites, one on clay-rich soils in Kenya and one on sandy soils in Tanzania. It tracked removal of nitrogen fertilizer via harvested maize and losses as nitrous oxide (a greenhouse gas), NO (an air pollutant), and leaching of soil solution. Yields were 4.5 times higher on the clayey soil; yields plateaued at nitrogen application above 100 kg per hectare. Leaching losses far exceeded gaseous losses at both sites: 96% of nitrogen was removed in harvested crops and soil solution. Nitrogen additions at or below 50 kg of nitrogen per hectare led to minor increases in gaseous nitrogen losses and additions less than 200 kg of nitrogen per hectare did not increase soil solution losses. This indicates that the modest increases in fertilizer use required to improve maize yields will not greatly increase cropland nitrogen losses

Characterization of Antibodies against Receptor Activity-Modifying Protein 1 (RAMP1): A Cautionary Tale

Calcitonin gene-related peptide (CGRP) is a key component of migraine pathophysiology, yielding effective migraine therapeutics. CGRP receptors contain a core accessory protein subunit: receptor activity-modifying protein 1 (RAMP1). Understanding of RAMP1 expression is incomplete, partly due to the challenges in identifying specific and validated antibody tools. We profiled antibodies for immunodetection of RAMP1 using Western blotting, immunocytochemistry and immunohistochemistry, including using RAMP1 knockout mouse tissue. Most antibodies could detect RAMP1 in Western blotting and immunocytochemistry using transfected cells. Two antibodies (844, ab256575) could detect a RAMP1-like band in Western blots of rodent brain but not RAMP1 knockout mice. However, cross-reactivity with other proteins was evident for all antibodies. This cross-reactivity prevented clear conclusions about RAMP1 anatomical localization, as each antibody detected a distinct pattern of immunoreactivity in rodent brain. We cannot confidently attribute immunoreactivity produced by RAMP1 antibodies (including 844) to the presence of RAMP1 protein in immunohistochemical applications in brain tissue. RAMP1 expression in brain and other tissues therefore needs to be revisited using RAMP1 antibodies that have been comprehensively validated using multiple strategies to establish multiple lines of convincing evidence. As RAMP1 is important for other GPCR/ligand pairings, our results have broader significance beyond the CGRP field

RG flows from Spin(7), CY 4-fold and HK manifolds to AdS, Penrose limits and pp waves

We obtain explicit realizations of holographic renormalization group (RG) flows from M-theory, from E^{2,1} \times Spin(7) at UV to AdS_4 \times \tilde{S^7} (squashed S^7) at IR, from E^{2,1} \times CY4 at UV to AdS_4 \times Q^{1,1,1} at IR, and from E^{2,1} \times HK (hyperKahler) at UV to AdS_4 \times N^{0,1,0} at IR. The dual type IIA string theory configurations correspond to D2-D6 brane systems where D6 branes wrap supersymmetric four-cycles. We also study the Penrose limits and obtain the pp-wave backgrounds for the above configurations. Besides, we study some examples of non-supersymmetric and supersymmetric flows in five-dimensional gauge theories.Comment: 42 pages, 6 eps figures, typos and misprints correcte

Plastic localization phenomena in a Mn-alloyed austenitic steel

A 0.5 wt pct C, 22 wt pct Mn austenitic steel, recently proposed for fabricating automotive body structures by cold sheet forming, exhibits plastic localizations (PLs) during uniaxial tensile tests, yet showing a favorable overall strength and ductility. No localization happens during biaxial Erichsen cupping tests. Full-thickness tensile and Erichsen specimens, cut from as-produced steel sheets, were polished and tested at different strain rates. During the tensile tests, the PL phenomena consist first of macroscopic deformation bands traveling along the tensile axis, and then of a series of successive stationary deformation bands, each adjacent to the preceding ones; both types of bands involve the full specimen width and yield a macroscopically observable surface relief. No comparable surface relief was observed during the standard Erichsen tests. Because the stress state is known to influence PL phenomena, reduced-width Erichsen tests were performed on polished sheet specimens, in order to explore the transition from biaxial to uniaxial loading; surface relief lines were observed on a 20-mm-wide specimen, but not on wider ones

Anisotropic flow of charged hadrons, pions and (anti-)protons measured at high transverse momentum in Pb-Pb collisions at sNN=2.76\sqrt{s_{\rm NN}}=2.76 TeV

The elliptic, $v_2$, triangular, $v_3$, and quadrangular, $v_4$, azimuthal anisotropic flow coefficients are measured for unidentified charged particles, pions and (anti-)protons in Pb-Pb collisions at $\sqrt{s_{\rm NN}} = 2.76$ TeV with the ALICE detector at the Large Hadron Collider. Results obtained with the event plane and four-particle cumulant methods are reported for the pseudo-rapidity range $|\eta|<0.8$ at different collision centralities and as a function of transverse momentum, $p_{\rm T}$, out to $p_{\rm T}=20$ GeV/$c$. The observed non-zero elliptic and triangular flow depends only weakly on transverse momentum for $p_{\rm T}>8$ GeV/$c$. The small $p_{\rm T}$ dependence of the difference between elliptic flow results obtained from the event plane and four-particle cumulant methods suggests a common origin of flow fluctuations up to $p_{\rm T}=8$ GeV/$c$. The magnitude of the (anti-)proton elliptic and triangular flow is larger than that of pions out to at least $p_{\rm T}=8$ GeV/$c$ indicating that the particle type dependence persists out to high $p_{\rm T}$.Comment: 16 pages, 5 captioned figures, authors from page 11, published version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/186

Centrality dependence of charged particle production at large transverse momentum in Pb-Pb collisions at sNN=2.76\sqrt{s_{\rm{NN}}} = 2.76 TeV

The inclusive transverse momentum ($p_{\rm T}$) distributions of primary charged particles are measured in the pseudo-rapidity range $|\eta|<0.8$ as a function of event centrality in Pb-Pb collisions at $\sqrt{s_{\rm{NN}}}=2.76$ TeV with ALICE at the LHC. The data are presented in the $p_{\rm T}$ range $0.15<p_{\rm T}<50$ GeV/$c$ for nine centrality intervals from 70-80% to 0-5%. The Pb-Pb spectra are presented in terms of the nuclear modification factor $R_{\rm{AA}}$ using a pp reference spectrum measured at the same collision energy. We observe that the suppression of high-$p_{\rm T}$ particles strongly depends on event centrality. In central collisions (0-5%) the yield is most suppressed with $R_{\rm{AA}}\approx0.13$ at $p_{\rm T}=6$-7 GeV/$c$. Above $p_{\rm T}=7$ GeV/$c$, there is a significant rise in the nuclear modification factor, which reaches $R_{\rm{AA}} \approx0.4$ for $p_{\rm T}>30$ GeV/$c$. In peripheral collisions (70-80%), the suppression is weaker with $R_{\rm{AA}} \approx 0.7$ almost independently of $p_{\rm T}$. The measured nuclear modification factors are compared to other measurements and model calculations.Comment: 17 pages, 4 captioned figures, 2 tables, authors from page 12, published version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/284

Measurement of charm production at central rapidity in proton-proton collisions at s=2.76\sqrt{s} = 2.76 TeV

The $p_{\rm T}$-differential production cross sections of the prompt (B feed-down subtracted) charmed mesons D$^0$, D$^+$, and D$^{*+}$ in the rapidity range $|y|<0.5$, and for transverse momentum $1< p_{\rm T} <12$ GeV/$c$, were measured in proton-proton collisions at $\sqrt{s} = 2.76$ TeV with the ALICE detector at the Large Hadron Collider. The analysis exploited the hadronic decays D$^0 \rightarrow$K$\pi$, D$^+ \rightarrow$K$\pi\pi$, D$^{*+} \rightarrow$D$^0\pi$, and their charge conjugates, and was performed on a $L_{\rm int} = 1.1$ nb$^{-1}$ event sample collected in 2011 with a minimum-bias trigger. The total charm production cross section at $\sqrt{s} = 2.76$ TeV and at 7 TeV was evaluated by extrapolating to the full phase space the $p_{\rm T}$-differential production cross sections at $\sqrt{s} = 2.76$ TeV and our previous measurements at $\sqrt{s} = 7$ TeV. The results were compared to existing measurements and to perturbative-QCD calculations. The fraction of cdbar D mesons produced in a vector state was also determined.Comment: 20 pages, 5 captioned figures, 4 tables, authors from page 15, published version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/307