Collective excitations of atomic Bose-Einstein condensates

We apply linear-response analysis of the Gross-Pitaevskii equation to obtain the excitation frequencies of a Bose-Einstein condensate confined in a time-averaged orbiting potential trap. Our calculated values are in excellent agreement with those observed in a recent experiment.Comment: 11 pages, 2 Postscript figures, uses psbox.tex for automatic figure inclusion. More info at http://amo.phy.gasou.edu/bec.htm

Moisture - Gravity Wave Interactions in a Multiscale Environment

Starting from the conservation laws for mass, momentum and energy together with a three species, bulk microphysic model, a model for the interaction of internal gravity waves and deep convective hot towers is derived by using multiscale asymptotic techniques. From the resulting leading order equations, a closed model is obtained by applying weighted averages to the smallscale hot towers without requiring further closure approximations. The resulting model is an extension of the linear, anelastic equations, into which moisture enters as the area fraction of saturated regions on the microscale with two way coupling between the large and small scale. Moisture reduces the effective stability in the model and defines a potential temperature sourceterm related to the net effect of latent heat release or consumption by microscale up- and downdrafts. The dispersion relation and group velocity of the system is analyzed and moisture is found to have several effects: It reduces energy transport by waves, increases the vertical wavenumber but decreases the slope at which wave packets travel and it introduces a lower horizontal cutoff wavenumber, below which modes turn into evanescent. Further, moisture can cause critical layers. Numerical examples for steady-state and time-dependent mountain waves are shown and the effects of moisture on these waves are investigated

HIV Exploits Antiviral Host Innate GCN2-ATF4 Signaling for Establishing Viral Replication Early in Infection.

Antiviral innate host defenses against acute viral infections include suppression of host protein synthesis to restrict viral protein production. Less is known about mechanisms by which viral pathogens subvert host antiviral innate responses for establishing their replication and dissemination. We investigated early innate defense against human immunodeficiency virus (HIV) infection and viral evasion by utilizing human CD4+ T cell cultures in vitro and a simian immunodeficiency virus (SIV) model of AIDS in vivo Our data showed that early host innate defense against the viral infection involves GCN2-ATF4 signaling-mediated suppression of global protein synthesis, which is exploited by the virus for supporting its own replication during early viral infection and dissemination in the gut mucosa. Suppression of protein synthesis and induction of protein kinase GCN2-ATF4 signaling were detected in the gut during acute SIV infection. These changes diminished during chronic viral infection. HIV replication induced by serum deprivation in CD4+ T cells was linked to the induction of ATF4 that was recruited to the HIV long terminal repeat (LTR) to promote viral transcription. Experimental inhibition of GCN2-ATF4 signaling either by a specific inhibitor or by amino acid supplementation suppressed the induction of HIV expression. Enhancing ATF4 expression through selenium administration resulted in reactivation of latent HIV in vitro as well as ex vivo in the primary CD4+ T cells isolated from patients receiving suppressive antiretroviral therapy (ART). In summary, HIV/SIV exploits the early host antiviral response through GCN2-ATF4 signaling by utilizing ATF4 for activating the viral LTR transcription to establish initial viral replication and is a potential target for HIV prevention and therapy.IMPORTANCE Understanding how HIV overcomes host antiviral innate defense response in order to establish infection and dissemination is critical for developing prevention and treatment strategies. Most investigations focused on the viral pathogenic mechanisms leading to immune dysfunction following robust viral infection and dissemination. Less is known about mechanisms that enable HIV to establish its presence despite rapid onset of host antiviral innate response. Our novel findings provide insights into the viral strategy that hijacks the host innate response of the suppression of protein biosynthesis to restrict the virus production. The virus leverages transcription factor ATF4 expression during the GCN2-ATF4 signaling response and utilizes it to activate viral transcription through the LTR to support viral transcription and production in both HIV and SIV infections. This unique viral strategy is exploiting the innate response and is distinct from the mechanisms of immune dysfunction after the critical mass of viral loads is generated

NGC 6738: not a real open cluster

A photometric, astrometric and spectroscopic investigation of the poorly studied open cluster NGC 6738 has been performed in order to ascertain its real nature. NGC 6738 is definitely not a physical stellar ensemble: photometry does not show a defined mean sequence, proper motions and radial velocities are randomly distributed, spectro-photometric parallaxes range between 10 and 1600 pc, and the apparent luminosity function is identical to that of the surrounding field. NGC 6738 therefore appears to be an apparent concentration of a few bright stars projected on patchy background absorption.Comment: A&A, in press (compared with first submission to astro-ph, now Table 2 and Figure 4 are replaced with corrected versions

Dynamic Aperture Studies for the Transfer Line From FLUTE to cSTART

The compact STorage ring for Accelerator Research and Technology cSTART project will deliver a new KIT accelerator test facility for the application of novel acceleration techniques and diagnostics. The goal is to demonstrate storing an electron beam of a Laser Plasma Accelerator (LPA) in a compact circular accelerator for the first time. Before installing an LPA, the Far-Infrared Linac and Test Experiment (FLUTE) will serve as a full energy injector for the compact storage ring, providing stable bunches with a length down to a few femtoseconds. The transport of the bunches from FLUTE to the cSTART storage ring requires a transfer line which includes horizontal, vertical and coupled deflections which leads to coupling of the dynamics in the two transverse planes. In order to realize ultra-short bunch lengths at the end of the transport line, it relies on special optics which invokes high and negative dispersion. This contribution presents dynamic aperture studies based on six-dimensional tracking through the lattice of the transfer line

Status of the FLUTE RF System Upgrade

FLUTE (Ferninfrarot Linac- Und Test-Experiment) is a compact versatile linac-based accelerator test facility at KIT. Its main goal is to serve as a platform for a variety of accelerator studies and to generate strong ultra-short THz pulses for photon science. It will also serve as an injector for a Very Large Acceptance compact Storage Ring (VLA-cSR), which will be realized at KIT in the framework of the compact STorage Ring for Accelerator Research and Technology (cSTART) project. To achieve acceleration of electrons in the RF photoinjector and LINAC (from FLUTE) with high stability, it is necessary to provide stable RF power. For this goal, an upgrade of the existing RF system design has been proposed and is currently being implemented. This contribution will report on the updated RF system design and the commissioning status of the new RF system components

Coherent Dynamics of Vortex Formation in Trapped Bose-Einstein Condensates

Simulations of a rotationally stirred condensate show that a regime of simple behaviour occurs in which a single vortex cycles in and out of the condensate. We present a simple quantitative model of this behaviour, which accurately describes the full vortex dynamics, including a critical angular speed of stirring for vortex formation. A method for experimentally preparing a condensate in a central vortex state is suggested.Comment: 4 pages, 4 figures, REVTeX 3.1; Submitted to Physical Review Letters (5 February 1999); See http://www.physics.otago.ac.nz/research/bec/vortex for MPEG movies and further information; Accepted for Physical Review Letters (24 June 1999); Changes: updated Figs 1 and 2 (new style), minor typos fixed, more discussion at en

Beam Dynamics Observations at Negative Momentum Compaction Factors at KARA

For the development of future synchrotron light sources new operation modes often have to be considered. One such mode is the operation with a negative momentum compaction factor to provide the possibility of increased dynamic aperture. For successful application in future light sources, the influence of this mode has to be investigated. At the KIT storage ring KARA (Karlsruhe Research Accelerator), operation with negative momentum compaction has been implemented and the dynamics can now be investigated. Using a variety of high-performance beam diagnostics devices it is possible to observe the beam dynamics under negative momentum compaction conditions. This contribution presents different aspects of the results of these investigations in the longitudinal and transversal plane