Optimization of multivariate analysis for IACT stereoscopic systems

Multivariate methods have been recently introduced and successfully applied for the discrimination of signal from background in the selection of genuine very-high energy gamma-ray events with the H.E.S.S. Imaging Atmospheric Cerenkov Telescope. The complementary performance of three independent reconstruction methods developed for the H.E.S.S. data analysis, namely Hillas, model and 3D-model suggests the optimization of their combination through the application of a resulting efficient multivariate estimator. In this work the boosted decision tree method is proposed leading to a significant increase in the signal over background ratio compared to the standard approaches. The improved sensitivity is also demonstrated through a comparative analysis of a set of benchmark astrophysical sources.Comment: 10 pages, 8 figures, 3 tables, accepted for publication in Astroparticle Physic

Improved sensitivity of H.E.S.S.-II through the fifth telescope focus system

The Imaging Atmospheric Cherenkov Telescope (IACT) works by imaging the very short flash of Cherenkov radiation generated by the cascade of relativistic charged particles produced when a TeV gamma ray strikes the atmosphere. This energetic air shower is initiated at an altitude of 10-30 km depending on the energy and the arrival direction of the primary gamma ray. Whether the best image of the shower is obtained by focusing the telescope at infinity and measuring the Cherenkov photon angles or focusing on the central region of the shower is a not obvious question. This is particularly true for large size IACT for which the depth of the field is much smaller. We address this issue in particular with the fifth telescope (CT5) of the High Energy Stereoscopic System (H.E.S.S.); a 28 m dish large size telescope recently entered in operation and sensitive to an energy threshold of tens of GeVs. CT5 is equipped with a focus system, its working principle and the expected effect of focusing depth on the telescope sensitivity at low energies (50-200 GeV) is discussed.Comment: In Proceedings of the 33rd International Cosmic Ray Conference (ICRC2013), Rio de Janeiro (Brazil

A Fixed-Target ExpeRiment at the LHC (AFTER@LHC) : luminosities, target polarisation and a selection of physics studies

We report on a future multi-purpose fixed-target experiment with the proton or lead ion LHC beams extracted by a bent crystal. The multi-TeV LHC beams allow for the most energetic fixed-target experiments ever performed. Such an experiment, tentatively named AFTER for "A Fixed-Target ExperRiment", gives access to new domains of particle and nuclear physics complementing that of collider experiments, in particular at RHIC and at the EIC projects. The instantaneous luminosity at AFTER using typical targets surpasses that of RHIC by more than 3 orders of magnitude. Beam extraction by a bent crystal offers an ideal way to obtain a clean and very collimated high-energy beam, without decreasing the performance of the LHC. The fixed-target mode also has the advantage of allowing for spin measurements with a polarised target and for an access over the full backward rapidity domain up to xF ~ - 1. Here, we elaborate on the reachable luminosities, the target polarisation and a selection of measurements with hydrogen and deuterium targets.Comment: 6 pages. Proceedings of the Sixth International Conference on Quarks and Nuclear Physics QNP2012 (16-20 April 2012, Ecole Polytechnique, Palaiseau,France

Spin physics at A Fixed-Target ExpeRiment at the LHC (AFTER@LHC)

We outline the opportunities for spin physics which are offered by a next generation and multi-purpose fixed-target experiment exploiting the proton LHC beam extracted by a bent crystal. In particular, we focus on the study of single transverse spin asymetries with the polarisation of the target.Comment: Contributed to the 20th International Spin Physics Symposium, SPIN2012, 17-22 September 2012, Dubna, Russia, 4 pages, LaTe

Prospectives for A Fixed-Target ExpeRiment at the LHC: AFTER@LHC

We argue that the concept of a multi-purpose fixed-target experiment with the proton or lead-ion LHC beams extracted by a bent crystal would offer a number of ground-breaking precision-physics opportunities. The multi-TeV LHC beams will allow for the most energetic fixed-target experiments ever performed. The fixed-target mode has the advantage of allowing for high luminosities, spin measurements with a polarised target, and access over the full backward rapidity domain --uncharted until now-- up to x_F ~ -1.Comment: 6 pages, 1 table, LaTeX. Proceedings of the 36th International Conference on High Energy Physics (ICHEP2012), 4-11 July 2012, Melbourne, Australi

Postoperative urinary retention:Risk factors, bladder filling rate and time to catheterization: an observational study as part of a randomized controlled trial

Background: Knowledge of risk factors for postoperative urinary retention may guide appropriate and timely urinary catheterization. We aimed to determine independent risk factors for postoperative urinary catheterization in general surgical patients. In addition, we calculated bladder filling rate and assessed the time to spontaneous voiding or catheterization. We used the patients previously determined individual maximum bladder capacity as threshold for urinary catheterization.Methods: Risk factors for urinary catheterization were prospectively determined in 936 general surgical patients. Patients were at least 18 years of age and operated under general or spinal anesthesia without the need for an indwelling urinary catheter. Patients measured their maximum bladder capacity preoperatively at home, by voiding in a calibrated bowl after a strong urge that could no longer be ignored. Postoperatively, bladder volumes were assessed hourly with ultrasound. When patients reached their maximum bladder capacity and were unable to void, they were catheterized by the nursing staff. Bladder filling rate and time to catheterization were determined.Results: Spinal anesthesia was the main independent modifiable risk factor for urinary catheterization (hyperbaric bupivacaine, relative risk 8.1, articaine RR 3.1). Unmodifiable risk factors were a maximum bladder capacity &lt;500 mL (RR 6.7), duration of surgery &gt;= 60 min (RR 5.5), first scanned bladder volume at the Post Anesthesia Care Unit &gt;= 250mL (RR 2.1), and age &gt;= 60 years (RR 2.0). Urine production varied from 100 to 200 mL/h. Catheterization or spontaneous voiding took place approximately 4 h postoperatively.Conclusion: Spinal anesthesia, longer surgery time, and older age are the main risk factors for urinary retention catheterization. Awareness of these risk factors, regularly bladder volume scanning (at least every 3 h) and using the individual maximum bladder capacity as volume threshold for urinary catheterization may avoid unnecessary urinary catheterization and will prevent bladder overdistention with the attendant risk of lower urinary tract injury.</p

Kinetics of mouse jejunum radiosensitization by 2',2'-difluorodeoxycytidine (gemcitabine) and its relationship with pharmacodynamics of DNA synthesis inhibition and cell cycle redistribution in crypt cells.

Gemcitabine (dFdC), a deoxycitidine nucleoside analogue, inhibits DNA synthesis and repair of radiation-induced chromosome breaks in vitro, radiosensitizes various human and mouse cells in vitro and shows clinical activity in several tumours. Limited data are however available on the effect of dFdC on normal tissue radiotolerance and on factors associated with dFdC's radiosensitization in vivo. The purpose of this study was to determine the effect of dFdC on mouse jejunum radiosensitization and to investigate the kinetics of DNA synthesis inhibition and cell cycle redistribution in the jejunal crypts as surrogates of radiosensitization in vivo. For assessment of jejunum tolerance, the mice were irradiated on the whole body with 60Co gamma rays (3.5-18 Gy single dose) with or without prior administration of dFdC (150 mg kg-1). Jejunum tolerance was evaluated by the number of regenerated crypts per circumference at 86 h after irradiation. For pharmacodynamic studies, dFdC (150 or 600 mg kg-1) was given i.p. and jejunum was harvested at various times (0-48 h), preceded by a pulse BrdUrd labelling. Labelled cells were detected by immunohistochemistry on paraffin-embedded sections. DNA synthesis was inhibited within 3 h after dFdC administration. After an early wave of apoptosis (3-6 h), DNA synthesis recovered by 6 h, and crypt cells became synchronized. At 48 h, the labelling index returned almost to background level. At a level of 40 regenerated crypts, radiosensitization was observed for a 3 h time interval (dose modification factor of 1.3) and was associated with DNA synthesis inhibition, whereas a slight radioprotection was observed for a 48-h time interval (dose modification factor of 0.9) when DNA synthesis has reinitiated. In conclusion, dFdC altered the radioresponse of the mouse jejunum in a schedule-dependent fashion. Our data tend to support the hypothesis that DNA synthesis inhibition and cell cycle redistribution are surrogates for radiosensitization. More data points are however required before a definite conclusion can be drawn

Relaxation equations for two-dimensional turbulent flows with a prior vorticity distribution

Using a Maximum Entropy Production Principle (MEPP), we derive a new type of relaxation equations for two-dimensional turbulent flows in the case where a prior vorticity distribution is prescribed instead of the Casimir constraints [Ellis, Haven, Turkington, Nonlin., 15, 239 (2002)]. The particular case of a Gaussian prior is specifically treated in connection to minimum enstrophy states and Fofonoff flows. These relaxation equations are compared with other relaxation equations proposed by Robert and Sommeria [Phys. Rev. Lett. 69, 2776 (1992)] and Chavanis [Physica D, 237, 1998 (2008)]. They can provide a small-scale parametrization of 2D turbulence or serve as numerical algorithms to compute maximum entropy states with appropriate constraints. We perform numerical simulations of these relaxation equations in order to illustrate geometry induced phase transitions in geophysical flows.Comment: 21 pages, 9 figure

Linear Protection Schemes Analysis in Scattered Placement Fiber-To-The Home-Passive Optical Network Using Customer Access Protection Unit Solution

<STRONG>Problem statement:</STRONG> This study highlights on restoration scheme proposed against failure in working line at the drop region for Fiber-To-The Home (FTTH) with a Passive Optical Network (PON). Whereas PON is a system that brings optical fiber cable and signals all or most of the way to the end user.<STRONG> Approach:</STRONG> Survivability scheme against failure is focused on scattered residence architectures and it is applied in the ring and tree topology respectively by means of Customer Access Protection Unit (CAPU). CAPU will be installed before the ONU and ensure the signal will find the alternative path when failure occurs at the specific line. Our proposal scheme is low cost and applicable to any residence architecture. The advantage of this scheme is the failure at fiber line can be recovered until three levels to make sure the optic signal flow continuously to avoid any application disturbance. Two type of restoration scheme is proposed by means of linear protection (tree) and migrated protection (ring). FTTH based network design is simulated by using Opti System 7.0 in order to investigate the power output and BER performance at each node in the tree and ring protection scheme in scattered placement. This study we perform an analysis on linear protection scheme that consisting of two model a) Line to Line (L2L) protection and CAPU to CAPU (C2C) or Shared protection. However the migration of tree to ring topology to enable the signal flow continuously in the case of failure occurs specifically in random or scattered placement topology has been highlighted in our previous publication. <STRONG>Results:</STRONG> The signal will be divided into section; drop and pass through and the ratio is significant to determine the number of user allowed and achievable distance. Output power for optical nodes could be slightly improved by varying the pass through and drop signal ratio. <STRONG>Conclusion:</STRONG> Our proposal is the first reported up to this time in which the upstream signal flows in anticlockwise in ring topology when the restoration scheme activated

The Minimal Supersymmetric Standard Model: Group Summary Report

CONTENTS: 1. Synopsis, 2. The MSSM Spectrum, 3. The Physical Parameters, 4. Higgs Boson Production and Decays, 5. SUSY Particle Production and Decays, 6. Experimental Bounds on SUSY Particle Masses, 7. References.Comment: 121 pages, latex + epsfig, graphicx, axodraw, Report of the MSSM working group for the Workshop "GDR-Supersym\'etrie",France. Rep. PM/98-4