4,864 research outputs found

    ENLIVE: An Efficient Nonlinear Method for Calibrationless and Robust Parallel Imaging

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    Robustness against data inconsistencies, imaging artifacts and acquisition speed are crucial factors limiting the possible range of applications for magnetic resonance imaging (MRI). Therefore, we report a novel calibrationless parallel imaging technique which simultaneously estimates coil profiles and image content in a relaxed forward model. Our method is robust against a wide class of data inconsistencies, minimizes imaging artifacts and is comparably fast combining important advantages of many conceptually different state-of-the-art parallel imaging approaches. Depending on the experimental setting, data can be undersampled well below the Nyquist limit. Here, even high acceleration factors yield excellent imaging results while being robust to noise and the occurrence of phase singularities in the image domain, as we show on different data. Moreover, our method successfully reconstructs acquisitions with insufficient field-of-view. We further compare our approach to ESPIRiT and SAKE using spin-echo and gradient echo MRI data from the human head and knee. In addition, we show its applicability to non-Cartesian imaging on radial FLASH cardiac MRI data. Using theoretical considerations, we show that ENLIVE can be related to a low-rank formulation of blind multi-channel deconvolution, explaining why it inherently promotes low-rank solutions.Comment: 17 pages, 10 figure

    Simultaneous Multi-Slice MRI using Cartesian and Radial FLASH and Regularized Nonlinear Inversion: SMS-NLINV

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    Purpose: The development of a calibrationless parallel imaging method for accelerated simultaneous multi-slice (SMS) MRI based on Regularized Nonlinear Inversion (NLINV), evaluated using Cartesian and radial FLASH. Theory and Methods: NLINV is a parallel imaging method that jointly estimates image content and coil sensitivities using a Newton-type method with regularization. Here, NLINV is extended to SMS-NLINV for reconstruction and separation of all simultaneously acquired slices. The performance of the extended method is evaluated for different sampling schemes using phantom and in-vivo experiments based on Cartesian and radial SMS-FLASH sequences. Results: The basic algorithm was validated in Cartesian experiments by comparison with ESPIRiT. For Cartesian and radial sampling, improved results are demonstrated compared to single-slice experiments, and it is further shown that sampling schemes using complementary samples outperform schemes with the same samples in each partition. Conclusion: The extension of the NLINV algorithm for SMS data was implemented and successfully demonstrated in combination with a Cartesian and radial SMS-FLASH sequence.Comment: Part of this work has been presented at the ISMRM Annual Conference 2016 (Singapore) and 2017 (Honolulu). 25 pages, 8+4 figure

    Transition from Poisson to gaussian unitary statistics: The two-point correlation function

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    We consider the Rosenzweig-Porter model of random matrix which interpolates between Poisson and gaussian unitary statistics and compute exactly the two-point correlation function. Asymptotic formulas for this function are given near the Poisson and gaussian limit.Comment: 19 pages, no figure

    Energy Loss of a High Charge Bunched Electron Beam in Plasma

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    There has been much interest in the blowout regime of plasma wakefield acceleration (PWFA), which features ultra-high fields and nonlinear plasma motion. Using an exact analysis, we examine here a fundamental limit of nonlinear PWFA excitation, by an infinitesimally short, relativistic electron beam. The beam energy loss in this case is shown to be linear in charge even for nonlinear plasma response, where a normalized, unitless charge exceeds unity. The physical basis for this effect is discussed, as are deviations from linear behavior observed in simulations with finite length beams.Comment: Submitted to Physical Review Letter

    Radiative Losses in Plasma Accelerators

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    We investigate the dynamics of a relativistic electron in a strongly nonlinear plasma wave in terms of classical mechanics by taking into account the action of the radiative reaction force. The two limiting cases are considered. In the first case where the energy of the accelerated electrons is low, the electron makes many betatron oscillations during the acceleration. In the second case where the energy of the accelerated electrons is high, the betatron oscillation period is longer than the electron residence time in the accelerating phase. We show that the force of radiative friction can severely limit the rate of electron acceleration in a plasma accelerator.Comment: 17 pages, 5 figure

    Semiclassical wave equation and exactness of the WKB method

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    The exactness of the semiclassical method for three-dimensional problems in quantum mechanics is analyzed. The wave equation appropriate in the quasiclassical region is derived. It is shown that application of the standard leading-order WKB quantization condition to this equation reproduces exact energy eigenvalues for all solvable spherically symmetric potentials.Comment: 13 page
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