1,156 research outputs found

    Effect of Gain-Dependent Phase Shift on Fiber Laser Synchronization

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    Recent experiments have demonstrated synchronization of fiber laser arrays at low and moderate pump levels. It has been suggested that a key dynamical process leading to synchronized behavior is the differential phase shift induced by the gain media. We explore theoretically the role of this effect in generating inphase dynamics. We find that its presence can substantially enhance the degree of inphase stability to an extent that could be practically important. At the same time, our analysis shows that a gain-dependent phase shift is not a necessary ingredient in the dynamical selection of the inphase state, thus, leading us to reconsider the essential mechanism behind inphase selection in fiber laser arrays

    Strong, Recent Selective Sweeps Reshape Genetic Diversity in Freshwater Bivalve \u3ci\u3eMegalonaias nervosa\u3c/i\u3e

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    Freshwater Unionid bivalves have recently faced ecological upheaval through pollution, barriers to dispersal, harvesting, and changes in fish–host prevalence. Currently, over 70% of species in North America are threatened, endangered or extinct. To characterize the genetic response to recent selective pressures, we collected population genetic data for one successful bivalve species, Megalonaias nervosa. We identify megabase-sized regions that are nearly monomorphic across the population, signals of strong, recent selection reshaping diversity across 73 Mb total. These signatures of selection are greater than is commonly seen in population genetic models. We observe 102 duplicate genes with high dN/dS on terminal branches among regions with sweeps, suggesting that gene duplication is a causative mechanism of recent adaptation in M. nervosa. Genes in sweeps reflect functional classes important for Unionid survival, including anticoagulation genes important for fish host parasitization, detox genes, mitochondria management, and shell formation. We identify sweeps in regions with no known functional impacts, suggesting mechanisms of adaptation that deserve greater attention in future work on species survival. In contrast, polymorphic transposable elements (TEs) appear to be detrimental and underrepresented among regions with sweeps. TE site frequency spectra are skewed toward singleton variants, and TEs among regions with sweeps are present at low frequency. Our work suggests that duplicate genes are an essential source of genetic novelty that has helped this species succeed in environments where others have struggled. These results suggest that gene duplications deserve greater attention in non-model population genomics, especially in species that have recently faced sudden environmental challenges

    Strong, recent selective sweeps reshape genetic diversity in freshwater bivalve Megalonaias nervosa

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    Freshwater Unionid bivalves have recently faced ecological upheaval through pollution, barriers to dispersal, human harvesting, and changes in fish-host prevalence. Currently, over 70% of species are threatened, endangered or extinct. To characterize the genetic response to these recent selective pressures, we collected population genetic data for one successful bivalve species, Megalonaias nervosa. We identify megabase sized regions that are nearly monomorphic across the population, a signal of strong, recent selection reshaping genetic diversity. These signatures of selection encompass a total of 73Mb, greater response to selection than is commonly seen in population genetic models. We observe 102 duplicate genes with high dN/dS on terminal branches among regions with sweeps, suggesting that gene duplication is a causative mechanism of recent adaptation in M. nervosa. Genes in sweeps reflect functional classes known to be important for Unionid survival, including anticoagulation genes important for fish host parasitization, detox genes, mitochondria management, and shell formation. We identify selective sweeps in regions with no known functional impacts, suggesting mechanisms of adaptation that deserve greater attention in future work on species survival. In contrast, polymorphic transposable element insertions appear to be detrimental and underrepresented among regions with sweeps. TE site frequency spectra are skewed toward singleton variants, and TEs among regions with sweeps are present only at low frequency. Our work suggests that duplicate genes are an essential source of genetic novelty that has helped this successful species succeed in environments where others have struggled. These results suggest that gene duplications deserve greater attention in non-model population genomics, especially in species that have recently faced sudden environmental challenges.Comment: 6 figures, 4 supplementary tables, 31 pages tota

    Old and New Fields on Super Riemann Surfaces

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    The ``new fields" or ``superconformal functions" on N=1N=1 super Riemann surfaces introduced recently by Rogers and Langer are shown to coincide with the Abelian differentials (plus constants), viewed as a subset of the functions on the associated N=2N=2 super Riemann surface. We confirm that, as originally defined, they do not form a super vector space.Comment: 9 pages, LaTex. Published version: minor changes for clarity, two new reference

    Feasibility Study of Compton Scattering Enchanced Multiple Pinhole Imager for Nuclear Medicine

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    This paper presents a feasibility study of a Compton scattering enhanced (CSE) multiple pinhole imaging system for gamma rays with energy of 140 keV or higher. This system consists of a multiple-pinhole collimator, a position sensitive scintillation detector as used in a standard gamma camera, and a Si pad detector array, inserted between the collimator and the scintillation detector. The problem of multiplexing, normally associated with multiple pinhole system, is reduced by using the extra information from the detected Compton scattering events. In order to compensate for the sensitivity loss, due to the low probability of detecting Compton scattered events, the proposed detector is designed to collect both Compton scattering and non-Compton events. It has been shown that with properly selected pinhole spacing, the proposed detector design leads to an improved image quality.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/86012/1/Fessler64.pd

    Vortices and the entrainment transition in the 2D Kuramoto model

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    We study synchronization in the two-dimensional lattice of coupled phase oscillators with random intrinsic frequencies. When the coupling KK is larger than a threshold KEK_E, there is a macroscopic cluster of frequency-synchronized oscillators. We explain why the macroscopic cluster disappears at KEK_E. We view the system in terms of vortices, since cluster boundaries are delineated by the motion of these topological defects. In the entrained phase (K>KEK>K_E), vortices move in fixed paths around clusters, while in the unentrained phase (K<KEK<K_E), vortices sometimes wander off. These deviant vortices are responsible for the disappearance of the macroscopic cluster. The regularity of vortex motion is determined by whether clusters behave as single effective oscillators. The unentrained phase is also characterized by time-dependent cluster structure and the presence of chaos. Thus, the entrainment transition is actually an order-chaos transition. We present an analytical argument for the scaling KEKLK_E\sim K_L for small lattices, where KLK_L is the threshold for phase-locking. By also deriving the scaling KLlogNK_L\sim\log N, we thus show that KElogNK_E\sim\log N for small NN, in agreement with numerics. In addition, we show how to use the linearized model to predict where vortices are generated.Comment: 11 pages, 8 figure

    Bias-Variance Tradeoffs Analysis Using Uniform CR Bound For a SPECT System

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    The authors quantify fundamental bias-variance tradeoffs for the image reconstruction problem in radio-pharmaceutical tomography using Cramer-Rao (CR) bound analysis. The image reconstruction problem is very often biased and the classical or the unbiased CR bound on the mean square error performance of the estimator can not be used. The authors use a recently developed “uniform” CR bound which applies to biased estimators whose bias gradient satisfies a user specified length constraint. The authors demonstrate the use of the “uniform” CR bound for a simple SPECT system using several different examples.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/85970/1/Fessler126.pd

    Universality in the one-dimensional chain of phase-coupled oscillators

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    We apply a recently developed renormalization group (RG) method to study synchronization in a one-dimensional chain of phase-coupled oscillators in the regime of weak randomness. The RG predicts how oscillators with randomly distributed frequencies and couplings form frequency-synchronized clusters. Although the RG was originally intended for strong randomness, i.e. for distributions with long tails, we find good agreement with numerical simulations even in the regime of weak randomness. We use the RG flow to derive how the correlation length scales with the width of the coupling distribution in the limit of large coupling. This leads to the identification of a universality class of distributions with the same critical exponent ν\nu. We also find universal scaling for small coupling. Finally, we show that the RG flow is characterized by a universal approach to the unsynchronized fixed point, which provides physical insight into low-frequency clusters.Comment: 14 pages, 10 figure

    Individual variability in preference for energy-dense foods fails to predict child BMI percentile

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    Many studies show that higher dietary energy density is associated with greater body weight. Here we explored two propositions: i) that child BMI percentile is associated with individual differences in children's relative preference for energy-dense foods, ii) that child BMI percentile is associated with the same individual differences between their parents. Child-parent dyads were recruited from a local interactive science center in Bristol (UK). Using computerized tasks, participants ranked their preference and rated their liking for a range of snack foods that varied in energy density. Children (aged 3–14 years, N = 110) and parents completed the tasks for themselves. Parents also completed two further tasks in which they ranked the foods in the order that they would prioritize for their child, and again, in the order that they thought their child would choose. Children preferred (t(109) = 3.91, p ≺ 0.001) and better liked the taste of (t(109) = 3.28, p = 0.001) higher energy-dense foods, and parents correctly estimated this outcome (t(109) = 7.18, p ≺ 0.001). Conversely, lower energy-dense foods were preferred (t(109) = − 4.63, p ≺ 0.001), better liked (t(109) = − 2.75, p = 0.007) and served (t(109) = − 15.06, p ≺ 0.001) by parents. However, we found no evidence that child BMI percentile was associated with child or parent preference for, or liking of, energy-dense foods. Therefore, we suggest that the observed relationship between dietary energy density and body weight is not explained by individual differences in preference for energy density

    Heritability of Clinical Mastitis Incidence and Relationships with Sire Transmitting Abilities for Somatic Cell Score, Udder Type Traits, Productive Life, and Protein Yield

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    The objective of this study was to determine the relationships among daughter clinical mastitis during first and second lactations and sire transmitting abilities for somatic cell score, udder type traits, productive life, and protein yield. Data on clinical mastitis during first lactation were available for 1795 daughters (in six Pennsylvania herds, one Minnesota herd, and one Nebraska herd) of 283 Holstein sires. Data on clinical mastitis during second lactation were available for 1055 of these daughters. A total of 479 cows had 864 clinical episodes during first lactation, and 230 cows had 384 clinical episodes during second lactation. Clinical mastitis incidence and the total number of clinical episodes during each lactation were regressed on herd-season of calving (a classification variable), age at first calving, lactation length, and sire transmitting abilities taken one at a time. Linear effects, nonlinear effects, and odds ratios were estimated for sire transmitting abilities. Separate analyses were conducted on dependent variables that considered clinical mastitis from: all organisms, coagulase-negative staphylococci, coliform species, streptococci other than Streptococcus agalactiae, and the most common environmental organisms (coliform species and streptococci other than Streptococcus agalactiae). Heritability of clinical mastitis ranged from 0.01 to 0.42. Daughters of sires that transmit the lowest somatic cell score had the lowest incidence of clinical mastitis and the fewest clinical episodes during first and second lactations. Daughters of sires that transmit longer productive life, shallower udders, deeper udder cleft, and strongly attached fore udders had either fewer clinical episodes or lower clinical mastitis incidence during first and second lactations. The incidence of clinical mastitis and the number of clinical episodes per lactation may be reduced by selection for lower somatic cell score, longer productive life, shallower udders, deeper udder cleft, or strongly attached fore udders
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