2,335 research outputs found
Polymeric foams as the matrix of voltammetric sensors for the detection of catechol, hydroquinone, and their mixtures
Producción CientíficaPorous electrodes based on polymethylmethacrylate and graphite foams (PMMA_G_F) have been developed and characterized. Such devices have been successfully used as voltammetric sensors to analyze catechol, hydroquinone, and their mixtures. The presence of pores induces important changes in the oxidation/reduction mechanism of catechol and hydroquinone with respect to the sensing properties observed in nonfoamed PMMA_graphite electrodes (PMMA_G). The electropolymerization processes of catechol or hydroquinone at the electrode surface observed using PMMA_G do not occur at the surface of the foamed PMM_G_F. In addition, the limits of detection observed in foamed electrodes are one order of magnitude lower than the observed in the nonfoamed electrodes. Moreover, foamed electrodes can be used to detect simultaneously both isomers and a remarkable increase in the electrocatalytic properties shown by the foamed samples, produces a decrease in the oxidation potential peak of catechol in presence of hydroquinone, from +0.7 V to +0.3 V. Peak currents increased linearly with concentration of catechol in presence of hydroquinone over the range of 0.37·10−3 M to 1.69·10−3 M with a limit of detection (LOD) of 0.27 mM. These effects demonstrate the advantages obtained by increasing the active surface by means of porous structures.Ministerio de Economía, Industria y Competitividad - Fondo Europeo de Desarrollo Regional (project AGL2015-67482-R)Junta de Castilla y Leon - Fondo Europeo de Desarrollo Regional (project VA-011U16
Control of magnetic domain wall motion in Co microwires by tridimensional e-beam lithographied structures
Resumen del póster presentado al 6th Spanish Workshop in Nanolithography celebrado en Zaragoza (España) del 28 al 30 de octubre de 2014.Work supported by the Spanish MICINN FIS2008-06249 and CSIC JAE Predoc grants.Peer Reviewe
Modelling driving behaviour and its impact on the energy management problem in hybrid electric vehicles
Perfect knowledge of future driving conditions can be rarely assumed on real applications when optimally splitting power demands among different energy sources in a hybrid electric vehicle. Since performance of a control strategy in terms of fuel economy and pollutant emissions is strongly affected by vehicle power requirements, accurate predictions of future driving conditions are needed. This paper proposes different methods to model driving patterns with a stochastic approach. All the addressed methods are based on the statistical analysis of previous driving patterns to predict future driving conditions, some of them employing standard vehicle sensors, while others require non-conventional sensors (for instance, global positioning system or inertial reference system). The different modelling techniques to estimate future driving conditions are evaluated with real driving data and optimal control methods, trading off model complexity with performance.Guardiola García, C.; Plá Moreno, B.; Blanco Rodriguez, D.; Reig Bernad, A. (2014). Modelling driving behaviour and its impact on the energy management problem in hybrid electric vehicles. International Journal of Computer Mathematics. 91(1):147-156. doi:10.1080/00207160.2013.829567S147156911Ericsson, E. (2001). Independent driving pattern factors and their influence on fuel-use and exhaust emission factors. Transportation Research Part D: Transport and Environment, 6(5), 325-345. doi:10.1016/s1361-9209(01)00003-7Q. Gong, P. Tulpule, V. Marano, S. Midlam-Mohler, and G. Rizzoni,The role of ITS in PHEV performance improvement, 2011 American Control Conference, June–July, San Francisco, CA, 2011, pp. 2119–2124.C. Guardiola, B. Pla, S. Onori, and G. Rizzoni,A new approach to optimally tune the control strategy for hybrid vehicles applications, IFAC Workshop on Engine and Powertrain Control, Simulation and Modeling E-COSM’12, October, Rueil-Malmaison, France, 2012.Johannesson, L., Asbogard, M., & Egardt, B. (2007). Assessing the Potential of Predictive Control for Hybrid Vehicle Powertrains Using Stochastic Dynamic Programming. IEEE Transactions on Intelligent Transportation Systems, 8(1), 71-83. doi:10.1109/tits.2006.884887Liu, S., & Yao, B. (2008). Coordinate Control of Energy Saving Programmable Valves. IEEE Transactions on Control Systems Technology, 16(1), 34-45. doi:10.1109/tcst.2007.903073Paganelli, G. (2001). General supervisory control policy for the energy optimization of charge-sustaining hybrid electric vehicles. JSAE Review, 22(4), 511-518. doi:10.1016/s0389-4304(01)00138-2Rizzoni, G., Guzzella, L., & Baumann, B. M. (1999). Unified modeling of hybrid electric vehicle drivetrains. IEEE/ASME Transactions on Mechatronics, 4(3), 246-257. doi:10.1109/3516.789683Control of hybrid electric vehicles. (2007). IEEE Control Systems, 27(2), 60-70. doi:10.1109/mcs.2007.338280L. Serrao, S. Onori, and G. Rizzoni,ECMS as realization of Pontryagin's minimum principle for HEV control, 2009 American Control Conference, June, Saint Louis, MO, 2009, pp. 3964–3969.Serrao, L., Onori, S., & Rizzoni, G. (2011). A Comparative Analysis of Energy Management Strategies for Hybrid Electric Vehicles. Journal of Dynamic Systems, Measurement, and Control, 133(3). doi:10.1115/1.4003267Stockar, S., Marano, V., Canova, M., Rizzoni, G., & Guzzella, L. (2011). Energy-Optimal Control of Plug-in Hybrid Electric Vehicles for Real-World Driving Cycles. IEEE Transactions on Vehicular Technology, 60(7), 2949-2962. doi:10.1109/tvt.2011.2158565Sundström, O., Ambühl, D., & Guzzella, L. (2009). On Implementation of Dynamic Programming for Optimal Control Problems with Final State Constraints. Oil & Gas Science and Technology – Revue de l’Institut Français du Pétrole, 65(1), 91-102. doi:10.2516/ogst/2009020O. Sundström and L. Guzzella,A generic dynamic programming Matlab function, 18th IEEE International Conference on Control Applications Part of 2009 IEEE Multi-conference on Systems and Control, July, Saint Petersburg, 2009, pp. 1625–1630.R. Wang and S.M. Lukic,Review of driving conditions prediction and driving style recognition based control algorithms for hybrid electric vehicles, Vehicle Power and Propulsion Conference (VPPC), 2011 IEEE, September 6–9, Raleigh, NC, 2011, pp. 1–7
The Role of IL-33 in Host Response to Candida albicans
Background. Interleukin (IL) 33 is a recently identified pleiotropic cytokine that influences the activity of multiple cell types and orchestrates complex innate and adaptive immune responses. Methods. We performed an extensive review of the literature published between 2005 and 2013 on IL-33 and related cytokines, their functions, and their regulation of the immune system following Candida albicans colonization. Our literature review included cross-references from retrieved articles and specific data from our own studies. Results. IL-33 (IL-1F11) is a recently identified member of the IL-1 family of cytokines. Accumulating evidence suggests a pivotal role of the IL-33/ST2 axis in host immune defense against fungal pathogens, including C. albicans. IL-33 induces a Th2-type inflammatory response and activates both innate and adaptive immunity. Studies in animal models have shown that Th2 inflammatory responses have a beneficial role in immunity against gastrointestinal and systemic infections by Candida spp. Conclusions. This review summarizes the most important clinical studies and case reports describing the beneficial role of IL-33 in immunity and host defense mechanisms against pathogenic fungi. The finding that the IL-33/ST2 axis is involved in therapeutic target has implications for the prevention and treatment of inflammatory diseases, including acute or chronic candidiasis
Effects of ketosis on cocaine-induced reinstatement in male mice;
In recent years, the benefits of the ketogenic diet (KD) on different psychiatric disorders have been gaining attention, but the substance abuse field is still unexplored. Some studies have reported that palatable food can modulate the rewarding effects of cocaine, but the negative metabolic consequences rule out the recommendation of using it as a complementary treatment. Thus, the main aim of this study was to evaluate the effects of the KD on cocaine conditioned place preference (CPP) during acquisition, extinction, and reinstatement. 41 OF1 male mice were employed to assess the effects of the KD on a 10 mg/kg cocaine-induced CPP. Animals were divided into three groups: SD, KD, and KD after the Post-Conditioning test. The results revealed that, while access to the KD did not block CPP acquisition, it did significantly reduce the number of sessions required to extinguish the drug-associated memories and it blocked the priming-induced reinstatement. © 2022 The Author(s
Aproximación ontosemiótica de prácticas de aula sobre la medida en educación primaria
En este trabajo se presenta un estudio exploratorio sobre prácticas de aula, relacionadas con las magnitudes longitud, tiempo y masa, llevadas a cabo en Educación Primaria en Portugal. El estudio fijó como objetivos determinar qué objetos y procesos matemáticos están implicados en esas prácticas y qué funciones ejecutan profesor y alumnos durante la realización de las mismas. Los resultados han evidenciado el predominio del conocimiento procedimental y algorítmico y el uso de situaciones extramatemáticas o de la vida cotidiana. El profesor es el gestor sistemático del trabajo de los alumnos así como de los tiempos, espacios y materiales disponibles en el aula
Un SIG corporativo en el IGN para la gestión integrada, publicación y análisis de datos geográficos
El Instituto Geográfico Nacional inició en el año 2003 los estudios previos necesarios para un proyecto ambicioso y a la vez esencial para el cumplimiento de sus responsabilidades básicas, la implantación de un Sistema de Información Geográfica (SIG) corporativo que atendiera a tres finalidades fundamentales: a) la gestión integrada de los datos geográficos y cartográficos que produce, en forma de Bases Cartográficas Numéricas (BCN) y en forma de mapas, respectivamente, incluyendo su actualización coordinada; b) la publicación de tales datos en papel, en soporte digital y de manera electrónica (Infraestructura de Datos Espaciales (IDE)); c) el análisis y consulta desde clientes ligeros y pesados para todo tipo de aplicaciones. Por lo tanto, el sistema constituye a la vez el soporte básico para la publicación de cartografía y para la consulta de los datos geográficos desde clientes a través de la Web,mediante el desarrollo de servicios de análisis
Habilidades del psicólogo en drogodependencias
Las habilidades del terapeuta constituyen un aspecto fundamental para la consecución de los distintos objetivos que al psicólogo se le plantean en el transcurso de su intervención con el usuario drogodependiente. En este articulo se presenta una revisión de las habilidades que los autores consideran imprescindibles, aportando ejemplos prácticos y con independencia de la orientación teórica del psicólogo. Las habilidades técnicas o profesionales se refieren a conocimientos teóricos y prácticos; el afltocontrol emocional, incluyendo tanto el afrontamiento ef caz por parte del psicólogo de ciertas situaciones ante el usuario, y especificamente si éste es un drogodelincuente, como el afrontamiento del burn out; y por último, las habilidades sociales, en las que se sustenta la interacción entre el psicólogo y el usuario, destacando la asertividad y la empatia. Finalmente se revisan distintos aspectos y principios generales referidos a la ética profesional en la práctica de la Psicologia Clínica
Distribution of Tetracycline Resistance Genes in Actinobacillus pleuropneumoniae Isolates from Spain
P. 702-708Actinobacillus pleuropneumoniae is the etiological agent of porcine pleuropneumonia. Tetracycline is used for
therapy of this disease, and A. pleuropneumoniae carrying the tet(B) gene, coding for an efflux protein that
reduces the intercellular tetracycline level, has been described previously. Of the 46 tetracycline-resistant (Tcr)
Spanish A. pleuropneumoniae isolates used in this study, 32 (70%) carried the tet(B) gene, and 30 of these genes
were associated with plasmids. Eight (17%) isolates carried the tet(O) gene, two (4%) isolates carried either the
tet(H) or the tet(L) gene, and all these genes were associated with plasmids. This is the first description of these
tet genes in A. pleuropneumoniae. The last two Tcr isolates carried none of the tet genes examined. Except
for tet(O)-containing plasmids, the other 34 Tcr plasmids were transformable into an Escherichia coli recipient.
Two plasmids were completely sequenced. Plasmid p11745, carrying the tet(B) gene, was 5,486 bp and included
a rep gene, encoding a replication-related protein, and two open reading frames (ORFs) with homology to
mobilization genes of Neisseria gonorrhoeae plasmid pSJ7.4. Plasmid p9555, carrying the tet(L) gene, was 5,672
bp and, based on its G C content, consisted of two regions, one of putative gram-positive origin containing the
tet(L) gene and the other comprising four ORFs organized in an operon-like structure with homology to
mobilization genes in other plasmids of gram-negative bacteriaS
Effects of dry needling on gait and muscle tone in Parkinson''s disease: a randomized clinical trial
Background: Alterations in gait and muscular rigidity are common and disabling in persons with Parkinson''s disease (PD). Objective: The aim of this study was to determine whether a single dry needling (DN) session can promote changes in gait and muscle tone in the lower extremities as well as in the evolution of the disease in persons with PD. Methods: A randomized double-blind clinical trial was designed. Participants were randomly assigned to an intervention group (IG) that received a session of DN over the semitendinosus, medial gastrocnemius, soleus and rectus femoris muscles, or to a control group (CG) that received a session of sham DN in the same muscles. The effects of DN were assessed using the timed up and go test (TUG), 10 meter walk test (10MWT), 6 minute walk test (6MWT) and myotonometry before, immediately after, and 7 days after the intervention. Results: Thirty-three participants were analyzed aged 69.9 +/- 7.2 years (mean +/- SD; 39% female). There were no significant differences between the IG and CG for any outcomes. Significant differences were observed when comparing the Pre and Follow-up values in the IG for functional mobility of gait in the TUG (p = 0.049), gait speed in the 10MWT (p = 0.041) and muscle tone in the lower extremities by myotonometry (frequency (p = 0.027) and stiffness (p = 0.013)). By comparison, there were no significant within-group differences in the CG. Conclusion: A single session of DN had no measurable benefit compared to a single session of sham DN. Within-group changes in the IG suggested improvements in functional mobility of gait and gait speed, as well as changes in the muscle tone in the lower extremities of PD patients, which could be worthy of further exploration by future research
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