Diseño de espacios y materiales para el aprendizaje autónomo: intervención en los rincones de trabajo

El espacio constituye un agente educativo de primer orden, con capacidad por sí mismo para estimular todo tipo de aprendizajes, respetando y atendiendo a los distintos ritmos, necesidades e intereses existentes en un aula de Educación Infantil y favoreciendo la autonomía del niño, que pasa a ser un sujeto activo de su propio aprendizaje. Este Trabajo Fin de Grado presenta una propuesta de intervención que incluye el diseño y la construcción de ocho materiales didácticos para su introducción en un aula real, en la que se sigue una metodología de trabajo por rincones durante parte de la jornada escolar. Dicha intervención ha puesto de manifiesto la capacidad y el interés innato de los niños por investigar, crear y manipular, aprendiendo de forma lúdica y placentera cuando se ponen a su disposición los medios necesarios para ello. Además, se pone en valor una alternativa profesional para educadores como es la autoconstrucción de materiales para su utilización en el aula, comprobando su verdadero valor educativo en relación al autoaprendizaje.Universidad de Sevilla. Grado en Educación Infanti

Animal models of pediatric chronic kidney disease. Is adenine intake an appropriate model?

AbstractPediatric chronic kidney disease (CKD) has peculiar features. In particular, growth impairment is a major clinical manifestation of CKD that debuts in pediatric age because it presents in a large proportion of infants and children with CKD and has a profound impact on the self-esteem and social integration of the stunted patients. Several factors associated with CKD may lead to growth retardation by interfering with the normal physiology of growth plate, the organ where longitudinal growth rate takes place. The study of growth plate is hardly possible in humans and justifies the use of animal models. Young rats made uremic by 5/6 nephrectomy have been widely used as a model to investigate growth retardation in CKD. This article examines the characteristics of this model and analyzes the utilization of CKD induced by high adenine diet as an alternative research protocol

Psychometric properties of the flourishing scale in a sample of Spanish emerging adults

Flourishing is a recent conceptualization standing for people’s general well-being. It refers to the perception experienced by anyone whose life is going on well. It is a combination of feeling well and working with efficiency (Huppert & So, 2013; Huppert, 2009a; Huppert, 2009b; Keyes, 2002; Ryff & Singer, 1998). An individual who “flourishes” notices his or her life is going on well, learns things with efficiency and works productively. There is a higher possibility he or she would contribute to his or her community. He or she is healthier, has a longer life expectancy, as well as better social relationships (Diener, 2009; Huppert, 2010). Flourishing is synonymous of having a high level of mental well-being; moreover, it accounts for mental health and positive development. The flourishing scale (FS) (Diener et al., 2010), binds the essential components of recent welfare theories together. It is an adequate measure of general well-being. In fact, its major advantages compared with previously existing measures are its briefness and reasonable comprehension, which makes the scale easier to use solitarily or together with other tools. The FS, which is composed by eight items, has good psychometric properties. The purpose of this study was to evaluate the psychometric properties of the Spanish version of the FS. Spanish university students whose socio-cultural backgrounds differ are the subjects of the research. They come from Euskadi and Andalusia, two regions within Spain. Method The sample was composed by 1502 university students. This number was achieved through collecting two samples, one from the University of Basque Country (65.2% females, average age = 19.95, SD age = 1.97, age range 18-29, N = 747) and the other, from the University of Seville (55.1% females; average age = 20.69, SD age = 2.21, age range 18-29, N = 755). The participants agreed to voluntarily participate in the test session and fulfill the following questionnaires: Socio-demographic Questionnaire; Flourishing Scale (Diener et al., 2010), the Spanish version of the Ryff’s Scale of Psychological Well-Being, SPWB (Díaz et al., 2006) and the Spanish version of the Depression Anxiety Stress Scales: DASS-21 (Bados, Solanas & Andrés, 2005 ). Results The reliability analysis and Multigroup Confirmatory Factorial Analysis (MCFA) revealed that the Flourishing Scale shows strong internal consistency. The one-factor structure was invariant across the two samples, according to the results from the original version of the Flourishing Scale (Diener et al. 2010) and other later validations. Results also demonstrated convergent and discriminant validity with PWBS and DASS scales. Discussion According to the results of the study, FS could be appropriate for its use in assessing general wellbeing among emerging adults in Spain. It may be recognised as an alternative instrument in the evaluation of the positive mental health, as well as a complementary tool to estimate young adults’s general health. FS may as well be recognised as a potential tool for prevention and community involvement in the future

Flourishing during emerging adulthood from a gender perspective

Flourishing is when an individual perceives that their life is going smoothly. It encompasses hedonic and eudaimonic aspects of well-being: feeling good and functioning well. The construct’s correlation with indicators of adjustment and positive development makes it an attractive concept for assessing well-being. Emerging adulthood is a transitional period susceptible to numerous changes that can impact on flourishing. Using a gender-based approach in a sample of 1502 Spanish university students aged between 18 and 29 years, we examined the characteristics of emerging adults most associated with their flourishing. The study included perceived family income, variables related to developmental tasks inherent in this stage, variables that define the period, educational variables and social support variables. A clear distinction between male and female flourishing and its correlates was observed. Flourishing in females was significantly higher than in males. The study variables explained 46% of flourishing in male respondents and 16% in female respondents; the predictors of flourishing differed by gender. These gender differences are discussed, and the recommendation is made for future research to include other variables that successfully explain female flourishing and which shed light on the identified gender gap.Ministerio de Economía y Competitividad de España EDU2013-45687-RMinisterio de Ciencia, Innovación y Universidades de España RTI2018-097405-B-I0

Flourishing and social relationships during emerging adulthood in Spain

Archivo descargado de web de Inmaculada Sánchez-Queija http://personal.us.es/queija/index.php?page=actas-y-congresosPsychosocial flourishing is a recent conceptualization of social and psychological well being. Flourishing is a combination of feeling good and working effectively. The person who “flourishes” notices that her/his life is going well, works productively, contribute to the community, is healthier, has a longer life expectancy, and has better social relationships. Social relationships, and particularly perceived friends and family support, as well as romantic relationships, play an important role as predictor of positive development in emerging adulthood. In this way, these social relationships contribute to wellbeing and flourishing in this stage of development. Emerging Adulthood is a period of instability and exploration in which young people will probably have more distanced relationships with their parents than in previous years, and couples will burst into important figures for development. For this reason, it´s necessary to study the influence of family, peer and romantic relationships over the young people positive development. The main goal of this paper is to know if social relationships among emerging adults, in particular, the perceived social support from parents and friends and the quality of romantic relationship, have an effect on the psychological flourishing of a sample of Spanish emerging adults. Method The sample was composed by 278 young adults (197 female), aged range 18 to 29 years. They completed a self-administered questionnaire which included flourishing (Flourishing scale; Diener et al., 2010), family and peer support (Multidimensional Scale of Perceived Social Support; Zimet et al., 1988) and romantic relationship (Experience of Close Relationship; ECRR, short; Wei et al., 2007). Results Results showed that flourishing of young adults is positively related to the perceived social support of family and friends, and negatively related to the anxiety in romantic relationships. Flourishing was related to sex: women reached higher levels of flourishing than men. Nevertheless, the regression equations revealed that, once included family support, anxiety in romantic relationships and friends support, sex ceased being influential. Thus we may conclude that during emerging adulthood flourishing is closely linked to the social network, in particular, to the family, romantic and friends relationships, in that order. Discussion These first results point out the significance of social relationships for flourishing in emerging adulthood. It is especially important the family role. Family influence remains essential for these years, contributing to flourishing more than peer support and romantic relationships. However, more research with larger samples is necessary to explain the factors determining flourishing during the emerging adulthood in diverse cultural contexts.Ministerio de Economía y Competitividad de España EDU2013-45687-

Role of the rs10401670 variant in the resistin gene on the metabolic response after weight loss secondary to a high‐fat hypocaloric diet with a Mediterranean pattern

Producción CientíficaBackground:The single nucleotide polymorphism (SNP) (rs10401670) of theRETNgene has been associated with metabolic disorder in obese subjects andhas scarcely been evaluated after dietary interventions. The present studyaimed to analyse the effects of thers10401670 RETNgene polymorphismon metabolic changes secondary to weight loss and secondary to a high‐fathypocaloric diet with a Mediterranean dietary pattern.Methods:A Caucasian population comprising 284 obese patients withoutdiabetes mellitus was analysed. Before and after 3 months of a high‐fathypocaloric diet with a Mediterranean pattern, an anthropometric evaluation,an assessment of nutritional intake and a biochemical analysis were per-formed. A statistical analysis was conducted for the combinedCTandTTas agroup and for wild‐typeCCas a second group.Results:Decreases in weight, body mass index (BMI), fat mass, systolic bloodpressure and waist circumference were similar in both genotypes groups. InTallele carriers, insulin, homeostatic model assessment for insulin resistance(HOMA‐IR), triglycerides and C‐reactive protein levels were decreased.The decrease in these parameters was statistically significant for triglycerides(−22.3 ± 9.3 mg dl–1:p= 0.03), C‐reactive protein (−2.8 ± 0.5 mg dl–1:p= 0.03), insulin (−7.4 ± 2.9 mUI L–1:p= 0.03) and HOMA‐IR (−2.4 ± 1.0:p= 0.02). Leptin levels were decreased in both genotypes groups after thehypocaloric diet, as well as the anthropometric parameters BMI, weight, waistcircumference and fat mass. Resistin and adiponectin levels remained un-changed in both groups.Conclusions:In the present study, we have detected a significant associationbetween theTallele of this SNP and a better response of insulin resistance,triglycerides and C‐reactive protein compared to nonTallele carriers afterweight loss with a high‐fat hypocaloric diet and a Mediterranean diet

A longitudinal view of flourishing and family relations during emerging adulthood in Spain

Flourishing is when an individual perceives that their life is going smoothly. It encompasses the hedonic and eudaimonic aspects of well-being: feeling good and functioning well (Huppert & So, 2013; Keyes & Annas, 2009). The correlation of the construct with indicators of adjustment and positive development makes it an attractive concept to assess well-being (Huta & Ryan, 2010; Keyes, 2007; Keyes et al., 2012). Emerging adulthood is a developmental stage that has arisen in western countries as a result of social and economic changes in recent decades. It describes a period that begins in late adolescence and lasts well into the third decade of life (Arnett, 2000). Studies focused on this stage, considered crucial in the determination of people's health and well-being pathways (Chen et al., 2019), have found an association between the adjustment of emerging adults and positive family relationships. It seems that family continues to have a major influence on young people's development (Fingerman & Yahirun, 2016) during emerging adulthood as well. Specifically, positive family relationships are associated with high levels of psychological well-being during the third decade of life (Zupančič et al, 2014). The main objective of this study is to examine the association between flourishing and family variables during emerging adulthood from a gender perspective and using longitudinal analysis. Therefore, this work has two specific goals: first, to examine the stability of the flourishing of emerging adults throughout the initial years (Wave 1) and intermediate years (Wave 2) of emerging adulthood, and second, to analyze whether family relationships were associated with the flourishing of emerging adults. A longitudinal study was carried out at two time points: wave 1 (Mean: 20.31; SD: 2.04) and (three years later) wave 2 (Mean: 23.66; SD: 2.08). The sample comprised 400 emerging adults (268 women) from the Transition to Adulthood in Spain research project (TAE) who completed a questionnaire assessing their perceptions of the quality of their family relationships (parental social support, parental involvement, parental warmth, parental autonomy support, and behavioral and psychological control) and their level of flourishing. The results show the stability of the flourishing between W1 and W2. They also show a statistically significant relationship between flourishing and family variables and interesting gender differences. The crucial role that family also has during emerging adulthood is highly reflected in the results

Selective Oxidative Dearomatization of Angular Tetracyclic Phenols by Controlled Irradiation under Air: Synthesis of an Angucyclinone-Type Double Peroxide with Anticancer Properties

Angular tetracyclic p-peroxyquinols, p-quinols and a pentacyclic double peroxide, showing anticancer properties, were Selective oxidative dearomatization of angular tetracyclic phenols by controlled irradiation under air: synthesis of an angucyclinone‐type double peroxide with anticancer properties María J. Cabrera-Afonso,a Silvia R. Lucena,b Ángeles Juarranz,b Antonio Urbano,*a,c M. Carmen Carreño*a,c aDepartamento de Química Orgánica, Universidad Autónoma de Madrid (UAM), Cantoblanco, 28049-Madrid, Spain. bDepartamento de Biología, UAM, Cantoblanco, 28049-Madrid, Spain. cInstitute for Advanced Research in Chemical Sciences (IAdChem), UAM, Cantoblanco, 28049-Madrid, Spain. Supporting Information Placeholder synthesized from the corresponding phenols by an environmentally friendly solvent- and wavelength-controlled irradiation under air in the absence of an external photosensitizerWe thank MINECO (Grants CTQ2017-83309-P, CTQ2014-53894R and FIS PI15/00974) for financial suppor

Relation of resistin levels with cardiovascular risk factors, insulin resistance and inflammation in naı¨ve diabetes obese patients

Producción CientíficaBackground: The aim of the present study was to explore the relationship of resistin levels with cardiovascular risk factors, insulin resistance and inflammation in naı¨ve diabetic patients. Subjects: A population of 66 naı¨ve diabetic patients with obesity was analyzed. A complete nutritional and biochemical evaluation was performed. Results: The mean age 56.9 11.6 years and the mean BMI was 37.8 6.3. Patients were divided in two groups by median resistin value (3.3 ng/ml), group I (patients with the low values, average value 2.5 0.5) and group II (patients with the high values, average value 4.8 1.8). Patients in the group I had lower waist circumference, total cholesterol, LDLcholesterol and C-reactive protein than patients in group II. Correlation analysis showed a significant correlation among resistin levels and the independent variables; BMI (r = 0.26; p < 0.05), waist circumference (r = 0.38; p < 0.05), fat mass (r = 0.28; p < 0.05), LDL-cholesterol (r = 0.3; p < 0.05), C-reactive protein (r = 0.28; p < 0.05). In the multivariate analysis, resistin concentration increase 0.024 ng/ml (CI 95%: 0.006–0.42) for each mg/dl of C-reactive protein. Conclusion: Circulating resistins are associated with C-reactive protein in an independent way in naı¨ve diabetic patients

Género y espacio público: nueve ensayos

I. PERFILES: CAPÍTULO 1. Rocío Orsi Portalo (Universidad Carlos III de Madrid): Vírgenes y mártires. Dos escenarios premodernos.- CAPÍTULO 2. Cinta Canterla (Universidad Pablo de Olavide): La filosofía y la ciencia en el s. XVIII, a propósito de la biopolítica y la categorización de lo público y lo privado.- CAPÍTULO 3. Carmen González Marín (Universidad Carlos III de Madrid): La ansiedad de la diferencia.- CAPÍTULO 4. Laura Calvo Valdivieso (Editorial Impedimenta): Mujeres renacentistas en la “res publica litterarum”.- CAPÍTULO 5. María Jesús Fuente (Universidad Autónoma de Madrid): Cruzando el umbral. Mujeres en el proceso de paso del espacio privado al público -- II. HACIA LA CONTEMPORANEIDAD: CAPÍTULO 6. Laura Branciforte (Universidad Carlos III de Madrid): El “singular” recorrido de las mujeres en los espacios públicos contemporáneos.- CAPÍTULO 7. Montserrat Huguet Santos (Universidad Carlos III de Madrid): Espacios de papel: vidas domésticas y escrituras burguesas.- CAPÍTULO 8. Leticia Naranjo Gálvez (Universidad del Rosario): Opresión y representación de lo femenino. Apuntes sobre la capacidad de agencia y la fortuna moral.- CAPÍTULO 9. Rocío Navarro (Universidad Carlos III de Madrid): Mujeres españolas en el siglo XX: asociacionismo y activismo político (Estado de la cuestión