156 research outputs found

    Romanticism’s Fellow Creatures

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    This panel opens up innovative ways of thinking about Romanticism and “the problem of sharing our earth with other creatures.” Over the last couple of decades, the crisis in human relations with animals has deteriorated to the point that it has become increasingly recognized as a constitutive part of the global environmental crisis. Like the climate crisis, the “animal crisis” originates with the emergence of the industrial form of capitalism in Britain around the turn of the nineteenth century. Appreciation of this historical constellation can and should become the basis of a renewed Romantic animal studies. However, reading Romanticism as a reflection of and on the historical origins of the contemporary crisis in human-animal relations in turn requires rethinking and openly debating topics, archive, and method. To indicate the initial results and style of our efforts, we have chosen not to summarize the papers presented, but rather to pose ten collectively formulated questions and to briefly answer as individuals a selection of three of those questions. Overall, we hope not just to make an argument for what we regard as a vital area of research in Romantic studies, but to encourage more research on the topic

    A VACCINE PROTOTYPE USING BACULOVIRUS EXPRESSION SYSTEM FOR THE CONTROL OF AVIAN INFLUENZA VIRUS

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    A clade 1 sequence of H5 haemaglutinin from an Asian Avian H5N1 isolate was used as a the template to chemically synthetize a codon optimized version for expression in insect cells. A single clone was chosen for expression optimization and changes were introduced in order to maximize the amount of protein to be produced and to resemble another sequence demonstrated to be present in an isolate causing disease in Humans. Preliminary analysis at lab scale have shown promising yields of the haemaglutinin using an activity titration assay and an ELISA-based detection method. Optimization of the cell seeding, MOI, and time of harvest have provided valuable data to ensure sufficient production of the protein compatible with scale up application. In order to test the biological activity of the expressed protein and its ability to trigger an immune response, oil/water emulsions of different amounts of the protein were administered to SPF chickens and antibodies levels were detected using an ELISA-based system and HI titration. Both approaches were able to demonstrate seroconvertion and a dose-response curve was observed among the different doses. Altogether, results support the feasibility of the genetic contruct and the expression platform to produce bulk amounts of protein which could be used for different purposes

    La movilidad transfronteriza venezolana en la producción académica: ¿quiénes y qué dice la ciencia?

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    This article presents the main research findings on scientific production on Venezuelan migration between 2014 and 2021. Using the bibliometric analysis method to observe the global state of science on Venezuelan cross-border mobility, the research measured scientific production with quantitative indicators and analyzed its content with qualitative indicators to identify the main thematic tendencies on what was investigated in a wide set of disciplinary fields. Finally, it discusses the qualitative results showing the gaps and challenges involved in consolidating the lines of research on Venezuelan migration.El presente artículo expone los principales hallazgos de investigación sobre la producción científica acerca de la migración venezolana entre los años 2014 y 2021. Usando el método de análisis bibliométrico para observar el estado de la ciencia a nivel global sobre la movilidad transfronteriza venezolana, la investigación midió la producción científica con indicadores cuantitativos y analizó su contenido con indicadores cualitativos para identificar las principales tendencias temáticas sobre lo investigado en un amplio conjunto de ámbitos disciplinares. Finalmente, discute los resultados cualitativos mostrando los vacíos y retos que supone la consolidación de las líneas de investigación sobre la movilidad transfronteriza venezolana

    La ambigüedad de la justicia transnacional. El caso interamericano de los derechos humano

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    Inter-American human rights justice is a phenomenon of transnational influence on the legal systems of national states. The growing interaction of the Inter-American Court with national judges and its work as interpreter of the American Convention on Human Rights (IACHR) has fostered excessive optimism that needs to be critically reviewed for the sake of a better understanding of transnational. To fulfill this task, this document will present the doctrinal discussions on justice, validity, and effectiveness of the IACHR through the scope, limits, and impact of the Inter-American judicial exercise.La justicia interamericana de derechos humanos es un fenómeno de transnacional influencia sobre los ordenamientos jurídicos de los Estados nacionales. La creciente interacción de la Corte Interamericana con los jueces nacionales y su labor como intérprete de la Convención Americana de Derechos Humanos (CADH) ha promovido un excesivo optimismo que resulta necesario revisar críticamente en aras de una mejor comprensión de la justicia transnacional en derechos humanos. Para cumplir este cometido, el presente documento presentará las discusiones doctrinales sobre justicia, validez y eficacia de la CADH a través del alcance, límites e impacto del ejercicio judicial Interamericano

    AFRICA BUILD Portal: developing a social network of African health researchers and educators

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    One of the main outputs of the project is a collaborative platform which integrates a myriad of research and learning resources. This article presents the first prototype of this platform: the AFRICA BUILD Portal (ABP 1.0). The ABP is a Web 2.0 platform which facilitates the access, in a collaborative manner, to these resources. Through a usable web interface, the ABP has been designed to avoid, as much as possible, the connectivity problems of African institutions. In this paper, we suggest that the access to complex systems does not imply slow response rates, and that their development model guides the project to a natural technological transfer, adaptation and user acceptance. Finally, this platform aims to motivate research attitudes during the learning process and stimulate user?s collaborations

    Bose-Einstein condensate dark matter phase transition from finite temperature symmetry breaking of Klein-Gordon fields

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    In this paper the thermal evolution of scalar field dark matter particles at finite cosmological temperatures is studied. Starting with a real scalar field in a thermal bath and using the one loop quantum corrections potential, we rewrite Klein-Gordon's (KG) equation in its hydrodynamical representation and study the phase transition of this scalar field due to a Z_2 symmetry breaking of its potential. A very general version of a nonlinear Schr\"odinger equation is obtained. When introducing Madelung's representation, the continuity and momentum equations for a non-ideal SFDM fluid are formulated, and the cosmological scenario with the SFDM described in analogy to an imperfect fluid is then considered where dissipative contributions are obtained in a natural way.Additional terms appear compared to those obtained in the classical version commonly used to describe the \LambdaCDM model, i.e., the ideal fluid. The equations and parameters that characterize the physical properties of the system such as its energy, momentum and viscous flow are related to the temperature of the system, scale factor, Hubble's expansion parameter and the matter energy density. Finally, some details on how galaxy halos and smaller structures might be able to form by condensation of this SF are given.Comment: Substantial changes have been made to the paper, following the referees recommendations. 16 pages. Published in Classical and Quantum Gravit

    Estiércol solarizado y dos métodos de riego en la producción de chile jalapeño (Capsicum annuum L. var. annuum)

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    Increase of water use efficiency in crops through better irrigation systems and use of farmyard manure to fertilize plants and avoid contamination are needs in arid regions. The objective was to evaluate a jalapeño pepper crop with organic fertilization and two irrigation methods.This research was carried out at Gomez Palacio, Durango, Mexico, in 2013 and 2014. The experimental units were randomly distributed in a split plot design with four replications. Main plots were irrigation treatments and fertilizers were applied as split plot treatments within each irrigation treatment. Irrigation was applied with either a furrow irrigation system to apply 80% of the measured pan evaporation or drip irrigation set to deliver 60% of the measured evaporation. The drip irrigation treatment showed greater fruit yield than the surface irrigation (p<0.05). Green fruit yield was similar among fertilized treatments in 2013 (p>0.05) and different in 2014 (p<0.05) with 40 t ha-1 solarized manure having the greatest fruit yield. Soil organic matter and nitrate-N content were greatest in 2013 when solarized manure 40 t ha-1 was used. There were no differences among fertilizer treatments in 2014 (p>0.05). Soil pH and electrical conductivity remained unchanged among treatments in each year of the study. Drip irrigation had a positive effect in the fruit yield in spite of delivering a lesser amount of water. The solarized manure applied at 40 t ha-1 had the greater effect in the fruit yield in year 2 but not in year 1.Incrementar el uso eficiente del agua a través de mejores sistemas de irrigación y el uso de estiércol de vaca para fertilizar plantas y evitar la contaminación son necesidades en regiones áridas. El objetivo fue evaluar un cultivo de chile jalapeño con fertilización orgánica y dos métodos de irrigación. La investigación fue llevada a cabo en Gómez Palacio, Durango, México en 2013 y 2014. Las unidades experimentales fueron distribuidas aleatoriamente en un diseño de parcelas divididas con cuatro repeticiones. Las parcelas grandes fueron los tratamientos de irrigación y los tratamientos de fertilización fueron las subparcelas. El agua aplicada a través de surcos de irrigación fue el 80% de evaporación medida en un tanque evaporímetro o bien a través del riego por goteo para aplicar 60% del agua evaporada. El tratamiento de riego por goteo mostró mayor cosecha de fruto que el riego por surcos (p<0,05). La cosecha de fruto fue igual entre los tratamientos de fertilización en 2013 (p>0,05) y diferente en 2014 (p<0,05) con el tratamiento de 40 t ha-1 de estiércol solarizado teniendo la mayor producción de fruto. La materia orgánica del suelo y el contenido de nitratos fueron mayores en 2013 en el tratamiento 40 t ha-1 de estiércol solarizado. No hubo diferencias entre tratamientos de fertilización en 2014. El pH del suelo y la conductividad eléctrica no tuvieron cambios entre tratamientos en los dos años de estudio. El riego por goteo tuvo un efecto positivo en la producción de fruto a pesar de que se aplicó menos cantidad de agua. El estiércol solarizado aplicado a 40 t ha-1 tuvo el mayor efecto en el año 2 pero no en el año 1.Fil: Maraña-Santacruz, José Ángel. Universidad Juárez del Estado de Durango (México). Facultad de Agronomía y Zootecnia.Fil: Castellanos-Pérez, Edmundo. Universidad Juárez del Estado de Durango (México). Facultad de Agronomía y Zootecnia.Fil: Vázquez-Vázquez, Cirilo. Universidad Juárez del Estado de Durango (México). Facultad de Agronomía y Zootecnia.Fil: Martínez-Ríos, Juan José. Universidad Juárez del Estado de Durango (México). Facultad de Agronomía y Zootecnia.Fil: Trejo-Escareño, Héctor Idilio. Universidad Juárez del Estado de Durango (México). Facultad de Agronomía y Zootecnia.Fil: Gallegos-Robles, Miguel Ángel. Universidad Juárez del Estado de Durango (México). Facultad de Agronomía y Zootecnia

    Fabrication and characterisation of poly(sulfonated) and poly(sulfonic acid) dissolving microneedles for delivery of antibiotic and antifungal agents

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    Skin and soft tissue infections (SSTIs) arise from microbial ingress into the skin. In this study, poly(2-acrylamido-2-methyl-1-propanesulfonic acid) (polyAMPS), which has been reported to exhibit antimicrobial properties was synthesised for the manufacture of microarray patches (MAPs). The free acid and sodium salt of polyAMPS with controlled molar masses and narrow dispersity were synthesised via reversible addition − fragmentation chain-transfer (RAFT) polymerisation reaction with a monomer conversion of over 99%, as determined by 1H NMR. The polymers were shown to be biocompatible when evaluated using a fibroblast dermal cell line while agar plating assay using cultures of C. albican demonstrated that the acid form of polyAMPS exhibited antimicrobial inhibition, which is potentiated in the presence of antimicrobial agents. The synthesised polymers were then used to fabricate dissolving MAPs, which were loaded with either ITRA or levofloxacin (LEV). The MAPs displayed acceptable mechanical resistance and punctured ex vivo skin to a depth of 600 µm. Skin deposition studies revealed that the MAPs were able to administer up to ∼ 1.9 mg of LEV (delivery efficiency: 94.7%) and ∼ 0.2 mg of ITRA (delivery efficiency: 45.9%), respectively. Collectively, the synthesis and development of this novel pharmaceutical system may offer a strategy to manage SSTIs.<br/
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