A history of the Episcopal Church in Omaha from 1856 to 1964

There are three reasons for writing a history of the Episcopal Church in Omaha with an emphasis on the foundation years. This period covers the years 1856 to 1960. First, there is a desire for a complete understanding of the history of Omaha and the various institutions that helped to make the city. Second, there is a request to have a greater understanding of the development and growth of the State of Nebraska. And thirdly, there never has been a history of the activities of the Episcopal Church in Omaha

Cognitive performance in multiple system atrophy

The cognitive performance of a group of patients with multiple system atrophy (MSA) of striato-nigral predominance was compared with that of age and IQ matched control subjects, using three tests sensitive to frontal lobe dysfunction and a battery sensitive to memory and learning deficits in Parkinson's disease and dementia of the Alzheimer type. The MSA group showed significant deficits in all three of the tests previously shown to be sensitive to frontal lobe dysfunction. Thus, a significant proportion of patients from the MSA group failed an attentional set-shifting test, specifically at the stage when an extra-dimensional shift was required. They were also impaired in a subject-ordered test of spatial working memory. The MSA group showed deficits mostly confined to measures of speed of thinking, rather than accuracy, on the Tower of London task. These deficits were seen in the absence of consistent impairments in language or visual perception. Moreover, the MSA group showed no significant deficits in tests of spatial and pattern recognition previously shown to be sensitive to patients early in the course of probable Alzheimer's disease and only a few patients exhibited impairment on the Warrington Recognition Memory Test. There were impairments on other tests of visual memory and learning relative to matched controls, but these could not easily be related to fundamental deficits of memory or learning. Thus, on a matching-to-sample task the patients were impaired at simultaneous but not delayed matching to sample, whereas difficulties in a pattern-location learning task were more evident at its initial, easier stages. The MSA group showed no consistent evidence of intellectual deterioration as assessed from their performance on subtests of the Wechsler Adult Intelligence Scale (WAIS) and the National Adult Reading Test (NART). Consideration of individual cases showed that there was some heterogeneity in the pattern of deficits in the MSA group, with one patient showing no impairment, even in the face of considerable physical disability. The results show a distinctive pattern of cognitive deficits, unlike those previously seen using the same tests in patients with Parkinson's and Alzheimer's diseases, and suggesting a prominent frontal-lobe-like component. The implications for concepts of 'subcortical' dementia and 'fronto-striatal' cognitive dysfunction are considered

Characterization of the C. elegans erlin homologue

<p>Abstract</p> <p>Background</p> <p>Erlins are highly conserved proteins associated with lipid rafts within the endoplasmic reticulum (ER). Biochemical studies in mammalian cell lines have shown that erlins are required for ER associated protein degradation (ERAD) of activated inositol-1,4,5-trisphosphate receptors (IP3Rs), implying that erlin proteins might negatively regulate IP3R signalling. In humans, loss of erlin function appears to cause progressive intellectual disability, motor dysfunction and joint contractures. However, it is unknown if defects in IP3R ERAD are the underlying cause of this disease phenotype, whether ERAD of activated IP3Rs is the only function of erlin proteins, and what role ERAD plays in regulating IP3R-dependent processes in the context of an intact animal or embryo. In this study, we characterize the erlin homologue of the nematode <it>Caenorhabditis elegans </it>and examine erlin function <it>in vivo</it>. We specifically set out to test whether <it>C. elegans </it>erlin modulates IP3R-dependent processes, such as egg laying, embryonic development and defecation rates. We also explore the possibility that erlin might play a more general role in the ERAD pathway of <it>C. elegans</it>.</p> <p>Results</p> <p>We first show that the <it>C. elegans </it>erlin homologue, ERL-1, is highly similar to mammalian erlins with respect to amino acid sequence, domain structure, biochemical properties and subcellular location. ERL-1 is present throughout the <it>C. elegans </it>embryo; in adult worms, ERL-1 appears restricted to the germline. The expression pattern of ERL-1 thus only partially overlaps with that of ITR-1, eliminating the possibility of ERL-1 being a ubiquitous and necessary regulator of ITR-1. We show that loss of ERL-1 does not affect overall phenotype, or alter brood size, embryonic development or defecation cycle length in either wild type or sensitized <it>itr-1 </it>mutant animals. Moreover we show that ERL-1 deficient worms respond normally to ER stress conditions, suggesting that ERL-1 is not an essential component of the general ERAD pathway.</p> <p>Conclusions</p> <p>Although loss of erlin function apparently causes a strong phenotype in humans, no such effect is seen in <it>C. elegans</it>. <it>C. elegans </it>erlin does not appear to be a ubiquitous major modulator of IP3 receptor activity nor does erlin appear to play a major role in ERAD.</p

Fronto-striatal cognitive deficits at different stages of Parkinson's disease

Groups of patients with idiopathic Parkinson's disease, either medicated or unmedicated, were compared with matched groups of normal controls on a computerized battery previously shown to be sensitive to frontal lobe dysfunction, including tests of planning, spatial working memory and attentional set-shifting. In a series of problems based on the 'Tower of London' test, medicated patients with Parkinson's disease were shown to be impaired in the amount of time spent thinking about (planning) the solution to each problem. Additionally, an impairment in terms of the accuracy of the solution produced on this test was only evident in those patients with more severe clinical symptoms and was accompanied by deficits in an associated test of spatial short-term memory. Medicated patients with both mild and severe clinical symptoms were also impaired on a related test of spatial working memory. In contrast, a group of patients who were unmedicated and 'early in the course' of the disease were unimpaired in all three of these tests. However, all three Parkinson's disease groups were impaired in the test of attentional set-shifting ability, although unimpaired in a test of pattern recognition which is insensitive to frontal lobe damage. These data are compared with those previously published from a group of young neurosurgical patients with localized excisions of the frontal lobes and are discussed in terms of the specific nature of the cognitive deficit at different stages of Parkinson's disease

Influence of spacing and crown recession on wood quality of intensively-managed young-growth Douglas-fir

Intensive management of young-growth Douglas-fir plantations has emphasized volume growth over wood quality. A better understanding of the variables that affect wood quality is needed so that wood quality and stand yield can be systematically combined into a silviculture program. This experiment utilized two separate experiments to establish the relationship bebtwen wood quality, stand density, and artificial pruning. The influence of initial stand density on branch diameter, wood density, and tracheid length was explored utilizing 56 trees, 19 and 21 years old, at two sites in central western Oregon. Trees were sampled from Nelder plots ranging in density from 309 trees/ha to 18,730 trees/ha. The effects of fixed-height pruning on wood density and tracheid length were investigated using trees 23, 26, and 28 years old, after ten years of growth following pruning. Mean branch diameter, maximum branch diameter, number of branches/m, longevity of radial branch growth, and longevity of terminal branch growth all increased with decreasing initial tree density. After accounting for initial tree density, 1:2 rectangularity of spacing did not affect indicators of wood quality relative to 1:1 rectangularity of spacing. When age was held constant, there was no evidence that either wood density or tracheid length at breast height varied with initial tree density or crown characteristics. In contrast, there was evidence that ring density, earlywood density, and percent latewood increased linearly with initial tree density at the 5.27 m sampling height. There was no significant change in growth rate or wood density at breast height (1.37 m) or 5.27 m as a result of pruning 15% or less of the live crown length. In contrast, pruning to 5.5 m at age 13 resulted in a one-year decrease in earlywood width and an increase in percent latewood at 1.37 m. At the 5.27 m sampling height, there was a temporary increase in earlywood density, percent latewood, and mean ring density. Pruning at age 13 to 3.4 m and 5.5 m resulted in an increase in mean, earlywood, and latewood tracheid length of approximately 6% for three years. Wide initial spacing, combined with pruning appears to be the best choice for improving wood quality of Douglas-fir. Even though juvenile wood volume will be greater due to wide spacing, the increase in log diameter and clear wood volume will enhance log grade, especially if pruning occurs early in the rotation and is combined with commercial thinning to promote diameter growth

Evaluating LAANC Utilization & Compliance for Small Unmanned Aircraft Systems in Controlled Airspace

On July 23, 2019, the Federal Aviation Administration (FAA) expanded the Low Altitude Authorization and Notification Capability (LAANC)—the system that processes airspace approvals for sUAS operators in controlled airspace—to include recreational operations. Researchers sought to collect and evaluate 30 days of UAS operational activity in controlled airspace using UAS detection equipment. Detected UAS flight data was compared against UAS Facility Maps and LAANC approval data to assess UAS operator compliance and behavior patterns. Researchers documented 94 LAANC approvals and detected 271 UAS flights within the sample area during the sampling period. The research team noted that UAS detections exceeded LAANC authorizations by a rate of approximately four-to-one. Only 7.0% of detected UAS operations could be correlated to a LAANC authorization, possibly indicating significant rates of non-compliance. Additionally, researchers determined that 34.3% (n =93) of detected UAS operations exceeded maximum altitudes prescribed for their respective location. Forty-four percent (n =41) of UASFM altitude exceedances occurred above 500 feet AGL, posing potential risk to manned aviation operations in the National Airspace System. Researchers advocate for the implementation of additional measures to curtail non-compliance, including additional UAS operator training, deterrence, and enforcement measures. The research team intends to expand this study to additional airports via related research projects within the FAA’s ASSURE Program

A pictorial key to differentiate the recently detected exotic Haemaphysalis longicornis Neumann, 1901 (Acari, Ixodidae) from native congeners in North America

Until recently, only two haemaphysaline species, Haemaphysalis chordeilis (Packard, 1869) and Haemaphysalisleporispalustris (Packard, 1869), were known to occur in the United States, and neither was consideredto be of significant medical or veterinary importance. In 2017?2018 established populations ofthe Asian longhorned tick, Haemaphysalis longicornis Neumann, 1901, were detected in the eastern US forthe first time. Haemaphysalis longicornis has the potential to be a significant threat to human and animalhealth, and the urgent need to determine the full extent of its distribution and host range requires availabilityof a straightforward and practical guide to differentiate it from native species. We created a pictorialdichotomous key to all stages of Haemaphysalis spp. known to occur in North America with scanningelectron photomicrographs of all H. longicornis life stages, including rarely seen males, to aid researchers indifferentiating these species. The largely Neotropical species Haemaphysalis juxtakochi Cooley, 1946, withestablished populations in Mexico and sporadic detections in the US on migrating birds is also included.Fil: Egizi, Andrea M.. Monmounth County Mosquito Control Division; Estados UnidosFil: Robbins, Richard G.. Smithsonian Institution; Estados UnidosFil: Beati, Lorenza. Georgia Southern University;Fil: Nava, Santiago. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Santa Fe. Estación Experimental Agropecuaria Rafaela; ArgentinaFil: Evans, Colleen R.. Georgia Southern University;Fil: Occi, James L.. Georgia Southern University;Fil: Fonseca, Dina M.. Georgia Southern University

Evaluating LAANC Compliance and Air Traffic Collision Hazards Posed by Small Unmanned Aircraft Operations in Controlled Airspace

On July 23, 2019, the Federal Aviation Administration (FAA) expanded the Low Altitude Authorization and Notification Capability (LAANC)—the system that processes airspace approvals for sUAS operators in controlled airspace—to include recreational operations. Under LAANC, sUAS operators submit flight request information to one of 14 LAANC Service Suppliers via a mobile or online application. Flight request data is checked against UAS Facility Maps, NOTAMs, and Temporary Flight Restrictions to ensure compliance. Small UAS operators then receive a digital, automated authorization in near-real time. As of May 23, 2019, 591 airports across the United States are included in the LAANC system. Researchers sought to collect and evaluate sUAS operational activity in controlled airspace using UAS detection equipment. Detected sUAS flight data was compared against airspace information, temporary flight restrictions, UAS Facility Maps, and LAANC approval data to assess sUAS operator compliance and behavior patterns. Small UAS detections and LAANC authorization data was further compared against air traffic data to identify potential UAS flight interference and collision hazards with air traffic