17,034 research outputs found

    Effects of microgravity on rat muscle

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    It is well known that humans exposed to long term spaceflight experience undesirable progressive muscle weakness and increased fatigability. This problem has prompted the implementation of inflight exercise programs because most investigators believe that the major cause of diminished muscle performance is a combination of disuse and decreased workload. Inflight exercise has improved muscle health, but deficits have persisted, indicating that either the regimens utilized were suboptimal or there existed additional debilitating factors which were not remedied by exercise. Clarification of this question requires an improved understanding of the cellular and molecular basis of spaceflight-induced muscle deterioration. To this end, multiple investigations have been performed on the muscles from rats orbited 5 to 22 days in Cosmos biosatellites and Spacelab-3 (2,4,5,8,10 to 14,16,18,19,21 to 23,25,27,28). The eight Cosmos 1887 investigations examined the structural and biochemical changes in skeletal and cardiac muscles of rats exposed to microgravity for 12.5 days and returned to terrestrial gravity 2.3 days before tissues were collected. Even though interpretation of these results was complicated by the combination of inflight and postflight induced alterations, the consensus is that there is marked heterogeneity in both degree and type of responses from the whole muscle level down to the molecular level. Collectively, the muscle investigations of Cosmos 1887 clearly illustrate the wide diversity of muscle tissue responses to spaceflight. Judging from the summary report of this mission, heterogeneity of responses is not unique to muscle tissue. Elucidating the mechanism underlying this heterogeneity holds the key to explaining adaptation of the organism to prolonged spaceflight

    A Ka-band (32 GHz) beacon link experiment (KABLE) with Mars Observer

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    A proposal for a Ka-Band (32 GHz) Link Experiment (KABLE) with the Mars Observer mission was submitted to NASA. The experiment will rely on the fourth harmonic of the spacecraft X-band transmitter to generate a 33.6 GHz signal. The experiment will rely also on the Deep Space Network (DSN) receiving station equipped to simultaneously receive X- and Ka-band signals. The experiment will accurately measure the spacecraft-to-Earth telecommunication link performance at Ka-band and X-band (8.4 GHz)

    Redundant Arrays of IDE Drives

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    The next generation of high-energy physics experiments is expected to gather prodigious amounts of data. New methods must be developed to handle this data and make analysis at universities possible. We examine some techniques that use recent developments in commodity hardware. We test redundant arrays of integrated drive electronics (IDE) disk drives for use in offline high-energy physics data analysis. IDE redundant array of inexpensive disks (RAID) prices now equal the cost per terabyte of million-dollar tape robots! The arrays can be scaled to sizes affordable to institutions without robots and used when fast random access at low cost is important. We also explore three methods of moving data between sites; internet transfers, hot pluggable IDE disks in FireWire cases, and writable digital video disks (DVD-R).Comment: Submitted to IEEE Transactions On Nuclear Science, for the 2001 IEEE Nuclear Science Symposium and Medical Imaging Conference, 8 pages, 1 figure, uses IEEEtran.cls. Revised March 19, 2002 and published August 200

    Second Epoch Global VLBI Observations of Compact Radio Sources in the M82 Starburst Galaxy

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    We have presented the results of a second epoch of global Very Long Baseline Interferometry observations, taken on 23 February 2001 at a wavelength of 18 cm, of the central kiloparsec of the nearby starburst galaxy Messier 82. These observations were aimed at studying the structural and flux evolution of some of the compact radio sources in the central region that have been identified as supernova remnants. The objects 41.95+575 and 43.31+592 have been studied, expansion velocities of 2500 +/- 1200 km/s and 7350 +/- 2100 km/s respectively have been derived. Flux densities of 31.1 +/- 0.3 mJy and 17.4 +/- 0.3 mJy have been measured for the two objects. These results are consistent with measurements and predictions from previous epochs.Comment: 5 pages, 3 figures. To be published on the accompanying CD of the Proceedings of IAU Colloquium 192: Supernova

    KASR: A Reliable and Practical Approach to Attack Surface Reduction of Commodity OS Kernels

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    Commodity OS kernels have broad attack surfaces due to the large code base and the numerous features such as device drivers. For a real-world use case (e.g., an Apache Server), many kernel services are unused and only a small amount of kernel code is used. Within the used code, a certain part is invoked only at runtime while the rest are executed at startup and/or shutdown phases in the kernel's lifetime run. In this paper, we propose a reliable and practical system, named KASR, which transparently reduces attack surfaces of commodity OS kernels at runtime without requiring their source code. The KASR system, residing in a trusted hypervisor, achieves the attack surface reduction through a two-step approach: (1) reliably depriving unused code of executable permissions, and (2) transparently segmenting used code and selectively activating them. We implement a prototype of KASR on Xen-4.8.2 hypervisor and evaluate its security effectiveness on Linux kernel-4.4.0-87-generic. Our evaluation shows that KASR reduces the kernel attack surface by 64% and trims off 40% of CVE vulnerabilities. Besides, KASR successfully detects and blocks all 6 real-world kernel rootkits. We measure its performance overhead with three benchmark tools (i.e., SPECINT, httperf and bonnie++). The experimental results indicate that KASR imposes less than 1% performance overhead (compared to an unmodified Xen hypervisor) on all the benchmarks.Comment: The work has been accepted at the 21st International Symposium on Research in Attacks, Intrusions, and Defenses 201

    Reducing CR-BSI in a general ICU

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    Ka-band MMIC beam steered transmitter array

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    A 32-GHz six-element linear transmitter array utilizing monolithic microwave integrated circuit (MMIC) phase shifters and power amplifiers was designed and tested as part of the development of a spacecraft array feed for NASA deep-space communications applications. Measurements of the performance of individual phase shifters, power amplifiers, and microstrip radiators were carried out, and electronic beam steering of the linear array was demonstrated. The switched-line phase shifters were accurate to within 7 percent on average and the power amplifier 1-dB compressed output power varied over 0.3 dB. The array had a beamwidth of 7.5 deg and demonstrated acceptable beam steering over + or - 8 deg. From the results, it can be concluded that this MMIC phased array has adequate beam-scanning capability for use in the two-dimensional array. The areas that need to be improved are the efficiency of the MMIC power amplifier and the insertion loss of the MMIC phase shifter
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