O brincar na educação física infantil: uma revisão sistemática / Playing in children's physical education: a systematic review

O artigo tem por objetivo desenvolver uma revisão sistemática acerca dos artigos publicados, nas principais revistas nacionais da área da Educação Física, que tenham como foco o brincar na Educação Física Infantil e identificar o número de artigos nas diferentes revistas, as metodologias mais utilizadas, os autores mais citados e verificar os principais resultados alcançados nesses artigos.  A seleção dos artigos para a pesquisa se deu por meio de busca eletrônica no Portal Periódicos CAPES/MEC, por este reunir inúmeros artigos de revistas cientificas especializadas para acesso de pesquisadores em todo Brasil.  A busca foi feita com as seguintes palavras chaves: Brincar, Educação Física Infantil e Educação Infantil. Observou-se nos 11 artigos selecionados para a análise, por estarem relacionados ao brincar na educação física infantil, a grande importância que o brincar tem no processo de ensino e aprendizagem de crianças, mas que ainda não é incentivado da forma que deveria ser nas escolas. Muitas vezes, os objetivos de aceleração da alfabetização negligenciam e sufocam o brincar no espaço escolar. Os artigos ainda enfatizam a necessidade de mais estudos sobre o brincar e sua relação com o processo de ensino e aprendizagem

Em torno da mesa do rei: artefatos, convivialidade e celebração no Rio de Janeiro joanino

Este artigo aborda um aspecto relevante do ritual das refeições na corte de D. João VI, no Rio de Janeiro: a prataria de mesa. Isto é, objetos de luxo destinados a servir e a consumir os alimentos. Com base em um inventário de bens de mesa enviados do Rio de Janeiro para Lisboa junto com o monarca em seu retorno a Portugal, em 1821, este artigo procura refletir sobre as funções e possíveis usos desses objetos, assim como sobre a importância desse universo material para o funcionamento, representação e celebração da Casa Real portuguesa na sua nova sede. O artigo argumenta que a presença e o uso de baixelas de prata de serviço, mas também de grande aparato, nas refeições públicas da família real pode contribuir para se repensar a imagem de uma corte pobre e sem brilho recorrentemente reforçada na historiografia do período joanino.This article discusses a specific issue of the royal dinner's rituals at the Court of Rio de Janeiro: the silver service: some luxury artifacts of different forms specially made to serve and consume food. Based on a inventory of these silver objects and also on a stock of table linen which were shipped to Lisbon, along with the royal family in 1821, The article intend to explore the functions and utilities of those objects at the table, as well as, analyze the importance of this material universe for the functioning, representation and celebration of the Portuguese Royal House in its new headquarters.The article argues that the use and even the exhibition of the banquet silver in public ceremonies may contribute to change a rather depreciative image of poverty the royal court in Brazil, which has being explored by the historiography for more than a hundred years

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19

IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022). INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days. MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes. RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively). CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570

Effects of various pre-analytical conditions on blood-based biomarkers of Alzheimer's disease.

peer reviewe

Les élémens de chymie / de M. Iean Beguin, ... reveuz, notez, expliquez, & augmentez, par J. L. D.R. B. IC. E. M. ; En ceste derniere edition ont esté adioustées plusieurs explications obmises aux precedentes impressions, & plusieurs preparations de remedes tirés de la derniere edition latine

ÍndexMarca tip. xil. dels impressors a port.Capll. orn.Sign.: â8, A-Z8, Aa-Dd8L'abreviatura de l'editor literari es correspon a: Jean Lucas de Roy, baccal. juris c. et med

Long-term effects of Passive Integrated Transponder Tagging (PIT-Tag) on the growth of the yellow European eel (Anguilla anguilla)

Passive Integrated Transponder tags (PIT tags) are recommended as the most suitable method for tagging fish on the basis of their high retention and fish survival rates. The objective of this study was to determine the long-term effects (between 1 and 11 years) of the PIT tag on the growth of the yellow European eel (Anguilla anguilla). A difference of more than 50% was observed in the growth of marked and unmarked yellow eels. If this is a general long term effect in all eels, it would seriously restrict the use of PIT tags for studying the dynamics of European eel populations, and so for their management