77 research outputs found
A laserball calibration device for the SNO+ scintillator phase
Located 2 km underground in SNOLAB, Sudbury, Canada, SNO+ is a large scale
liquid scintillator experiment that primarily aims to search for neutrinoless
double beta decay. Whilst SNO+ has light and radioactive calibration sources
external to the inner volume, an internally deployed optical source is
necessary for the full characterization of the detector model. A laser diffuser
ball developed for SNO has previously demonstrated to be an effective optical
calibration device for both SNO and SNO+ water phase. Since the introduction of
liquid scintillator for SNO+, the material compatibility, cleanliness, and
radiopurity requirements of any materials in contact with the internal medium
have increased. Improving on the original SNO laserball design, a new laserball
calibration device has been developed for the SNO+ scintillator phase with the
goal of measuring the optical properties of the detector and performing routine
PMT gain and timing calibrations. Simulations have been written to model the
diffusion properties to optimise optical and temporal performance for
calibration. Prototype laserballs have been built and characterised,
demonstrating sub-ns timing resolution and a quasi-isotropic light distributionComment: 21 pages, 16 figure
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Improved search for invisible modes of nucleon decay in water with the SNO + detector
This paper reports results from a search for single and multinucleon disappearance from the O16 nucleus in water within the SNO+ detector using all of the available data. These so-called "invisible"decays do not directly deposit energy within the detector but are instead detected through their subsequent nuclear deexcitation and gamma-ray emission. New limits are given for the partial lifetimes: Ļ(nāinv)>9.0Ć1029 years, Ļ(pāinv)>9.6Ć1029 years, Ļ(nnāinv)>1.5Ć1028 years, Ļ(npāinv)>6.0Ć1028 years, and Ļ(ppāinv)>1.1Ć1029 years at 90% Bayesian credibility level (with a prior uniform in rate). All but the (nnāinv) results improve on existing limits by a factor of about 3
Clinical impact of genomic testing in patients with suspected monogenic kidney disease
Purpose:
To determine the diagnostic yield and clinical impact of exome sequencing (ES) in patients with suspected monogenic kidney disease.
Methods:
We performed clinically accredited singleton ES in a prospectively ascertained cohort of 204 patients assessed in multidisciplinary renal genetics clinics at four tertiary hospitals in Melbourne, Australia.
Results:
ES identified a molecular diagnosis in 80 (39%) patients, encompassing 35 distinct genetic disorders. Younger age at presentation was independently associated with an ES diagnosis (pā<ā0.001). Of those diagnosed, 31/80 (39%) had a change in their clinical diagnosis. ES diagnosis was considered to have contributed to management in 47/80 (59%), including negating the need for diagnostic renal biopsy in 10/80 (13%), changing surveillance in 35/80 (44%), and changing the treatment plan in 16/80 (20%). In cases with no change to management in the proband, the ES result had implications for the management of family members in 26/33 (79%). Cascade testing was subsequently offered to 40/80 families (50%).
Conclusion:
In this pragmatic pediatric and adult cohort with suspected monogenic kidney disease, ES had high diagnostic and clinical utility. Our findings, including predictors of positive diagnosis, can be used to guide clinical practice and health service design
Measurement of neutron-proton capture in the SNO+ water phase
The SNO+ experiment collected data as a low-threshold water Cherenkov
detector from September 2017 to July 2019. Measurements of the 2.2-MeV
produced by neutron capture on hydrogen have been made using an Am-Be
calibration source, for which a large fraction of emitted neutrons are produced
simultaneously with a 4.4-MeV . Analysis of the delayed coincidence
between the 4.4-MeV and the 2.2-MeV capture revealed a
neutron detection efficiency that is centered around 50% and varies at the
level of 1% across the inner region of the detector, which to our knowledge is
the highest efficiency achieved among pure water Cherenkov detectors. In
addition, the neutron capture time constant was measured and converted to a
thermal neutron-proton capture cross section of mb
Measurement of the 8B solar neutrino flux in SNO+ with very low backgrounds
A measurement of the 8B solar neutrino flux has been made using a 69.2 kt-day dataset acquired with the SNO+ detector during its water commissioning phase. At energies above 6 MeV the dataset is an extremely pure sample of solar neutrino elastic scattering events, owing primarily to the detectorās deep location, allowing an accurate measurement with relatively little exposure. In that energy region the best fit background rate is 0.25+0.09ā0.07āāevents/ktāday, significantly lower than the measured solar neutrino event rate in that energy range, which is 1.03+0.13ā0.12āāevents/ktāday. Also using data below this threshold, down to 5 MeV, fits of the solar neutrino event direction yielded an observed flux of 2.53+0.31ā0.28(stat)+0.13ā0.10(syst)Ć106āācmā2āsā1, assuming no neutrino oscillations. This rate is consistent with matter enhanced neutrino oscillations and measurements from other experiments
Event-by-Event Direction Reconstruction of Solar Neutrinos in a High Light-Yield Liquid Scintillator
The direction of individual B solar neutrinos has been reconstructed
using the SNO+ liquid scintillator detector. Prompt, directional Cherenkov
light was separated from the slower, isotropic scintillation light using time
information, and a maximum likelihood method was used to reconstruct the
direction of individual scattered electrons. A clear directional signal was
observed, correlated with the solar angle. The observation was aided by a
period of low primary fluor concentration that resulted in a slower
scintillator decay time. This is the first time that event-by-event direction
reconstruction in high light-yield liquid scintillator has been demonstrated in
a large-scale detector.Comment: 6 pages, 6 figures. Accepted manuscript by PR
Improved search for invisible modes of nucleon decay in water with the SNO+ detector
This paper reports results from a search for single and multi-nucleon
disappearance from the O nucleus in water within the \snoplus{} detector
using all of the available data. These so-called "invisible" decays do not
directly deposit energy within the detector but are instead detected through
their subsequent nuclear de-excitation and gamma-ray emission. New limits are
given for the partial lifetimes:
years, years, years,
years, and years at 90\% Bayesian
credibility level (with a prior uniform in rate). All but the () results improve on existing limits by a factor of about 3.info:eu-repo/semantics/publishedVersio
Observation of Antineutrinos from Distant Reactors using Pure Water at SNO+
The SNO+ collaboration reports the first observation of reactor antineutrinos
in a Cherenkov detector. The nearest nuclear reactors are located 240 km away
in Ontario, Canada. This analysis used events with energies lower than in any
previous analysis with a large water Cherenkov detector. Two analytical methods
were used to distinguish reactor antineutrinos from background events in 190
days of data and yielded consistent observations of antineutrinos with a
combined significance of 3.5 .Comment: v2: add missing author, add link to supplemental materia
Doping liquid argon with xenon in ProtoDUNE Single-Phase: effects on scintillation light
Doping of liquid argon TPCs (LArTPCs) with a small concentration of xenon is a technique for light-shifting and facilitates the detection of the liquid argon scintillation light. In this paper, we present the results of the first doping test ever performed in a kiloton-scale LArTPC. From February to May 2020, we carried out this special run in the single-phase DUNE Far Detector prototype (ProtoDUNE-SP) at CERN, featuring 720 t of total liquid argon mass with 410 t of fiducial mass. A 5.4 ppm nitrogen contamination was present during the xenon doping campaign. The goal of the run was to measure the light and charge response of the detector to the addition of xenon, up to a concentration of 18.8 ppm. The main purpose was to test the possibility for reduction of non- uniformities in light collection, caused by deployment of photon detectors only within the anode planes. Light collection was analysed as a function of the xenon concentration, by using the pre-existing photon detection system (PDS) of ProtoDUNE-SP and an additional smaller set-up installed specifically for this run. In this paper we first summarize our current understanding of the argon-xenon energy transfer process and the impact of the presence of nitrogen in argon with and without xenon dopant. We then describe the key elements of ProtoDUNE-SP and the injection method deployed. Two dedicated photon detectors were able to collect the light produced by xenon and the total light. The ratio of these components was measured to be about 0.65 as 18.8 ppm of xenon were injected. We performed studies of the collection efficiency as a function of the distance between tracks and light detectors, demonstrating enhanced uniformity of response for the anode-mounted PDS. We also show that xenon doping can substantially recover light losses due to contamination of the liquid argon by nitrogen
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