Teaching Psychological Principles to Cybersecurity Students

This paper will discuss our observations gained from teaching psychological principles and methods to undergraduate and postgraduate cybersecurity students. We will draw on and extend our previous work encouraging the teaching of psychology in computing and cybersecurity education. We pay special attention to the consideration of characteristics of cybersecurity students in terms of teaching psychology in a way that will be accessible and engaging. We then discuss the development and use of an online training tool which draws on psychology to help educators and companies to raise awareness of cybersecurity risks in students and employees. Finally, we offer some practical suggestions to incorporate psychology into the cybersecurity curriculum

Grafius and Anderson

It is widely assumed that, among detritivorous stream invertebrates, shredders facilitate collectors through their role in producing particles from coarser detritus. While this hypothesis is plausible, we argue that it has not been adequately tested. It has not even been clear what information would be necessary or sufficient to document such an interaction. We outline the evidence which we believe must be sought: it must be established that collectors are particle-limited, that shredder activity produces particles, that shredder activity enhances collector performance, and that the mechanism for this enhancement lies in particle production and not some other process. We review available data that bear on these propositions, and describe a straightforward experiment which could unambiguously test the shredder-collector facilitation hypothesis. Invertebrate faunas of forest streams are often dominated by detritivores which feed on organic matter derived largely from leaf litter. Two major functional groups can be distinguished among them: shredders, which consume coarse particulate organic matter (CPOM), and collectors, which consume fine particles (FPOM) filtered from the water column or gathered from sediments. Shredders process CPOM and produce particles as they feed, and it is widely believed that shredders facilitate collectors as a result of this particle production (e.g. These putative shredder-collector interactions are important for at least three reasons. First, on a local scale, effects of shredders on collector performance have obvious consequences for productivity throughout stream food webs. These effects are likely to have ecological and economic implications beyond the stream itself. For instance, increased collector growth should allow greater productivity of stream fish, which in turn will benefit terrestrial piscivores and commercial and sports fisheries. In addition, the emergent adults of stream collectors can be a major resource for terrestrial and aerial insectivores, and some are also important pests -for instance, black flies. Second, on a much larger spatial scale, shredder-collector facilitation (at the level of whole functional groups) is a major element of the River Continuum Concep

Characterization of an electron conduit between bacteria and the extracellular environment

A number of species of Gram-negative bacteria can use insoluble minerals of Fe(III) and Mn(IV) as extracellular respiratory electron acceptors. In some species of Shewanella, deca-heme electron transfer proteins lie at the extracellular face of the outer membrane (OM), where they can interact with insoluble substrates. To reduce extracellular substrates, these redox proteins must be charged by the inner membrane/periplasmic electron transfer system. Here, we present a spectro-potentiometric characterization of a trans-OM icosa-heme complex, MtrCAB, and demonstrate its capacity to move electrons across a lipid bilayer after incorporation into proteoliposomes. We also show that a stable MtrAB subcomplex can assemble in the absence of MtrC; an MtrBC subcomplex is not assembled in the absence of MtrA; and MtrA is only associated to the membrane in cells when MtrB is present. We propose a model for the modular organization of the MtrCAB complex in which MtrC is an extracellular element that mediates electron transfer to extracellular substrates and MtrB is a trans-OM spanning ß-barrel protein that serves as a sheath, within which MtrA and MtrC exchange electrons. We have identified the MtrAB module in a range of bacterial phyla, suggesting that it is widely used in electron exchange with the extracellular environment

Magnetic resonance imaging-guided phase 1 trial of putaminal AADC gene therapy for Parkinson's disease.

ObjectiveTo understand the safety, putaminal coverage, and enzyme expression of adeno-associated viral vector serotype-2 encoding the complementary DNA for the enzyme, aromatic L-amino acid decarboxylase (VY-AADC01), delivered using novel intraoperative monitoring to optimize delivery.MethodsFifteen subjects (three cohorts of 5) with moderately advanced Parkinson's disease and medically refractory motor fluctuations received VY-AADC01 bilaterally coadministered with gadoteridol to the putamen using intraoperative magnetic resonance imaging (MRI) guidance to visualize the anatomic spread of the infusate and calculate coverage. Cohort 1 received 8.3 × 1011 vg/ml and ≤450 μl per putamen (total dose, ≤7.5 × 1011 vg); cohort 2 received the same concentration (8.3 × 1011 vg/ml) and ≤900 μl per putamen (total dose, ≤1.5 × 1012 vg); and cohort 3 received 2.6 × 1012 vg/ml and ≤900 μl per putamen (total dose, ≤4.7 × 1012 vg). (18)F-fluoro-L-dihydroxyphenylalanine positron emission tomography (PET) at baseline and 6 months postprocedure assessed enzyme activity; standard assessments measured clinical outcomes.ResultsMRI-guided administration of ascending VY-AADC01 doses resulted in putaminal coverage of 21% (cohort 1), 34% (cohort 2), and 42% (cohort 3). Cohorts 1, 2, and 3 showed corresponding increases in enzyme activity assessed by PET of 13%, 56%, and 79%, and reductions in antiparkinsonian medication of -15%, -33%, and -42%, respectively, at 6 months. At 12 months, there were dose-related improvements in clinical outcomes, including increases in patient-reported ON-time without troublesome dyskinesia (1.6, 3.3, and 1.5 hours, respectively) and quality of life.InterpretationNovel intraoperative monitoring of administration facilitated targeted delivery of VY-AADC01 in this phase 1 study, which was well tolerated. Increases in enzyme expression and clinical improvements were dose dependent. ClinicalTrials.gov Identifier: NCT01973543 Ann Neurol 2019;85:704-714

PRESSURE PULSES AT

Voyager 1 (V1) crossed the heliopause into the local interstellar medium (LISM) in 2012. The LISM is a dynamic region periodically disturbed by solar transients with outward-propagating shocks, cosmic-ray intensity changes and anisotropies, and plasma wave oscillations. Voyager 2 (V2) trails V1 and thus may observe the solar transients that are later observed at V1. V2 crossed the termination shock in 2007 and is now in the heliosheath. Starting in 2012, when solar maximum conditions reached V2, five possible merged interaction regions (MIRs) have been observed by V2 in the heliosheath. The timing is consistent with these MIRs driving the transients observed by V1 in the LISM. The largest heliosheath MIR was observed by V2 in late 2015 and should reach V1 in 2018.Jet Propulsion Laboratory (U.S.) (contract 959203

Affect Variability and Predictability: Using Recurrence Quantification Analysis to Better Understand How the Dynamics of Affect Relate to Health

Changes in affect over time have been associated with health outcomes. However, previously utilized measurement methods focus on variability of affect (e.g., standard deviation, root mean squared successive difference) and ignore the more complex temporal patterns of affect over time. These patterns may be an important feature in understanding how the dynamics of affect relate to health. Recurrence quantification analysis (RQA) may help alleviate this problem by assessing temporal characteristics unassessed by past methods. RQA metrics, such as determinism and recurrence, can provide a measure of the predictability of affect over time, indexing how often patterns within affective experiences repeat. In Study 1, we first contrasted RQA metrics with commonly used measures of variability to demonstrate that RQA can further differentiate among patterns of affect. In Study 2, we analyzed the associations between these new metrics and health, namely, depressive and somatic symptoms. We found that RQA metrics predicted health above and beyond mean levels and variability of affect over time. The most desirable health outcomes were observed in people who had high mean positive affect, low mean negative affect, low affect variability, and high affect predictability. These studies are the first to demonstrate the utility of RQA for determining how temporal patterns in affective experiences are important for health outcomes

K+ to pi-mu+mu+ and doubly-charged Higgs

The rate for the lepton-number-violating decay K+ to pi- mu+mu+ is calculated in a model which incorporates doubly-charged Higgs bosons. We find that for reasonable values of the parameters the decay branching ratio may be as large as 2E-16. Although this is a discouragingly small number, it is of the same order of magnitude as the rate mediated by massive Majorana neutrinos.Comment: 8 pages, RevTex, Figure1 is P

Academic attainment in deaf and hard-of-hearing students in distance education

This study compared outcomes in deaf and hard-of-hearing (DHH) students and nondisabled students taking courses by distance learning with the UK Open University in 2012. DHH students who had no additional disabilities were more likely to complete their courses than nondisabled students, and they were just as likely to pass the courses that they completed and to obtain good grades on the courses that they passed. DHH students who had additional disabilities were less likely to complete their courses, less likely to pass the courses that they completed, and less likely to obtain good grades on the courses that they pass than were nondisabled students. It is concluded that hearing loss per se has no effect on academic attainment, but that additional disabilities may have an impact on DHH students’ academic performance

The X-ray Remnant of SN1987A

We present high resolution Chandra observations of the remnant of SN1987A in the Large Magellanic Cloud. The high angular resolution of the Chandra X-ray Observatory (CXO) permits us to resolve the X-ray remnant. We find that the remnant is shell-like in morphology, with X-ray peaks associated with some of the optical hot spots seen in HST images. The X-ray light curve has departed from the linear flux increase observed by ROSAT, with a 0.5-2.0 keV luminosity of 1.5 x 10^35 erg/s in January 2000. We set an upper limit of 2.3 x 10^34 ergs/s on the luminosity of any embedded central source (0.5 - 2 keV). We also present a high resolution spectrum, showing that the X-ray emission is thermal in origin and is dominated by highly ionized species of O, Ne, Mg, and Si.Comment: 16 pages, 3 figures, Accepted for publication in ApJ Letter