16 research outputs found

    Odds ratio (CI) for Coronary Heart Disease Associated with Genotypes of the <i>LTA</i> Gene in ISIS and Other Studies Using Recessive and Dominant Models

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    <p>(A) shows the recessive model and (B) shows the dominant model. Studies are of either the rs909253 SNP (A/G alleles) or the rs1041981 SNP (A/C alleles). The hypothesis-generating study [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0020107#pgen-0020107-b005" target="_blank">5</a>] has been excluded from the combined estimates for all other studies that tested the hypothesised association. Size of the squares is proportional to the variance of the log odds ratio, and horizontal lines represent the 99% CIs, and the width of the diamonds represents the 95% CIs. The associations have not been adjusted for age or sex.</p

    Adjusted hazard ratios for major occlusive vascular disease by number of cardiovascular risk factors at baseline among individuals with diabetes.

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    <p>Stratified by age, sex, and study area and adjusted for education and alcohol consumption. Cardiovascular risk factors: hypertension (self-reported hypertension, mean SBP ≥ 140 mm Hg or diastolic blood pressure ≥ 90 mm Hg), overweight or obesity (BMI ≥ 25 kg/m<sup>2</sup>), ever regular smoking, and physical inactivity (<10 metabolic equivalent of task hours/day). Squares represent the HR, with area inversely proportional to the variance of the log HR. Horizontal lines represent the corresponding 95% confidence intervals.</p
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