Estudio sobre el empleo de macroalgas marinas como suplemento de minerales en vacuno de leche en régimen ecológico

A produción ecolóxica é un sistema global de xestión das explotacións agrícolas e de produción de alimentos que combina as mellores prácticas ambientais, un alto nivel de biodiversidade, a conservación dos recursos naturais, así como a promoción do desenvolvemento rural, a aplicación de normas de benestar animal e un método de produción acorde á preferencia de certos consumidores por produtos feitos a partir de substancias e procesos naturais. O piar fundamental da gandería ecolóxica é a alimentación animal. A normativa da gandería ecolóxica, prevé que polo menos o 60% do alimento nas granxas, debe ser forraxe fresco ou conservado e non permiten o uso rutineiro de vitaminas e minerais o que pode levar a deficiencias de minerais. As prácticas de manexo e a composición da dieta determinan en gran parte o nivel, tanto de elementos esenciais como tóxicos ao que está exposto o gando, e polo tanto, as concentracións destes elementos en produtos de orixe animal. Sabemos que as algas mariñas son ricas nunha ampla gama de aminoácidos, oligoelementos e vitaminas, con todo, e a pesar do alto contido de minerais da maioría das especies de algas, o seu uso como suplemento mineral non foi estudado, agás para o iodo. O obxectivo xeral deste traballo concéntrase en avaliar a posibilidade de utilización de macroalgas mariñas da costa de Galicia como unha fonte de minerais. Para iso, realizaranse os seguintes obxectivos específicos: (i) establecer o perfil mineral do gando leiteiro en España e avaliar se existe unha diferenza entre os sistemas ecolóxicos e convencionais, utilizando análise quimiométrica. (ii) realizar o que cremos ser o primeiro estudo sobre as concentracións de elementos esenciais e tóxicos en leite de granxas ecolóxicas, no norte de España, en comparación coa produción convencional. (iii) establecer a composición mineral (elementos tóxicos e esenciais) en algas do litoral de Galicia (NO España) e realizar un suplemento a base de algas con capacidade de aumentar os niveis de minerais, especialmente iodo e selenio nos animais. (iv) avaliar a viabilidade do uso de algas mariñas da costa de Galicia como unha fonte de minerais, sobre todo iodo e outros minerais en vacas leiteiras en produción ecolóxica. (v) avaliar o efecto da suplementación de algas soas ou en combinación cun suplemento mineral convencional (bolos ruminais) para mellorar o estado mineral de vacún de leite en granxas ecolóxicas e estimar o seu efecto sobre a composición mineral, a produción de leite e a composición (% de graxa, % de proteína e reconto de células somáticas)

The use of seaweed from the Galician coast as a mineral supplement in organic dairy cattle

This study was designed to assess the value of seaweeds from the Galician coast as a source of minerals (especially iodine (I) but also other micro-minerals) in organic dairy cattle. It was conducted in an organic dairy farm in the Lugo province that typically represents the organic milk production in NW Spain. The animal’s diet consisted mainly of local forage (at pasture or as hay and silage in the winter) and 5 kg of purchased concentrate/day per animal (representing 23.5% of feed intake). Based on the mineral composition of the diet, the physiological requirements and the EU maximum authorised levels in feed, a supplement composed by Sea Lettuce (Ulva rigida) (as flakes, 80%), Japanese Wireweed (Sargasum muticum) (flakes, 17.5%) and Furbelows (Saccorhiza polyschides) (powder, 2.5%) was formulated to give 100 g/animal per day. Sixteen Holstein Friesian lactating cows were randomly selected and assigned to the control (n=8) and algae-supplemented groups (n=8). Both groups had exactly the same feeding and management with the exception of the algae supplement, which was mixed with the concentrate feed and given to the animals at their morning milking for 10 weeks. Heparinised blood (for plasma analysis) and milk samples were collected at 2-week intervals and analysed for toxic and trace element concentrations by inductively coupled plasma-mass spectrometry or inductively coupled plasma-optical emission spectrometry. The algae supplement significantly improved the animals’ mineral status, particularly I and selenium that were low on the farm. However, the effect of the algae supplement on the molybdenum status in cattle needs further investigation because of its great relevance on copper metabolism in ruminants. The I supply deserves special attention, since this element is at a very high concentration in brown-algae species and it is excreted in the milk proportionally to its concentration in plasma concentrations (mean±s.e. in the algae-supplemented and control groups were 268±54 and 180±42 µg/l, respectively)This work was supported by the Spanish Government (projectcode AGL2010-21026) and Centro Tecnológico Agroalimentario de Lugo (CETAL)S

Automatic Generation of Integration and Preprocessing Ontologies for Biomedical Sources in a Distributed Scenario

Access to a large number of remote data sources has boosted research in biomedicine, where different biological and clinical research projects are based on collaborative efforts among international organizations. In this scenario, the authors have developed various methods and tools in the area of database integration, using an ontological approach. This paper describes a method to automatically generate preprocessing structures (ontologies) within an ontology-based KDD model. These ontologies are obtained from the analysis of data sources, searching for: (i) valid numerical ranges (using clustering techniques), (ii) different scales, (iii) synonym transformations based on known dictionaries and (iv)typographical errors. To test the method, experiments were carried out with four biomedical databases―containing rheumatoid arthritis, gene expression patterns, biological processes and breast cancer patients― proving the performance of the approach. This method supports experts in data analysis processes, facilitating the detection of inconsistencies

Short communication: The main factors affecting somatic cell count in organic dairy farming

Preventive management practices are essential for maintaining acceptable udder health status, especially in organic farming, in which the use of antimicrobials is restricted. The contribution of the following factors to somatic cell count (SCC) was assessed in 788 cows from 15 organically reared herds in northern Spain: milk production, lactation number, treatments applied, selective dry cow therapy and teat dipping routines. The data were examined by linear logistic regression. Lactation number was the main factor affecting logSCC (β= 0.339, p<0.001) followed in order of importance by milk production (β= -0.205, p<0.001), use of alternative treatments (β=0.153, p<0.001), selective dry cow therapy (β=0.120, p=0.005) and teat dipping routines (β=-0.076, p=0.028). However, the model only explained 17.0% of the total variation in SCC. This variable depends on factors other than those considered here, amongst which udder infection is probably one of the most important. Nonetheless, the study findings enabled us to determine the contribution of the main management factors that should be taken into account to improve udder health status on organic farms

Life-Cycle Assessment and Acoustic Simulation of Drywall Building Partitions with Bio-Based Materials

[EN] The ecological transition is a process the building industry is bound to undertake. This study aimed to develop new bio-based building partition typologies and to determine if they are suitable ecological alternatives to the conventional non-renewable ones used today. This work started with the development of a bio-based epoxy composite board and a waste-based sheep wool acoustic absorbent. Six different partition typologies combining conventional and bio-based materials were analyzed. A drywall partition composed of gypsum plasterboard and mineral wool was used as the baseline. First, a cradle-to-gate life cycle assessment was performed to compare their environmental impacts. Secondly, a mathematical simulation was performed to evaluate their airborne acoustic insulation. The LCA results show a 50% decrease in the amount of CO(2)equivalent emitted when replacing plasterboard with bio-composite boards. The bio-composites lower the overall environmental impact by 40%. In the case of the acoustic absorbents, replacing the mineral wool with cellulose or sheep wool decreases the carbon emissions and the overall environmental impact of the partition from 4% and 6%, respectively. However, while the bio-based acoustic absorbents used offer good acoustic results, the bio-composites have a lower airborne acoustic insulation than conventional gypsum plasterboard.This research was funded by the Spanish Ministry of Economy, Industry, and Competitiveness (BIA2013-41537-R). The project was co-funded by the European Regional Development Fund and it is included in the R+D National Programme for Research Aimed at the Challenges of Society.Quintana-Gallardo, A.; Alba, J.; Rey Tormos, RMD.; Crespo, J.; Guillén Guillamón, IE. (2020). Life-Cycle Assessment and Acoustic Simulation of Drywall Building Partitions with Bio-Based Materials. Polymers. 12(9):1-16. https://doi.org/10.3390/polym12091965S11612

Modelos numéricos para el estudio de incendios en túneles

Si se estudian los distintos métodos existentes actualmente para el estudio del comportamiento de los incendios en túneles no parece que se disponga de una solución única y definitiva. Tanto los métodos numéricos como los modelos fisicos a escala tienen sus limitaciones y ventajas. Por tanto, puede decirse que se trata de enfoques complementarios y que deben emplearse todos cuando la importancia de la obra así lo requiera.Desde el punto de vista del proyecto cabe indicar la necesidad de que los cálculos no se limiten al dimensionamiento del sistema de ventilación sino que incluyan pautas de actuación sencillas que puedan ser seguidas de forma refleja por los responsables del Centro de Control en los primeros momentos del incendio ya que ello es clave en el éxito del proceso de evacuación. En este sentido es perentorio el desarrollo de simuladores numéricos que puedan ser utilizados en el entrenamiento y formación de los operadores del Centro de Control

Aplicaciones de la citología exfoliativa en el diagnóstico del cáncer oral

La citología exfoliativa es una técnica sencilla, no agresiva y bien aceptada por los pacientes, por lo que podría ser útil en el diagnóstico precoz del cáncer oral. Sin embargo, su utilización como método diagnóstico de atipias epiteliales y especialmente del carcinoma oral de células escamosas ha perdido importancia, sobre todo debido a su baja sensibilidad representada por el elevado número de resultados falsos negativos. Se atribuye esta baja sensibilidad a diversos factores, entre ellos: toma inadecuada de la muestra, error en la técnica e interpretación subjetiva de los hallazgos citológicos. Afortunadamente, en los últimos tiempos, el desarrollo del análisis cuantitativo, la citomorfología, el análisis del ADN, la detección de marcadores tumorales y el análisis molecular ha contribuido al resurgir de esta técnica. El objetivo de este trabajo es hacer una breve revisión sobre las aplicaciones de la citología exfoliativa en el diagnóstico del cáncer oral.Exfoliative cytology is a simple non-aggressive technique that is well accepted by the patient, and that is therefore an attractive option for the early diagnosis of oral cancer, including epithelial atypias and especially squamous cell carcinoma. However, traditional exfoliative cytology methods show low sensitivity (i.e. a high proportion of false negatives) in the diagnosis of these pathologies. This low sensitivity is attributable to various factors, including inadequate sampling, procedural errors, and the need for subjective interpretation of the findings. More recently, the continuing development of automated cytomorphometric methods, DNA content determination, tumour marker detection, and diverse molecular-level analyses has contributed to renewed interest in exfoliative cytology procedures for the diagnosis of oral cancer. The present study briefly reviews developments in these areas

CDAPubMed: a browser extension to retrieve EHR-based biomedical literature

Over the last few decades, the ever-increasing output of scientific publications has led to new challenges to keep up to date with the literature. In the biomedical area, this growth has introduced new requirements for professionals, e.g., physicians, who have to locate the exact papers that they need for their clinical and research work amongst a huge number of publications. Against this backdrop, novel information retrieval methods are even more necessary. While web search engines are widespread in many areas, facilitating access to all kinds of information, additional tools are required to automatically link information retrieved from these engines to specific biomedical applications. In the case of clinical environments, this also means considering aspects such as patient data security and confidentiality or structured contents, e.g., electronic health records (EHRs). In this scenario, we have developed a new tool to facilitate query building to retrieve scientific literature related to EHRs. Results: We have developed CDAPubMed, an open-source web browser extension to integrate EHR features in biomedical literature retrieval approaches. Clinical users can use CDAPubMed to: (i) load patient clinical documents, i.e., EHRs based on the Health Level 7-Clinical Document Architecture Standard (HL7-CDA), (ii) identify relevant terms for scientific literature search in these documents, i.e., Medical Subject Headings (MeSH), automatically driven by the CDAPubMed configuration, which advanced users can optimize to adapt to each specific situation, and (iii) generate and launch literature search queries to a major search engine, i.e., PubMed, to retrieve citations related to the EHR under examination. Conclusions: CDAPubMed is a platform-independent tool designed to facilitate literature searching using keywords contained in specific EHRs. CDAPubMed is visually integrated, as an extension of a widespread web browser, within the standard PubMed interface. It has been tested on a public dataset of HL7-CDA documents, returning significantly fewer citations since queries are focused on characteristics identified within the EHR. For instance, compared with more than 200,000 citations retrieved by breast neoplasm, fewer than ten citations were retrieved when ten patient features were added using CDAPubMed. This is an open source tool that can be freely used for non-profit purposes and integrated with other existing systems

The main factors affecting somatic cell count in organic dairy farming

Preventive management practices are essential for maintaining acceptable udder health status, especially in organic farming, in which the use of antimicrobials is restricted. The contribution of the following factors to somatic cell count (SCC) was assessed in 788 cows from 15 organically reared herds in northern Spain: milk production, lactation number, treatments applied, selective dry cow therapy and teat dipping routines. The data were examined by linear logistic regression. Lactation number was the main factor affecting logSCC (β= 0.339, p<0.001) followed in order of importance by milk production (β= -0.205, p<0.001), use of alternative treatments (β=0.153, p<0.001), selective dry cow therapy (β=0.120, p=0.005) and teat dipping routines (β=-0.076, p=0.028). However, the model only explained 17.0% of the total variation in SCC. This variable depends on factors other than those considered here, amongst which udder infection is probably one of the most important. Nonetheless, the study findings enabled us to determine the contribution of the main management factors that should be taken into account to improve udder health status on organic farms.Spanish Government (AGL2010-21026); Centro Tecnológico Agroalimentario de Lugo, Spain (CETAL); IO is in receipt of a FPU fellowship (Ref. FPU14/01473) from the Spanish Ministry of Education, Culture and SportsS