Searching for the dual of the Maxwell-Chern-Simons model minimally coupled to dynamical U(1) charged matter

The possibility of dual equivalence between the self-dual and the Maxwell-Chern-Simons (MCS) models when the latter is coupled to dynamical, U(1) fermionic charged matter is examined. The proper coupling in the self-dual model is then disclosed using the iterative gauge embedding approach. We found that the self-dual potential needs to couple directly to the Chern-Kernel of the source in order to establish this equivalence besides the need for a self-interaction term to render the matter sector unchanged.Comment: 4 pages, RevTeX, new references, accepted for publication on Phys. Lett.

No cosmological domain wall problem for weakly coupled fields

After inflation occurs, a weakly coupled scalar field will in general not be in thermal equilibrium but have a distribution of values determined by the inflationary Hubble parameter. If such a field subsequently undergoes discrete symmetry breaking, then the different degenerate vacua may not be equally populated so the domain walls which form will be `biased' and the wall network will subsequently collapse. Thus the cosmological domain wall problem may be solved for sufficiently weakly coupled fields in a post-inflationary universe. We quantify the criteria for determining whether this does happen, using a Higgs-like potential with a spontaneously broken $Z_2$ symmetry.Comment: 17 pages, 4 figures (Revtex), clarifying Comments added in Introduction; to appear in Phys. Rev

Caring for people with Alzheimer's disease who show defensive behaviours. Part 1: Four essential pieces of nursing knowledge

When caring for people living with Alzheimer's disease (AD) and showing aggressive behaviours, nurses must perform a knowledge-based nursing practice to better understand the people's needs and support them. This article aims to present a structure for the knowledge essential for nurses caring for people living with Alzheimer's disease who show defensive behaviours. People living with AD some times show defensive behaviours that have disastrous consequences for them, their family members, the other residents, and the formal caregivers. Rather than considering these behaviours as being aggressive and disruptive, nurses must understand that they are protective and defensive. Because of the important role that nurses have in the care of people living with AD, they must possess specific knowledge. This discursive paper is based on the literature of defensive behaviours and integrates the Fundamentals of Care Framework. We use Kim's perspective regarding the knowledge-based practice and the knowledge-use in nursing practice. Several dimensions that must be considered for the nursing practice for the elderly living with AD are introduced. This permits to present a clinical gerontological nursing process centred on the relationship with the person living with AD and their family. Moreover, a mid-paradigm for nursing care of these people is introduced. Then, essential nursing knowledge for the care of people living with AD is presented in four parts, which are 1) Characteristics of AD, 2) Goals of the behaviours, 3) Contributing factors, and 4) Ecobiopsychosocial and pharmacological interventions related to the person and family's needs. The specific structure of knowledge permits to precisely identify pieces of knowledge nurses should possess and nursing students should learn in order to take care of people living with AD and their families

Nonlinear Realization of N=2 Superconformal Symmetry and Brane Effective Actions

Due to the incompatibility of the nonlinear realization of superconformal symmetry and dilatation symmetry with the dilaton as the compensator field, in the present paper it shows an alternative mechanism of spontaneous breaking the N=2 superconformal symmetry to the N=0 case. By using the approach of nonlinear transformations it is found that it leads to a space-filling brane theory with Weyl scale W(1,3) symmetry. The dynamics of the resulting Weyl scale invariant brane, along with that of other Nambu-Goldstone fields, is derived in terms of the building blocks of the vierbein and the covariant derivative from the Maurer-Cartan oneforms. A general coupling of the matter fields localized on the brane world volume to these NG fields is also constructed.Comment: 22 pages, more references and comments are adde

The gene coding for variant hepatic nuclear factor 1 ( Tcf-2 ), maps between the Edp-1 and Erba genes on mouse Chromosome 11

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46992/1/335_2004_Article_BF00352466.pd

Topological R4R^4 Inflation

We consider the possibility that higher-curvature corrections could drive inflation after the compactification to four dimensions. Assuming that the low-energy limit of the fundamental theory is eleven-dimensional supergravity to the lowest order, including curvature corrections and taking the descent from eleven dimensions to four via an intermediate five-dimensional theory, as favored by recent considerations of unification at some scale around $\sim 10^{16}$ GeV, we may obtain a simple model of inflation in four dimensions. The effective degrees of freedom are two scalar fields and the metric. The scalars arise as the large five-dimensional modulus and the self-interacting conformal mode of the metric. The effective potential has a local maximum in addition to the more usual minimum. However, the potential is quite flat at the top, and admits topological inflation. We show that the model can resolve cosmological problems and provide a mechanism for structure formation with very little fine tuning.Comment: 25 pages, latex, 2 eps figures, minor changes, accepted for publication in Phys. Rev.

Multimeric single-domain antibody complexes protect against bunyavirus infections

The World Health Organization has included three bunyaviruses posing an increasing threat to human health on the Blueprint list of viruses likely to cause major epidemics and for which no, or insufficient countermeasures exist. Here, we describe a broadly applicable strategy, based on llama-derived single-domain antibodies (VHHs), for the development of bunyavirus biotherapeutics. The method was validated using the zoonotic Rift Valley fever virus (RVFV) and Schmallenberg virus (SBV), an emerging pathogen of ruminants, as model pathogens. VHH building blocks were assembled into highly potent neutralizing complexes using bacterial superglue technology. The multimeric complexes were shown to reduce and prevent virus-induced morbidity and mortality in mice upon prophylactic administration. Bispecific molecules engineered to present two different VHHs fused to an Fc domain were further shown to be effective upon therapeutic administration. The presented VHH-based technology holds great promise for the development of bunyavirus antiviral therapies

Use of SMS texts for facilitating access to online alcohol interventions: a feasibility study

A41 Use of SMS texts for facilitating access to online alcohol interventions: a feasibility study In: Addiction Science & Clinical Practice 2017, 12(Suppl 1): A4