Analogue modelling of basin inversion: a review and future perspectives

Basin inversion involves the reversal of subsidence in a basin due to compressional tectonic forces, leading to uplift of the basin's sedimentary infill. Detailed knowledge of basin inversion is of great importance for scientific, societal, and economic reasons, spurring continued research efforts to better understand the processes involved. Analogue tectonic modelling forms a key part of these efforts, and analogue modellers have conducted numerous studies of basin inversion. In this review paper we recap the advances in our knowledge of basin inversion processes acquired through analogue modelling studies, providing an up-to-date summary of the state of analogue modelling of basin inversion. We describe the different definitions of basin inversion that are being applied by researchers, why basin inversion has been historically an important research topic and what the general mechanics involved in basin inversion are. We subsequently treat the wide range of different experimental approaches used for basin inversion modelling, with attention to the various materials, set-ups, and techniques used for model monitoring and analysing the model results. Our new systematic overviews of generalized model results reveal the diversity of these results, which depend greatly on the chosen set-up, model layering and (oblique) kinematics of inversion, and 3D along-strike structural and kinematic variations in the system. We show how analogue modelling results are in good agreement with numerical models, and how these results help researchers to better understand natural examples of basin inversion. In addition to reviewing the past efforts in the field of analogue modelling, we also shed light on future modelling challenges and identify a number of opportunities for follow-up research. These include the testing of force boundary conditions, adding geological processes such as sedimentation, transport, and erosion; applying state-of-the-art modelling and quantification techniques; and establishing best modelling practices. We also suggest expanding the scope of basin inversion modelling beyond the traditional upper crustal 'North Sea style' of inversion, which may contribute to the ongoing search for clean energy resources. It follows that basin inversion modelling can bring valuable new insights, providing a great incentive to continue our efforts in this field. We therefore hope that this review paper will form an inspiration for future analogue modelling studies of basin inversion

Effects of exercise training on airway responsiveness and airway cells in healthy subjects

J Appl Physiol. 2010 Aug;109(2):288-94. Epub 2010 Jun 10. Effects of exercise training on airway responsiveness and airway cells in healthy subjects. Scichilone N, Morici G, Zangla D, Chimenti L, Dav\uec E, Reitano S, Patern\uf2 A, Santagata R, Togias A, Bellia V, Bonsignore MR. SourceDept. of Internal Medicine, Div. of Pulmonology (DIBIMIS Univ. of Palermo, "Villa Sofia-Cervello" Hospital, Via Trabucco 180, 90146 Palermo, Italy. [email protected] Abstract Airway responsiveness to methacholine (Mch) in the absence of deep inspirations (DIs) is lower in athletes compared with sedentary individuals. In this prospective study, we tested the hypothesis that a training exercise program reduces the bronchoconstrictive effect of Mch. Ten healthy sedentary subjects (M/F: 3/7; mean + or - SD age: 22 + or - 3 yr) entered a 10-wk indoor rowing exercise program on rowing ergometer and underwent Mch bronchoprovocation in the absence of DIs at baseline, at weeks 5 and 10, as well as 4-6 wk after the training program was completed. Exercise-induced changes on airway cells and markers of airway inflammation were also assessed by sputum induction and venous blood samples. Mean power output during the 1,000 m test was 169 + or - 49 W/stroke at baseline, 174 + or - 49 W/stroke at 5 wk, and 200 + or - 60 W/stroke at 10 wk of training (P < 0.05). The median Mch dose used at baseline was 50 mg/ml (range 25-75 mg/ml) and remained constant per study design. At the pretraining evaluation, the percent reduction in the primary outcome, the inspiratory vital capacity (IVC) after inhalation of Mch in the absence of DIs was 31 +/- 13%; at week 5, the Mch-induced reduction in IVC was 22 + or - 19%, P = 0.01, and it further decreased to 15 + or - 11% at week 10 (P = 0.0008). The percent fall in IVC 4-6 wk after the end of training was 15 + or - 11% (P = 0.87 vs. end of training). Changes in airway cells were not associated with changes in airway responsiveness. Our data show that a course of exercise training can attenuate airway responsiveness against Mch inhaled in the absence of DIs in healthy subjects and suggest that a sedentary lifestyle may favor development of airways hyperresponsiveness. Comment in J Appl Physiol. 2010 Aug;109(2):267-8. PMID:20538849[PubMed - in process

Analogue modelling of basin inversion: a review and future perspectives

Basin inversion involves the reversal of subsidence in a basin due to compressional tectonic forces, leading to uplift of the basin's sedimentary infill. Detailed knowledge of basin inversion is of great importance for scientific, societal, and economic reasons, spurring continued research efforts to better understand the processes involved. Analogue tectonic modelling forms a key part of these efforts, and analogue modellers have conducted numerous studies of basin inversion. In this review paper we recap the advances in our knowledge of basin inversion processes acquired through analogue modelling studies, providing an up-to-date summary of the state of analogue modelling of basin inversion. We describe the different definitions of basin inversion that are being applied by researchers, why basin inversion has been historically an important research topic and what the general mechanics involved in basin inversion are. We subsequently treat the wide range of different experimental approaches used for basin inversion modelling, with attention to the various materials, set-ups, and techniques used for model monitoring and analysing the model results. Our new systematic overviews of generalized model results reveal the diversity of these results, which depend greatly on the chosen set-up, model layering and (oblique) kinematics of inversion, and 3D along-strike structural and kinematic variations in the system. We show how analogue modelling results are in good agreement with numerical models, and how these results help researchers to better understand natural examples of basin inversion. In addition to reviewing the past efforts in the field of analogue modelling, we also shed light on future modelling challenges and identify a number of opportunities for follow-up research. These include the testing of force boundary conditions, adding geological processes such as sedimentation, transport, and erosion; applying state-of-the-art modelling and quantification techniques; and establishing best modelling practices. We also suggest expanding the scope of basin inversion modelling beyond the traditional upper crustal “North Sea style” of inversion, which may contribute to the ongoing search for clean energy resources. It follows that basin inversion modelling can bring valuable new insights, providing a great incentive to continue our efforts in this field. We therefore hope that this review paper will form an inspiration for future analogue modelling studies of basin inversion.</p

Estudios en Historia Moderna desde una visión Atlántica: Libro homenaje a la trayectoria de la profesora María Inés Carzolio

Este libro homenaje se formula como un diálogo abierto entre grupos de investigación europeos y americanos sobre problemáticas referidas a una visión Atlántica de la proyección de los Imperios Ibéricos en la Edad Moderna. Los ejes convocantes son aquellos que a lo largo de su dilatada trayectoria en la investigación histórica ha desarrollado y publicado la Dra. María Inés Carzolio, tanto en Argentina como en el extranjero: Las raíces medievales de la Europa Moderna, las monarquías del Antiguo Régimen, la organización del espacio social y los agentes sociales en la modernidad, cuestiones sobre creencias y religiosidad, estudios urbanos y, finalmente, problemáticas en torno al campo discursivo y cultural.Facultad de Humanidades y Ciencias de la Educació

The performance of deterministic and stochastic interest rate risk measures : Another Question of Dimensions?

The efficiency of traditional and stochastic interest rate risk measures is compared under one-, two-, and three-factor no-arbitrage Gauss-Markov term structure models, and for different immunization periods. The empirical analysis, run on the German Treasury bond market from January 2000 to December 2010, suggests that: i) Stochastic interest rate risk measures provide better portfolio immunization than the Fisher-Weil duration; and ii) The superiority of the stochastic risk measures is more evident for multi-factor models and for longer investment horizons. These findings are supported by a first-order stochastic dominance analysis, and are robust against yield curve estimation errors.info:eu-repo/semantics/publishedVersio

The BINGO project: II. Instrument description

Context. The measurement of diffuse 21-cm radiation from the hyperfine transition of neutral hydrogen (Hi signal) in different redshifts is an important tool for modern cosmology. However, detecting this faint signal with non-cryogenic receivers in single-dish telescopes is a challenging task. The BINGO (Baryon Acoustic Oscillations from Integrated Neutral Gas Observations) radio telescope is an instrument designed to detect baryonic acoustic oscillations (BAOs) in the cosmological Hi signal, in the redshift interval 0:127 ≤ z ≤ 0:449. Aims. This paper describes the BINGO radio telescope, including the current status of the optics, receiver, observational strategy, calibration, and the site. Methods. BINGO has been carefully designed to minimize systematics, being a transit instrument with no moving dishes and 28 horns operating in the frequency range 980 ≤ v ≤ 1260 MHz. Comprehensive laboratory tests were conducted for many of the BINGO subsystems and the prototypes of the receiver chain, horn, polarizer, magic tees, and transitions have been successfully tested between 2018-2020. The survey was designed to cover ∼13% of the sky, with the primary mirror pointing at declination δ = -15°. The telescope will see an instantaneous declination strip of 14:75. Results. The results of the prototype tests closely meet those obtained during the modeling process, suggesting BINGO will perform according to our expectations. After one year of observations with a 60% duty cycle and 28 horns, BINGO should achieve an expected sensitivity of 102μK per 9.33MHz frequency channel, one polarization, and be able to measure the Hi power spectrum in a competitive time frame

The quality of life of patients with genital warts: a qualitative study

<p>Abstract</p> <p>Background</p> <p>Genital warts, which are caused by infection with human papillomavirus (HPV), are one of the most common sexually transmitted diseases in Europe. Although genital warts are commonly perceived as a non-serious condition, treatment is often long, of varying effectiveness and the recurrence rate is high. Very few studies have been performed on the personal consequences of genital warts. The aim of this qualitative study, set in Denmark, was to examine the ways in which genital warts may affect patients' quality of life.</p> <p>Methods</p> <p>To obtain an in-depth understanding of patients' perceptions of genital warts, we used qualitative focus-group interviews with five men and five women aged between 18 and 30 years who had genital warts. The interview guide was based on a literature review that identified important issues and questions. The data were analysed using a medical anthropological approach.</p> <p>Results</p> <p>Patients' experiences were related to cultural conceptions of venereal diseases and the respective identities and sexuality of the sexes. The disease had negative psychological and social effects both for men and for women and it affected their sex and love lives, in particular. The psychological burden of the disease was increased by the uncertain timeline and the varying effectiveness of treatment. We identified a need for more patient information about the disease and its psycho-sexual aspects.</p> <p>Conclusions</p> <p>The men and women participating in this study considered their quality of life to be significantly lowered because of genital warts. The experiences described by the participants give insights that may be valuable in treatment and counselling.</p> <p>The quadrivalent HPV vaccine that has now been added to the childhood vaccination programme for girls in Denmark for the prevention of cervical cancer can also prevent 90% of cases of genital warts. Our results suggest that HPV vaccination could considerably reduce the largely unacknowledged psychological and social burden associated with genital warts, in men as well as women.</p